193 research outputs found

    Leggere il teatro

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    The theatrical work of Maddalena Mazzocut-Mis, published in the volume Teatro da leggere. Mito e conflitto – with the accompaniment of detailed premises by the author herself – develops in two directions. The first one, looking at the past, leads to the rewriting of works of the literary tradition according to a new point of view. The reworking of famous classical characters relates the distant with the near, allowing us to reflect, among other things, on the function and value of illusions. The second, looking at the present, leads to the presentation of seemingly insignificant characters to highlight the tragic fate of rise and fall or desperate search for a recognized identity

    La historia de la ciencia como herramienta para la enseñanza de física en secundaria : un ejemplo en calor y temperatura

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    In this work we suggest and analyze some stages of a course on heat and temperature which knowledge of the past of the ideas and the solution provided can enable a better understanding of the content. The hypothesis that guided the planning of activities was that the scientific content studied throughout its history comes closer to the cognitive universe, not only of the student, but of man himself

    Lineage-specific interface proteins match up the cell cycle and differentiation in embryo stem cells.

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    The shortage of molecular information on cell cycle changes along embryonic stem cell (ESC) differentiation prompts an in silico approach, which may provide a novel way to identify candidate genes or mechanisms acting in coordinating the two programs. We analyzed germ layer specific gene expression changes during the cell cycle and ESC differentiation by combining four human cell cycle transcriptome profiles with thirteen in vitro human ESC differentiation studies. To detect cross-talk mechanisms we then integrated the transcriptome data that displayed differential regulation with protein interaction data. A new class of non-transcriptionally regulated genes was identified, encoding proteins which interact systematically with proteins corresponding to genes regulated during the cell cycle or cell differentiation, and which therefore can be seen as interface proteins coordinating the two programs. Functional analysis gathered insights in fate-specific candidates of interface functionalities. The non-transcriptionally regulated interface proteins were found to be highly regulated by post-translational ubiquitylation modification, which may synchronize the transition between cell proliferation and differentiation in ESCs

    Innovative technique for the base isolation of existing buildings

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    An innovative base isolation system has been recently proposed for the retrofitting of existing buildings, in which the isolation layer is inserted under the building foundations so that the building, along with its foundations, is isolated from the surrounding soil. The isolation layer resides in closely-spaced micro-tunnels, constructed under the entire width of the building. These micro-tunnels, along with the trenches around the building, isolate the structure from the surrounding soil. The execution of these micro-tunnels is the most critical construction stage, because it may result in settlements which can damage the structure. In this paper, the behaviour of an existing structure, consisting of a masonry wall subjected to tunnelling-induced ground subsidence, is analysed. A parametric study is conducted using 2-D nonlinear finite element analyses to understand the role of key factors such as strength and stiffness of soil and masonry, roughness of soil-structure interface, excavation sequence of tunnels, wall dimensions and openings configuration. The study identifies the design variables which influence the most the risk of structural damage and suggests the most effective damage symptoms to be monitored during constructio

    Identificazione dinamica sperimentale di edifici strategici sotto sisma

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    Edifici pubblici quali ospedali, scuole, chiese e municipi costituiscono un patrimonio di importanza strategica per la vita di una comunità. La loro gestione richiede un periodico monitoraggio delle condizioni di sicurezza sia a breve che a lungo termine che può oggi essere condotto in modo efficace ed oggettivo mediante sistemi automatici e permanenti di misura delle vibrazioni strutturali. All'occorrenza di un evento sismico, tali sistemi hanno il merito di cogliere l'effettivo comportamento dinamico della struttura, permettendo la calibrazione sperimentale di modelli numerici, utili per una accurata valutazione del livello di sicurezza sismico e per la progettazione di interventi migliorativi. In quest'ottica assume particolare rilievo la rete di monitoraggio dinamico permanente di edifici strategici realizzata dal Dipartimento di Protezione Civile. Quattro di questi edifici sono stati scelti come casi studio allo scopo di analizzarne la risposta acquisita durante il recente evento sismico del Gennaio 2012 in Lunigiana/Garfagnana. Il presente articolo riporta i risultati della caratterizzazione dinamica condotta su uno di essi: il municipio di San Romano in Garfagnana (LU

    Innovative technique for the base isolation of existing buildings

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    An innovative base isolation system has been recently proposed for the retrofitting of existing buildings, in which the isolation layer is inserted under the building foundations so that the building, along with its foundations, is isolated from the surrounding soil. The isolation layer resides in closely-spaced micro-tunnels, constructed under the entire width of the building. These micro-tunnels, along with the trenches around the building, isolate the structure from the surrounding soil. The execution of these micro-tunnels is the most critical construction stage, because it may result in settlements which can damage the structure. In this paper, the behaviour of an existing structure, consisting of a masonry wall subjected to tunnelling-induced ground subsidence, is analysed. A parametric study is conducted using 2-D nonlinear finite element analyses to understand the role of key factors such as strength and stiffness of soil and masonry, roughness of soil-structure interface, excavation sequence of tunnels, wall dimensions and openings configuration. The study identifies the design variables which influence the most the risk of structural damage and suggests the most effective damage symptoms to be monitored during constructio
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