Transforming the Publishing Academy: How Moving Online and Focusing on Diversity and Inclusion Made Scholarly Publishing Support More Accessible to Graduate Students

Academic libraries frequently offer general research support services such as literature searching and citation management workshops for graduate students, however specific scholarly communications topics such as writing for an academic publication are less frequently addressed (Gannon-Leary & Bent, 2010; Perini & Calcagno, 2013). Support for scholarly publishing, data management and other scholarly communication topics are increasingly needed, and are the type of challenges with which librarians can assist. The University of Louisville Libraries in collaboration with the Graduate School offer a biennial, interdisciplinary, five-week publishing academy for graduate students. The Publishing Academy is designed to introduce students to the scholarly publishing landscape and offer practical tips for writing and publishing in peer-reviewed journals. The first week of the academy is an introduction to the academy with the librarians leading the effort along with a tenured faculty panel discussion about academic publishing; the second week is focused on selecting a journal for one’s publication and covers topics such as copyright and open access as well as journal metrics; the third week covers writing for a publication; the fourth week is an early career (pre-tenure) and non-tenure track faculty panel discussion, and the last week is a wrap-up and a discussion about current issues in scholarly publishing. In Spring 2021, the Publishing Academy moved to an online format due to COVID, and was enhanced with diversity, equity and inclusion (DEI) content. In addition to the general overview of the publishing academy and the content and format of each session, the presenters will discuss the opportunities and challenges associated with moving an in-person program to a fully virtual format, and purposefully integrating DEI into the academy. We will share student feedback, lessons learned from the experiences, and changes we will make to the future academies. By the end of the presentation, the attendees will be able to list potential topics to cover, identify campus partnerships, reflect on how to integrate DEI into programming, and outline the potential steps for the development or enhancement of a similar program on their campus

Diversifying the Publishing Academy: Increasing Access to Scholarly Publishing Education for Graduate Students

Introduction: This article highlights the importance of providing accessible scholarly publishing education and support to graduate students by presenting a case study of how the University of Louisville’s Publishing Academy was modified to be fully online and intentionally focused on diversity, equity, and inclusion (DEI). Literature Review: The literature review examines existing scholarship related to publishing support for graduate students, focusing on literature discussing the importance of publishing for doctoral students and describing successful publishing and writing support programs. Overview of Publishing Academy: University of Louisville’s Publishing Academy is a biennial scholarly publishing program for graduate students founded in 2016. Planning and execution of the spring 2021 iteration of the Academy occurred during the global COVID-19 pandemic and during a time of national civil unrest due to racial inequity and injustice. The context of the times necessitated changes to the Publishing Academy, including moving the Academy to a fully virtual format and intentionally focusing on DEI in developing Academy sessions and faculty panels. Next Steps: Next steps for the Publishing Academy are considered based on participant feedback and organizers’ observations

What to Expect: Medical Quality Outcomes and Achievements of a Multidisciplinary Inpatient Musculoskeletal System Rehabilitation

The incidence of chronic diseases is rising. Rehabilitation plays a vital role in preventing and minimizing the functional limitations associated with chronic conditions and aging. Routine outcome measures include disease-specific and unspecific general health parameters. This study evaluates indicators for medical quality outcomes from 10,373 patients (61.00 ± 13.65 years, 51.7% women) who have undergone orthopedic rehabilitation for three weeks. Inpatient rehabilitation reduces lifestyle-related risk factors, optimizes organ functioning and improves the well-being in the majority of patients (81.3%; SMD = 0.52 ± 0.38). Improvements of unspecific and indication specific outcome parameters can be observed in a comparable magnitude. However, disease specific and unspecific health factors are not directly related to each other (r = 0.19). Age, gender, ICD-classification and time of rehabilitation have an influence on initial values and on indication-specific medical outcomes but are insignificant with regards to improvements in unspecific medical outcome parameters. Inpatient rehabilitation includes two main pathways of medical practice, which can be clearly distinguished in terms of their therapeutic outcome. There are general health interventions, such as lifestyle modifications, diet and physical exercise, and symptom-specific treatments. So multidisciplinary medical rehabilitation improves general well-being and physical functioning as well as reduces risk factors in the majority of patients

Navigationsbilder im World Wide Web

Wie in gedruckten Lehr-/Lernmaterialien werden auch in Online-Lehr-/Lernmaterialien Bilder eingesetzt. Viele dieser Bilder sind Navigationsbilder, die der Navigation im Hypertext dienen. Ist es möglich, die Funktion dieser Bilder für den Text näher zu bestimmen? Dieses könnte zu einer Einschätzung dessen beitragen, wie und inwieweit diese Bilder das Lernen der Inhalte unterstützen. Wir stellen ein Klassifikationsschema von Navigationsbildern vor, das auf der Klassifikation herkömmlicher Bilder nach ihren Funktionen für Texte aufbaut und diese um für die visuellräumliche Wahrnehmung relevante Kriterien erweitert. In einer Untersuchung von im Deutschen Bildungsserver (http://www.bildungsserver.de) verzeichneten Online-Ressourcen wenden wir dieses Klassifikationsschema an. Wir schließen mit einem Ausblick auf Erfolg versprechende Einsatzmöglichkeiten von Navigationsbildern.Like printed teaching materials, online teaching/learning materials employ pictures. Many of these are navigation pictures that help navigation in the material’s hypertext. Is it possible to determine the function of these pictures for the text in more detail? This could contribute to an assessment of how and how much these pictures support the learning of the material’s content. We present a classification scheme for navigation pictures that is based on a classification of the functions of standard pictures for texts. It extends this scheme by criteria that are relevant for visuo-spatial perception. We apply the classification scheme in a study of online resources in the German Educational Resources web server (http://www.bildungsserver.de). We conclude with a discussion of promising ways of employing navigation pictures.Peer Reviewe

Motivations for Adolescent COVID-19 Vaccination: A Comparative Study of Adolescent and Caregiver Perspectives in Germany

Given the crucial role of vaccination in halting the COVID-19 pandemic, it is imperative to understand the factors that motivate adolescents to get vaccinated. We surveyed adolescents and their accompanying guardians scheduled to receive a COVID-19 vaccination (Comirnaty) in an urban region in Germany in mid-2021 regarding their motivation for getting vaccinated and collected data on their sociodemographic characteristics, medical history, vaccination status, and any history of COVID-19 infection in the family. We also queried information strategies related to the SARS-CoV-2 pandemic. Motivations for getting vaccinated were similar among adolescents and their parents. The primary reasons for vaccination were protection against SARS-CoV-2-related illness and gaining access to leisure facilities. This was not influenced by gender, health status, migration background, or the presence of chronic or acute diseases. The percentage of parents who had received SARS-CoV-2 immunization and the proportion of parents with a high level of education were higher among study participants than in the general population. Adolescents were especially willing to be vaccinated if they came from a better educational environment and had a high vaccination rate in the family. Emphasizing the importance of vaccination among all segments of the population and removing barriers to vaccines may lead to an ameliorated acceptance of COVID-19 vaccines

StrainGE: A toolkit to track and characterize low-abundance strains in complex microbial communities

Human-associated microbial communities comprise not only complex mixtures of bacterial species, but also mixtures of conspecific strains, the implications of which are mostly unknown since strain level dynamics are underexplored due to the difficulties of studying them. We introduce the Strain Genome Explorer (StrainGE) toolkit, which deconvolves strain mixtures and characterizes component strains at the nucleotide level from short-read metagenomic sequencing with higher sensitivity and resolution than other tools. StrainGE is able to identify strains at 0.1x coverage and detect variants for multiple conspecific strains within a sample from coverages as low as 0.5x

Jowett’s Thucydides: A corpus-based analysis of translation as political intervention

Thucydides’ History of the Peloponnesian War is a key text in the classical Greek canon and an important source of insights into the structures and tensions at the heart of ancient Athenian democracy. Consequently, modern interpretations of his analysis have repeatedly played a major role in shaping debates on the viability and desirability of democratic rule. This paper aims to build on previous discussion of Benjamin Jowett's 1881 translation of Thucydides by applying a comparative corpus-based methodology to explore how this translator's own personal politics shaped his re-presentation of this text. The analysis reveals a striking emphasis on the position and activity of democratic leaders throughout Jowett’s version, strongly consistent with the ideology of leadership that he developed during his career as Master of Balliol College, Oxford

Morbillivirus Glycoprotein Expression Induces ER Stress, Alters Ca2+ Homeostasis and Results in the Release of Vasostatin

Although the pathology of Morbillivirus in the central nervous system (CNS) is well described, the molecular basis of neurodegenerative events still remains poorly understood. As a model to explore Morbillivirus-mediated CNS dysfunctions, we used canine distemper virus (CDV) that we inoculated into two different cell systems: a monkey cell line (Vero) and rat primary hippocampal neurons. Importantly, the recombinant CDV used in these studies not only efficiently infects both cell types but recapitulates the uncommon, non-cytolytic cell-to-cell spread mediated by virulent CDVs in brain of dogs. Here, we demonstrated that both CDV surface glycoproteins (F and H) markedly accumulated in the endoplasmic reticulum (ER). This accumulation triggered an ER stress, characterized by increased expression of the ER resident chaperon calnexin and the proapoptotic transcription factor CHOP/GADD 153. The expression of calreticulin (CRT), another ER resident chaperon critically involved in the response to misfolded proteins and in Ca2+ homeostasis, was also upregulated. Transient expression of recombinant CDV F and H surface glycoproteins in Vero cells and primary hippocampal neurons further confirmed a correlation between their accumulation in the ER, CRT upregulation, ER stress and disruption of ER Ca2+ homeostasis. Furthermore, CDV infection induced CRT fragmentation with re-localisation of a CRT amino-terminal fragment, also known as vasostatin, on the surface of infected and neighbouring non-infected cells. Altogether, these results suggest that ER stress, CRT fragmentation and re-localization on the cell surface may contribute to cytotoxic effects and ensuing cell dysfunctions triggered by Morbillivirus, a mechanism that might potentially be relevant for other neurotropic viruses

The genome of Onchocerca volvulus, agent of river blindness

Human onchocerciasis is a serious neglected tropical disease caused by the filarial nematode Onchocerca volvulus that can lead to blindness and chronic disability. Control of the disease relies largely on mass administration of a single drug, and the development of new drugs and vaccines depends on a better knowledge of parasite biology. Here, we describe the chromosomes of O. volvulus and its Wolbachia endosymbiont. We provide the highest-quality sequence assembly for any parasitic nematode to date, giving a glimpse into the evolution of filarial parasite chromosomes and proteomes. This resource was used to investigate gene families with key functions that could be potentially exploited as targets for future drugs. Using metabolic reconstruction of the nematode and its endosymbiont, we identified enzymes that are likely to be essential for O. volvulus viability. In addition, we have generated a list of proteins that could be targeted by Federal-Drug-Agency-approved but repurposed drugs, providing starting points for anti-onchocerciasis drug development