57 research outputs found

    Future Research and Developments on Reuse and Recycling of Steelmaking By-Products

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    In the steel sector, sustainable management of by-products is a key challenge to preserve natural resources and achieve the zero waste goal. In this paper, the main trends of future research and development on reuse and recycling of by-products of the steel industry are presented in the form of a roadmap, which is the outcome of a dissemination project funded by the European Union based on the analysis of the most relevant and recent European projects concerning reuse and recycling of by-products from the steel production cycle. In particular, the developed roadmap highlights the most important topics of future research activities and challenges related to reuse and recycling of by-products from the existing or alternative steelmaking routes. A time horizon of 10 years has been considered, taking into account the European Commission targets to achieve carbon neutrality in a circular economy context. In addition, current technological trends derived from past and ongoing research projects are analysed. Research needs are based on the main categories of by-products and residual materials. Due to the different pathways to reduce CO2 emissions, each category is divided into subcategories considering both current and novel process routes targeting decarbonization of steel production. This work identifies the most urgent and demanding research directions for the coming years based on a survey targeting the steel companies, services providers of the steel industry and research organizations active in the field

    EEG ERP preregistration template

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    This preregistration template guides researchers who wish to preregister their EEG projects, more specifically studies investigating event-related potentials (ERPs) in the sensor space

    Psoriasin (S100A7) expression is altered during skin tumorigenesis

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    BACKGROUND: Psoriasin (S100A7) expression has previously been associated with psoriasiform hyperplasia as well as with tumor progression in breast cancer. Its expression profile for different stages of skin lesions is unknown. The aim of this study was to determine the relationship between psoriasin (S100A7) and tumor progression in skin. METHODS: Psoriasin was assessed by immunohistochemistry and levels of expression determined by semi-quantitative scoring in skin biopsies from 50 patients. The cohort included normal skin, actinic keratosis, squamous carcinoma in-situ, invasive squamous cell carcinoma, and basal cell carcinoma. RESULTS: In normal skin, psoriasin was rarely detected in epidermis but was expressed in underlying adnexae. In abnormal epidermis psoriasin was frequently expressed in abnormal keratinocytes in actinic keratosis, in-situ and invasive squamous cell carcinoma, but was rarely observed in the basal epidermal layer or in superficial or invasive basal cell carcinoma. The highest levels of expression were seen within squamous carcinoma in-situ. Significantly reduced levels of expression were observed in both unmatched (p = 0.0001) and matched (p < 0.004) invasive squamous cell carcinoma. Psoriasin expression within abnormal squamous lesions correlated with mitotic count (r = 0.54, p = 0.0036), however no significant relation was found with the intensity of dermal inflammatory cell infiltrates assessed within each pathology. CONCLUSION: These results suggest that altered psoriasin expression occurs in abnormal epidermis and that downregulation may be related to the onset of invasion in squamous cell carcinoma in skin

    Seismic risk assessment for developing countries : Pakistan as a case study

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    Modern Earthquake Risk Assessment (ERA) methods usually require seismo-tectonic information for Probabilistic Seismic Hazard Assessment (PSHA) that may not be readily available in developing countries. To bypass this drawback, this paper presents a practical event-based PSHA method that uses instrumental seismicity, available historical seismicity, as well as limited information on geology and tectonic setting. Historical seismicity is integrated with instrumental seismicity to determine the long-term hazard. The tectonic setting is included by assigning seismic source zones associated with known major faults. Monte Carlo simulations are used to generate earthquake catalogues with randomized key hazard parameters. A case study region in Pakistan is selected to demonstrate the effectiveness of the method. The results indicate that the proposed method produces seismic hazard maps consistent with previous studies, thus being suitable for generating such maps in regions where limited data are available. The PSHA procedure is developed as an integral part of an ERA framework named EQRAM. The framework is also used to determine seismic risk in terms of annual losses for the study region

    Verhaltenstherapeutische Gruppentherapie bei Depression : die Psychiatrische Kurz-Psychotherapie PKP

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    Ausgehend von Becks zentralem Konstrukt der dysfunktionalen Grundannahmen wurde ein gruppentherapeutisches Konzept der Depressionsbehandlung entwickelt, das das maladaptive Schema der Überlebensregel modifiziert und so wieder den Zugang zu funktionaler Regulation der wichtigen Emotionsbereiche Freude, Angst, Trauer und Wut ermöglicht. Depression wird als Vermeidungsverhalten betrachtet, das diese Emotionen vermeiden soll. Entsprechend wird Depressionstherapie als Emotionsexposition durchgeführt – mit den Leitlinienkonformen Interventionen der kognitiven Verhaltenstherapie. Statt eines vollständigen Überblicks über Therapiekonzepte sollen hier wenige Beispiele herausgegriffen und anschaulich dargestellt werden, so dass ein Transfer in die eigene Praxis möglich wird

    A reconnaissance assessment of probabilistic earthquake accelerations at the Nevada Test Site

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    We have made two interim assessments of the probabilistic ground-motion hazard for the potential nuclear-waste disposal facility at the Nevada Test Site (NTS). The first assessment used historical seismicity and generalized source zones and source faults in the immediate vicinity of the facility. This model produced relatively high probabilistic ground motions, comparable to the higher of two earlier estimates, which was obtained by averaging seismicity in a 400-km-radius circle around the site. The high ground-motion values appear to be caused in part by nuclear-explosion aftershocks remaining in the catalog even after the explosions themselves have been removed. The second assessment used particularized source zones and source faults in a region substantially larger than NTS to provide a broad context of probabilistic ground motion estimates at other locations of the study region. Source faults are mapped or inferred faults having lengths of 5 km or more. Source zones are defined by boundaries separating fault groups on the basis of direction and density. For this assessment, earthquake recurrence has been estimated primarily from historic seismicity prior to nuclear testing. Long-term recurrence for large-magnitude events is constrained by geological estimates of recurrence in a regime in which the large-magnitude earthquakes would occur with predominately normal mechanisms. 4 refs., 10 figs
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