Introducció de material exòtic per a l'obtenció de blat de moro farratger: resultats preliminars

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Cantabou : revista del CPR d'Inca

Resumen tomado de la publicaciónSe desarrolla una experiencia educativa en la que se tratan los contenidos matemáticos del currículum a través de un eje temático concreto: la Jaia Corema. La Jaia Corema es un personaje de la tradición catalana representado por una mujer de avanzada edad con siete piernas que se encarga de que los niños coman pescado durante los días de Cuaresma. Además de los contenidos de tipo matemático (medida, peso, cálculo, lectura de mapas, etc.), se trabajan contenidos lingüísticos (comunicación, expresión oral y escrita) y artísticos (composición e interpretación de una canción, representación de una danza, trabajo de manualidades, etc.).BalearesRedined Illes Balears; Universitat de les Illes Balears. Edifici Guillem Cifre de Colonya. Ctra. de Valldemossa, Km 7,5; 07122 Palma; +34971172792; +34971173190; [email protected]

Translocation (3;5)(q21;q34) in erythroleukemia: A molecular and in situ hybridization study

Translocation (3;5) is an uncommon karyotypic aberration in acute myeloid leukemia (AML). With the exception of M3, t(3;5) has been reported in every other subtype of AML, being most frequently associated with AML M6. Although a variety of breakpoints have been described, it has been suggested that the breakpoints in t(3;5) of all the reported cases should be assigned to 3q25.1 and 5q34. Recently, the breakpoints in three pediatric cases of AML M2 with t(3;5) were cloned and shown to involve the myelodysplasia/myeloid leukemia factor I (MLF1) gene on 3q25.1 and the nucleophosmin (NPM) gene on 5q34, generating a chimeric NPM/MLF1 transcript. An adult case of indolent erythroleukemia was found on karyotypic analysis to have t(3;5)(q21;q34). In about 60% of cells, the translocation was unbalanced, resulting in loss of the der(3) chromosome, implying that the critical leukemogenic sequence might reside on the der(5) chromosome. Molecular analysis of this case, however, failed to show rearrangement of the NPM gene and an MLF1/NPM transcript. A review of other reported cases of AML M6 with t(3;5) showed that the commonest breakpoint on chromosome 3 was also assigned to 3q21, as in our case. The considerable clinical, pathologic, cytogenetic and molecular differences observed in AML with t(3;5) suggest that these cases might be heterogeneous.link_to_subscribed_fulltex