Ferroelectric Behavior of Nano-Layered Heterostructures Composed of Ferroelectric - Linear Dielectric Organic Layers

Thin-film heterostructures comprising ferroelectric (FE) copolymer layers of vinylidene fluoride with trifluoroethylene (PVDF/TrFE) and linear dielectric (LD) layers of azodye prepared by Langmuir-Blodgett technique are obtained and studied. A simple physical model of a local electric field amplification in layers of FE and LD are presented. Experimental studies of the ferroelectric switching confirm that, for heterostructures, the external effective coercitive voltage decreases and the switched polarization increases. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3514

β-Maleimide substituted meso-arylporphyrins: Synthesis, transformations, physico-chemical and antitumor properties

The maleimide moiety is widely used in drug design. To explore the properties of maleimide containing photosensitizers we obtained a series of new β-maleimide functionalized meso-arylporphyrins through acylation of β-amino group in porphyrins with maleic anhydride followed by condensation of maleic acid monoamides. The selective reactivity of porphyrin maleimides toward thiols was demonstrated using mercaptocarboranes and cysteine. New derivatives retained the ability of tetrapyrrolic macrocyclic compounds to absorb light in visible spectral region and to generate triplet states and reactive oxygen species upon photoactivation. Importantly, illumination of cells loaded with a cell permeable 2-{3-[(o-carboran-1′-yl)thio]pyrrolidine-2,5-dione-1-yl}-5,10,15,20-tetraphenylporphyrin triggered rapid (within the initial minutes) generation of superoxide anion radical concomitantly with a decrease of mitochondrial membrane potential, and then the loss of the plasma membrane integrity and cell death. Thus, the maleimide-substituted porphyrins represent a new chemotype of polyfunctionalized compounds for an in-depth investigation as photosensitizers in cancer and beyond. © 201