804 research outputs found
Relationship Between Fiber Cell-Wall Deformations and Longitudinal Growth Strain: A Research Note
The relationship between fiber cell-wall deformations and longitudinal growth strain is investigated in trees of Eucalyptus pilularis Sm. (blackbutt) and Eucalyptus grandis W. Hill ex Maiden (rose gum).In E. pilularis a weak correlation (r = 0.39) was observed between the number of cell-wall deformations in fiber walls adjacent to the second marginal ray cell and field measurements of longitudinal growth strain. However, a similar relationship could not be found in E. grandis
Classical theory of investment: panel cointegration evidence from 13 EU countries
In the realm of macroeconomic theory, it is well established that investment decisions play an instrumental role in the determination of the level of output and employment; nevertheless, little progress has been made in relation to the theoretical aspects of these decisions. This paper, inspired by the classical approach to capital accumulation as well as the Keynesian theory of effective demand, attempts to enhance our empirical understanding of what determines investment decisions by exploring profitability, financial as well as demand factors. In so doing, a âFully Modified OLSâ panel cointegration framework, for a cluster of two distinct groups of EU countries classified as core and the peripheral economies, provides the platform upon which our econometric investigation takes place. The respective evidence generated from the estimation process is in line with the theoretical framework proposed in this paper
Translation and Validation of the Greek Version of the Antipsychotics and Sexual Functioning Questionnaire (ASFQ)
Introduction
Sexual dysfunction in patients with psychoses may be associated with the psychiatric illness itself (negative symptoms, such as apathy, and avolition), comorbid somatic health, psychosocial factors (stigmatization, discrimination), and the use of psychotropic drugs. In Greece, research into the study of antipsychotic-induced sexual dysfunction is not sufficient.
Aim
This study was conducted to translate and validate the Greek version of the Antipsychotics and Sexual Functioning Questionnaire (ASFQ) in a sample of patients receiving antipsychotic treatment.
Methods
A âforward-backward translationâ method was applied. A pilot study was conducted with 15 outpatients with schizophrenia and bipolar disorder under antipsychotics treatment. Patients also completed the âSubjectsâ Response to Antipsychotics (SRA)â questionnaire in order to assess the validity of the ASFQ. The ASFQ and the SRA questionnaire were completed twice within 2 weeks.
Main outcome measures
Reliability (internal consistency and test-retest) and validity were assessed.
Results
The Greek translation of ASFQ was reliable, with excellent internal consistency (Cronbach's a = 0.90 for men and 0.95 for women in both measurements). In addition, the Spearman correlation coefficient was 1 (P< .001) in all Likert-type questions in both assessments. Finally, Spearman correlation coefficients between ASFQ and SRA were moderately positive to strongly positive (between 0.25 and 1) in both assessments, demonstrating moderate to high validity.
Conclusions
The Greek version of the ASFQ has proved to be a reliable and valid clinical instrument, hence it can be used in further studies in the Greek population. Angelaki M, Galanis P, Igoumenou A, et al. Translation and Validation of the Greek Version of the Antipsychotics and Sexual Functioning Questionnaire (ASFQ). J Sex Med 2021;9:100334
Plasma neurofilament light chain protein is not increased in forensic psychiatric populations: a pilot study
Introduction: Neurofilament light chain protein (NfL) is a fluid biomarker of neural injury measurable in cerebrospinal fluid and blood. Patients with different neurodegenerative disorders and mild traumatic brain injury display elevated levels of NfL. However, so far, elevated levels of NfL have not been demonstrated in persons with psychiatric disorders. To our knowledge, the occurrence of NfL in the blood has not previously been studied in persons undergoing forensic psychiatric assessment or persons treated in forensic mental health services. Supposedly, these persons suffer from experiences and conditions with a higher risk of neural injury than other psychiatric patients. Methods: In this pilot study, we investigated plasma levels of NfL in 20 persons undergoing forensic psychiatric assessment and 20 patients at a forensic psychiatric hospital. NfL values were compared with control groups of healthy individuals matched for age and sex. Results: The prevalence of increased NfL in both forensic groups was low and did not differ compared with the controls. However, some persons undergoing forensic psychiatric assessment showed slightly elevated values. Discussion: The slightly elevated values were observed in the group investigated closer in time to the index crime, when elevated NfL levels could be expected to be more prevalent due to acute conditions from the time of the offense. This gives reason to look further into this group
Quantum-mechanical calculation of Stark widths of Ne VII n=3, transitions
The Stark widths of the Ne VII 2s3s-2s3p singlet and triplet lines are
calculated in the impact approximation using quantum-mechanical Convergent
Close-Coupling and Coulomb-Born-Exchange approximations. It is shown that the
contribution from inelastic collisions to the line widths exceeds the elastic
width contribution by about an order of magnitude. Comparison with the line
widths measured in a hot dense plasma of a gas-liner pinch indicates a
significant difference which may be naturally explained by non-thermal Doppler
effects from persistent implosion velocities or turbulence developed during the
pinch implosion. Contributions to the line width from different partial waves
and types of interactions are discussed as well.Comment: 8 pages, 3 figures; accepted by Phys. Rev.
Biophysical Characterization of (Silica-coated) Cobalt Ferrite Nanoparticles for Hyperthermia Treatment
Magnetic hyperthermia is a technique that describes the heating of material through an external magnetic field. Classic hyperthermia is a medical condition where the human body overheats, being usually triggered by a heat stroke, which can lead to severe damage to organs and tissue due to the denaturation of cells. In modern medicine, hyperthermia can be deliberately induced to specified parts of the body to destroy malignant cells. Magnetic hyperthermia describes the way that this overheating is induced and it has the inherent advantage of being a minimal invasive method when compared to traditional surgery methods. This work presents a particle system that offers huge potential for hyperthermia treatments, given its good loss value, i.e., the particles dissipate a lot of heat to their surroundings when treated with an ac magnetic field. The measurements were performed in a low-cost custom hyperthermia setup. Additional toxicity assessments on Jurkat cells show a very low short-term toxicity on the particles and a moderate low toxicity after two days due to the prevalent health concerns towards nanoparticles in organisms
Iron Oxide Nanoparticles in Regenerative Medicine and Tissue Engineering
In recent years, many promising nanotechnological approaches to biomedical research have been developed in order to increase implementation of regenerative medicine and tissue engineering in clinical practice. In the meantime, the use of nanomaterials for the regeneration of diseased or injured tissues is considered advantageous in most areas of medicine. In particular, for the treatment of cardiovascular, osteochondral and neurological defects, but also for the recovery of functions of other organs such as kidney, liver, pancreas, bladder, urethra and for wound healing, nanomaterials are increasingly being developed that serve as scaffolds, mimic the extracellular matrix and promote adhesion or differentiation of cells. This review focuses on the latest developments in regenerative medicine, in which iron oxide nanoparticles (IONPs) play a crucial role for tissue engineering and cell therapy. IONPs are not only enabling the use of non-invasive observation methods to monitor the therapy, but can also accelerate and enhance regeneration, either thanks to their inherent magnetic properties or by functionalization with bioactive or therapeutic compounds, such as drugs, enzymes and growth factors. In addition, the presence of magnetic fields can direct IONP-labeled cells specifically to the site of action or induce cell differentiation into a specific cell type through mechanotransduction
The Effect of Fused 12-Membered Nickel Metallacrowns on DNA and their Antibacterial Activity
The synthesis, characterization and the biological study of a series of Ni(ll)2(carboxylato)2 [12-
MCNi(II)N(shi)2(pko)2-4][12-MCNi(ii)N(sh03(pko)-4] (CH3OH)3(H3O) fused 12-membered metallacrowns with 10 metal ions and commercial available herbicides or anti-inflammatory drugs as carboxylato ligands are
reported. All the compounds have a mixed ligand composition with salicylhydroxamic acid and di-2-pyridylketonoxime
as chelate agents. The compounds construct metallacrown cores {[12-MCNi(n)N(sj02(pko)2-4][12-MCNi(ll)N(shO3(pko)-4]}2+ following the pattern [-Ni-O-N-]4. The neutral decanuclear [Ni(II)(A)]2[12-MCNi(II)N(shi)2(pko)2-4][12-MCNi(II)N(pko)3(pko)-4] fused metallacrown, consists of two [12-MCM(ox)N(ligand)-4] units the {Ni(ll)(A)[12-MCNi(II)N(shi)2(pko)2-4]} and {Ni(II)(A)[12-MCNi(II)N(shi)3(pko)-4]} with 1+ and 1- charge, respectively. Each metallacrown unit has four ring Ni(II) ions and one additional encapsulated Ni(II) ion in planar arrangement. The anionic unit is bonded with cationic one creating binuclear moieties. The herbicide or antiiflammatory carboxylato ligands are bridging the central octahedral nickel atom with a ring metal ion
in a bindetate fashion. The effect on DNA and their antibacterial activity was examined. The changes in the
mobility can be attributed to the altered structures of the pDNA treated with Ni(II) complexes. Evaluating the
data of the antibacterial activity of the compounds tested, we can conclude that nickel complexes present
strong antibacterial activity
Electrocatalytic oxidation of methanol by the [Ru3O(OAc)6(py)2(CH3OH)] 3+ cluster: improving the metal-ligand electron transfer by accessing the higher oxidation states of a multicentered system
The [Ru3O(Ac)6(py)2(CH3OH)] + cluster provides an effective electrocatalytic species for the oxidation of methanol under mild conditions. This complex exhibits characteristic electrochemical waves at -1.02, 0.15 and 1.18 V, associated with the Ru3III,II,II/Ru3III,III,II/Ru 3III,III,III /Ru3IV,III,III successive redox couples, respectively. Above 1.7 V, formation of two RuIV centers enhances the 2-electron oxidation of the methanol ligand yielding formaldehyde, in agreement with the theoretical evolution of the HOMO levels as a function of the oxidation states. This work illustrates an important strategy to improve the efficiency of the oxidation catalysis, by using a multicentered redox catalyst and accessing its multiple higher oxidation states331020462050CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTĂFICO E TECNOLĂGICO - CNPQCOORDENAĂĂO DE APERFEIĂOAMENTO DE PESSOAL DE NĂVEL SUPERIOR - CAPESFUNDAĂĂO DE AMPARO Ă PESQUISA DO ESTADO DE SĂO PAULO - FAPESPSem informaçãoSem informaçãoSem informaçã
Magnetization of polydisperse colloidal ferrofluids: Effect of magnetostriction
We exploit magnetostriction in polydisperse ferrofluids in order to generate
nonlinear responses, and apply a thermodynamical method to derive the desired
nonlinear magnetic susceptibility. For an ideal gas, this method has been
demonstrated to be in excellent agreement with a statistical method. In the
presence of a sinusoidal ac magnetic field, the magnetization of the
polydisperse ferrofluid contains higher-order harmonics, which can be extracted
analytically by using a perturbation approach. We find that the harmonics are
sensitive to the particle distribution and the degree of field-induced
anisotropy of the system. In addition, we find that the magnetization is higher
in the polydisperse system than in the monodisperse one, as also found by a
recent Monte Carlo simulation. Thus, it seems possible to detect the size
distribution in a polydisperse ferrofluid by measuring the harmonics of the
magnetization under the influence of magnetostriction.Comment: 23 pages, 4 figures. To be accepted for publication in Phys. Rev.
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