The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability

Chromobacterium violaceum is one of millions of species of free-living microorganisms that populate the soil and water in the extant areas of tropical biodiversity around the world. Its complete genome sequence reveals (i) extensive alternative pathways for energy generation, (ii) ≈500 ORFs for transport-related proteins, (iii) complex and extensive systems for stress adaptation and motility, and (iv) wide-spread utilization of quorum sensing for control of inducible systems, all of which underpin the versatility and adaptability of the organism. The genome also contains extensive but incomplete arrays of ORFs coding for proteins associated with mammalian pathogenicity, possibly involved in the occasional but often fatal cases of human C. violaceum infection. There is, in addition, a series of previously unknown but important enzymes and secondary metabolites including paraquat-inducible proteins, drug and heavy-metal-resistance proteins, multiple chitinases, and proteins for the detoxification of xenobiotics that may have biotechnological applications

Clonal nature of enterotoxigenic Escherichia coli serotype O6 : H16 revealed by randomly amplified polymorphic DNA analysis

Fil: Pacheco, Ana B. F. Universidade Federal do Rio de Janeiro. Instituto de Biofisica Carlos Chagas Filho; Brasil.Fil: Soares, Kelen C. Universidade Federal do Rio de Janeiro. Instituto de Biofisica Carlos Chagas Filho; Brasil.FIl: de Almeida, Darcy F. Universidade Federal do Rio de Janeiro. Instituto de Biofisica Carlos Chagas Filho; Brasil.Fil: Viboud, Gloria I. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.Fil: Binsztein, Norma. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.Fil: Ferreira, Luis C. S. Universidade Federal do Rio de Janeiro. Instituto de Biofisica Carlos Chagas Filho; Brasil.The genetic relatedness among 29 enterotoxigenic Escherichia coli strains of serotype O6:H16 was investigated by randomly amplified polymorphic DNA (RAPD) analysis. The strains were isolated in different parts of the world, displayed CS1-CS3 or CS2-CS3 profiles, and expressed heat-labile toxin (LT) and heat-stable toxin; a single strain expressed only LT. Ten RAPD types were distinguished and showed significant similarity, having on average 82% of the amplified bands in common. These results indicated that, irrespective of the different geographical origin or virulence factors, these strains belonged to a widespread clonal group

Clonal nature of enterotoxigenic Escherichia coli serotype O6 : H16 revealed by randomly amplified polymorphic DNA analysis

Fil: Pacheco, Ana B. F. Universidade Federal do Rio de Janeiro. Instituto de Biofisica Carlos Chagas Filho; Brasil.Fil: Soares, Kelen C. Universidade Federal do Rio de Janeiro. Instituto de Biofisica Carlos Chagas Filho; Brasil.FIl: de Almeida, Darcy F. Universidade Federal do Rio de Janeiro. Instituto de Biofisica Carlos Chagas Filho; Brasil.Fil: Viboud, Gloria I. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.Fil: Binsztein, Norma. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.Fil: Ferreira, Luis C. S. Universidade Federal do Rio de Janeiro. Instituto de Biofisica Carlos Chagas Filho; Brasil.The genetic relatedness among 29 enterotoxigenic Escherichia coli strains of serotype O6:H16 was investigated by randomly amplified polymorphic DNA (RAPD) analysis. The strains were isolated in different parts of the world, displayed CS1-CS3 or CS2-CS3 profiles, and expressed heat-labile toxin (LT) and heat-stable toxin; a single strain expressed only LT. Ten RAPD types were distinguished and showed significant similarity, having on average 82% of the amplified bands in common. These results indicated that, irrespective of the different geographical origin or virulence factors, these strains belonged to a widespread clonal group

Clonal Nature of Enterotoxigenic Escherichia coli Serotype O6:H16 Revealed by Randomly Amplified Polymorphic DNA Analysis

The genetic relatedness among 29 enterotoxigenic Escherichia coli strains of serotype O6:H16 was investigated by randomly amplified polymorphic DNA (RAPD) analysis. The strains were isolated in different parts of the world, displayed CS1-CS3 or CS2-CS3 profiles, and expressed heat-labile toxin (LT) and heat-stable toxin; a single strain expressed only LT. Ten RAPD types were distinguished and showed significant similarity, having on average 82% of the amplified bands in common. These results indicated that, irrespective of the different geographical origin or virulence factors, these strains belonged to a widespread clonal group

Síndrome de turcot relato de dois casos

Os autores descrevem dois pacientes com associação de polipose intestinal e tumor do sistema nervoso central (síndrome de Turcot), discutindo aspectos clínicos, genéticos e terapêuticos