Epidermolysis Bullosa Nevi: Report of a Case and Review of the Literature

A 10-year-old female patient, being treated for dystrophic bullous epidermolysis in a Pediatric Hospital, was referred to our Dermoscopy Ambulatory because of a newly observed mole in the submandibular area. Clinically, the lesion presented as an irregular double-colored macule of about 2 cm in diameter, with irregular borders, suspicious of malignancy. Dermoscopy showed a multicomponent pattern, with multiple colors, ill-defined network, black blotches, streaks, multiple dots, a blue-whitish veil and granularity at the periphery. Although it had a clinical appearance of malignancy, dermoscopy every semester was proposed due to the revision of a recently described entity, named bullous epidermolysis nevi, that we made in these children. The fragile skin of this particular patient was also taken into account, and overtreatment was avoided. Bullous epidermolysis nevi is the term given to large, asymmetrical and often irregularly pigmented melanocytic nevi that occur in former areas of blistering in patients with the dystrophic forms of the disease. Despite its atypical clinical appearance, and sometimes also atypical dermoscopy, malignant transformation has not been reported yet. Similarly to recurrent nevi, where melanocytes proliferate in a previous area of trauma, clinical aspect, dermoscopy, and histopathology may tempt clinicians to diagnose benign moles as melanoma. Here we report one case of this entity, scarcely reported on in literature, and review clinical and dermatoscopical features of epidermolysis bullosa nevi confronting it with recurrent nevi. The usefulness of dermoscopy as a treatment strategy is stressed

Impact of the COVID-19 pandemic on the epidemiological and clinicopathological profile of cases of primary cutaneous melanoma diagnosed at Professor Rubem David Azulay Institute of Dermatology

SUMMARY: Melanoma is the main cause of death in dermatology (it is an aggressive type of skin cancer being one of the main causes of cancer death) due to its high metastatic power. When detected in early stages, its surgical treatment can be curative. When detected in more advanced stages, its prognosis is reserved and can be lethal. During the period of the COVID-19 pandemic, many medical activities were suspended. There are few data in the literature evaluating the impact of the pandemic on the evolution of patients with melanoma. OBJECTIVES: This study aimed to evaluate the impact of the COVID-19 pandemic on the epidemiological, clinical and histopathological aspects of melanomas diagnosed at the Instituto de Dermatologia Professor Rubem David Azulay (IDPRDA). METHODS: This is an observational, retrospective and unicentric study, where the requests and histopathological reports of skin biopsies performed at IDPRDA between January 2018 and December 2021 were reviewed and their epidemiological and clinicopathological aspects were subsequently evaluated. RESULTS: A significantly lower incidence of melanoma diagnosis was not found during the pandemic years, but patients were diagnosed at more advanced stages of the disease, which shows a delay in diagnosis due to Covid-19

When a clinical-dermoscopic correlation is warranted

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Regressive scalp lesions: Dermoscopic and confocal clues

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