Magnesium Level in Pulmonary Tuberculosis Patients

Abstract: Magnesium plays important roles in physiological function of the body organs because magnesium is an essential mineral. Present study was to determine magnesium levels in serum of fifty pulmonary tuberculosis patients and fifty controls magnesium was determined using a Hitachi atomic absorption spectrophotometer (Tokyo, Japan). Magnesium level was significantly decreased in pulmonary tuberculosis patients as compared with the controls. In order to better understand the role of magnesium in pulmonary tuberculosis further clinical studies are required

Proton Pump Inhibitors: Pantoprazole is the safe drug as compared to Omeprazole drug during treatment of Dyslipidemia.

Introduction: Proton pump inhibitors (PPIs) are commonly used to manage ret-rosternal burning to peptic ulcer disease. Dyslipidemia is also very common in Asian population.Objective: To evaluate the effects of different groups of PPIs like omeprazole, Pan-toprazole, esomeprazole on lipid profile.Methodology: This animal study conducted at the Department of Pharmacology with collaboration of Diagnostic & Research laboratory of Liaquat University of Medical & Health Sciences Jamshoro from 16 Nov to 30 Nov 2020. 24 male rabbit were divided in 3 equal groups. The sample for lipid profile were taken twice; first sample was collected before start of PPPIs, while another sample was taken after six weeks of the treatment with different groups of PPPIs. The lipid profile was ana-lyzed by Cobass Auto analyzer (C-311) of Hitachi at Diagnostic & Research Labora-tory LUMHS. The Statistical analysis was performed by student ‘t’ test and chi square test by using SPSS version 21.Result: The results found were statistically significant (p=<0.05) for omeprazole and esomeprazole while it was insignificant (p=0.247) for pantoprazole. TG’s was signifi-cantly more in group A and B animals as compare to group C animals. Low density Lipoprotein found raised among all groups but the rise was statistically insignifi-cant.Conclusion: Omeprazole exerts significant effects over all observed parameters of lipid profile, esomeprazole showed effects over few parameters, while pantopra-zole showed insignificant effects over lipid profile.Key words: Proton Pump Inhibitors, Low density Lipoprotein, Cholesterol

Association of Serum Zinc level with Pre Eclampsia

BACKGROUND: Pre eclampsia is the commonest obstetrical complication in pregnant women. The etiology of pre eclampsia has yet not been clearly understood. It has a worldwide prevalence of 2–10% of pregnancies and one of the major causes of increase in maternal and perinatal morbidity and mortality. Zinc plays an important role in the course and eventual outcome of human pregnancy and is essential for normal embryogenesis and fetal growth. Zinc deficiency in pregnancy is thought to be associated with pre-eclampsia. OBJECTIVE: The aim of this study was to investigate the serum zinc level in pre-eclampsia. PATIENTS AND METHODS: This Hospital based study conducted at Gynecology Department of Indus Medical Collage, Tando Muhammad Khan, Sindh from October 2015 to March 2016 with the Permission of Head of the Department and Principal of Institute. The study groups consist of 40 consecutive diagnosed cases of pre eclampsia and 40 women with normal pregnancies. The serum zinc level of the subjects under this study was determined using Atomic Absorption Spectrophotometer. RESULTS: The results of our study showed that serum Zinc level among the pre-eclamptic and was statistically significantly low as compared to normotensive pregnant women. CONCLUSION: The findings of current work are statistically significant to establish that concentration of serum zinc among preeclamptic subjects is lower than in the normotensive women during pregnancy

Exploring Types of Waste Generated: A Study of Construction Industry of Pakistan

The construction sector is responsible for providing fundamental physical structure required for living and survival of human life. Increased development works have led in resulting the massive amount of waste generation in developing countries. Due to poor management system on sites, it has become more crucial and exerts several negative impacts on society and the environment. This Unused waste material has a negative impact on the ecosystem and needs a considerable amount of money for recycling, reusing and disposal of the waste. Like other developing countries Pakistan is spending a significant portion of its GDP on handling construction waste. Among the several other factors, the key contributes are highlighted in this study. This study is exploratory work investigating the types of construction waste generated on site and their relative impact of the project cost in construction projects of Pakistan. Through questionnaire the opinion of clients, consultant and constructor have been taken to identify the major types of waste having more impacts on cost and time. Through Average index, severity index and importance index, the probability of occurrence of waste through different materials, severity level of waste production by these materials, and the overall effect of all waste generating materials have been found respectively. Among the materials sand, concrete, tile is the most common materials, which are responsible for a waste generation while time and cost are the two most common non-physical waste generating factors

Motivational Factors for the Implementation of ISO-9001 in Construction Firms of Pakistan

Motivating public and private construction firms to implement various management systems in their firms is not a simple job. Especially in Pakistan, management system is a new practice, most of the construction firms are not aware about the benefits of management system and what will be achieved after the implementation of management system. The implementation of ISO 9001 Quality Management System (QMS) in the construction industry is a continuing development method, particularly in small construction firms. On the other hand, the awareness level and readiness level of construction industry firms in Pakistan is yet very low as associated to other countries of Asia and Europe where ISO 9001 initiated. The purpose current study is to determine most responsible factors which will motivate the public and private construction firms of Pakistan to adopt the QMS (ISO 9001). A questionnaire survey was conducted and a total of 337 out of 553 questionnaires were received from public and private construction firms of AZBAGIKHPUSI areas. The analysis results depict 3 significant factors, which will motivate construction firms of Pakistan to implement ISO 9001 are (1) to qualify for bidding (2) to improve quality management system of company (3) to reduce wastage. Hence, based on these results and findings, the construction companies require ISO 9001 certification system and registration with Pakistan Engineering Council (PEC) as a constitution passed for the construction firms then to qualify for the bidding

Condition Survey for Evaluation of Pavement Condition Index of a Highway

Pavements are major means of highway infrastructure. Maintenance and rehabilitation of these pavements for the required serviceability is a routine problem faced by highway engineers and organizations. Improvement in road management system results in reduction of time and cost, the pavement condition survey plays a big role in the pavement management. The initial phase in setting up a pavement management system (PMS) is road network identification. A vital element of a PMS is the capacity to assess the present condition of a pavement network and anticipation of future condition. The pavement condition index (PCI) is a numerical index generally utilized for the assessment of the operational condition & structural reliability of pavements. Estimation of the PCI is dependent on the results of a visual inspection in which the type, severity, and quantity of distresses are distinguished. In this research, a pavement distress condition rating strategy was utilized to accomplish the goals of this study. The main targets of this research were to categorize the common types of distress that exist on “Lakhi Larkana National Highway (N-105)”, and to estimate the pavement condition index. Using these data, Average PCI for the highway section was calculated. PCI to assess the pavement performance, 10 out of 19 defects were recognized in the pavement, as stated by the PCI method. Results indicated that the common pavement distress types were depressions, polished aggregate, rutting, potholes, block cracking, and alligator cracking

Evaluation of combined utilization of marble dust powder and fly ash on the properties and sustainability of high‑strength concrete

With the recent increase in demand for high-strength concrete, higher cement content is utilized, which has increased the need for cement. The cement industry is one of the most energy-consuming sectors globally, contributing to 10% of global carbon dioxide (CO2) gas emissions and global warming. Similarly, with rapid urbanization and industrialization, a vast number of by-products and waste materials are being generated in abundance, which causes environmental and health issues. Focusing on these two issues, this study aimed to develop an M50-grade eco-friendly high-strength concrete incorporating waste materials like marble dust powder (MDP) and fy ash (FA) as partial cement replacement. 2.5%, 5%, 7.5%, and 10% MDP and FA by weight of total binder was utilized combinedly, such that the 5%, 10%, 15%, and 20% cement content was replaced, respectively. The fresh state properties in terms of workability and hardened state properties in terms of compres�sive and fexural strengths were evaluated at 7, 14, 28, 56, and 90 days. Furthermore, to assess the environmental impact of MDP and FA, the embodied carbon and eco-strength efciency were calculated. Based upon the results, it was observed that a combined 10% (5% MDP and 5% FA) achieved the highest strength; however, 15% (7.5% MDP and 7.5% FA) substitution could be optimal. Furthermore, the combined utilization of FA and MDP also enabled a reduction in the total embodied carbon. It decreased the cost of concrete, resulting in an eco-friendly, high-strength concrete

Population Density of Grey Francolin (Franclinus Pondicrianus L.) in District Tando Allahyar, Sindh, Pakistan

The population density of Grey Francolin (Franclinus Pondicrianus L.) is distributed throughout the Baluchistan, KKPK, Punjab, and Indus plains of Sindh Province, Pakistan. The grey francolin is a prime game bird of our country. This species has been declared threatened worldwide according to the Red Data Book, also published by the International Union for Conservation of Nature in 2018. There is no information available regarding the density of the population of Grey francolin in different populations in the district of Tando Allahyar, Sindh, Pakistan. Keeping this in mind, the present study was carried out to find the density population of Grey francolin birds in the habitat area to observe the conservation measurements. The study was conducted through direct sighting with the help of local residents of the particular areas using the Visual Encounter Method. The observations were recorded at three fixed transects, with a length of 300 to 350 m and a width of 30 to 60 m laid down at every site for recording the birds by nearest line. In Tando Allahyar, Sindh, Pakistan, the population density of Grey francolin varies significantly based on breeding practices and habitat characteristics. The observed densities were 0.90 birds per hectare in cultivated open land and 0.16 birds per hectare in wetland and associated natural vegetation. This suggests a notable influence of habitat and breeding practices on Grey francolin population

SPECTRUM OF PLEURAL EFFUSION DUE TO RENAL PATHOLOGIES AT TERTIARY CARE HOSPITAL

Objective: To determine the spectrum of pleural effusion due to renal pathologies at tertiary care hospital. Patients And Methods: The one year cross sectional study was conducted at tertiary care hospital. All the patients either gender who were diagnosed as chronic kidney disease (on haemodialysis) were included in the study. These patients were allowed to undergo necessary investigations and treatment. All the specific patients had thorough clinical history, relevant clinical examination and important investigations to explore the pulmonary pathology (pleural effusion) while the frequency / percentages (%) and means ±SD computed for study variables. Results: During one year study period total fifty patients with pleural effusion were explored and studied. The frequency for male and female population was 32 (64%) and 18 (36%) with mean ± sd for age of male and female individuals was 59.82±7.83 and 53.85±6.94 respectively. Gender male 30 (60%), female 20 (40%), pleural effusion 32 (64%). The cause includes idiopathic (unknown) 05 (10%), over hydration 15 (30%), heart failure 06 (12%), parapneumonic effusion 08 (16%), uremic pleuritis 05 (10%), tuberculous pleurisy 06 (12%), malignancy (prostate cancer) 05 (10%). Conclusion: Pleural effusion is regular in hospitalized patients getting long haul hemodialysis due to chronic kidney disorders. Keywords: Pleural effusion, Kidney, Lung and Renal disease