Instructional materials to support an integrated social studies theme on families for primary students in a multi-age classroom

The purpose of this project was to assemble a collection of instructional materials to be used in my primary multi-age classroom in Cedar Rapids, Iowa. The organizing objectives were taken from the district\u27s social studies theme for Families and the district\u27s objectives for integrated language arts. The goal of the project was to coordinate a group of quality materials and suggest response activities to support using an integrated curriculum approach, specifically a literature-based social studies theme

Continuous manganese delivery via osmotic pumps for manganese-enhanced mouse MRI does not impair spatial learning but leads to skin ulceration

Manganese-enhanced magnetic resonance imaging (MEMRI) is a widely used technique in rodent neuroimaging studies. Traditionally, Mn2+ is delivered to animals via a systemic injection; however, this can lead to toxic effects at high doses. Recent studies have shown that subcutaneously implanted mini-osmotic pumps can be used to continuously deliver manganese chloride (MnCl2), and that they produce satisfactory contrast while circumventing many of the toxic side effects. However, neither the time-course of signal enhancement nor the effect of continuous Mn2+ delivery on behaviour, particularly learning and memory, have been well-characterized. Here, we investigated the effect of MnCl2 dose and route of administration on a) spatial learning in the Morris Water Maze and b) tissue signal enhancement in the mouse brain. Even as early as 3 days after pump implantation, infusion of 25–50 mg/kg/day MnCl2 via osmotic pump produced signal enhancement as good as or better than that achieved 24 h after a single 50 mg/kg intraperitoneal injection. Neither route of delivery nor MnCl2 dose adversely affected spatial learning and memory on the water maze. However, especially at higher doses, mice receiving MnCl2 via osmotic pumps developed skin ulceration which limited the imaging window. With these findings, we provide recommendations for route and dose of MnCl2 to use for different study designs

Fluid-Structural Coupling Effects on the Dynamics of Mistuned Bladed Disks

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/77177/1/AIAA-23809-593.pd

High‐Performance Zinc Tin Oxide TFTs with Active Layers Deposited by Atomic Layer Deposition

New deposition techniques for amorphous oxide semiconductors compatible with silicon back end of line manufacturing are needed for 3D monolithic integration of thin‐film electronics. Here, three atomic layer deposition (ALD) processes are compared for the fabrication of amorphous zinc tin oxide (ZTO) channels in bottom‐gate, top‐contact n‐channel transistors. As‐deposited ZTO films, made by ALD at 150–200 °C, exhibit semiconducting, enhancement‐mode behavior with electron mobility as high as 13 cm2 V−1 s−1, due to a low density of oxygen‐related defects. ZTO deposited at 200 °C using a hybrid thermal‐plasma ALD process with an optimal tin composition of 21%, post‐annealed at 400 °C, shows excellent performance with a record high mobility of 22.1 cm2 V–1 s–1 and a subthreshold slope of 0.29 V dec–1. Increasing the deposition temperature and performing post‐deposition anneals at 300–500 °C lead to an increased density of the X‐ray amorphous ZTO film, improving its electrical properties. By optimizing the ZTO active layer thickness and using a high‐k gate insulator (ALD Al2O3), the transistor switching voltage is lowered, enabling electrical compatibility with silicon integrated circuits. This work opens the possibility of monolithic integration of ALD ZTO‐based thin‐film electronics with silicon integrated circuits or onto large‐area flexible substrates.Three atomic layer deposition (ALD) processes are investigated for the deposition of zinc tin oxide (ZTO) as the active layer in thin‐film transistors (TFTs). With a low density of oxygen vacancies, as‐deposited films exhibit semiconducting, enhancement‐mode behavior. Post‐deposition anneals result in increased film density and record high electron mobility for ALD ZTO TFTs using process temperatures within the back‐end‐of‐line thermal budget.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/156226/3/aelm202000195-sup-0001-SuppMat.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/156226/2/aelm202000195.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/156226/1/aelm202000195_am.pd

Francisella tularensis novicida proteomic and transcriptomic data integration and annotation based on semantic web technologies

This paper summarises the lessons and experiences gained from a case study of the application of semantic web technologies to the integration of data from the bacterial species Francisella tularensis novicida (Fn). Fn data sources are disparate and heterogeneous, as multiple laboratories across the world, using multiple technologies, perform experiments to understand the mechanism of virulence. It is hard to integrate these data sources in a flexible manner that allows new experimental data to be added and compared when required

A new damping modelling approach and its application in thin wall machining

In this paper, a new approach to modelling the damping parameters and its application in thin wall machining is presented. The approach to predicting the damping parameters proposed in this paper eliminates the need for experiments otherwise used to acquire these parameters. The damping model proposed was compared with available damping models and experimental results. A finite element analysis and Fourier transform approach has been used to obtain frequency response function (FRF) needed for stability lobes prediction. Several predicted stable regions using both experimental and numerical FRF’s for various examples gave a good comparison.Engineering and Physical Sciences Research Counci