Compliant walker

A compliant walker is provided for humans having limited use of their legs and lower back. It includes an upright wheel frame which at least partially surrounds an upright user wearing a partial body harness. It is attached to the frame by means of cable compliant apparatus consisting of sets of cable segments and angle bracket members connected between opposite side members of the frame and adjacent side portions of the harness. Novelty is believed to exist in the combination of a wheeled frame including a side support structure, a body harness, and compliance means connecting the body harness to the side support structure for flexibility holding and supporting a person in a substantially upright position when the user sags in the frame when taking weight off the lower extremities

Beauty in worship : a paradigm incorporating philosophical and theological attributes of beauty in assessing worship

https://place.asburyseminary.edu/ecommonsatsdissertations/1242/thumbnail.jp

The Effects of Psychotrophic Contamination and the Addition of Sodium-Citrate on Major Chemical Components and Flavor of Buttermilk.

The main objective of this research was to determine what effect, if any, post-pasteurization contamination and/or sodium citrate would have on major chemical components and flavor of buttermilk. Also, it was of interest to establish chemical profiles of good versus bad buttermilk and to gain information which would aid in the prediction of buttermilk flavor. The research was divided into two parts. In Part I buttermilk was artificially inoculated with psychrotrophs (Pseudomonas fluorescens P27) at time of bottling. Part II examined the effect of psychrotrophic contamination at time of set with a lactic culture. Treatments consisted of buttermilk, both with and without added sodium citrate (.15%), and three inocula of psychrotrophs (0/ml, 10(\u274)/ml and 10(\u276)/ml). After processing, buttermilk was stored at 7(DEGREES)C in plastic 3.78 1 containers and sampled at 0, 3, 5, 10, 15 and 20 d. Volatile organics (acetaldehyde, acetone, ethanol and diacetyl) were determined by gas chromotography with headspace sampling followed by organic acid (orotic, lactic, acetic and propionic) analysis by high performance liquid chromotography. Microbial parameters examined were total lactic streptococci, gram negatives and citrate fermenting bacteria. Flavor evaluations were performed by a three member trained taste panel. The Hull test was used to determine proteolysis. Data revealed no significant changes in volatile organics or organic acids as a result of psychrotrophic contamination at time of bottling. Increases in acetaldehyde and decreases in acetone were observed in buttermilk inoculated with psychrotrophs at time of set with a lactic culture. The addition of sodium citrate to milk prior to fermentation yielded higher levels of diacetyl, acetone, lactic acid, acetic acid and propionic acid. Higher concentrations of these components resulted in a definite improvement in buttermilk flavor. Among the chemical components studied, acetone was that which was most often related to flavor. In addition, regression equations were established which laid a foundation for further study in the area of flavor prediction

Fatty acid required for glucose-induced change in beta cell plasma membrane potential leading to insulin secretion

The pancreatic β−cell secretes insulin through a combination of triggering and amplification pathways in response to glucose. Glucose metabolism is known to increase intracellular calcium and trigger insulin secretion from the β−cell while fatty acid (FA), an essential component of glucose stimulated insulin secretion (GSIS), is known to amplify secretion through varied mechanisms. Orlistat, a lipase inhibitor, blocks GSIS although the mechanism has not been clearly elucidated. We show that orlistat can also inhibit basal insulin secretion. FA can prevent/reverse orlistat-induced inhibition of secretion but fails to amplify GSIS after orlistat treatment. Here we test the hypothesis that FA is required to maintain normal plasma membrane potential and calcium influx in the β−cell. Clonal pancreatic β−cells (INS-1 832/13) were cultured in RPMI media containing 11 mM glucose and 10% FBS. Insulin secretion was measured over 2 hours with and without FA and orlistat (200 µM) using homogeneous time resolved fluorescence insulin assay (HTRF, Cisbio) and reported as ng/million cells. Intracellular calcium was measured in single cells using fura-2 AM. Single cell membrane potential was measured with virally expressed ARC Lite protein (Montana molecular). High glucose (8 mM) stimulated insulin secretion at least 3-fold over basal glucose (2 mM) and addition of FA enhanced GSIS. Orlistat almost completely abolished GSIS. This inhibition was mostly prevented in the presence of FA. Orlistat blocked calcium influx required for triggering insulin release while addition of FA recovered normal calcium homeostasis. The monoacylglycerol lipase inhibitor JZL 184 reduced both calcium influx and the increase in plasma membrane potential induced by KCl. FA recovered plasma membrane potential inhibited by JZL 184. Our results suggest that reducing β−cell intracellular FA availability by lipase inhibition blocks GSIS by preventing the glucose-induced rise in plasma membrane potential required to induce β−cell calcium influx through voltage dependent calcium channels (VDCC). FA is thus required to maintain normal nutrient metabolic coupling to insulin secretion. Whether the effect of FA to modulate plasma membrane potential plays a role in β−cell insulin hypersecretion resulting from excess nutrients requires further investigation

An item analysis of Wechsler-Bellevue intelligence scale form I subtests

The purpose of this study was to: (1) analyze the value of subtest items in discriminating between bright, average, dull normal, borderline, and mentally defective groups; and (2) indicate the rank order of difficulty in the total population for each item

Prague, Nebraska: A Traditional Village in Modern Society

The subject of this thesis is life satisfaction as it relates to older persons living in small, rural communities. Particularly, this study is concerned with potential low life satisfaction and loneliness due to limited interaction and increasing social isolation resulting from the decline of rural communities. The focus of the study, Prague, Nebraska, is a village that continues to survive as a social system in which community members, especially older residents, interact and live in a familiar, ongoing social environment. The study looks at the social processes of this small, rural community that has over the years redefined and solved the problems of subsistence, social relations, and social identification within its locality. This has enabled the community to persist. A presentation of the social psychology of the community shows that the traditional nature of the peasant population who settled the community has been maintained through ritual and symbolism. Central to these peasant traditions has been commitment to the survivability of the community. A collective identity has evolved through a process of ritual and symbolism allowing older residents to maintain social relations and interactions resulting in positive effects on life satisfaction. Older persons are not isolated in Prague, but are an important part of this intergenerational community

A Separate Asset Class for Cryptocurrency

The purpose of this qualitative study was to research the need for a separate asset class for cryptocurrency. The researcher found a lack of research on this topic and conducted research that provides more information on the topic than is currently in existence. The researcher examined the effects of classification and lack of classification of cryptocurrency as an asset class. This research provided a greater understanding of how cryptocurrency is working without a separate asset classification and added to the current research on the topic. The researcher interviewed multiple people, all with various forms of involvement with cryptocurrency. The interview participants were all pro cryptocurrency and believed in the future of cryptocurrency. The research participants were asked questions about the different asset classes, opinions on the need for a separate asset class for cryptocurrency, regulation, the level of government’s involvement, and the governmental agencies that would be involved in the cryptocurrency regulation. The researcher and the interviewees identified different thoughts on the need for separate asset classification for cryptocurrency and the level of importance for this action. Additionally, the researcher made multiple recommendations for action by the government and cryptocurrency enthusiasts. Due to cryptocurrency’s constant evolvement, the researcher supported the need for continuous research on cryptocurrency, potential classification, and regulation