Isolamento e avaliação do potencial citotóxico de derivados fenólicos de Schinus terebinthifolius Raddi (Anacardiaceae)

The EtOH extract from leaves of S. terebinthifolius was subjected to partition between EtOH:H2O and hexane, CH2Cl2, and EtOAc. The phases obtained were evaluated in vitro against human tumoral cell lines and the EtOAc phase exhibited activity. Chromatographic procedures afforded gallic acid (1), methyl (2) and ethyl (3) gallates, trans-catechin (4), quercitrin (5), and afzelin (6), being the first occurrence of 1, 4 and 6 in S. terebinthifolius.In vitro cytotoxic evaluation of 1 - 6 indicated that gallic acid (1) displayed higher activity than ethyl gallate (3) against HL-60 and HeLa cells, while compounds 2, 4 - 6 were inactive

Estimation of thermal properties using only one surface by means of infrared thermography

In this work was used infrared imagery to estimate thermal properties of solid materials. The Two Superficial Hot Points Technique (TSHP) was proposed and it uses heat flux and temperatures measured from a single surface of the sample to estimate the thermal diffusivity and conductivity of the material. By definition, the two parameters to be estimated are correlated and for this reason the gain ratio function concept was used to nullify this correlation, creating two independent objective functions, one for each parameter to be estimated. The gain ratio concept was extended to a three-dimensional semi-infinite model and the surface temperature was measured with infrared thermography. Associated with infrared thermography, the use of a semi-infinite mathematical model creates versatility and the possibility of estimating the properties by assessing only the region where the heat flux was applied. In other words, the geometric and boundary conditions of the sample do not need to be considered in the thermal properties estimation. The TSHP technique takes less than four minutes for temperature monitoring, it is non-destructive and uses only superficial measurements allowing, perhaps, countless in situ applications. In the present work, the thermal properties of a pipe made of Polyvinyl Chloride (PVC) were successfully estimated. In addition, a silicone rubber and copper sample were also tested. The results obtained are in good agreement with the results reported in the literature

Análise de mobilidade entre Cidades Gêmeas: uma abordagem por Lógica Difusa

Esta pesquisa busca analisar o translado entre três grupos de Cidades Gêmeas e através de técnicas de Simulação Computacional e lógica difusa, traduzir um conjunto de entradas linguísticas em pareceres acerca da mobilidade urbana. Deste modo, o objetivo geral desta pesquisa consiste em identificar um conjunto de recomendações para o trânsito entre as cidades de Itajaí e Navegantes. Como critério de análise foram investigados o comportamento de Cidades Gêmeas, separadas por mar ou rio e com concentrações de fluxo semelhantes. Foram investigados o comportamento de dois pares de cidades Brasileiras Itajaí/Navegantes e Florianópolis/São José, além de um terceiro par de cidades: Cambridge/Boston. Com isso foram extraídos dados de eficiência de trânsito, originalmente apresentados como entradas linguísticas de uma rota rápida e uma rota lenta em horários prédeterminados para cada um dos três pares, além disso, foram considerados os custos para o percurso destas rotas considerando o automóvel Onix (mais vendido no Brasil em 2016). Dentre os resultados obtidos se comprovou que as cidades Itajaí/Navegantes, a rota que utiliza o ferry boat, por mais que seja muito mais rápida que a rota alternativa, é menos recomendável, pois o custo de utilização do ferry boat é muito caro. Verifica-se que o uso de uma travessia entre as cidades livre, como é feito nas outras cidades gêmeas, é necessário.

Non-Invasive and Non-Destructive Approach Based Infrared Thermography to Estimate Thermal Properties in Vivo

Estimation of thermal properties in vivo tissue is important to predict and control biological procedures, since they are dependent of temperature behavior. However, in vivo estimation of human thermal properties in a non-invasive and non-damage manner is a challenging task. In this paper, we propose an approach to estimate thermal properties in vivo. The approach is non-invasive and non-damage since it uses only external measurements. Considering the experimental results, the non-invasive procedure using heat flux and temperature variation is a feasible tool to estimate thermal properties in in vivo

Ant colony optimization for variable selection in discriminant linear analysis

A new algorithm using ant colony optimization (ACO) for selection of variables in linear discriminant analysis (LDA) is presented. The role of ACO is explored in the context of LDA classification in which spectral variable multicollinearity is a known cause of generalization problems. The proposed ACO-LDA presents a metaheuristic that mimics the ant's cooperative behavior, randomly depositing pheromones at vector elements corresponding to the most relevant variables. Such cooperative ant-like behavior, which is absent in the genetic algorithm, increases the probability of discarding noninformative variables, favoring construction of more parsimonious models than genetic algorithm–linear discriminate analysis (GA-LDA). The classification performance of ACO-LDA is assessed in two case studies: (i) classification of edible vegetable oils (with respect to base oil) via ultraviolet–visible (UV-Vis) spectrometry and (ii) simultaneous classification of tea samples with respect to type and geographic origin via near-infrared (NIR) spectrometry. In the first study, ACO-LDA was tested in a data set involving wide absorption bands in the UV region with low-resolution and strong spectral overlapping. In the second study, its capacity to manage a data matrix with high dimensionality was evaluated. In both studies, ACO-LDA selected a small subset of variables, which led to correct classifications for almost all of the samples, achieving a performance level similar to the well-established partial least squares–discriminant analysis (PLS-DA), and considerably better than GA-LDA. The use of ACO to select LDA classification variables can minimize generalization problems commonly associated with multicollinearity.Fil: Pontes, Aline S.. Universidade Estadual Da Paraiba.; BrasilFil: Araújo, Alisson. Universidade Estadual Da Paraiba.; BrasilFil: Marinho, Weverton. Universidade Estadual Da Paraiba.; BrasilFil: Goncalves Dias Diniz, Paulo Henrique. Universidade Estadual Da Paraiba.; BrasilFil: Araújo Gomes, Adriano. Universidade Federal do Rio Grande do Sul; BrasilFil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; ArgentinaFil: Silva, Edvan C.. Universidade Estadual Da Paraiba.; BrasilFil: Araújo, Mario C.U.. Universidade Estadual Da Paraiba.; Brasi

Non-preference for oviposition and antibiosis in bean cultivars to Bemisia tabaci biotype B (Hemiptera: Aleyrodidae)

Among the pests that cause reduction on common bean yield, the whitefly Bemisia tabaci biotype B (Hemiptera: Aleyrodidae) stands out. The insect causes direct damages due to its feeding on plants and indirect damages by the sugary excretion of honeydew, providing the development of the sooty mould. In addition this species is an important vector of virus such as the golden bean mosaic virus. Thus, this work aimed to study the non-preference for oviposition and antibiosis in bean cultivars to the whitefly. Experiments were carried out in a greenhouse at Jaboticabal, SP, Brazil, from January to March 2012. The following cultivars were used in the assays: IAC-Centauro, IAC-Una, IAC-Formoso, IAPAR-81, IPR-Eldorado, IPR-Siriri (all resistant); and Perola and IAC-Harmonia (both susceptible), previously screened from field experiments. Cultivars IAC-Harmonia, IPR-Eldorado, IAPAR- 81 and IPR- Siriri were the least preferred for oviposition; and the cultivar IAC-Harmonia extended the whitefly life cycle, expressing nonpreference for feeding and or/antibiosis-type resistance.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq