The Molly Hootch Schools After 40 Years: Successes, Failures, and Opportunities

This quantitative study was designed to understand the relationship between the variables of student attendance, educator experience and turnover, and student achievement at the Molly Hootch schools in rural Alaska, to better understand the current state of achievement according to data from 2002–2019, collected from the Alaska Department of Education and Early Development (AKDEED) database. Data revealed that Molly Hootch school attendance was at 90% and that proficiency among students dropped from 40% to 15% during the years under review. The drop in proficiency during a time period where attendance level was strong leads to further qualitative exploration of the causes of the phenomenon

Shadow IT Use, Outcome Effects, and Subjective Performance Evaluation

Abstract: The use of shadow IT (information technology systems not sanctioned or monitored by a company’s IT department) may be seen as either a form of organizational misbehavior or proactive and creative problem-solving. We examine whether these differing possible perceptions have implications for the subjective evaluation of subordinate performance. In our experiment, participants choose whether to award a bonus to an employee when different IT systems are used (normal vs. shadow IT) across different outcome levels (high vs. low outcomes). We find that employees using shadow IT are less likely to receive the bonus in both high and low outcome conditions relative to employees using the normal IT system. Our results suggest that shadow IT usage is more likely to be viewed as organizational misbehavior and to cast a negative light on employee performance

An Investigation of Social Interaction Between Severely Autistic Adolescents and Mildly Handicapped Peers

The purpose of this study was to examine social interactions between severely autistic adolescents and mildly handicapped peers in a segregated special education setting. This was accomplished by determining (1) the frequency of reciprocal social interactions between severely autistic adolescents and mildly handicapped peers; (2) the types of social behaviors most frequently exhibited by severely autistic adolescents; (3) the levels of initiations and responses made by severely autistic adolescents and mildly handicapped peers; and ( 4) the post-intervention social behaviors of the severely autistic adolescents. Three severely autistic adolescents were exposed to a peer social initiation intervention employed by three mildly handicapped peers over a period of three months. The peer social initiation intervention was used to increase social interaction between the autistic students and their mildly handicapped peers.The research design was a multiple baseline across subjects evaluation. It was used to assess the effects of the peer intervention on each subjects' reciprocal social interactions and specific social behaviors. The independent variable was exposure to a peer social initiation intervention designed to increase social interaction behaviors. The primary dependent variable was reciprocal social interaction, which was defined as one student's positive social initiation followed by another student's positive response within 3 seconds. Results of the study were: 1. The peer social initiation intervention increased the percentage of intervals in which reciprocal interactions occurred between severely autistic students and mildly handicapped peers. 2. The peer social initiation intervention increased other vocal/verbal and other motor/gestural behaviors for the severely autistic students. 3. The levels of social responding by severely autistic adolescents increased as a result of the peer social initiation intervention. 4. Increases in reciprocal social interactions for two severely autistic adolescents generalized to a free play setting with trained and untrained peers

The Effects of Different Types of Internal Controls on Self-Control

One reason companies implement internal controls is to reduce the likelihood of unethical behavior. Yet, ego depletion theory suggests that some controls may cause reductions in employees’ self-control, which could undermine the ability of controls to reduce unethical behavior. We examine whether various types of controls impact self-control and ethical judgments. Our results show that contrary to the ego depletion hypothesis, we find no significant relation between self-control and internal controls. Furthermore, we find that controls have no effect on ethical judgments or ethical ideology. Thus, our results suggest that internal controls do not differentially impact self-control and ethical decision-making

Shadow IT Use, Outcome Effects, and Subjective Performance Evaluation

Using shadow IT may be seen as either a form of organizational misbehavior or proactive and creative problem-solving. These perceptions have implications for the subjective evaluation of subordinate performance. In our experiment, participants choose whether to award a bonus to an employee when different IT systems are used across different outcome levels. We find that employees using shadow IT are less likely to receive the bonus in both high and low outcome conditions relative to employees using the normal IT system, suggesting that managers consider shadow IT usage an organizational misbehavior which casts a negative light on employee performance

In Vivo Cross-Priming of MHC Class I–Restricted Antigens Requires the TAP Transporter

AbstractRecent in vitro evidence suggests two alternative mechanisms by which bone marrow–derived APCs may process exogenous antigens for presentation to CTL in vivo, a phenomenon termed cross-priming. Although in vitro studies have suggested that both TAP-dependent and TAP-independent pathways exist, we have now demonstrated an absolute requirement for a functional TAP for cross-priming to occur in vivo. Bone marrow chimeras reconstituted with marrow from TAP-defective donors develop functional CD8+ CTL, but have APCs with disrupted TAP function. In such chimeras, in vivo priming of naive CTL was observed when antigen was targeted to the ER in a TAP-independent fashion, but cross-priming could not be demonstrated. These results support the TAP-dependent mechanism of cross-priming

IPHAS and the symbiotic stars. I. Selection method and first discoveries

The study of symbiotic stars is essential to understand important aspects of stellar evolution in interacting binaries. Their observed population in the Galaxy is however poorly known, and is one to three orders of magnitudes smaller than the predicted population size. IPHAS, the INT Photometric Halpha survey of the Northern Galactic plane, gives us the opportunity to make a systematic, complete search for symbiotic stars in a magnitude-limited volume, and discover a significant number of new systems. A method of selecting candidate symbiotic stars by combining IPHAS and near-IR (2MASS) colours is presented. It allows us to distinguish symbiotic binaries from normal stars and most of the other types of Halpha emission line stars in the Galaxy. The only exception are T Tauri stars, which can however be recognized because of their concentration in star forming regions. Using these selection criteria, we discuss the classification of a list of 4338 IPHAS stars with Halpha in emission. 1500 to 2000 of them are likely to be Be stars. Among the remaining objects, 1183 fulfill our photometric constraints to be considered candidate symbiotic stars. The spectroscopic confirmation of three of these objects, which are the first new symbiotic stars discovered by IPHAS, proves the potential of the survey and selection method.Comment: Accepted for publication on Astronomy and Astrophysics. 12 pages, 8 figure

An Event Study Analysis of Too-Big-to-Fail After the Dodd-Frank Act: Who is Too Big to Fail?

One feature of the Dodd-Frank Act is the elimination of too-big-to-fail (TBTF) banks. TBTF is a government guarantee of large banks that has been shown to increase the value of these banks, so removing the guarantee should result in a price decline of TBTF bank stock. Using event study methods, we find very limited reaction to the process of eliminating TBTF. Specifically, there is limited reaction among the largest banks and banks receiving special attention, such as Systemically Important Financial Institutions (SIFI) banks. Instead, smaller banks not receiving special attention show some evidence of negative returns with the elimination of TBTF

Kalirin Decreases Bone Mass Through Effects in Both Osteoclasts and Osteoblasts

poster abstractBone homeostasis is maintained by the balance between osteoclasts which degrade bone and osteoblasts, which form new bone. When the activity of either of these cells is dysregulated, bone loss can ensue, leading to osteoporosis, a disease characterized by low bone mass and an increase in bone fragility and risk of fracture. The activity of osteoclasts and osteoblasts is regulated by local and systemic factors, as well as by key signaling proteins expressed in these cells. Kalirin is a novel GTP-exchange factor protein that plays a role in signaling pathways leading to cytoskeletal remodeling and dendritic spine formation in neurons, but its function in other cells is unknown. Western blotting and real time PCR confirmed that Kalirin is expressed in osteoclasts and osteoblasts, suggesting it may play a role in regulating bone cell function and bone mass. We used micro-CT to examine the bone phenotype of 14 week old female mice lacking Kalirin in all tissues (Kal-KO). Kal-KO mice exhibited a 40% lower trabecular bone volume in the distal femur compared to wild-type (WT) mice (n=9/group, p<0.05). We next quantified osteoclasts in histological sections by counting multinucleated cells expressing tartrate-resistant acid phosphatase (TRAP), a marker of mature osteoclasts. We found 48% higher osteoclast surface/bone surface in trabecular bone of Kal-KO mice, compared to WT mice (n=6/group, p<0.05). Osteoclast differentiation is controlled by osteoblasts, which secrete receptor activator of NF-kB ligand (RANKL), macrophage colony stimulating factor (MCSF) and osteoprotegerin (OPG), a decoy receptor for RANKL. We examined if Kalirin could regulate osteoclast differentiation in vitro. Osteoclasts were generated from the bone marrow of WT or Kal-KO mice by incubation with RANKL and MCSF for 7 days, and TRAP+ multinucleated cells were counted. Consistent with our in vivo studies, osteoclast number was significantly higher in cultures from Kal-KO mice, compared to WT mice. We next examined if Kalirin altered the ratio of secreted RANKL and OPG secreted by osteoblasts. Osteoblasts were generated from the calvaria of 2 day old neonates and the level of secreted RANKL and OPG in conditioned media was quantified by ELISA. Consistent with increased osteoclast differentiation, we found a higher RANKL/OPG ratio in conditioned media from Kal-KO osteoblasts, compared to WT cells. These data confirm a role for Kalirin in the regulation of trabecular bone mass through effects in both osteoclasts and osteoblasts