12 research outputs found

    Psychological Protection of Population in Social and Legal Aspects

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    The article deals with social and socio-psychological preconditions (which refer to the spheres of demographical development, socialization of children and young people, psychological safety of citizens and so on), for the perfection of normative and legal basis of psychological and socio-psychological assistance to the population of Russia on federal and regional levels. The opinions of experts, the international legal practice in this sphere and also the corresponding experience of Moscow and the project of the Federal Law of the Russian Federation «About the psychological assistance to the population of the Russian Federation» are studied. On the basis of the analysis of this problem the analysis of the project of the regional law «About the state system of psychological assistance in Saint-Petersburg», worked out by one of the authors of this article, was presented. Detailed argumentation of the necessity to pass this law in order to improve socio-psychological climate in Saint-Petersburg in correspondence with the conception of the forestalling law creation is presented and also the grounding of the necessity to pass the Federal Law of the Russian Federation about the psychological assistance taking into account the experience of Belorussia is given

    OPPORTUNITIES FOR PUBLIC ADMINISTRATION REGULATION TOOLS TO INCREASE THE SUSTAINABILITY OF TERRITORIAL DEVELOPMENT

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    The purpose of this study is to identify the opportunities for using mechanisms of state participation in the sustainable territorial development. The authors of the article associate the achievement of sustainable development with the possibility of using various mechanisms of public administration. The authors see the main direction of the application of state mechanisms in sustainable development as ensuring the uniformity of the development of territories. The authors consider the need to equalize the socio-economic situation of the regions to be an important condition for the sustainable development of both individual territories and entire countries. The authors conclude that the state is the main stakeholder and performer in leveling the socio-economic condition of the territories

    Экологическая культура политического восприятия глобальных природоохранных проблем

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    The article discusses the theoretical and methodological problems of actively developing in modern conditions ecological culture, determining its place in the system of humanities. The growing importance of new conception of scientific research and sociocultural practices in the context of the global problems of our time is determined.It is necessary to know the experts’ opinion which environmental problems are being identified as most significant. Only afterwards we can find the ways to solve them. Thereby based on the analysis of materials of the Russian scientific-practical conference with international participation “Environmental protection as a factor of the socio-economic development of municipalities: experience and problems” (2017, Rostov-on-Don, Kurgan), and the results of the Russian expert opinion research conducted by scientists of Rostov scientific elitological school it was concluded that there is an objective necessity to create a unified structure of natural resource management and environmental protection in territorial entities (Vorontsov, Mamychev, Ponedelkov, Yanguzin and Vildanov, 2017; Ponedelkov, Starostin, Mamychev, Grigoryan and Verenich, 2018). At the same time, the prerequisites and trends, the problematic aspects of the development of environmentally-oriented processes in modern Russian conditions determine that the organization of an effective environmental protection policy as a factor of socio-economic development and mechanisms of the implementation its strategic goals in the field of environmental development existing public administration system is possible only if appropriate conditions are created for the dynamic development of the system of environmental education and upbringing, as well as the necessity of developing the implementation of a new civilizational paradigm as a new eco-human behavioral paradigmEl artículo discute los problemas teóricos y metodológicos de desarrollar activamente en las condiciones modernas la cultura ecológica, determinando su lugar en el sistema de humanidades. Se determina la importancia creciente de la nueva concepción de la investigación científica y las prácticas socioculturales en el contexto de los problemas globales de nuestro tiempo.Es necesario conocer la opinión de los expertos sobre qué problemas ambientales se están identificando como los más significativos. Solo después podremos encontrar las formas de resolverlos. De este modo, se basa en el análisis de los materiales de la conferencia científico-práctica rusa con participación internacional "La protección del medio ambiente como factor del desarrollo socioeconómico de los municipios: experiencia y problemas" (2017, Rostov-on-Don, Kurgan), y el Los resultados de la investigación de expertos rusos realizada por científicos de la escuela científica elitológica de Rostov concluyeron que existe una necesidad objetiva de crear una estructura unificada de gestión de recursos naturales y protección ambiental en entidades territoriales (Vorontsov, Mamychev, Ponedelkov, Yanguzin y Vildanov, 2017; Ponedelkov, Starostin, Mamychev, Grigoryan y Verenich, 2018). Al mismo tiempo, los prerrequisitos y las tendencias, los aspectos problemáticos del desarrollo de procesos orientados al medio ambiente en las condiciones modernas de Rusia determinan que la organización de una política de protección ambiental efectiva como un factor del desarrollo socioeconómico y los mecanismos de implementación sean estratégicos. objetivos en el campo del desarrollo ambiental El sistema de administración pública existente solo es posible si se crean las condiciones adecuadas para el desarrollo dinámico del sistema de educación y educación ambiental, así como la necesidad de desarrollar la implementación de un nuevo paradigma de civilización como un nuevo eco. -el paradigma del comportamiento humano.Экологические интересы, выступая одной из материализованных предпосылок человеческой деятельности являются также и показателем качества жизни, уровня развитости общественной морали, правовой культуры общества. В современных политических условиях первостепенное значение имеет институциализация экологических интересов в трех основных секторах общества – государство, сфера производства, общественность (в любой последовательности, но обязательно при наличии этих трех компонентов). В этом контексте интерес представляет как свойство определенной социальной общности, отдельного индивида или группы и выступает в качестве одного из самых существенных факторов, воздействующих на поведение этих социальных единиц в экологической среде, так, и определяющих их наиболее существенные поведенческие акции. и социокультурных практик в контексте глобальных проблем современности.Для установления болевых точек и определения путей решения экологических проблем необходимо знать мнение экспертов о том, какие из этих проблем волнуют людей в наибольшей степени. В связи с этим, на основе анализа материалов Всероссийской научно-практической конференции с международным участием «Защита окружающей среды как фактор социально-экономического развития территорий муниципальных образований: опыт и проблемы» (2017 год, Ростов-на-Дону, Курган), а также результатов общероссийского экспертного опроса, проведенного учеными Ростовской научной элитологической школы, были сделаны о том, что объективно назрела необходимость в создании единой структуры природоресурсного и природоохранного регулирования в территориальных образованиях. В то же время предпосылки и тенденции, проблемные аспекты развития эколого-ориентированных процессов в современных российских условиях таковы, что формирование эффективной политики защиты окружающей среды, рассматриваемой как фактор социально-экономического развития и механизмов реализации ее стратегических целей в области экологического развития в рамках функционирования действующей системы государственного управления, возможно только при создании соответствующих условий для динамичного развития системы экологического образования и воспитания, как и необходимость разработки осуществления новой цивилизационной парадигмы в качестве новой поведенческой парадигмы эко-человека в целом.В статье рассматриваются теоретико-методологические проблемы активно развивающейся в современных условиях экологической культуры, определения ее места в системе гуманитарного знания. Определено все возрастающее значение этого нового представления научных исследовани

    Destructive motivation of personnel: a case study of Russian commercial companies

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    International audienceThe article analyzes the results of an empirical study of the causes of destructive motivation of personnel in Russian commercial organizations. The study was conducted by questioning two hundred employees of commercial organizations in Moscow. The purpose of the research is to reveal the opinion of employees on the causes of destructive motivation of personnel and measures for their elimination. The empirical study revealed the influence of organizational factors on the existence of destructive personnel motivation in organizations, such as: labor organization; remuneration system, benefits and career management; control over the activities of employees; group communications and organizational culture. The study revealed the impact of personal characteristics of employees on destructive motivation. In the course of the survey, the degree of influence of various groups of reasons on the demotivation of employees in the studied commercial organizations was revealed, as well as on the micro-political motivation of employees. In the course of the questionnaire, assessments of the main forms of destructive behavior were obtained, which allowed for developing more detailed recommendations for limiting this negative phenomenon. The practical significance of the research is the results of an analysis of various factors of the internal environment of the organization and the personal characteristics of employees that are significant for the formation of destructive motivation of employees of Russian companies in a transitional economy

    Intraoperative Assessment of Breast Cancer Tissues after Breast-Conserving Surgery Based on Mapping the Attenuation Coefficients in 3D Cross-Polarization Optical Coherence Tomography

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    Intraoperative differentiation of tumorous from non-tumorous tissue can help in the assessment of resection margins in breast cancer and its response to therapy and, potentially, reduce the incidence of tumor recurrence. In this study, the calculation of the attenuation coefficient and its color-coded 2D distribution was performed for different breast cancer subtypes using spectral-domain CP OCT. A total of 68 freshly excised human breast specimens containing tumorous and surrounding non-tumorous tissues after BCS was studied. Immediately after obtaining structural 3D CP OCT images, en face color-coded attenuation coefficient maps were built in co-(Att(co)) and cross-(Att(cross)) polarization channels using a depth-resolved approach to calculating the values in each A-scan. We determined spatially localized signal attenuation in both channels and reported ranges of attenuation coefficients to five selected breast tissue regions (adipose tissue, non-tumorous fibrous connective tissue, hyalinized tumor stroma, low-density tumor cells in the fibrotic tumor stroma and high-density clusters of tumor cells). The Att(cross) coefficient exhibited a stronger gain contrast of studied tissues compared to the Att(co) coefficient (i.e., conventional attenuation coefficient) and, therefore, allowed improved differentiation of all breast tissue types. It has been shown that color-coded attenuation coefficient maps may be used to detect inter- and intra-tumor heterogeneity of various breast cancer subtypes as well as to assess the effectiveness of therapy. For the first time, the optimal threshold values of the attenuation coefficients to differentiate tumorous from non-tumorous breast tissues were determined. Diagnostic testing values for Att(cross) coefficient were higher for differentiation of tumor cell areas and tumor stroma from non-tumorous fibrous connective tissue: diagnostic accuracy was 91–99%, sensitivity—96–98%, and specificity—87–99%. Att(co) coefficient is more suitable for the differentiation of tumor cell areas from adipose tissue: diagnostic accuracy was 83%, sensitivity—84%, and specificity—84%. Therefore, the present study provides a new diagnostic approach to the differentiation of breast cancer tissue types based on the assessment of the attenuation coefficient from real-time CP OCT data and has the potential to be used for further rapid and accurate intraoperative assessment of the resection margins during BCS

    Fight Corruption at the State and Municipal Levels in Russia: Following Sociological (Field) Researches

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    The need to improve the efficiency of combating corruption presupposes an increase in the influence of ethical and moral norms on the observance of prohibitions, restrictions, and requirements established in order to counter corruption, as well as the development of additional mechanisms and tools for preventing corruption manifestations. Moreover, it is clearly not enough to legalize the norms of anti-corruption behaviour, through which law enforcement activities in this area could provide real results. Anti-corruption norms require not only legalization, but also legitimation, that is, recognition and support by citizens and society of this work as a whole. Only a combination of these two components can ensure an increase in the effectiveness of the prevention of corruption offenses in the Russian Federation. Legislative and law enforcement activities in the field of combating corruption systematically demonstrate not resistance, but a compromise, which negatively affects the authority of state bodies responsible for solving problems in the field of combating corruption, provokes legal nihilism among some citizens, disbelief in the goals and objectives declared by the anti-corruption policy

    Growth Kinetics of the (110) Faces of Complex Potassium Cobalt–Nickel Sulphate K2CoxNi1−x(SO4)2·6H2O Crystals

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    The normal growth rate, the steepness of polygonized growth hillocks and the velocity of step movement on the (110) faces of potassium cobalt–nickel sulphate crystals in aqueous solutions with cobalt to nickel ratios of 1:1 and 1:2 were investigated as a function of supersaturation by the geometry of growth hillocks using laser interferometry. It was found that the morphologies of growth hillocks on the (110) faces of the crystals grown from 1:1 and 1:2 solutions are similar and that the growth hillocks are formed by multiple screw dislocation sources. The experimental data on the growth kinetics of the (110) faces of the crystals were analyzed by using the Burton–Cabrera–Frank theory. It was found that (1) there is a critical supersaturation for the growth of the (110) faces, and the value of this supersaturation in the 1:2 solution is higher than that in the 1:1 solution, and (2) the kinetic coefficient of the step movement in the sectors of growth hillocks is highly anisotropic, and the values of this coefficient are larger in 1:2 solution than in 1:1 solution. These results are discussed in the presented work

    Nonlinear Elasticity Assessment with Optical Coherence Elastography for High-Selectivity Differentiation of Breast Cancer Tissues

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    Soft biological tissues, breast cancer tissues in particular, often manifest pronounced nonlinear elasticity, i.e., strong dependence of their Young’s modulus on the applied stress. We showed that compression optical coherence elastography (C-OCE) is a promising tool enabling the evaluation of nonlinear properties in addition to the conventionally discussed Young’s modulus in order to improve diagnostic accuracy of elastographic examination of tumorous tissues. The aim of this study was to reveal and quantify variations in stiffness for various breast tissue components depending on the applied pressure. We discussed nonlinear elastic properties of different breast cancer samples excised from 50 patients during breast-conserving surgery. Significant differences were found among various subtypes of tumorous and nontumorous breast tissues in terms of the initial Young’s modulus (estimated for stress < 1 kPa) and the nonlinearity parameter determining the rate of stiffness increase with increasing stress. However, Young’s modulus alone or the nonlinearity parameter alone may be insufficient to differentiate some malignant breast tissue subtypes from benign. For instance, benign fibrous stroma and fibrous stroma with isolated individual cancer cells or small agglomerates of cancer cells do not yet exhibit significant difference in the Young’s modulus. Nevertheless, they can be clearly singled out by their nonlinearity parameter, which is the main novelty of the proposed OCE-based discrimination of various breast tissue subtypes. This ability of OCE is very important for finding a clean resection boundary. Overall, morphological segmentation of OCE images accounting for both linear and nonlinear elastic parameters strongly enhances the correspondence with the histological slices and radically improves the diagnostic possibilities of C-OCE for a reliable clinical outcome

    Diagnostic Accuracy of Cross-Polarization OCT and OCT-Elastography for Differentiation of Breast Cancer Subtypes: Comparative Study

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    The possibility to assess molecular-biological and morphological features of particular breast cancer types can improve the precision of resection margin detection and enable accurate determining of the tumor aggressiveness, which is important for treatment selection. To enable reliable differentiation of breast-cancer subtypes and evaluation of resection margin, without performing conventional histological procedures, here we apply cross-polarization optical coherence tomography (CP-OCT) and compare it with a novel variant of compressional optical coherence elastography (C-OCE) in terms of the diagnostic accuracy (Ac) with histological verification. The study used 70 excised breast cancer specimens with different morphological structure and molecular status (Luminal A, Luminal B, Her2/Neo+, non-luminal and triple-negative cancer). Our first aim was to formulate convenient criteria of visual assessment of CP-OCT and C-OCE images intended (i) to differentiate tumorous and non-tumorous tissues and (ii) to enable more precise differentiation among different malignant states. We identified such criteria based on the presence of heterogeneities and characteristics of signal attenuation in CP-OCT images, as well as the presence of inclusions/mosaic structures combined with visually feasible assessment of several stiffness grades in C-OCE images. Secondly, we performed a blinded reader study of the Ac of C-OCE versus CP-OCT, for delineation of tumorous versus non-tumorous tissues followed by identification of breast cancer subtypes. For tumor detection, C-OCE showed higher specificity than CP-OCT (97.5% versus 93.3%) and higher Ac (96.0 versus 92.4%). For the first time, the Ac of C-OCE and CP-OCT were evaluated for differentiation between non-invasive and invasive breast cancer (90.4% and 82.5%, respectively). Furthermore, for invasive cancers, the difference between invasive but low-aggressive and highly-aggressive subtypes can be detected. For differentiation between non-tumorous tissue and low-aggressive breast-cancer subtypes, Ac was 95.7% for C-OCE and 88.1% for CP-OCT. For differentiation between non-tumorous tissue and highly-aggressive breast cancers, Ac was found to be 98.3% for C-OCE and 97.2% for CP-OCT. In all cases C-OCE showed better diagnostic parameters independently of the tumor type. These findings confirm the high potential of OCT-based examinations for rapid and accurate diagnostics during breast conservation surgery
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