1,902 research outputs found
Determination of gas temperature in the plasmatron channel according to the known distribution of electronic temperature
An analytical method to calculate the temperature distribution of heavy
particles in the channel of the plasma torch on the known distribution of the
electronic temperature has been proposed. The results can be useful for a
number of model calculations in determining the most effective conditions of
gas blowing through the plasma torch with the purpose of heating the heavy
component. This approach allows us to understand full details about the
heating of cold gas, inpouring the plasma, and to estimate correctly the
distribution of the gas temperature inside the channel
Mistletoe lectin dissociates into catalytic and binding subunits before translocation across the membrane to the cytoplasm
AbstractHybridomas producing monoclonal antibodies (mAbs) against the mistletoe lectin A-chain (MLA) were obtained to investigate the intracellular routing and translocation of ribosome-inactivating proteins. Anti-MLA mAb MNA5 did not bind the holotoxin but interacted with isolated MLA. This epitope was not recognized upon MLA denaturation or conjugation of MLA with the ricin binding subunit (RTB). Furthermore, the mAbs did not appreciably react with a panel of MLA synthetic octapeptides linked to the surface of polyethylene pins. A study of the cytotoxicity of mistletoe lectin, ricin, and chimeric toxin MLA/RTB for the hybridomas revealed that interchain disulfide bond reduction and subunit dissociation are required for cytotoxic activity of mistletoe lectin
Modeling of GERDA Phase II data
The GERmanium Detector Array (GERDA) experiment at the Gran Sasso underground
laboratory (LNGS) of INFN is searching for neutrinoless double-beta
() decay of Ge. The technological challenge of GERDA is
to operate in a "background-free" regime in the region of interest (ROI) after
analysis cuts for the full 100kgyr target exposure of the
experiment. A careful modeling and decomposition of the full-range energy
spectrum is essential to predict the shape and composition of events in the ROI
around for the search, to extract a precise
measurement of the half-life of the double-beta decay mode with neutrinos
() and in order to identify the location of residual
impurities. The latter will permit future experiments to build strategies in
order to further lower the background and achieve even better sensitivities. In
this article the background decomposition prior to analysis cuts is presented
for GERDA Phase II. The background model fit yields a flat spectrum in the ROI
with a background index (BI) of cts/(kgkeVyr) for the enriched BEGe data set and
cts/(kgkeVyr) for the
enriched coaxial data set. These values are similar to the one of Gerda Phase I
despite a much larger number of detectors and hence radioactive hardware
components
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Modeling of GERDA Phase II data
The GERmanium Detector Array (Gerda) experiment at the Gran Sasso underground laboratory (LNGS) of INFN is searching for neutrinoless double-beta (0νββ) decay of 76Ge. The technological challenge of Gerda is to operate in a “background-free” regime in the region of interest (ROI) after analysis cuts for the full 100 kg·yr target exposure of the experiment. A careful modeling and decomposition of the full-range energy spectrum is essential to predict the shape and composition of events in the ROI around Qββ for the 0νββ search, to extract a precise measurement of the half-life of the double-beta decay mode with neutrinos (2νββ) and in order to identify the location of residual impurities. The latter will permit future experiments to build strategies in order to further lower the background and achieve even better sensitivities. In this article the background decomposition prior to analysis cuts is presented for Gerda Phase II. The background model fit yields a flat spectrum in the ROI with a background index (BI) of 16.04+0.78−0.85⋅10−3 cts/(keV·kg·yr) for the enriched BEGe data set and 14.68+0.47−0.52⋅10−3 cts/(keV·kg·yr) for the enriched coaxial data set. These values are similar to the one of Phase I despite a much larger number of detectors and hence radioactive hardware components
Final Results of GERDA on the Two-Neutrino Double-β Decay Half-Life of 76Ge
We present the measurement of the two-neutrino double-
β
decay rate of
76
Ge
performed with the GERDA Phase II experiment. With a subset of the entire GERDA exposure, 11.8 kg yr, the half-life of the process has been determined:
T
2
ν
1
/
2
=
(
2.022
±
0.01
8
stat
±
0.03
8
syst
)
×
10
21
yr
. This is the most precise determination of the
76
Ge
two-neutrino double-
β
decay half-life and one of the most precise measurements of a double-
β
decay process. The relevant nuclear matrix element can be extracted:
M
2
ν
eff
=
(
0.101
±
0.001
)
Search for tri-nucleon decays of ^{76}Ge in GERDA
We search for tri-nucleon decays of 76Ge in the dataset from the GERmanium Detector Array (GERDA) experiment. Decays that populate excited levels of the daughter nucleus above the threshold for particle emission lead to disintegration and are not considered. The ppp-, ppn-, and pnn-decays lead to 73Cu, 73Zn, and 73Ga nuclei, respectively. These nuclei are unstable and eventually proceed by the beta decay of 73Ga to 73Ge (stable). We search for the 73Ga decay exploiting the fact that it dominantly populates the 66.7 keV 73mGa state with half-life of 0.5 s. The nnn-decays of 76Ge that proceed via 73mGe are also included in our analysis. We find no signal candidate and place a limit on the sum of the decay widths of the inclusive tri-nucleon decays that corresponds to a lower lifetime limit of 1.2×1026 yr (90% credible interval). This result improves previous limits for tri-nucleon decays by one to three orders of magnitude
Search for exotic physics in double-β decays with GERDA Phase II
A search for Beyond the Standard Model double- decay modes ofGe has been performed with data collected during the Phase II of theGERmanium Detector Array (GERDA) experiment, located at Laboratori Nazionalidel Gran Sasso of INFN (Italy). Improved limits on the decays involvingMajorons have been obtained, compared to previous experiments with Ge,with half-life values on the order of 10 yr. For the first time withGe, limits on Lorentz invariance violation effects in double-decay have been obtained. The isotropic coefficient, which embeds Lorentz violation indouble- decay, has been constrained at the order of GeV. Wealso set the first experimental limits on the search for light exotic fermionsin double- decay, including sterile neutrinos.<br
Liquid argon light collection and veto modeling in GERDA Phase II
The ability to detect liquid argon scintillation light from within a densely packed high-purity germanium detector array allowed the Gerda experiment to reach an exceptionally low background rate in the search for neutrinoless double beta decay of 76 Ge. Proper modeling of the light propagation throughout the experimental setup, from any origin in the liquid argon volume to its eventual detection by the novel light read-out system, provides insight into the rejection capability and is a necessary ingredient to obtain robust background predictions. In this paper, we present a model of the Gerda liquid argon veto, as obtained by Monte Carlo simulations and constrained by calibration data, and highlight its application for background decomposition
Final Results of GERDA on the Two-Neutrino Double- Decay Half-Life of Ge
We present the measurement of the two-neutrino double- decay rate of
Ge performed with the GERDA Phase II experiment. With a subset of the
entire GERDA exposure, 11.8 kgyr, the half-life of the process has been
determined: yr. This is the most precise determination of the
Ge two-neutrino double- decay half-life and one of the most
precise measurements of a double- decay process. The relevant nuclear
matrix element can be extracted: Comment: 7 pages, 4 figures, 2 table
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