From Data to Software to Science with the Rubin Observatory LSST

The Vera C. Rubin Observatory Legacy Survey of Space and Time (LSST) dataset will dramatically alter our understanding of the Universe, from the origins of the Solar System to the nature of dark matter and dark energy. Much of this research will depend on the existence of robust, tested, and scalable algorithms, software, and services. Identifying and developing such tools ahead of time has the potential to significantly accelerate the delivery of early science from LSST. Developing these collaboratively, and making them broadly available, can enable more inclusive and equitable collaboration on LSST science. To facilitate such opportunities, a community workshop entitled "From Data to Software to Science with the Rubin Observatory LSST" was organized by the LSST Interdisciplinary Network for Collaboration and Computing (LINCC) and partners, and held at the Flatiron Institute in New York, March 28-30th 2022. The workshop included over 50 in-person attendees invited from over 300 applications. It identified seven key software areas of need: (i) scalable cross-matching and distributed joining of catalogs, (ii) robust photometric redshift determination, (iii) software for determination of selection functions, (iv) frameworks for scalable time-series analyses, (v) services for image access and reprocessing at scale, (vi) object image access (cutouts) and analysis at scale, and (vii) scalable job execution systems. This white paper summarizes the discussions of this workshop. It considers the motivating science use cases, identified cross-cutting algorithms, software, and services, their high-level technical specifications, and the principles of inclusive collaborations needed to develop them. We provide it as a useful roadmap of needs, as well as to spur action and collaboration between groups and individuals looking to develop reusable software for early LSST science.Comment: White paper from "From Data to Software to Science with the Rubin Observatory LSST" worksho

From Data to Software to Science with the Rubin Observatory LSST

editorial reviewedThe Vera C. Rubin Observatory Legacy Survey of Space and Time (LSST) dataset will dramatically alter our understanding of the Universe, from the origins of the Solar System to the nature of dark matter and dark energy. Much of this research will depend on the existence of robust, tested, and scalable algorithms, software, and services. Identifying and developing such tools ahead of time has the potential to significantly accelerate the delivery of early science from LSST. Developing these collaboratively, and making them broadly available, can enable more inclusive and equitable collaboration on LSST science. To facilitate such opportunities, a community workshop entitled "From Data to Software to Science with the Rubin Observatory LSST" was organized by the LSST Interdisciplinary Network for Collaboration and Computing (LINCC) and partners, and held at the Flatiron Institute in New York, March 28-30th 2022. The workshop included over 50 in-person attendees invited from over 300 applications. It identified seven key software areas of need: (i) scalable cross-matching and distributed joining of catalogs, (ii) robust photometric redshift determination, (iii) software for determination of selection functions, (iv) frameworks for scalable time-series analyses, (v) services for image access and reprocessing at scale, (vi) object image access (cutouts) and analysis at scale, and (vii) scalable job execution systems. This white paper summarizes the discussions of this workshop. It considers the motivating science use cases, identified cross-cutting algorithms, software, and services, their high-level technical specifications, and the principles of inclusive collaborations needed to develop them. We provide it as a useful roadmap of needs, as well as to spur action and collaboration between groups and individuals looking to develop reusable software for early LSST science

Análisis estadístico mediante el uso de modelos de regresión para explicar las propiedades funcionales de concentrados proteícos

En el presente trabajo se proponen los siguientes objetivos: - Determinar la capacidad emulsificante de los concentrados proteicos obtenidos de las especies tilapia (Orochromis niloticá) y guavina (Dormitatus maculatus). - Determinar el efecto que ejerce tanto la concentración proteica, como la temperatura sobre la capacidad de formar emulsiones y la estabilidad de éstas. - Implementar el uso de modelos de regresión o series de tiempo, que permitan explicar los cambios en las propiedades funcionales de los concentrados proteicos

Películas comestibles a base de almidón nanoestructurado como material de barrera a la humedad

The packaging materials provide physical protection and create the appropriate physicochemical conditions to give an adequate shelf life. Recently, the food industry has proposed to incorporate nanocomposites into edible films that degrade in a short period of time without causing environmental problems. The objective of this research was to develop an edible film using nanostructured starch, which can serve as a packaging, resistant to moisture, stable that can extend the shelf life of food and additionally environmental benefits. The effects of nanostructured starch on the physical and structural properties of an edible film were studied in terms of thickness, water solubility, diffusion, water vapor permeability (WVP) and water vapor transmission rate (WVTR). The results showed that the edible films formulated with nanostructured starch had the lowest thickness. Furthermore, the solubility in water, the diffusion coefficient, WVP and WVTR were lower for these films. The nanostructuring of corn starch made it possible to obtain edible films with excellent water barrier properties without modifying the structural properties of the polymer matrix, which could constitute an alternative for food packaging.Los materiales de empaque proporcionan protección física y crean las condiciones fisicoquímicas apropiadas para proporcionar una vida útil adecuada. Recientemente, la industria alimentaria ha propuesto incorporar nanocompuestos a películas comestibles que se degraden en un periodo corto, sin causar problemas medioambientales. El objetivo de esta investigación fue desarrollar una película comestible resistente a la humedad, utilizando almidón nanoestructurado, que pueda servir de empaque para aumentar la vida útil de los alimentos, sin afectar el medioambiente. Los efectos del almidón nanoestructurado sobre las propiedades físicas y estructurales de una película comestible fueron estudiados en términos de espesor, solubilidad en agua, difusión, permeabilidad al vapor de agua (PVA), velocidad de transmisión de vapor de agua (VTVA) y comparados a las películas de almidón nativo. Los resultados mostraron que las películas comestibles formuladas con almidón nanoestructurado presentaron menor espesor, comparadas a las elaboradas con almidón nativo, además, los valores de la solubilidad en agua, el coeficiente de difusión, PVA y VTVA fueron menores para las películas nanoestructuradas, con respecto a las de almidón nativo. La nanoestructuración del almidón de maíz permitió obtener películas comestibles con excelentes propiedades de barrera a la humedad, sin modificar las propiedades estructuralesde la matriz del polímero, lo que podría constituir una alternativa para el empaque de alimentos

Quinoa leaf as a nutritional alternative

Chenopodium quinoa is an herbaceous plant that possesses green polymorphic leaves. They are traditionally consumed in America and are considered nutritive vegetables. Most vegetables are considered valuable sources of micronutrients, such as mineral, vitamins, carbohydrates and dietetic fiber; however, because they are poor in proteins, they are considered to have no energetic value. The consumption of vegetables generates a satiety sensation and favors the reduction of total calories consumed. Quinoa leaves can be consumed raw when they are ripe or steam cooked; they retain most of their vitamins and minerals. The FAO considers quinoa to be the “perfect food”, and it is not only used in common diets, but it is also suitable for the unique diets of those that are vegetarian or high-performance athletes as well as those with celiac disease and diabetes. The objective of this work was to determine the nutritional value of quinoa leaves. For every test, dried and powdered quinoa leaves were used, and the following parameters were determined: total polyphenols, total flavonoids, proteins, carbohydrates, reducing sugars, water content, ash content, and raw fiber, and the flavonoids were determined by HPLC. The results obtained for the polyphenols were 131.8 ± 10.3 mg 100 g-1 and 62.07 ± 5.1 mg 100 g-1 for flavonoids, and the main compounds were gallic acid, kaempferol and catechin. The content of proteins was 11.8 ± 0.6%, the carbohydrates was 18.3 ± 0.9, the reducing sugars were 3.2 ± 0.27%, the water content was 2.8 ± 0.9%, the ash content was 1.4 ± 0.14%, and the raw fiber content was 43.7 ± 3.9%. Based on the nutritional profile and the content of polyphenols and total flavonoids, quinoa leaves can be considered an alternative for human consumption because they offer interesting potential in nutrients and antioxidant capacity, which is a dietary requirement

Nutrimental Content and Functional Properties of Quinoa Flour from Chile and Mexico

Knowledge related to the genetic improvement of quinoa has been increasing in recent years, demonstrating an effective advance in obtaining morphological characteristics meant to achieve uniformity in the quantity and quality of the production obtained in the field. For this research, quinoa flour harvested in Mexico and Chile, the latter of which was genetically modified, was obtained and characterized. Next, the determination of moisture, fats, fiber, carbohydrates, acidity, ash, proteins, polyphenols, and flavonoids was performed. Functional properties were also evaluated, and a microbiological count was made. No differences were observed in the odor and color of the flours, nor was there a change in moisture during 6 months of storage. The initial percentages of acidity, fats, proteins and ashes were higher in Chilean flour (2.25, 10.99, 10.69 and 3.54%, respectively), while flour from Mexico presented 1.75, 7.64, 8.4 and 3.17%, respectively. Regarding raw fiber and carbohydrates, the results obtained were lower for Chilean flour (2.78 and 59.78%, respectively), while Mexican flour showed 4.08 and 66.67%, respectively. The content of flavonoids and polyphenols in Chilean flour were higher than those of Mexico. The results obtained reveal that the nutritional content of Chilean quinoa flour was better than that of Mexico. The growth of molds and yeasts was observed in the 6th month for the Mexican flour; however, the values did not exceed the limits of the OMN (Official Mexican Norm) 247

Alterations of blood chemistry, hepatic and renal function, and blood cytometry in acrylamide-treated rats

Acrylamide is a vinyl monomer that is widely used for the synthesis of polyacrylamides, the treatment of drinking water, and as an additive in cosmetics. Acrylamide is also produced during the thermal processing of carbohydrate-rich foods. Although the potential toxic effects of acrylamide have been reported, few studies have evaluated biochemical parameters in blood. The present study investigated alterations of blood chemistry, hepatic function, and blood cytometry in acrylamide-treated rats. Thirty-two male Wistar rats were assigned to four experimental groups (n = 8/group): one control group received 0.3 ml of vehicle (saline solution), and the other three groups received acrylamide (25, 50, and 75 mg/kg, i.p., for 14 days). At the end of treatment, blood samples were collected to obtain serum, which was then processed using a Vitros250 device. For blood cytometry, the samples were processed in a Sysmex analyzer. The blood chemistry results showed that urea nitrogen, urea, and creatinine were elevated in the acrylamide-treated groups. Tests of hepatic function showed that total and direct bilirubins, transaminases, and alkaline phosphatase were also elevated compared with vehicle, whereas the levels of total proteins and albumin decreased. Blood cytometry showed that the levels of erythrocytes, hemoglobin, hematocrit, leukocytes, and platelets and mean cell volume decreased in the acrylamide-treated groups compared with vehicle. Overall, the present findings indicate that acrylamide causes deleterious effects on renal and hepatic physiology, producing dose-dependent alterations of blood chemistry and cytometry parameters in male Wistar rats. Keywords: Acrylamide, Blood cytometry, Blood chemistry, Hepatic functio

Word Association Norms for Healthy Older Adults

database of word association and sociodemographic data of older adult

Estrategias de afrontamiento en adultos con diabetes mellitus tipo 2 de una comunidad de Tamaulipas, México

Objetivo: Identificar las estrategias de afrontamiento de un grupo de adultos con diabetes mellitus tipo 2 de una comunidad urbana de Tamaulipas. Metodología: Estudio descriptivo-trasversal, llevado a cabo en 215 adultos portadores de diabetes mellitus tipo2. Se aplicó una cedula de datos sociodemográficos y el Inventario de Estrategias de Afrontamiento (CSI). Los datos se procesaron con el paquete estadístico SPSS versión 21. Investigación sustentada bajo las normas de la Ley General de Salud en Materia de Investigación en México. Resultados: Prevaleciendo la participación del sexo femenino con un 72.09%. El 58.13%% poseen adecuadas estrategias de afrontamiento, el 35.37% poseen buenas estrategias de afrontamiento, el resto malas estrategias de afrontamiento. Por dominios el 43.7% presentaron adecuada y buena resolución de problemas, el 66.0% presento baja autocritica. 72.5% tuvo adecuada expresión emocional. El 79.0% presento pensamientos desiderativos, 55.3% tiene buen apoyo social, 32.0% presento baja reestructuración cognitiva. El 45.1% y 33.9% presento insuficiente y baja evitación de problemas respectivamente. Y el 66.0% y 30.6% tenía negativa y moderada retirada social respectivamente. Conclusiones: Las estrategias de afrontamiento se deben considerar como aquellas demandas tanto físicas como mentales que hay que poner en práctica para favorecer la calidad de vida de las personas que padecen una enfermedad crónica, ya que es una parte decisiva para avanzar o estancarse en el manejo de la enfermedad la cual no es transitoria sino permanente y al no tratarla adecuadamente provoca complicaciones de diferente índole, afectando todas las esferas de la persona

Pregestational Exposure to T. gondii Produces Maternal Antibodies That Recognize Fetal Brain Mimotopes and Induces Neurochemical and Behavioral Dysfunction in the Offspring

The activation of the maternal immune system by a prenatal infection is considered a risk factor for developing psychiatric disorders in the offspring. Toxoplasma gondii is one of the pathogenic infections associated with schizophrenia. Recent studies have shown an association between high levels of IgG anti-T. gondii from mothers and their neonates, with a higher risk of developing schizophrenia. The absence of the parasite and the levels of IgGs found in the early stages of life suggest a transplacental transfer of the anti-T. gondii IgG antibodies, which could bind fetal brain structures by molecular mimicry and induce alterations in neurodevelopment. This study aimed to determine the maternal pathogenic antibodies formation that led to behavioral impairment on the progeny of rats immunized with T. gondii. Female rats were immunized prior to gestation with T. gondii lysate (3 times/once per week). The anti-T. gondii IgG levels were determined in the serum of pregestational exposed females’ previous mating. After this, locomotor activity, cognitive and social tests were performed. Cortical neurotransmitter levels for dopamine and glutamate were evaluated at 60 PND in the progeny of rats immunized before gestation (Pregestational group). The maternal pathogenic antibodies were evidenced by their binding to fetal brain mimotopes in the Pregestational group and the reactivity of the serum containing anti-T. gondii IgG was tested in control fetal brains (non-immunized). These results showed that the Pregestational group presented impairment in short and long-term memory, hypoactivity and alteration in social behavior, which was also associated with a decrease in cortical glutamate and dopamine levels. We also found the IgG antibodies bound to brain mimotopes in fetuses from females immunized with T. gondii, as well as observing a strong reactivity of the serum females immunized for fetal brain structures of fetuses from unimmunized mothers. Our results suggest that the exposure to T. gondii before gestation produced maternal pathogenic antibodies that can recognize fetal brain mimotopes and lead to neurochemical and behavioral alterations in the offspring