Infectious Mononucleosis: A Case Report With Unusual Features and Abnormal Laboratory Findings

Despite the widespread Epstein-Barr virus (EBV) infections, we continue to see new reports with strange and unusual manifestations of the infection, which raises the question of how well we understand this pathogen. The age of contracting the infection is increasing in developed countries, which is changing the clinical presentation of those who get infected during their adolescence or early adulthood. In these stages, liver involvement is more prominent, and other physical symptoms are less apparent. Therefore, an update on infectious mononucleosis (IM) variable manifestation is required to make healthcare providers aware of this shift. This case stands as an example of the new shift as a patient scheduled for elective surgery suddenly presented with subclinical hepatitis caused by primary EBV infection. Our patient presented with few physical symptoms but had a classical picture of EBV-induced hepatitis on blood analysis. The diagnosis was missed by many physicians due to the varied presentations of IM. This case corresponds to the new evidence that suggests that hepatic involvement is one of the most prominent manifestation in the adult population with primary EBV infection

Identification of proteolytic products as indicators of quality in ground and whole meat

This study was devoted to the identification of specific peptides and proteins which can serve as indicators of spoilage in meat. Samples of ground and whole meat were subjected to storage at 4C, at intervals of 0, 2, 4, 8, 12 and 16 days, samples were analyzed for pH and microbial populations and subjected to extraction and separation of individual sarcoplasmic and myofibrillar peptides and proteins by SDS (sodium dodecyl sulfate) and native electrophoresis and by RP-HPLC. Sarcoplasmic protein and peptide fractions from RP-HPLC were collected and identified by (electrospray ionization mass spectrometry) ESI-MS. The results demonstrated substantial differences in microbial population and pH between ground and whole meat during storage. Separation by SDS-electro-phoresis showed substantial changes in myofibrillar protein of ground meat after 12 days and of whole meat after 16 days of storage. Separation and identification of sarcoplasmic proteins by SDS-electrophoresis and by RP-HPLC followed by ESI-MS revealed the disappearance of a protein fraction band of MW 36 kDa after 8 days of storage in ground and whole meat

Effect of palm bunch ash treatment on remediation and growth performance of Zea mays in crude oil polluted soil

The effect of polluted hydrocarbon (PHC) soil altering the fertility of the soil for effective plant growth yield is a major concern. This study examines the use of oil palm bunch ash as biostimulation technique for bioremediation of PHC soils. Under strict compliance of oil treatment of 10g, 20g, 30g, 40g, 50g, and 60g with oil palm bunch ash on soil samples of 2kg weighed surface soil of 0-20cm polluted and non-polluted sites were collected randomly into perforated planting bags. Various results of residual and cumulative effect on treated soil of oil palm bunch ash enhances the improvement of Zea mays growth performance at 7WAP (7 weeks after planting) after eight months post-treated soils. The residual result shows that optimum treatment favoured 40g/2kg soil with plant emergence ( 41.67% ), plant height ( 22.77cm) and dry matter ( 0.7235g ), while cumulative treatment revealed 30g/2kg treatment as optimum with plant emergence ( 91.67% ), plant height ( 24.40 cm) and dry matter ( 0.8202g ). No doubt, this study of treating PHC soil with oil palm bunch ash at the above mentioned treatment levels improved soil performance for plant growth by reducing the hydrophobic nature of soils which resulted to improvement in the availability of water, oxygen and mineralization of soils. Key words: Biostimulation, Bioremediation, Residual, Cumulative, Plant Performance.

PREDICTING SOCIAL NETWORK ADDICTION USING VARIANT SIGMOID TRANSFER FEED-FORWARD NEURAL NETWORKS (FNN-SNA)

Researchers have reflected on personal traits that may predict Social Networking Sites (SNS) addiction. However, most of the researchers involved in the findings of personality traits predictor for social networking addiction either postulate or based their conclusions on analytical tools. Moreso, a review of the literature reveals that the prediction of social networking addiction using classifiers have not been well researched. We examined the prediction of SNS addiction from a well-structured questionnaire consisting of sixteen (16) personality traits. The questionnaire was administered on the google form with a response rate of 95% out of the 102-sample size. Additionally, a three (3) variant sigmoid transfer feed- forward neural networks was developed for the prediction of SNS addiction. Result indicated that pertinence (β = 0.251, p  0.01) was the most powerful predictor of social networking addiction in general and less obscurity addiction (β = 0.244, p  0.01). Experimental results also showed that the developed classifier correctly predict SNS addiction with 98% accuracy compared to similar classifiers.     &nbsp

Medullary carcinoma of the breast: Role of contrast-enhanced MRI in the diagnosis of multiple breast lesions

Medullary carcinoma is a rare breast carcinoma with a syncytial growth pattern and high-grade cytology. It can be difficult to diagnose and may be missed on conventional imaging as the findings may overlap with benign lesions i.e. fibroadenomas. The authors report a case of a 25-year-old female who presented with multifocal breast lumps diagnosed with medullary carcinoma and fibroadenomas. Imaging and pathological correlation with contrast-enhanced MRI are presented in the diagnosis of these lesions

Molecular identification and prevalence of Mycobacterium tuberculosis complex amongst people living with HIV in Osun state, Nigeria.

Human immunodeficiency virus (HIV) infection has created a special niche for Mycobacterium tuberculosis complex in humans as a result of the defect/reduction in cell mediated immunity. M. tuberculosis still responsible for most cases of death due to infectious diseases after HIV. In this study, prevalence of M. tuberculosis was determined in people living with HIV in Osun state of Nigeria with identification of culture positive isolates by polymerase chain reaction. A total of 160 samples were collected from people living with HIV with mean age of 36.8 years old of age (Median -34; age range 16 – 68; 95% confidence interval – 2.49) after seeking ethical approval from the Ministry of Health, Osun State. The result of the microscopy by ZN stain showed that 40 (25%) of the 160 samples were positive for acid fast bacilli while culture on Lowenstein-Jensen (LJ) medium revealed that 30 (18.75%) of the samples processed, grew organism that conformed to the characteristics of M. tuberculosis complex. Polymerase chain reaction for IS6110 was used to confirm the identity of the colonies on LJ slope as M. tuberculosis complex while the PCR for 260 bp of Rv1255c was used in identifying M. tuberculosis. M. tuberculosis represented 92% of the M. tuberculosis complex. The prevalence of M. tuberculosis among people living with HIV was found to be 15% after PCR identification. The effects of socio-demographic factors on the prevalence of TB were analysed. Occupation was found to be associated with the proportional distribution of TB in people living with HIV (X2 = 14.85; p < 0.05). The study concluded that PCR should be integrated into the schema for identification of tuberculosis in reference laboratories in developing countries.Key words: Molecular identification, Polymerase chain reaction, Mycobacterium tuberculosis complex; Mycobacterium tuberculosis, Prevalence, HIV, Nigeri