Meme hisse senetlerinin borsa üzerindeki etkiii: Gamestop mania

WallStreetBets forum on the popular Reddit platform has drawn the attention of not merely financial market participants, but also policymakers as retail investors gathering in the forum circulate tickers of certain securities and jump on the bandwagon in an attempt to push up the prices. This study examines what transpired in January 2021 trading frenzy in GME which became a meme stock and the star of Redditors and other mania-influenced stocks igniting a battle between retail investors gathering in the forum and Wall Street hedge funds. The study deploys a VAR(p)-process and its structural analysis tools to examine the impact of the trading frenzy by empirically investigating whether an intertwined association significantly differs from the pre-saga time horizon by focusing on the most popular stocks among retail investors during the peak of the mania; GameStop (GME), AMC Entertainment Holdings Inc. (AMC), Naked Brand Group (NAKD) and Koss Corporation (KOSS) and the spillovers to the broad market…Popüler Reddit platformundaki WallStreetBets forumu, yalnızca finansal piyasa katılımcılarının değil, aynı zamanda forumda toplanan perakende yatırımcılar olarak politika yapıcıların da dikkatini çekti, belirli menkul kıymetleri dolaştırıyor ve fiyatları yükseltmek için çoğunluğa atlıyor. Bu çalışma, bir meme hissesi ve Redditors'un yıldızı haline gelen GME'de Ocak 2021 ticaret çılgınlığında ve forumda toplanan perakende yatırımcılar ile Wall Street riskten korunma fonları arasında bir savaşı ateşleyen diğer manyadan etkilenen hisse senetlerini incelemektedir. Çalışma, perakende yatırımcılar arasında en popüler hisse senetlerine odaklanarak iç içe geçmiş bir ilişkinin destan öncesi zaman ufkundan önemli ölçüde farklı olup olmadığını ampirik olarak araştırarak ticaret çılgınlığının etkisini incelemek için bir VAR(p) süreci ve yapısal analiz araçlarını kullanıyor. Maninin zirvesi; GameStop (GME), AMC Entertainment Holdings Inc (AMC), Naked Brand Group (NAKD) and Koss Corporation (KOSS) ve geniş pazara yayılmaları

Illuminance and ultra violet emissions radiated from white compact fluorescent lamps

During recent years, white compact fluorescent lamps (WCFLs) have played a key role in energy efficient campaigns worldwide. As the use of WCFLs becomes increasingly widespread so also increases the concerns relating to their mercury content and the associated hazards. While the risk associated with individual WCFLs is generally concerned negligible, the cumulative impact of millions of WCFLs does however becomes a more significant issue and could represent a potential risk to the environment. The present study aimed to focus on the most useable lamps in the Egyptian markets; white compact fluorescent lamps (WCFLs) and to evaluate relationships between UV emissions radiated and illuminance compact fluorescent lamps (WCFLs). Various parameters such as ultra violet irradiance (UVA), ratio of UVA irradiance to electrical power (η) and ratio of UVA power to luminous flux (K), for two groups of CFLs are studied to dedicate their performance. A set up based on NIS-Spectroradiometer ocean optics HR 2000 has been used for measuring the spectral power distribution white WCFLs with different Egyptian market. Second set up for NIS-UVA silicon detector for absolute irradiance measurements and relative spectral power distribution based on Spectroradiometer are used. The absolute irradiance in W/m2 in UVA region of the lamps and their accompanied standard uncertainty are evaluated. Third set up based on NIS Luxmeter are used for measuring illuminance for these lamps. For all two groups under study, K parameter remains less than the safe limit for human health. Elios 32 watt WCFLs have smaller ratio (η) than Tiger 26 watt WCFLs. So, we recommended using Elios 32 watt WCFLs than Tiger 26 watt WCFLs at short distance in table lamps or other application and the distance more than 0.5 m. Uncertainty model includes all parameters accompanied with the measurements are calculated

Exploring the challenges to using telecardiology as perceived by pre-hospital emergency care personnel: a qualitative study

Abstract Background Today, using the medical technology of telecardiology, as part of advanced medical services, plays an essential role in providing care to cardiac patients in life-threatening conditions who need emergency care. However, pre-hospital emergency care personnel are faced with certain challenges in using telecardiology, with adverse effects on their performance. Therefore, the present study aimed to investigate the challenges to using telecardiology as viewed by pre-hospital emergency care personnel in Southern Iran. Methods The present study is a qualitative work of research with a content analysis approach. Selected using purposeful sampling, 19 pre-hospital emergency care personnel were interviewed on a semi-structured, personal, in-depth basis. The qualitative data obtained were analyzed using the Graneheim and Lundman’s conventional content analysis approach (2004). Results Based on the qualitative data analysis, 3 themes and 8 subthemes were obtained. The three main themes included professional barriers (lack of clinical knowledge of telecardiology, lack of clinical skill in telecardiology, violation of patients’ privacy, lack of clinical guidelines on telecardiology), medical equipment and telecommunication barriers (poor reception and ineffective means of communication, low charge on the battery of tele-electrocardiogram machines), and organizational management barriers (serious lack of cardiologists available for medical counseling and lack of continual personal development of the telecardiology personnel). Conclusion Senior managers in pre-hospital emergency care services are recommended to use the results of this study to identify the influential factors in using telecardiology and take the necessary measures to eliminate the existing barriers toward making optimal use of telemedicine, thereby improving the quality of care provided for cardiac patients

Отдаленные результаты лечения больных, остеосинтез которым проводился металлическими и биодеградирующими фиксаторами

Clinical and radiological examinations of patients after internal fixation of methaepyphyseal fracture have proved that both polymeric materials (polyglycolide and polyamide-12) possess high extent of biological compatibility. Polymeric fixation devices have not produced any negative effect on normal physiological regeneration of the bone tissue at the fractured segment within 10 to 44 years of follow-up. Therefore these materials can be safely used for manufacturing bone fixation devices for internal fixation fractures of methaepiphyseal areas.Проведені дослідження, з застосуванням клінічних та рентгенологічних обстежень доводять, що патологічних змін кісткової тканини в ділянках синтезованих консолідованих метаепіфізарних переломів в оперативному лікуванні яких застосовувалися фіксатори, виготовлені з полімерних матеріалів полігліколіду та поліаміду П-12, не виявлено на протязі всього терміну спостережень від 10 до 44 років після оперативного втручання. Обидва полімерні матеріали виявлять високу біосумісність, що дозволяє безпечно застосовувати фіксатори виготовлені з даних матеріалів для остеосинтезу метаепіфізарних переломів.Проведенные исследования с использованием клинических и рентгенологических методов исследования подтверждают, что патологических изменений в костной ткани в местах синтезированных консолидированных метаэпифизарных переломов, в оперативном лечении которых использовались фиксаторы, изготовленные из полимерных материалов полигликолида и полиамида-12, не выявлено на протяжении всего срока наблюдения – от 10 до 44 лет после оперативного вмешательства. Оба полимерных материала демонстрируют высокую биологическую совместимость, что позволяет безопасно использовать фиксаторы, изготовленные из данных материалов для остеосинтеза метаэпифизарных переломов

Predictors of major adverse cardiac events following elective stenting of large coronary arteries

Objective: Diameter of the affected coronary artery is an important predictor of restenosis and need for revascularization. In the present study, we investigated the frequency and potential risk factors for major adverse cardiac events following elective percutaneous coronary intervention (PCI) and stenting of large coronary arteries. Methods: We reviewed the data of elective candidates of PCI on a large coronary artery who presented to our center. Demographic, clinical, angiographic and follow-up data of the eligible patients were retrieved from our databank. The study characteristics were then compared between the patients with and without MACE in order to find out the probable risk factors for MACE in patients with large stent diameter. Results: Data of 3043 patients who underwent single vessel elective PCI with a stent diameter of ≥3.5 mm was reviewed. During a median follow up period of 14 months, 64 (2.1%) patients had MACE. TVR was the most common type of MACE that was observed in 29 patients, while 5 patients had cardiac death. Higher serum levels of creatinine, history of cerebrovascular accident (CVA), and use of a drug eluting stent (DES) were significantly associated with MACE. In the multivariate model, history of CVA (odds ratio = 5.23, P = 0.030) and use of DES (odds ratio = 0.048, P = 0.011) were the independent predictors of MACE in patients underwent large coronary artery stenting. Conclusion: This study showed that prior CVA and the use of BMS were the potential risk factors for MACE in patients who were stented on their large coronary arteries

Availability and affordability of blood pressure-lowering medicines and the effect on blood pressure control in high-income, middle-income, and low-income countries: an analysis of the PURE study data

Background: Hypertension is considered the most important risk factor for cardiovascular diseases, but its control is poor worldwide. We aimed to assess the availability and affordability of blood pressure-lowering medicines, and the association with use of these medicines and blood pressure control in countries at varying levels of economic development. Methods: We analysed the availability, costs, and affordability of blood pressure-lowering medicines with data recorded from 626 communities in 20 countries participating in the Prospective Urban Rural Epidemiological (PURE) study. Medicines were considered available if they were present in the local pharmacy when surveyed, and affordable if their combined cost was less than 20% of the households' capacity to pay. We related information about availability and affordability to use of these medicines and blood pressure control with multilevel mixed-effects logistic regression models, and compared results for high-income, upper-middle-income, lower-middle-income, and low-income countries. Data for India are presented separately because it has a large generic pharmaceutical industry and a higher availability of medicines than other countries at the same economic level. Findings: The availability of two or more classes of blood pressure-lowering drugs was lower in low-income and middle-income countries (except for India) than in high-income countries. The proportion of communities with four drug classes available was 94% in high-income countries (108 of 115 communities), 76% in India (68 of 90), 71% in upper-middle-income countries (90 of 126), 47% in lower-middle-income countries (107 of 227), and 13% in low-income countries (nine of 68). The proportion of households unable to afford two blood pressure-lowering medicines was 31% in low-income countries (1069 of 3479 households), 9% in middle-income countries (5602 of 65 471), and less than 1% in high-income countries (44 of 10 880). Participants with known hypertension in communities that had all four drug classes available were more likely to use at least one blood pressure-lowering medicine (adjusted odds ratio [OR] 2·23, 95% CI 1·59–3·12); p<0·0001), combination therapy (1·53, 1·13–2·07; p=0·054), and have their blood pressure controlled (2·06, 1·69–2·50; p<0·0001) than were those in communities where blood pressure-lowering medicines were not available. Participants with known hypertension from households able to afford four blood pressure-lowering drug classes were more likely to use at least one blood pressure-lowering medicine (adjusted OR 1·42, 95% CI 1·25–1·62; p<0·0001), combination therapy (1·26, 1·08–1·47; p=0·0038), and have their blood pressure controlled (1·13, 1·00–1·28; p=0·0562) than were those unable to afford the medicines. Interpretation: A large proportion of communities in low-income and middle-income countries do not have access to more than one blood pressure-lowering medicine and, when available, they are often not affordable. These factors are associated with poor blood pressure control. Ensuring access to affordable blood pressure-lowering medicines is essential for control of hypertension in low-income and middle-income countries. Funding: Population Health Research Institute, the Canadian Institutes of Health Research, Heart and Stroke Foundation of Ontario, Canadian Institutes of Health Research Strategy for Patient Oriented Research through the Ontario SPOR Support Unit, the Ontario Ministry of Health and Long-Term Care, pharmaceutical companies (with major contributions from AstraZeneca [Canada], Sanofi Aventis [France and Canada], Boehringer Ingelheim [Germany amd Canada], Servier, and GlaxoSmithKline), Novartis and King Pharma, and national or local organisations in participating countries