Haematological and genotoxic profile study of workers exposed to medical waste

Objective: To evaluate the haematological and genotoxic profile of workers exposed to medical waste. Method: Descriptive study of an observational nature, performed with two distinct groups: exposed (20 individuals) and unexposed (20 individuals), which had blood samples collected for analysis. Results: The results revealed an increased erythrocytes, hematocrit and leukocytes of the exposed group compared to the unexposed group. In the group exposed were identified: eosinophilia (45%), atypical lymphocytes (35%) and neutrophil toxic granulation (25%). It revealed a significant genotoxic effect by the content and frequency of major damage in the exposed group. There was no correlation of these results with the habits and life styles reported. Conclusion: It was found that the study group might be undergoing reaction processes caused by some agent, as well as genetic instability. These data highlight the need for greater biomonitoring of these workers in order to prevent neoplastic conditions

Haematological and genotoxic profile study of workers exposed to medical waste

Objective: To evaluate the haematological and genotoxic profile of workers exposed to medical waste. Method: Descriptive study of an observational nature, performed with two distinct groups: exposed (20 individuals) and unexposed (20 individuals), which had blood samples collected for analysis. Results: The results revealed an increased erythrocytes, hematocrit and leukocytes of the exposed group compared to the unexposed group. In the group exposed were identified: eosinophilia (45%), atypical lymphocytes (35%) and neutrophil toxic granulation (25%). It revealed a significant genotoxic effect by the content and frequency of major damage in the exposed group. There was no correlation of these results with the habits and life styles reported. Conclusion: It was found that the study group might be undergoing reaction processes caused by some agent, as well as genetic instability. These data highlight the need for greater biomonitoring of these workers in order to prevent neoplastic conditions. Descriptors: Medical Waste, Waste Collectors, Occupational Risk

Haematological and genotoxic profile study of workers exposed to medical waste

Objective: To evaluate the haematological and genotoxic profile of workers exposed to medical waste. Method: Descriptive study of an observational nature, performed with two distinct groups: exposed (20 individuals) and unexposed (20 individuals), which had blood samples collected for analysis. Results: The results revealed an increased erythrocytes, hematocrit and leukocytes of the exposed group compared to the unexposed group. In the group exposed were identified: eosinophilia (45%), atypical lymphocytes (35%) and neutrophil toxic granulation (25%). It revealed a significant genotoxic effect by the content and frequency of major damage in the exposed group. There was no correlation of these results with the habits and life styles reported. Conclusion: It was found that the study group might be undergoing reaction processes caused by some agent, as well as genetic instability. These data highlight the need for greater biomonitoring of these workers in order to prevent neoplastic conditions. Descriptors: Medical Waste, Waste Collectors, Occupational Risk

Tratamento cirúrgico da hiperplasia condilar: relato de caso clínico / Surgical treatment of condilar hyperplasia: clinical case report

INTRODUÇÃO: A hiperplasia do côndilo mandibular (HCM) é conhecida como uma malformação de crescimento incomum, não neoplásica e caracterizada pelo crescimento e alargamento excessivo do côndilo mandibular uni ou bilateral, geralmente autolimitada, sem predileção por gênero ou raça, acometendo pacientes entre 11 e 30 anos de idade, com etiologia desconhecida e ainda motivo de muita discussão na literatura. O tratamento geralmente é multidisciplinar entre fisioterapia, ortodontia e cirurgia. OBJETIVO: O objetivo do trabalho é um relatar um caso clínico em que foi realizado condilectomia proporcional, discopexia ipsilateral a HCM e cirurgia ortognática bimaxilar para correção da assimetria facial decorrente da HCM.. CONCLUSÃO: Para o correto tratamento da HCM é de extrema importância o diagnóstico preciso para que se possa delinear o tratamento ideal. Como técnica cirúrgica a condilectomia proporcional mostra-se como um tratamento promissor, principalmente por estar aliada com a tecnologia onde é possível ofertar um tratamento personalizado e com excelente previsibilidade, além de poder evitar um tratamento secundário com cirurgia ortognática

Haematological and genotoxic profile study of workers exposed to medical waste

Objective: To evaluate the haematological and genotoxic profile of workers exposed to medical waste. Method: Descriptive study of an observational nature, performed with two distinct groups: exposed (20 individuals) and unexposed (20 individuals), which had blood samples collected for analysis. Results: The results revealed an increased erythrocytes, hematocrit and leukocytes of the exposed group compared to the unexposed group. In the group exposed were identified: eosinophilia (45%), atypical lymphocytes (35%) and neutrophil toxic granulation (25%). It revealed a significant genotoxic effect by the content and frequency of major damage in the exposed group. There was no correlation of these results with the habits and life styles reported. Conclusion: It was found that the study group might be undergoing reaction processes caused by some agent, as well as genetic instability. These data highlight the need for greater biomonitoring of these workers in order to prevent neoplastic conditions. Descriptors: Medical Waste, Waste Collectors, Occupational Risk

Draft genome sequences of two species of "difficult-to-Identify" human-pathogenic Corynebacteria: implications for better identification tests

Submitted by Alexandre Sousa ([email protected]) on 2015-11-06T22:55:03Z No. of bitstreams: 1 v03p0082.pdf: 276850 bytes, checksum: af34e737e8172c99d64f6cbef0051b18 (MD5)Approved for entry into archive by Alexandre Sousa ([email protected]) on 2015-11-06T23:27:25Z (GMT) No. of bitstreams: 1 v03p0082.pdf: 276850 bytes, checksum: af34e737e8172c99d64f6cbef0051b18 (MD5)Made available in DSpace on 2015-11-06T23:27:25Z (GMT). No. of bitstreams: 1 v03p0082.pdf: 276850 bytes, checksum: af34e737e8172c99d64f6cbef0051b18 (MD5) Previous issue date: 2015Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, Brasil.Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Rio de Janeiro, RJ, Brasil.Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, Brasil.Universidade Federal do Pará. Instituto de Ciências Biológicas. Belém, PA, Brasil.Universidade Federal do Pará. Instituto de Ciências Biológicas. Belém, PA, Brasil / Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Laboratório de Referência Nacional para Doenças dos Animais Aquáticos. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Laboratório de Referência Nacional para Doenças dos Animais Aquáticos. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Laboratório de Referência Nacional para Doenças dos Animais Aquáticos. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Laboratório de Referência Nacional para Doenças dos Animais Aquáticos. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Laboratório de Referência Nacional para Doenças dos Animais Aquáticos. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Laboratório de Referência Nacional para Doenças dos Animais Aquáticos. Belo Horizonte, MG, Brasil.Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Departamento de Microbiologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Controle de Qualidade em Saúde. Departamento de Microbiologia. Rio de Janeiro, RJ, Brasil.Institut Pasteur. Unité de Prévention et Thérapie Moléculaires des Maladies Humaines. Paris, France.Institut Pasteur. Unité de Prévention et Thérapie Moléculaires des Maladies Humaines. Paris, France.Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Rio de Janeiro, RJ, Brasil.Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Belo Horizonte, MG, Brasil.Universidade Federal do Pará. Instituto de Ciências Biológicas. Belém, PA, Brasil.Universidade Federal do Pará. Instituto de Ciências Biológicas. Belém, PA, Brasil.Non-diphtheriae Corynebacterium species have been increasingly recognized as the causative agents of infections in humans. Differential identification of these bacteria in the clinical microbiology laboratory by the most commonly used biochemical tests is challenging, and normally requires additional molecular methods. Herein, we present the annotated draft genome sequences of two isolates of “difficult-to-identify” human-pathogenic corynebacterial species: C. xerosis and C. minutissimum. The genome sequences of ca. 2.7 Mbp, with a mean number of 2,580 protein encoding genes, were also compared with the publicly available genome sequences of strains of C. amycolatum and C. striatum. These results will aid the exploration of novel biochemical reactions to improve existing identification tests as well as the development of more accurate molecular identification methods through detection of species-specific target genes for isolate's identification or drug susceptibility profiling

Sampling completeness changes perceptions of continental scale climate–species richness relationships in odonates

Aim: Insects are one of the least studied taxa, with most species lacking basic ecological and biogeographical information. This problem is particularly acute in the tropics, where low sampling effort hampers accurate estimates of species richness at scale and potentially confounds efforts to identify the drivers of biogeographical gradients. Here, we evaluate the quality of the data on the distribution and diversity of odonate species in the Neotropics, while also examining the influence of sampling completeness on climate–richness relationships using a comprehensive database of odonates. Location: The Neotropics. Taxon: Odonata. Methods: Using 56,535 records collected from 1970 to 2021, we assess whether climate–species richness models vary under different scenarios of survey completeness. Results: Our survey compilation revealed that most Neotropical diversity of Odonata likely remains unknown. Only 1% of the one-degree cells covering the Neotropics held reliable information on odonate species richness, with particularly severe gaps in the Caribbean, Central America, northeastern Brazil and northern Chile. Temperature, precipitation and potential evapotranspiration exert consistent effects on Odonata richness across the entire Neotropics, regardless the level of survey completeness. Whereas seasonality-related variables are less important predictors of species richness at the biogeographical scale. Main Conclusions: By highlighting areas where inventories are more reliable and identifying regions that require increased data collection efforts and mobilization, our assessment offers a roadmap for improving the reliability of odonate inventories in the Neotropics. Furthermore, our findings underscore the importance of accounting for varying levels of survey completeness in macroecological models to reveal robust climate–species richness relationships. Simultaneously, they highlight strong climatic predictors of species richness, irrespective of survey effort intensity. These predictors provide a solid foundation for modelling and predicting odonate species richness in the Neotropics.Fil: Alves Martins, Fernanda. Centro de Investigación en Biodiversidades y Recursos Energético; Portugal. Universidad de Porto; PortugalFil: Stropp, Juliana. Museo Nacional de Ciencias Naturales; EspañaFil: Juen, Leandro. Universidade Federal do Pará; BrasilFil: Ladle, Richard J.. Universidad de Porto; Portugal. Centro de Investigación en Biodiversidades y Recursos Energético; PortugalFil: Lobo, Jorge M.. Museo Nacional de Ciencias Naturales; EspañaFil: Martinez Arribas, Javier. Centro de Investigación en Biodiversidades y Recursos Energético; PortugalFil: Marco Júnior, Paulo De. Universidade Federal de Goiás; BrasilFil: Schlemmer Brasil, Leandro. Universidade Federal Do Mato Grosso;Fil: Ferreira, Victor Rennan Santos. Universidade Federal do Pará; BrasilFil: Bastos, Rafael Costa. Universidade Federal do Pará; BrasilFil: Córdoba Aguilar, Alex. Universidad Nacional Autónoma de México; MéxicoFil: Medina Espinoza, Emmy Fiorella. Universidade Federal do Pará; BrasilFil: Dutra, Silvia Viviana. Universidade Federal do Norte do Tocantins; BrasilFil: Vilela, Diogo Silva. Universidade Estadual Paulista Julio de Mesquita Filho; BrasilFil: Cordero Rivera, Adolfo. Universidad de Vigo; EspañaFil: del Palacio, Alejandro. Universidad Nacional de Avellaneda; ArgentinaFil: Ramírez, Alonso. North Carolina State University; Estados UnidosFil: Carvalho Soares, Anderson André. Universidade Federal do Pará; BrasilFil: Farias, Antonio Bruno Silva. Universidade Federal de Sergipe; BrasilFil: Resende, Bethânia Oliveira de. Universidade Federal do Pará; BrasilFil: Santos, Bruna dos. Universidade de Sao Paulo; BrasilFil: Bota Sierra, Cornelio A.. Universidad de Antioquia; Colombia. University of Alabama at Birmingahm; Estados UnidosFil: Mendoza Penagos, Cristian Camilo. Universidade Federal do Pará; BrasilFil: Veras, Daniel Silas. Universidade Federal do Pará; BrasilFil: Pessacq, Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Centro de Investigación Esquel de Montaña y Estepa Patagónica. Universidad Nacional de la Patagonia "San Juan Bosco". Centro de Investigación Esquel de Montaña y Estepa Patagónica; ArgentinaFil: Miguel, Thiago Barros. Instituto Federal de Educação Ciências e Tecnologia de Mato Grosso; BrasilFil: Mendes, Thiago Pereira. Universidade Estadual do Maranhão; BrasilFil: Neiss, Ulisses Gaspar. Instituto Nacional de Pesquisas da Amazônia; Brasil. Instituto de Criminalística; BrasilFil: Almeida, Wanessa Rejane de. Universidade Federal de Sergipe; BrasilFil: Hortal, Joaquín. Museo Nacional de Ciencias Naturales; España. Universidade Federal de Goiás; Brasi

Global impact of the first coronavirus disease 2019 (COVID-19) pandemic wave on vascular services

This online structured survey has demonstrated the global impact of the COVID-19 pandemic on vascular services. The majority of centres have documented marked reductions in operating and services provided to vascular patients. In the months during recovery from the resource restrictions imposed during the pandemic peaks, there will be a significant vascular disease burden awaiting surgeons. One of the most affected specialtie

The PLATO Mission

International audiencePLATO (PLAnetary Transits and Oscillations of stars) is ESA's M3 mission designed to detect and characterise extrasolar planets and perform asteroseismic monitoring of a large number of stars. PLATO will detect small planets (down to <2 R_(Earth)) around bright stars (<11 mag), including terrestrial planets in the habitable zone of solar-like stars. With the complement of radial velocity observations from the ground, planets will be characterised for their radius, mass, and age with high accuracy (5 %, 10 %, 10 % for an Earth-Sun combination respectively). PLATO will provide us with a large-scale catalogue of well-characterised small planets up to intermediate orbital periods, relevant for a meaningful comparison to planet formation theories and to better understand planet evolution. It will make possible comparative exoplanetology to place our Solar System planets in a broader context. In parallel, PLATO will study (host) stars using asteroseismology, allowing us to determine the stellar properties with high accuracy, substantially enhancing our knowledge of stellar structure and evolution. The payload instrument consists of 26 cameras with 12cm aperture each. For at least four years, the mission will perform high-precision photometric measurements. Here we review the science objectives, present PLATO's target samples and fields, provide an overview of expected core science performance as well as a description of the instrument and the mission profile at the beginning of the serial production of the flight cameras. PLATO is scheduled for a launch date end 2026. This overview therefore provides a summary of the mission to the community in preparation of the upcoming operational phases