4 research outputs found
V. ANALYSE UND INTERPRETATION VON APG 7,2B-53
- Author
- Alf Mit
- Analyse von Dibelius Großen Einfluß
- Apostelgeschichte
- Auf
- Barrett Brüder
- Bihler
- Brawley Eine
- Brehm
- Christus
- de Identität Kurth
- Die Überlieferung
- Dieser Beginn
- Eine
- Erwägungen von White Dieses Fazit
- Es
- Es
- Es
- Exegeten Auf
- Fortstoßen
- Freilich
- Fähigkeit
- Geltung Tatsächlich
- Hier
- In
- Iukanische Auch
- Jervell
- Jervell So
- Klinghardt Gegen
- Kraus Als Beispiel
- Landesverheißung
- Lindemann Zu Recht
- Lukas
- Légasse Exemplarisch
- Légasse Zu Recht
- Man
- Man
- Man
- Meyer Zu
- Mit
- Neh
- Paesler
- Pilhofer Zu Recht
- Präsenz Bereits Deuterojesaja
- Rückführung des Stammbaums Dem
- Schneider So
- Sie
- Stemberger Das
- Stephanusrede
- Story
- Strecker So
- Vorausverweis
- Wilson Gegen
- ähnen den Tempel Siebzehn SGI
- Äthiopisch
- ömischen Darstellung
- üdischen Literatureer Es
- üngst Eine Interpretation
- Publication venue
- 'Vandenhoeck & Ruprecht GmbH & Co, KG'
- Publication date
- Field of study
III. ABTEILUNG
- Author
- A. Alf
- A. J.
- Adontz N.
- Albertario E.
- Albertella M.
- Altaner B.
- Amantos K.
- Atiya A. S.
- B
- Badcock F. J.
- Badcock F. J.
- Banr P. V. C.
- Bardaisan
- Barden D. B.
- Bartoli M.
- Bauer W.
- Baynes N. H.
- Baynes N. H.
- Baynes N. H.
- Bell H. L
- Beneszewicz W.
- Bespr S.
- Bickermann E.
- Bilabel F.
- Bilabel F.
- Billiger B.
- Bischof
- Bittel K.
- Björck G.
- Boqnignon V.
- Born L. K.
- Bratiann G. J.
- Bronssaleux S.
- Browne L. E.
- Brßhier L.
- C. N.
- Cancig F. V.
- Carolsfeld L. Schnorr
- Casey R. P.
- Casey R. P.
- Ch A.
- Ch A. Delatte
- Chevalier-Vferel M.
- Christ Oriens
- Cini R.
- Collinet P.
- Comfort H.
- Contribution
- Cormick Apocalypse The Elizabeth
- Crawford G. S.
- Creswell K. A. C.
- Dabinovic A.
- Darko E.
- Darko E.
- Das V. COPOVIC
- Dawkins R.M.
- Dawkins R.M.
- de Jerphanion G.
- de Ricci Seymour
- Deanovic M.
- Delehaye H.
- Delehaye H.
- des Adj Zur Bedeutung
- Die
- Dvornik F.
- Dyggye F. Weilbach
- Dölger F.
- E.
- Eck A.
- Ehrhard A.
- Elliger W.
- Erstausgabe Wiener
- Euringer S.
- Excavations
- Fedor Alekseevic Rangtabelle
- Festa N.
- Fogolari
- Fr. S.
- Fr. S.
- Fradinski V.
- Franceschini E.
- Frcek J.
- Frey J.-B.
- G. Kr
- Gabrieli G.
- Garnfl C. A.
- Garufi C. A.
- Gerola G.
- Gerola G.
- Gerola G.
- Ghedini G.
- Gian Cristofano A
- Gibb H.A.R.
- Gnichardan J.
- Gr.
- Gregoire H.
- Gregoire H.
- Guyer S.
- Günther Klans
- H.
- Hanser W.
- Henning W.
- Hermelin Ingeborg
- Hohl E.
- Hohler L.
- Holmes U.T.
- Hopkins Clark
- Janin P.
- Jax K.
- Jonescu G.
- Jonkers E. J.
- Jorga N.
- Jugie M.
- Junglas J. P.
- Kanchtschischwili S.
- Kirsch J. P.
- Klostermann R. Trautmann
- Koethe H.
- Koraes A.
- Krantheimer R.
- Kretschmer P.
- Kriaras M.
- Kriaras M.
- Kroll J.
- L'Orange H. P.
- Lagrange M.-J.
- Lake Kirsopp
- Lasareff V.
- Lascaris A.
- Lebreton J.
- Lefort L. Th.
- Lehnert Anzeige
- Les
- Les
- Levy Ernst
- Ljnngvik H.
- Loyen A.
- L·.
- M
- M.A.A
- Mac Culloch J. A.
- Mader A. E.
- Mader A. E.
- Margolionth D. S.
- Melanges Die V
- Mercati S. G.
- Mercati S.G.
- Mesini G.
- Meyer A.
- Miatev K.
- Mickwitz G.
- Milne J.G.
- Mirambel A.
- Mit Ausstellungen
- Mit S.
- Molitor J.
- Momigliano A.
- Muratori S.
- Möhle A.
- NicoresCü P.
- Nock A. D.
- Nock A.D.
- Novello L.
- Oberziner M.
- Opitz H.-G.
- P
- P.
- P. Kr
- Paladino G. Libertilli
- Paris
- Pavlovä M.
- Peeters P.
- Peeters P.
- Peeters P.
- Peeters P.
- Pensabene G.
- Perry B. E.
- Peterson
- Petkovic V. R.
- Pindartextes
- Pinterovic D.
- Pirenne H.
- Pop D.
- Popovic R. Z.
- Porter W. S.
- Pozzi J.
- Preisendanz K.
- Preisendanz K.
- Pringsheim F.
- Pritchard J. P.
- Quasten J.
- R. A. S. A
- Radojcic N.
- Raptschinsky B.
- Rasenov A.
- Reetz H.
- Rev The Right
- Rice D. Talbot
- Ritz G. Schüttrer
- Roasenda P.
- Robert L.
- Robert L.
- Robert L.
- Roberts E. D.
- Rohlfs G.
- Rom
- Rucker J.
- Runciman S.
- Sanvaget J.
- Saria B.
- Sauer J.
- Schachert A. B.
- Schiller A. A.
- Schiller A.A.
- Schneider C.
- Scholastikos Die K
- Schwartz E.
- Schwarz D.M.
- Schwyzer E.
- Schönbauer E.
- Seliscev A. M.
- Seppelt F. X.
- Sherbom C. D.
- Siadbei J.
- Ski J.
- Sky G.
- Smyth H. W.
- Snijder G. A. S.
- Sola G.
- Sole F.
- Soteriu G. A.
- Soteriu G. A.
- Soteriu Maria
- Soyter G.
- St.
- Staab K.
- Stanojevic St.
- Steinwenter A.
- Stevens C.E.
- Svennung J.
- Swift E. H.
- Taeda
- Taylor L. R.
- Terzaghi N.
- Tourneur V.
- Tritton A. S.
- Une
- Van Sickle C. E.
- Vasilev A. A.
- Vercauteren F.
- Vgl S.
- VIH
- Vlasto P.
- Volbach W. F.
- Vujasinovic SI.
- W. En
- Wace A. J. B.
- Wagenmann J.
- Wagenmann J.
- Weingart M.
- Wiet L. Hautecoeur
- Wilpert J.
- With
- Wnlzinger K.
- Zaloziecky W.
- Zeilgeles G.
- Zeiß H.
- Zernov N.
- Publication venue
- 'Walter de Gruyter GmbH'
- Publication date
- 01/01/1934
- Field of study
Stoma-free survival after anastomotic leak following rectal cancer resection: worldwide cohort of 2470 patients
- Author
- Aalbers Arend G.J.
- Abbas Ayman
- Abbood Ali Hashim
- Abdeen Basel
- Abdelaal Ahmed Samir
- Abdullah Nik A.N.
- Abdulwahed Eman
- Abelevich Alexander
- Abujamra Saleh
- Acar Nihan Coşgun
- Afzal Asma
- Agalianos Christos
- Agapov Mikhail N.
- Agostinelli Laura
- Ahmed Nagm Eldin Abu Elnga
- Ahmed Safia
- Aigner Felix
- Akyol Cihangir
- Al-Eryani Fatima
- Al-Juaifari Maytham A.
- Al-Najami Issam
- Alanez-Saavedra Javier
- Albakry Rudaina
- Alhardan Anas
- Alhisi Ahmed Jehad
- Ali Ahmed K.
- Alkady Eithar
- Allmer Caterina
- Alonso Alfredo
- Alrayes Bourhan M.H.
- Alshareea Entisar
- Altomare Donato F.
- Altrabulsi Amani
- Alvarez-Bautista Francisco E.
- Amano Takahiro
- Amelung Femke J.
- Anderin Kajsa
- Annicchiarico Alfredo
- Ansorena Yolanda Saralegui
- Antona Francisco Blanco
- Antonopoulou Maria-Ioanna
- Aprile Alessandra
- Aranda María J. Pizarro
- Aretxabala Izaskun del Hoyo
- Armao Francesca T.
- Arroyo Antonio
- Ashmore Daniel
- Ashoush Fouad M. Bassyouni
- Atak İbrahim
- Atanasov Boyko
- Atici Semra Demirli
- Atienza Paula González
- Avanagh Dara O.
- Avellaneda Nicolas
- Aversano Alessia
- Aybar Ahmet B. CiftciEngin
- Aydin Oguzhan
- Ayoub Kusay
- Azevedo Constanca
- Baatrup Gunnar
- Baban Bayar
- Badiani Sarit
- Bahadoer Renu R.
- Baili Efstratia
- Balalis Dimitrios
- Balci Bengi
- Balik Emre
- Ballabio Michele
- Baloyiannis Ioannis
- Barbero-Valenzuela Alejandro
- Bavikatte Akshay
- Bazaev Andrey
- Belev Nikolay
- Bellato Vittoria
- Beltrán de Heredia Juan P.
- Belvedere Angela
- Benkabbou Amine
- Benčurik Vladimir
- Bernal-Sprekelsen Juan C.
- Berney Christophe
- Bethune Rob M.
- Bhandari Santosh
- Bhat Sameer
- Binder Alf-Dorian
- Biondi Alberto
- Bisagni Pietro
- Bislenghi Gabriele
- Bissett Ian
- Bişgin Tayfun
- Bjorsum-Meyer Thomas
- Blas Juan L.
- Bloemen Johanne G.
- Boerma Evert-Jan G.
- Bonito Alba Correa
- Borda Francisco Javier García
- Borda-Arrizabalaga Nerea
- Bottazzoli Elisa I.
- Boutall Adam
- Bouvy Nicole D.
- Božič Tajda Košir
- Brachini Gioia
- Bradley Nicholas
- Bremers Andreas J.A.
- Buchs Nicolas
- Buchwald Pamela
- Bulut Mehmet Turker
- Burger Jacobus W.A.
- Burghgraef Thijs A.
- Busund Sondre
- Buzzi Gianluca
- Buğra Dursun
- Calabro Marcello
- Calero-Lillo Aránzazu
- Calik Bulent
- Carbone Fabio
- Carreño-Villarreal Guillermo
- Carrie Augusto
- Carvello Michele
- Carvello Michele
- Catena Fausto
- Cengiz Fevzi
- Cerbo Daniele
- Ceretti Andrea P.
- Chandio Ashfaq
- Chaoui Ahmed
- Charalabopoulos Alexandros
- Chaudhri Sanjay
- Chautems Roland
- Chawla Tabish
- Chawla Tabish
- Cholewa Hannia
- Christodoulidis Grigorios
- Chrysos Emmanuel
- Cifuentes-Ródenas José A.
- Cirillo Bruno
- Ciubotaru Cezar
- Ciubotaru Cezar
- Clerici Federico
- Coco Claudio
- Coetzee Emile
- Colak Elif
- Collard Maxime K.
- Colucci Nicola
- Colás-Ruiz Enrique
- Connelly Tara M.
- Consten Esther C.J.
- Consten Esther C.J.
- Corbellini Carlo
- Cotte Eddy
- Creemers Davy M.J.
- Crescentini Giacomo
- D'Agostino Luca
- D'Alimonte Lucrezia
- D'Hoore André
- da Costa Devesa Helena M.
- da Silva Nigel
- Daester Silvio
- Darias Iván Soto
- Darlin Lotten
- Darwich Haitham
- Dattani Mit
- de Andrés Beatriz
- de Gheldere Charles
- de Graaf Eelco J.R.
- de Groot-Van Veen Irene
- de Haan Jael
- de La Cruz Cuadrado Cristina
- de Lacy F. Borja
- de Manzoni Giovanni
- de Nes Lindsey C.F.
- de Paola Gilda
- de Pasqual Carlo A.
- de Simone Belinda D.
- de Vriendt Stefanie
- de Wilt Johannes H.W.
- de Ángelis Nicola
- Deeknah Abdulqudus
- Defoort Barbara
- deGiuli Maurizio
- Dekker Jan-Willem T.
- Delrio Paolo
- Demirkiran Ahmet
- den Boer Frank
- Denost Quentin
- Dewulf Maxime
- di Cosmo Maria A.
- Di Saverio Salomone
- Dimofte Gabriel-Mihail
- Dinaux Anne M.
- Dittrich Luca S.
- Diéguez Beatriz
- Docampo Iria Losada
- Dogan Lutfi
- Doornebosch Pascal G.
- Drozdov Evgeniy S.
- Dudi-Venkata Nagendra N.
- Dursun Ayberk
- Duzgun Ozgul
- Dziakova Jana
- Díez-Alonso Manuel
- Echaniz Garazi Elorza
- Echiguer Sabrillah
- Eduard Galliamov
- Egea Jorge García
- el Muhtaseb Mohammad S.
- El-Massoudi Youssef
- Elhadi Muhammed
- Elshennawy Eslam M.
- Enriquez-Navascués José M.
- Erdinc Kemal
- Eriksen Jacob D.
- Ersryd Amanda L.
- Escartín Jorge
- Espín-Basany Eloy
- Estaire-Gómez Mercedes
- Estefania Diego
- Ewedah Moataz
- Fabbri Nicolo
- Fares Hala
- Farguell Jordi
- Faria Luis Queiroz
- Farnesi Francesca
- Fazzin Marta
- Feo Carlo V.
- Ferenschild Floris T.
- Fernández C.L.
- Fernández-Hevia María
- Fernández-Hurtado Ignacio
- Fernández-Martínez Daniel
- Ferreira Catia
- Ferreira Rita Marques
- Ferrer Rocío
- Filimonov Victor B.
- Filipov Emil
- Fioravanti Emanuela
- Flamey Nicolas
- Florea Sabrina
- Folkesson Joakim
- Foppa Caterina
- Foppa Caterina
- Forgan Tim
- Fowler George E.
- Frasson Matteo
- Frivold Tone
- Frontali Alice
- Fujiwara Hajime
- Futaba Kaori
- Gaard Maria
- Gadan Soran
- Galleano Raffaele
- Gallo Gaetano
- García-Flórez Luis J.
- Gareb Fahed
- Garmanova Tatiana
- Garulli Gianluca
- Gecim Ibrahim E.
- Geitenbeek Ritch
- George Sarah
- Ghazouani Omar
- Ghignone Federico
- Ghmagh Reem
- Gialamas Eleftherios
- Gielis Manuel
- Giuffrida Mario
- Gobut Huseyin
- Golshani Parisa
- Gonzalez Ricardo
- Gonzálvez Paula
- Goutard Claire-Angéline
- Grass Julia-Kristin
- Graure Giorgiana M.
- Gregussen Hilde
- Greijdanus Nynke G.
- Gribnev Petar
- Grosek Jan
- Grossi Ugo
- Grotenhuis Brechtje A.
- Gruter Alexander A.J.
- Guel-Klein Safak
- Guenin Marc-Olivier
- Gunenc Erşan
- Gurjar Shashank
- Gurtler Thomas
- Guzel Melek
- Gómez Tania
- Gómez-Abril Segundo Á.
- Gómez-Jurado María J.
- Haberal Elifcan
- Haddad Anis
- Hajjaj Baraa Nabil
- Hamdan Alaa
- Hamid Hytham K.S.
- Hammoodi Hayder
- Hani Mohammad Bani
- Hannink Gerjon
- Hasan Bassam
- Hassan Naya
- Hassan Soha Y.
- Havenga Klaas
- Hazen Sanne J.A.
- Heemskerk Jeroen
- Heesink Vera
- Heidsma Charlotte M.
- Heijnen Bob H.M.
- Herman Ayesiga
- Hernández Miguel
- Herrero Eduardo Ferrero
- Hess Gabriel F.
- Ho Man-Fung
- Ho Yiu M.
- Hoff Christiaan
- Hol Jeroen C.
- Hollington Paul
- Holman Fabian A.
- Hompes Roel
- Hoogteijling Tijs J.
- Huguet José M. Muguerza
- Hulshof Lorenzo G.W.L.
- Hussein Mohamed
- Iacomino Alessandro
- Ibrahim Aini F.
- Ismail Razif
- Ivanov Tsvetomir
- Iversen Lene H.
- Jadid Kaveh Dehlaghi
- Jakubauskas Matas
- Jakubauskiene Lina
- Jangmalm Staffan
- Janssen Paul T.J.
- Jarimba Aldo M. Rodrigues
- Jou-Valencia Daniela
- Julaihi Rokayah
- Jutesten Henrik
- Kacem Montasser
- Kader Rawaz
- Kamer Erdinc
- Kapadia Raj
- Kara Yasin
- Karamanliev Martin
- Karavokyros Ioannis
- Karmi Fahed
- Karsten Tom
- Karydakis Lysandros
- Kaya Tayfun
- Kelly Michael E.
- Keskin Metin
- Ketelaers Stijn H.J.
- Khader Ahmed A.E.
- Khedr Gehan Abd Elatti
- Koc Mehmet A.
- Koemans Willem J.
- Konishi Tsuyoshi
- Korkolis Dimitrios
- Kostromitskiy Dmitriy N.
- Kozan Ramazan
- Košir Jurij A.
- Kraft Miquel
- Krastev Panche
- Krohn Nina
- Kroon Hidde M.
- Kryzauskas Marius
- Kulle Cemil B.
- Kulle Cemil B.
- Kusters Miranda
- Kynaston James
- La Terra Antonio
- Lacy Antonio M.
- Lambrechts Anton
- Lamme Bas
- Lamparelli Michael
- Lantone Giuliano
- Lapolla Pierfrancesco
- Lara Juan E. Sánchez
- Larcinese Antonella
- Larkin John O.
- Larkin John O.
- Larsson Per-Anders
- Latkauskas Tadas
- Lauka Lelde
- Leeuwenburgh Marjolein M.
- Lefevre Jérémie H.
- Leijtens Jeroen W.A.
- Leung Edmund
- Leventoğlu Sezai
- Lindqvist Ebba
- Liu Jianliang
- Longhi Marco
- Lopez Jose M. Gil
- Lorenzon Laura
- Lorusso Leonardo
- Losada Manuel
- Lucchi Andrea
- Luncă Sorinel
- Lutfi Hamid
- Lydrup Marie-Louise
- López-Lara Manuel
- López-Rodríguez-Arias Francisco
- Macau Florin
- Machackova Maria
- Maghrebi Houcine
- Majbar Mohammed A.
- Mak Tony Wing-Chung
- Manatakis Dimitrios
- Mansour Ali
- Manzo Carlo A.
- Marchegiani Francesco
- Marcos Elena Bermejo
- Mariani Nicolò M.
- Marinelli Andreas
- Markaryan Daniil G.
- Maroli Annalisa
- Marques Sonia M. Ribeiro
- Martinek Lubomir
- Martins Sonia Fortuna
- Martínez María Labalde
- Martínez-Pinedo Carlos
- Maslyankov Svilen
- Massey Lisa
- Matthiessen Peter
- Mattioni Laura A.
- Matías-García Belén
- McCormick Paul H.
- McCullough Peter
- Mehigan Brian J.
- Melling Nathaniel
- Melnikov Andrey A.
- Mendes Ana Filipa Dias
- Mendoza-Moreno Fernando
- Meroni Paola
- Mia Imraan
- Mikalauskas Saulius
- Mingoli Andrea
- Mishra Amitabh
- Mitteregger Martin
- Miu Victor
- Moctezuma-Velázquez Paulina
- Mohamed Abudi
- Mohsine Raouf
- Monib Fatma A.
- Monson John
- Montero José A. Alcázar
- Montroni Isacco
- Morales Bernaldo de Quirós Javier T.
- Morgan Matthew
- Msherghi Ahmed A.
- Mueller Simone
- Mugla Naser
- Mukherjee Tanmoy
- Muratore Andrea
- Muriel Jorge Sancho
- Musters Gijsbert D.
- Muñoz-Collado Salvador
- Muşină Ana-Maria
- Mínguez-Ruiz Germán
- Nair Gavin
- Navarro-Sánchez Antonio
- Neary Peter
- Negoi Ionut
- Negoita Valentina M.
- Nespoli Luca
- Ng Simon Siuman
- Niazi Ammar
- Nichita Vladimir-Ion
- Niemer Quirine
- Nieto-Moreno Elena
- Nilsson Karl
- Nonner Joost
- Novello Simone
- Nygren Jonas
- O'Grady Greg
- Obihara Ndidi J.
- Oldani Massimo
- Oliveira Antonio
- Oosterling Steven J.
- Opocher Enrico
- Osborne Laura
- Ozata İbrahim H.
- Ozgur İlker
- Ozkan Omer Faruk
- Pachajoa Diana A. Pantoja
- Palini Gian M.
- Panel Nathalie
- Panis Yves
- Parc Yann
- Parise Cristiano
- Park Jennifer M.
- Parodi Matias
- Pasini Francesco
- Pasini Franceso
- Passuello Nicola
- Pattyn Paul
- Pavlov Vasil
- Peeters Koen C.M.J.
- Pellino Gianluca
- Pennings Alexander J.
- Pereira Ricardo
- Perez Daniel
- Perez Rodrigo O.
- Perivoliotis Konstantinos
- Perrone Gennaro
- Persiani Roberto
- Pesce Antonio
- Petropolou Thalia
- Pezzuto Roberto
- Picciariello Arcangelo
- Picone Emanuele
- Pikuniene Ingrida
- Pinto Francisca Lima
- Pire-Abaitua Gerardo
- Pirozzolo Giovanni
- Piyadeoğlu Deniz
- Plastiras Aris
- Pletinckx Pieter
- Polat Fatih
- Polle Sebastiaan W.
- Polydorou Adreas
- Porta Andrea
- Poskus Tomas
- Pratschke Johann
- Pringle Heather C.M.
- Puca Lucia
- Pucciarelli Salvatore
- Qandeel Mahmoud W.M.
- Quintana Rita E. Medina
- Quiroga Ignacio Bodega
- Quiroga-Valcárcel Ana
- Rabadi Alexander
- Ramboiu Stefan Patrascu Sandu D.
- Ramsay George
- Rani Pallavi
- Rani Pallavi
- Rauf Hareem
- Rauf Hareem
- Recordare Alfonso
- Reddavid Rossella
- Rega Daniela
- Reudink Muriël
- Riedl Peter
- Riis Rolf
- Ripoli Maria Cristina
- Ris Frederic
- Rizzo Gianluca
- Roată Cristian-Ene
- Rodimov Sergey V.
- Rodríguez Carlos Sáez-Cazallas
- Rodríguez-Infante Antonio
- Romano Angela
- Rompou Aliki
- Roos Daphne
- Roscio Francesco
- Rosman Camiel
- Rotholtz Nicolas
- Rottoli Matteo
- Ruiz Hernan
- Runau Francois
- Rutegård Martin
- Rutten Harm J.T.
- Ruíz-García Pablo
- Ryan Jessica
- Rydbeck Daniel
- Saad Ahmad
- Sacchi Matteo M.
- Sacchi Matteo M.
- Sainz-Hernández Juan C.
- Salgado-Nesme Noel
- Salomon Mario
- Sambucci Daniele
- Sammarco Giuseppe
- Sammour Tarik
- Sampietro Gianluca M.
- Samsa Mehmet Veysi
- Santacruz Carlos Cerdán
- Santillan Mateo
- Santoro Giulio A.
- Sari Ahmet Can
- Sarmah Panchali
- Sarveswaran Janahan
- Sauvain Marc-Olivier
- Scabini Stefano
- Scheurink Lieke
- Schizas Dimitrios
- Schultz Johannes K.
- Sebai Amine
- Sebastian Boby
- Segelman Josefin
- Seitinger Gerald
- Semiao Miguel
- Septiem Javier García
- Serralta Daniel
- Shaban Mohamed
- Shaikh Shafaque
- Shapiro Joël
- Siaw Oliver
- Sibiç Osman
- Sica Giuseppe
- Sietses Colin
- Singh Baljit
- Singh Nirbhaibir
- Singh-Ranger Deepak
- Sinibaldi Giovanni
- Siragusa Leandro
- Sivrikoz Emre
- Sjo Ole H.
- Sjostrom Olle
- Skrovina Matej
- Sköldberg Filip
- Slavchev Mihail
- Slooter Gerrit D.
- Smeeing Diederik P.J.
- Sokmen Selman
- Sokolov Manol
- Soler-Silva Álvaro
- Solomon Michael
- Soriero Domenico
- Souadka Amine
- Spinelli Antonino
- Spinelli Antonino
- Spolverato Gaya
- Staffan Maria
- Stefanescu Victor
- Steller Ernst J.
- Stienstra Roxane M.
- Stoica Bogdan
- Stoica Bogdan
- Suchkov Igor A.
- Sultan Hytham
- Surlin Valeriu M.
- Suárez Marta Castro
- Suárez-Sánchez Aida
- Syllaios Athanasios
- Sánchez Teresa Rubio
- Sánchez-Guillén Luis
- Tababa Osama W.E.
- Taha-Mehlitz Stephanie
- Talboom Kevin
- Talsma Aaldert K.
- Tamelis Algimantas
- Tamini Nicolò
- Tanase Ioan
- Tanis Pieter J.
- Tantoura Mohammad
- Tanzanu Marta
- Tasende-Presedo Marta M.
- Tasis Nikolaos
- Taverne Sophie B.M.
- Tejedor Patricia
- Teras Juri
- Teras Roland M.
- Tiefenthal Marit
- Tomasicchio Giovanni
- Tomažič Aleš
- Tonchev Pencho
- Toorenvliet Boudewijn R.
- Torres María T.
- Toso Christian
- Tsimogiannis Konstantinos
- Tuynmann Jurriaan B.
- Tzovaras George
- Ubels Sander
- Ugolini Giampaolo
- Ulgur Hanife Şeyda
- Uluk Deniz
- Vailas Michail
- Vailati Bruna B.
- van Dalsen Annette D.
- van den Broek Nathalie E.J.
- van den Hengel Berber
- van der Burg Sjirk
- van der Zijden Charlène J.
- van Gerven Pieter
- van Kessel Charlotte S.
- van Praagh Jasper B.
- van Schaik Ted G.
- van Westreenen Hendrik L.
- van Workum Frans
- Vanclooster Patrick
- Vansteenbrugge Louis
- Vasile Mihai
- Venianaki Maria
- Verdaasdonk Emiel G.G.
- Vergara-Fernández Omar
- Vermaas Maarten
- Verstappen Sonja
- Vignotto Chiara
- Villar Óscar García
- Vittori Laura
- Vles Wouter J.
- von Flue Markus
- Voron Thibault
- Vosbeek Noortje
- Vuagniaux Aurelie
- Vázquez Andrea
- Waqar Usama
- Waqar Usama
- Ward Nicholas
- Warden Claire
- Westerterp Marinke
- Wienholts Kiedo
- Wiering Bastiaan
- Wijma Allard G.
- Wildeboer Aurelia C.L.
- Wolthuis Albert
- Wong Michael P.K.
- Woods Kayla
- Xenaki Sofia
- Xynos Evangelos
- Yalkin Omer
- Yanishev Alexey
- Yuksel Osman
- Zabala Jesús Gómez
- Zakaria Andee D.
- Zakaria Zaidi
- Zanini Nicola
- Zanus Giacomo
- Zazo Aya
- Zazo Rama
- Zucchella Martino
- Zukanović Goran
- Zwakman Marije
- Çakir Murat
- Ćosić Jurica
- Šantak Goran
- Šimleša Damir
- Šlenfuktas Vygintas
- Žilinskas Justas
- Publication venue
- Publication date
- 01/12/2023
- Field of study
Background: The optimal treatment of anastomotic leak after rectal cancer resection is unclear. This worldwide cohort study aimed to provide an overview of four treatment strategies applied. Methods: Patients from 216 centres and 45 countries with anastomotic leak after rectal cancer resection between 2014 and 2018 were included. Treatment was categorized as salvage surgery, faecal diversion with passive or active (vacuum) drainage, and no primary/secondary faecal diversion. The primary outcome was 1-year stoma-free survival. In addition, passive and active drainage were compared using propensity score matching (2: 1). Results: Of 2470 evaluable patients, 388 (16.0 per cent) underwent salvage surgery, 1524 (62.0 per cent) passive drainage, 278 (11.0 per cent) active drainage, and 280 (11.0 per cent) had no faecal diversion. One-year stoma-free survival rates were 13.7, 48.3, 48.2, and 65.4 per cent respectively. Propensity score matching resulted in 556 patients with passive and 278 with active drainage. There was no statistically significant difference between these groups in 1-year stoma-free survival (OR 0.95, 95 per cent c.i. 0.66 to 1.33), with a risk difference of -1.1 (95 per cent c.i. -9.0 to 7.0) per cent. After active drainage, more patients required secondary salvage surgery (OR 2.32, 1.49 to 3.59), prolonged hospital admission (an additional 6 (95 per cent c.i. 2 to 10) days), and ICU admission (OR 1.41, 1.02 to 1.94). Mean duration of leak healing did not differ significantly (an additional 12 (-28 to 52) days). Conclusion: Primary salvage surgery or omission of faecal diversion likely correspond to the most severe and least severe leaks respectively. In patients with diverted leaks, stoma-free survival did not differ statistically between passive and active drainage, although the increased risk of secondary salvage surgery and ICU admission suggests residual confounding
Stoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort.
- Author
- Abbas Ayman
- Abbood Ali Hashim
- Abdeen Basel
- Abdelaal Ahmed Samir
- Abdullah Nik A N
- Abdulwahed Eman
- Abelevich Alexander
- Abu Elnga Ahmed Nagm Eldin
- Abujamra Saleh
- Acar Nihan Coşgun
- Afzal Asma
- Agalianos Christos
- Agapov Mikhail N
- Agostinelli Laura
- Ahmed Safia
- Aigner Felix
- Akyol Cihangir
- Al-Eryani Fatima
- Al-Juaifari Maytham A
- Al-Najami Issam
- Alanez-Saavedra Javier
- Albakry Rudaina
- Alcázar Montero José A
- Alhardan Anas
- Alhisi Ahmed Jehad
- Ali Ahmed K
- Alkady Eithar
- Allmer Caterina
- Alonso Alfredo
- Alrayes Bourhan M H
- Alshareea Entisar
- Altomare Donato F
- Altrabulsi Amani
- Alvarez-Bautista Francisco E
- Amano Takahiro
- Amelung Femke J
- Anderin Kajsa
- Annicchiarico Alfredo
- Ansorena Yolanda Saralegui
- Antona Francisco Blanco
- Antonopoulou Maria-Ioanna
- Aprile Alessandra
- Armao Francesca T
- Arroyo Antonio
- Ashmore Daniel
- Atak İbrahim
- Atanasov Boyko
- Atici Semra Demirli
- Atienza Paula González
- Avanagh Dara O
- Avellaneda Nicolas
- Aversano Alessia
- Aydın Oguzhan
- Ayoub Kusay
- Azevedo Constança
- Baatrup Gunnar
- Baban Bayar
- Badiani Sarit
- Baili Efstratia
- Balalis Dimitrios
- Balci Bengi
- Balık Emre
- Ballabio Michele
- Baloyiannis Ioannis
- Barbero-Valenzuela Alejandro
- Bassyouni Ashoush Fouad M
- Bavikatte Akshay
- Bazaev Andrey
- Belev Nikolay
- Bellato Vittoria
- Beltrán de Heredia Juan P
- Belvedere Angela
- Benkabbou Amine
- Benčurik Vladimir
- Bernal-Sprekelsen Juan C
- Berney Christophe
- Bethune Rob M
- Bhandari Santosh
- Bhat Sameer
- Binder Alf-Dorian
- Biondi Alberto
- Bisagni Pietro
- Bislenghi Gabriele
- Bissett Ian
- Bişgin TAYFUN
- Bjørsum-Meyer Thomas
- Blas Juan L
- Bloemen Johanne G
- Boerma Evert-Jan G
- Bonito Alba Correa
- Borda Francisco Javier García
- Borda-Arrizabalaga Nerea
- Bottazzoli Elisa I
- Boutall Adam
- Bouvy Nicole D
- Božič Tajda Košir
- Brachini Gioia
- Bradley Nicholas
- Bremers Andreas J A
- Buchs Nicolas
- Buchwald Pamela
- Bulut Mehmet Türker
- Burger Jacobus W A
- Burghgraef Thijs A
- Busund Sondre
- Buzzi Gianluca
- Buğra Dursun
- Calabrò Marcello
- Calero-Lillo Aránzazu
- Calik Bulent
- Carbone Fabio
- Carreño-Villarreal Guillermo
- Carrie Augusto
- Carvello Michele
- Carvello Michele
- Catena Fausto
- Cengiz Fevzi
- Cerbo Daniele
- Ceretti Andrea P
- Chandio Ashfaq
- Chaoui Ahmed
- Charalabopoulos Alexandros
- Chaudhri Sanjay
- Chautems Roland
- Chawla Tabish
- Chawla Tabish
- Cholewa Hannia
- Christodoulidis Grigorios
- Chrysos Emmanuel
- CiftciEngin Aybar Ahmet B
- Cifuentes-Ródenas José A
- Cirillo Bruno
- Ciubotaru Cezar
- Ciubotaru Cezar
- Clerici Federico
- Coco Claudio
- Coetzee Emile
- Colak Elif
- Collard Maxime K
- Colucci Nicola
- Colás-Ruiz Enrique
- Connelly Tara M
- Consten Esther C J
- Consten Esther C J
- Corbellini Carlo
- Cotte Eddy
- Creemers Davy M J
- Crescentini Giacomo
- D'Agostino Luca
- D'Alimonte Lucrezia
- D'Hoore André
- da Costa Devesa Helena M
- da Silva Nigel
- Daester Silvio
- Darias Iván Soto
- Darlin Lotten
- Darwich Haitham
- Dattani Mit
- de Andrés Beatriz
- de Gheldere Charles
- de Graaf Eelco J R
- de Groot-van Veen Irene
- de Haan Jael
- de La Cruz Cuadrado Cristina
- de Lacy Francisco B
- de Manzoni Giovanni
- de Nes Lindsey C F
- de Paola Gilda
- de Pasqual Carlo A
- de Simone Belinda D
- de Vriendt Stefanie
- de Wilt Johannes H W
- Deeknah Abdulqudus
- Defoort Barbara
- deGiuli Maurizio
- Dekker Jan-Willem T
- Del Hoyo Aretxabala Izaskun
- Delrio Paolo
- Demirkiran Ahmet
- den Boer Frank
- Denost Quentin
- Dewulf Maxime
- deÁngelis Nicola
- di Cosmo Maria A
- Di Saverio Salomone
- Dimofte Gabriel-Mihail
- Dinaux Anne M
- Dittrich Luca S
- Diéguez Beatriz
- Docampo Iria Losada
- Dogan Lütfi
- Doornebosch Pascal G
- Drozdov EvgeniyS
- Dudi-Venkata Nagendra N
- Dursun Ayberk
- Dziakova Jana
- Düzgün Özgül
- Echaniz Garazi Elorza
- Echiguer Sabrillah
- Eduard Galliamov
- Egea Jorge García
- El Muhtaseb Mohammad S
- El-Massoudi Youssef
- Elhadi Muhammed
- Elshennawy Eslam M
- Enriquez-Navascués José M
- Erdinc Kemal
- Eriksen Jacob D
- Ersryd Amanda L
- Escartín Jorge
- Espín-Basany Eloy
- Estaire-Gómez Mercedes
- Estefanía Diego
- Ewedah Moataz
- Fabbri Nicolò
- Fares Hala
- Farguell Jordi
- Faria Luis Queiroz
- Farnesi Francesca
- Fazzin Marta
- Feo Carlo V
- Ferenschild Floris T
- Fernández Cristina López
- Fernández-Hevia María
- Fernández-Hevia María
- Fernández-Hurtado Ignacio
- Fernández-Martínez Daniel
- Fernández-Martínez Daniel
- Ferreira Cátia
- Ferreira Rita Marques
- Ferrer Rocío
- Filimonov Victor B
- Filipov Emil
- Fioravanti Emanuela
- Flamey Nicolas
- Florea Sabrina
- Folkesson Joakim
- Foppa Caterina
- Foppa Caterina
- Forgan Tim
- Fowler George E
- Frasson Matteo
- Frivold Tone
- Frontali Alice
- Fujiwara Hajime
- Futaba Kaori
- Gaard Maria
- Gadan Soran
- Galleano Raffaele
- Gallo Gaetano
- García-Flórez Luis J
- García-Flórez Luis J
- Gareb Fahed
- Garmanova Tatiana
- Garulli Gianluca
- Gecim Ibrahim E
- Geitenbeek Ritch
- George Sarah
- Ghazouani Omar
- Ghignone Federico
- Ghmagh Reem
- Gialamas Eleftherios
- Gielis Manuel
- Gil Lopez Jose M
- Giuffrida Mario
- Golshani Parisa
- Gonzalez Ricardo
- Gonzálvez Paula
- Goutard Claire-Angéline
- Grass Julia-Kristin
- Graure Giorgiana M
- Gregussen Hilde
- Greijdanus Nynke G
- Gribnev Petar
- Grosek Jan
- Grossi Ugo
- Grotenhuis Brechtje A
- Grüter Alexander A J
- Guel-Klein Safak
- Guenin Marc-Olivier
- Gurjar Shashank
- Gómez Tania
- Gómez-Abril Segundo Á
- Gómez-Jurado María J
- Göbüt Hüseyin
- Günenç Erşan
- Gürtler Thomas
- Güzel Melek
- Haberal Elifcan
- Haddad Anis
- Hajjaj Baraa Nabil
- Hamdan Alaa
- Hamid Hytham K S
- Hammoodi Hayder
- Hani Mohammad Bani
- Hannink Gerjon
- Hasan Bassam
- Hassan Naya
- Hassan Soha Y
- Havenga Klaas
- Hazen Sanne J A
- Heemskerk Jeroen
- Heesink Vera
- Heidsma Charlotte M
- Heijnen Bob H M
- Herman Ayesiga
- Hernández Miguel
- Herrero Eduardo Ferrero
- Hess Gabriel F
- Ho Man-Fung
- Ho Yiu M
- Hoff Christiaan
- Hol Jeroen C
- Hollington Paul
- Holman Fabian A
- Hompes Roel
- Hoogteijling Tijs J
- Hulshof Lorenzo G W L
- Hussein Mohamed
- Iacomino Alessandro
- Ibrahim Aini F
- Ismail Razif
- Ivanov Tsvetomir
- Iversen Lene H
- Jadid Kaveh Dehlaghi
- Jakubauskas Matas
- Jakubauskiene Lina
- Jangmalm Staffan
- Janssen Paul T J
- Jou-Valencia Daniela
- Julaihi Rokayah
- Jutesten Henrik
- Kacem Montasser
- Kader Rawaz
- Kamer Erdinc
- Kapadia Raj
- Kara Yasin
- Karamanliev Martin
- Karavokyros Ioannis
- Karmi Fahed
- Karsten Tom
- Karydakis Lysandros
- Kaya Tayfun
- Kelly Michael E
- Keskin Metin
- Ketelaers Stijn H J
- Khader Ahmed A E
- Khedr Gehan Abd Elatti
- Koc Mehmet A
- Koemans Willem J
- Konishi Tsuyoshi
- Korkolis Dimitrios
- Kostromitskiy Dmitriy N
- Kozan Ramazan
- Košir Jurij A
- Kraft Miquel
- Krastev Panche
- Krohn Nina
- Kroon Hidde M
- Kryzauskas Marius
- Kulle Cemil B
- Kulle Cemil B
- Kusters Miranda
- Kynaston James
- Lacy Antonio M
- Lambrechts Anton
- Lamme Bas
- Lamparelli Michael
- Lantone Giuliano
- Lapolla Pierfrancesco
- Larcinese Antonella
- Larkin John O
- Larkin John O
- Larsson Per-Anders
- Latkauskas Tadas
- Lauka Lelde
- Leeuwenburgh Marjolein M
- Lefevre Jérémie H
- Leijtens Jeroen W A
- Leung Edmund
- Leventoğlu Sezai
- Lindqvist Ebba
- Liu Jianliang
- Longhi Marco
- Lorenzon Laura
- Lorusso Leonardo
- Losada Manuel
- Lucchi Andrea
- Luncă Sorinel
- Lutfi Hamid
- Lydrup Marie-Louise
- López-Lara Manuel
- López-Rodríguez-Arias Francisco
- Macau Florin
- Machackova Maria
- Maghrebi Houcine
- Majbar Mohammed A
- Mak Tony Wing-Chung
- Manatakis Dimitrios
- Mansour Ali
- Manzo Carlo A
- Marchegiani Francesco
- Marcos Elena Bermejo
- Mariani Nicolò M
- Marinelli Andreas
- Markaryan Daniil G
- Maroli Annalisa
- Martins Sónia Fortuna
- Martínek Lubomír
- Martínez María Labalde
- Martínez-Pinedo Carlos
- Maslyankov Svilen
- Massey Lisa
- Matthiessen Peter
- Mattioni Laura A
- McCormick Paul H
- McCullough Peter
- Medina Quintana Rita E
- Mehigan Brian J
- Melling Nathaniel
- Melnikov Andrey A
- Mendes Ana Filipa Dias
- Meroni Paola
- Mia Imraan
- Mikalauskas Saulius
- Mingoli Andrea
- Mishra Amitabh
- Mitteregger Martin
- Miu Victor
- Moctezuma-Velázquez Paulina
- Mohamed Abudi
- Mohsine Raouf
- Monib Fatma A
- Monson John
- Montroni Isacco
- Morales Bernaldo de Quirós Javier T
- Morgan Matthew
- Msherghi Ahmed A
- Mueller Simone
- Mugla Naser
- Muguerza Huguet José M
- Mukherjee Tanmoy
- Muratore Andrea
- Muriel Jorge Sancho
- Musters Gijsbert D
- Muñoz-Collado Salvador
- Mușină Ana-Maria
- Mínguez-Ruiz Germán
- Nair Gavin
- Navarro-Sánchez Antonio
- Neary Peter
- Negoi Ionut
- Negoita Valentina M
- Nespoli Luca
- Ng Simon Siu-Man
- Niazi Ammar
- Nichita Vladimir-Ion
- Niemer Quirine
- Nieto-Moreno Elena
- Nilsson Karl
- Nonner Joost
- Novello Simone
- Nygren Jonas
- O'Grady Greg
- Obihara Ndidi J
- Oldani Massimo
- Oliveira António
- Oosterling Steven J
- Opocher Enrico
- Osborne Laura
- Osić Jurica
- Palini Gian M
- Panel Nathalie
- Panis Yves
- Pantoja Pachajoa Diana A
- Parc Yann
- Parise Cristiano
- Park Jennifer M
- Parodi Matias
- Pasini Francesco
- Pasini Franceso
- Passuello Nicola
- Pattyn Paul
- Pavlov Vasil
- Peeters Renu R Bahadoer Koen C M J
- Pellino Gianluca
- Pennings Alexander J
- Pereira Ricardo
- Perez Daniel
- Perez Rodrigo O
- Perivoliotis Konstantinos
- Perrone Gennaro
- Persiani Roberto
- Pesce Antonio
- Petropolou Thalia
- Pezzuto Roberto
- Picciariello Arcangelo
- Picone Emanuele
- Pikūnienė Ingrida
- Pinto Francisca Lima
- Pire-Abaitua Gerardo
- Pirozzolo Giovanni
- Piyadeoğlu Deniz
- Pizarro Aranda María J
- Plastiras Aris
- Pletinckx Pieter
- Polat Fatih
- Polle Sebastiaan W
- Polydorou Adreas
- Porta Andrea
- Poskus Tomas
- Pratschke Johann
- Pringle Heather C M
- Puca Lucia
- Pucciarelli Salvatore
- Qandeel Mahmoud W M
- Quiroga Ignacio Bodega
- Rabadi Alexander
- Ramboiu Stefan Patrascu Sandu D
- Ramsay George
- Rani Pallavi
- Rani Pallavi
- Rauf Hareem
- Rauf Hareem
- Recordare Alfonso
- Reddavid Rossella
- Rega Daniela
- Reudink Muriël
- Ribeiro Marques Sónia M
- Riedl Peter
- Riis Rolf
- Ripoli Maria Cristina
- Ris Frédéric
- Rizzo Gianluca
- Roată Cristian-Ene
- Rodimov Sergey V
- Rodrigues Jarimba Aldo M
- Rodríguez Carlos Sáez-Cazallas
- Rodríguez-Infante Antonio
- Romano Angela
- Rompou Aliki
- Roos Daphne
- Roscio Francesco
- Rosman Camiel
- Rotholtz Nicolas
- Rottoli Matteo
- Ruiz Hernán
- Runau Francois
- Rutegård Martin
- Rutten Harm J T
- Ruíz-García Pablo
- Ryan Jessica
- Rydbeck Daniel
- Saad Ahmad
- Sacchi Matteo M
- Sacchi Matteo M
- Sainz-Hernández Juan C
- Salgado-Nesme Noel
- Salomon Mario
- Sambucci Daniele
- Sammarco Giuseppe
- Sammour Tarik
- Sampietro Gianluca M
- Samsa Mehmet Veysi
- Santacruz Carlos Cerdán
- Santillan Mateo
- Santoro Giulio A
- Sari Ahmet Can
- Sarmah Panchali
- Sarveswaran Janahan
- Sauvain Marc-Olivier
- Scabini Stefano
- Scheurink Lieke
- Schizas Dimitrios
- Schultz Johannes K
- Sebai Amine
- Sebastian Boby
- Segelman Josefin
- Seitinger Gerald
- Semião Miguel
- Septiem Javier García
- Serralta Daniel
- Shaban Mohamed
- Shaikh Shafaque
- Shapiro Joël
- Siaw Oliver
- Sıbıç Osman
- Sica Giuseppe
- Sietses Colin
- Singh Baljit
- Singh Nirbhaibir
- Singh-Ranger Deepak
- Sinibaldi Giovanni
- Siragusa Leandro
- Sivrikoz Emre
- Sjo Ole H
- Sjöström Olle
- Skrovina Matej
- Sköldberg Filip
- Slavchev Mihail
- Slooter Gerrit D
- Smeeing Diederik P J
- Sokolov Manol
- Soler-Silva Álvaro
- Solomon Michael
- Soriero Domenico
- Souadka Amine
- Spinelli Antonino
- Spinelli Antonino
- Spolverato Gaya
- Staffan Maria
- Stefanescu Victor
- Steller Arend G J Aalbers Ernst J
- Stienstra Roxane M
- Stoica Bogdan
- Stoica Bogdan
- Suchkov Igor A
- Sultan Hytham
- Surlin Valeriu M
- Suárez Marta Castro
- Suárez-Sánchez Aida
- Suárez-Sánchez Aida
- Syllaios Athanasios
- Sánchez Lara Juan E
- Sánchez Teresa Rubio
- Sánchez-Guillén Luis
- Sökmen SELMAN
- Tababa Osama W E
- Taha-Mehlitz Stephanie
- Talboom Kevin
- Talsma Aaldert K
- Tamelis Algimantas
- Tamini Nicolò
- Tanase Ioan
- Tanis Pieter J
- Tantoura Mohammad
- Tanzanu Marta
- Tasende-Presedo Marta M
- Tasis Nikolaos
- Taverne Sophie B M
- Tejedor Patricia
- Teras Jüri
- Teras Roland M
- Terra Antonio La
- Tiefenthal Marit
- Tomasicchio Giovanni
- Tomažič Aleš
- Tonchev Pencho
- Toorenvliet Boudewijn R
- Torres María T
- Toso Christian
- Tsimogiannis Konstantinos
- Tuynmann Jurriaan B
- Tzovaras George
- Ubels Sander
- Ugolini Giampaolo
- Uluk Deniz
- Vailas Michail
- Vailati Bruna B
- van Dalsen Annette D
- van den Broek Nathalie E J
- van den Hengel Berber
- van der Burg Sjirk
- van der Zijden Charlène J
- van Gerven Pieter
- van Kessel Charlotte S
- van Praagh Jasper B
- van Schaik Ted G
- van Westreenen Hendrik L
- van Workum Frans
- Vanclooster Patrick
- Vansteenbrugge Louis
- Vasile Mihai
- Venianaki Maria
- Verdaasdonk Emiel G G
- Vergara-Fernández Omar
- Vermaas Maarten
- Verstappen Sonja
- Vignotto Chiara
- Villar Óscar García
- Vittori Laura
- Vles Wouter J
- von Flüe Markus
- Voron Thibault
- Vosbeek Noortje
- Vuagniaux Aurélie
- Vázquez Andrea
- Waqar Usama
- Waqar Usama
- Ward Nicholas
- Warden Claire
- Westerterp Marinke
- Wienholts Kiedo
- Wiering Bastiaan
- Wijma Allard G
- Wildeboer Aurelia C L
- Wolthuis Albert
- Wong Michael P K
- Woods Kayla
- Xenaki Sofia
- Xynos Evangelos
- Yalkın Ömer
- Yanishev Alexey
- Yüksel Osman
- Zabala Jesús Gómez
- Zakaria Andee D
- Zakaria Zaidi
- Zanini Nicola
- Zanus Giacomo
- Zazo Aya
- Zazo Rama
- Zucchella Martino
- Zukanović Goran
- Zwakman Marije
- Çakır Murat
- Özata İbrahim H
- Özgür İlker
- Özkan Ömer Faruk
- Ülgür Hanife Şeyda
- Šantak Goran
- Šimleša Damir
- Šlenfuktas Vygintas
- Žilinskas Justas
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Objective:To develop and validate a prediction model (STOMA score) for 1-year stoma-free survival in patients with rectal cancer (RC) with anastomotic leakage (AL).Background:AL after RC resection often results in a permanent stoma.Methods:This international retrospective cohort study (TENTACLE-Rectum) encompassed 216 participating centres and included patients who developed AL after RC surgery between 2014 and 2018. Clinically relevant predictors for 1-year stoma-free survival were included in uni and multivariable logistic regression models. The STOMA score was developed and internally validated in a cohort of patients operated between 2014 and 2017, with subsequent temporal validation in a 2018 cohort. The discriminative power and calibration of the models' performance were evaluated.Results:This study included 2499 patients with AL, 1954 in the development cohort and 545 in the validation cohort. Baseline characteristics were comparable. One-year stoma-free survival was 45.0% in the development cohort and 43.7% in the validation cohort. The following predictors were included in the STOMA score: sex, age, American Society of Anestesiologist classification, body mass index, clinical M-disease, neoadjuvant therapy, abdominal and transanal approach, primary defunctioning stoma, multivisceral resection, clinical setting in which AL was diagnosed, postoperative day of AL diagnosis, abdominal contamination, anastomotic defect circumference, bowel wall ischemia, anastomotic fistula, retraction, and reactivation leakage. The STOMA score showed good discrimination and calibration (c-index: 0.71, 95% CI: 0.66-0.76).Conclusions:The STOMA score consists of 18 clinically relevant factors and estimates the individual risk for 1-year stoma-free survival in patients with AL after RC surgery, which may improve patient counseling and give guidance when analyzing the efficacy of different treatment strategies in future studies