14 research outputs found
Towards Wind Energy-based Charging Stations: A Review of Optimization Methods
Due to the growing importance of renewable sources in sustainable energy systems, the strategic deployment of robust optimization techniques plays a crucial role in the design of Electric Vehicle Charging Stations (EVCSs). These stations need to smoothly incorporate renewable sources, ensuring optimal energy utilization. This study provides a comprehensive overview of the methodologies and approaches employed in the enhancement of wind energy based EVCSs. The aim is to discern the most efficacious techniques for optimizing charging stations. Researchers engage diverse strategies and methodologies in the realm of sizing and optimization, encompassing a spectrum of algorithmic implementations and software solutions. Evidently, each algorithm or software application bears distinctive merits and demerits. Singular reliance on a solitary algorithm or software for charging utility optimization is discerned to be potentially limiting. The investigation reveals that achieving better results in Electric Vehicle Charging Station (EVCS) optimization is facilitated by the collaborative use of multiple algorithms like GA, PSO, and ACO, among others, or software tools like Homer or RETScreen
Antibiotic use during pregnancy increases offspring asthma severity in a dose‐dependent manner
Background: The use of antibiotics during pregnancy is associated with increased allergic asthma risk in the offspring, and given that approximately 25% of pregnant women are prescribed antibiotics, it is important to understand the mechanisms contributing to this phenomenon. Currently, there are no studies that directly test this association experimentally. Our objective was to develop a mouse model in which antibiotic treatment during pregnancy results in increased offspring asthma susceptibility.
Methods: Pregnant mice were treated daily from gestation day 8-17 with an oral solution of the antibiotic vancomycin, and three concentrations were tested. At weaning, offspring were subjected to an adjuvant-free experimental asthma protocol using ovalbumin as an allergen. The composition of the gut microbiome was determined in mothers and offspring with samples collected from five different time points; shortchain fatty acids were also analyzed in allergic offspring.
Results: We found that maternal antibiotic treatment during pregnancy was associated with increased offspring asthma severity in a dose-dependent manner. Furthermore, maternal vancomycin treatment during pregnancy caused marked changes in the gut microbiome composition in both mothers and pups at several different time points. The increased asthma severity and intestinal microbiome changes in pups were also associated with significantly decreased cecal short-chain fatty acid concentrations.
Conclusion: Consistent with the "Developmental Origins Hypothesis," our results confirm that exposure to antibiotics during pregnancy shapes the neonatal intestinal environment and increases offspring allergic lung inflammation
Techno-economic analysis of a wind-energy-based charging station for electric vehicles in high-rise buildings in Malaysia
Renewable energy sources have become necessary for long-term energy sustainability due to the increased demand for electric cars and worrisome rises in carbon dioxide emissions from traditional energy sources. Furthermore, transportation is one of the sectors that uses the most energy on the planet, accounting for 24% of overall consumption. Fossil fuels are still the dominant energy source for balancing global demand/supply dynamics. Supporting laws and regulations have enhanced the first phase of environmentally friendly energy-resource consumption. This has spurred the development of new solutions that cut greenhouse-gas emissions and reduce the air pollution produced by internal combustion engines that are fuelled by fossil fuels. Wind energy is one of the clean energy sources that may be utilised for this purpose. Wind energy has been used to power electric-car-charging infrastructure, generally in a hybrid mode with another renewable source. This research examines the possibility of using wind energy as a standalone energy source to support electric-vehicle-charging infrastructure. Using data from Malacca, Malaysia, and HOMER software, the project will build and optimise a standalone wind-powered charging station. An RC-5K-A wind turbine coupled to a battery and converter is the appropriate choice for the system. The findings demonstrate that the turbine can produce 214,272 kWh per year at the cost of USD 0.081/kWh, confirming wind’s future feasibility as an energy-infrastructure support source
Power-Sharing in Bahrain: A Still-Absent Debate
Bahrain was among the first Arab Spring countries in which mass protests arose in February 2011. The authoritarian monarchy, which excludes vast segments of society from fair political and economic participation, opted for the use of force to suppress the mainly peaceful demonstrations, but it could not expunge the protests by a popular movement that continues to exist to this day. The power struggle is occurring along a Sunna-Shia divide that interconnects with regional sectarian tensions. This article investigates powersharing arrangements as an option to deal with such deep divisions. It outlines the historical background of the sectarian tensions in Bahrain and the rudimentary forms of powersharing that have existed there in the past. It then analyses the current debate between the regime and the opposition regarding the distribution of political power. While the reality still seems to be far removed from a power-sharing solution, we nevertheless recommend power-sharing as a feasible way out of the current stalemate
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Impact of the International Nosocomial Infection Control Consortium (INICC)’s multidimensional approach on rates of ventilator-associated pneumonia in intensive care units in 22 hospitals of 14 cities of the Kingdom of Saudi Arabia
To analyze the impact of the International Nosocomial Infection Control Consortium (INICC) Multidimensional Approach (IMA) and use of INICC Surveillance Online System (ISOS) on ventilator-associated pneumonia (VAP) rates in Saudi Arabia from September 2013 to February 2017.
A multicenter, prospective, before–after surveillance study on 14,961 patients in 37 intensive care units (ICUs) of 22 hospitals. During baseline, we performed outcome surveillance of VAP applying the definitions of the CDC/NHSN. During intervention, we implemented the IMA and the ISOS, which included: (1) a bundle of infection prevention practice interventions, (2) education, (3) outcome surveillance, (4) process surveillance, (5) feedback on VAP rates and consequences and (6) performance feedback of process surveillance. Bivariate and multivariate regression analyses were performed using generalized linear mixed models to estimate the effect of intervention.
The baseline rate of 7.84 VAPs per 1000 mechanical-ventilator (MV)-days―with 20,927 MV-days and 164 VAPs―, was reduced to 4.74 VAPs per 1000 MV-days―with 118,929 MV-days and 771 VAPs―, accounting for a 39% rate reduction (IDR 0.61; 95% CI 0.5–0.7; P 0.001).
Implementing the IMA was associated with significant reductions in VAP rates in ICUs of Saudi Arabia
Near-Infrared-Induced Heating of Confined Water in Polymeric Particles for Efficient Payload Release
Stroke in critically ill patients with respiratory failure due to COVID-19: Disparities between low-middle and high-income countries
Purpose: We aimed to compare the incidence of stroke in low-and middle-income countries (LMICs) versus high-income countries (HICs) in critically ill patients with COVID-19 and its impact on in-hospital mortality. Methods: International observational study conducted in 43 countries. Stroke and mortality incidence rates and rate ratios (IRR) were calculated per admitted days using Poisson regression. Inverse probability weighting (IPW) was used to address the HICs vs. LMICs imbalance for confounders. Results: 23,738 patients [20,511(86.4 %) HICs vs. 3,227(13.6 %) LMICs] were included. The incidence stroke/1000 admitted-days was 35.7 (95 %CI = 28.4–44.9) LMICs and 17.6 (95 %CI = 15.8–19.7) HICs; ischemic 9.47 (95 %CI = 6.57–13.7) LMICs, 1.97 (95 %CI = 1.53, 2.55) HICs; hemorrhagic, 7.18 (95 %CI = 4.73–10.9) LMICs, and 2.52 (95 %CI = 2.00–3.16) HICs; unspecified stroke type 11.6 (95 %CI = 7.75–17.3) LMICs, 8.99 (95 %CI = 7.70–10.5) HICs. In regression with IPW, LMICs vs. HICs had IRR = 1.78 (95 %CI = 1.31–2.42, p < 0.001). Patients from LMICs were more likely to die than those from HICs [43.6% vs 29.2 %; Relative Risk (RR) = 2.59 (95 %CI = 2.29–2.93), p < 0.001)]. Patients with stroke were more likely to die than those without stroke [RR = 1.43 (95 %CI = 1.19–1.72), p < 0.001)]. Conclusions: Stroke incidence was low in HICs and LMICs although the stroke risk was higher in LMICs. Both LMIC status and stroke increased the risk of death. Improving early diagnosis of stroke and redistribution of healthcare resources should be a priority. Trial registration: ACTRN12620000421932 registered on 30/03/2020
BJS commission on surgery and perioperative care post-COVID-19
Coronavirus disease 2019 (COVID-19) was declared a pandemic by the WHO on 11 March 2020 and global surgical practice was compromised. This Commission aimed to document and reflect on the changes seen in the surgical environment during the pandemic, by reviewing colleagues' experiences and published evidence