Skeletal Muscle Mass Indices in Healthy Young Mexican Adults Aged 20–40 Years: Implications for Diagnoses of Sarcopenia in the Elderly Population

Background and Objectives. Skeletal muscle and skeletal muscle indices in young adults from developing countries are sparse. Indices and the corresponding cut-off points can be a reference for diagnoses of sarcopenia. This study assessed skeletal muscle using dual-energy X-ray absorptiometry (DXA) in healthy male and female subjects aged 20–40 years and compared their appendicular skeletal muscle mass (ASM) and total-body skeletal muscle (TBSM) indices using certain cut-off points published in the literature. Methods. A sample of 216 healthy adults men and women from northwest Mexico was included. Body composition was assessed by DXA and several published DXA-derived skeletal muscle indices were compared. Results. Both, ASM and TBSM were higher in men compared to the women group (23.0 ± 3.4 versus 15.9 ± 1.6 kg; P<0.05 and 26.5 ± 4.1 versus 16.9 ± 1.9 kg; P<0.05, resp.). These differences were also valid for both indices. When derived cut-off points were compared with the most reported indices, significant differences were found. Interpretation and Conclusion. Published cut-off points from Caucasians are higher than cut-off point derived in this sample of Mexican subjects. The new DXA-derived cut-off points for ASM proposed herein may improve diagnoses of sarcopenia in the geriatric Mexican population

Aplicación del algoritmo lompen a los problemas Fm | prmu | Cmac y Fm | block | Cmax

In this paper we face the permutation flow-shop scheduling problem with a makespan objective function in two variants, with and without storage space between machines. We use an improved branch and bound algorithm, suitable for parallel computation, to solve these problems, and auxiliary heuristics to attain an initial good solution. The auxiliary heuristics proposed are built by two steps: in the first step a permutation is obtained; in the second step a local search procedure is applied. The improvement obtained by the local search procedure on NEH heuristic as first step is shown. Since the flow-shop scheduling problem with storage space is a relaxation of the problem without storage space, some elements and procedures developed for that problem can be used in both problems. In particular, some bounding procedures, for instance Nabeshima or Lageweg bounding schema, can be adapted. Moreover, the reversibility property holds on both problems. Consequently the branch and bound algorithm can be applied simultaneously to the direct and the inverse instances. The same sets of data are submitted to heuristics and to the double branch-and-bound algorithm, LOMPEN, assuming first they are instances of flow-shop scheduling problem with storage space and later they are instances of flow-shop scheduling problem without storage space. The algorithms are coded in a similar way; therefore the behaviour and performance can be compared

SISTEMA DE GESTIÓN DE INFORMACIÓN REFERENTE A LA EVALUACIÓN NUTRICIONAL DE LAS PERSONAS CON VIH-SIDA EN LA PROVINCIA CIEGO DE ÁVILA

En el departamento de Dietética y Servicios de la Dirección Provincial de Salud, una de las gestiones que se realiza es la referente a la Evaluación Nutricional de los Personas con VIH-SIDA en la Provincia Ciego de Ávila. Este proceso es bastante engorroso, hasta hoy se realiza manualmente y se almacena en fichas de papel que se deterioran con el tiempo, así como no es posible acceder a la información almacenada de forma rápida y eficiente en el momento que se necesita. El presente trabajo propone un sistema informático a partir del empleo de bases de datos y tecnología Web, para contribuir a disminuir las insuficiencias. Para su diseño se utiliza el lenguaje de modelado UML y la metodología de desarrollo RUP. Se muestran las etapas de Análisis (Modelo del Dominio, Requisitos, Actores, Paquetes, Diagrama de Casos de Uso y Estudio de Factibilidad), Implementación y Prueba del sistema (Descripción de los Casos de Uso, Principios de Diseño, Diseño de la Base de Datos, Diagrama de Despliegue y Diagrama de Componentes, la Descripción de los Procedimientos de Prueba y los Casos de Uso de Prueba). Se implementa en el lenguaje de programación libre Personal Home Page (PHP), que posibilita su uso en cualquier plataforma y se utiliza como gestor de Base de Datos MySql, que garantiza la seguridad y protección requerid

Metal-free visible light-promoted synthesis of isothiazoles: a catalytic approach for N-S bond formation from iminyl radicals under batch and flow conditions

A sustainable synthesis of isothiazoles has been developed using an α-amino-oxy acid auxiliary and applying photoredox catalysis. This simple strategy features mild conditions, broad scope and wide functional group tolerance representing a new enviromentally friendly option to prepare these highly valuable heterocycles. Furthermore, the synthetic value of the method is highlighted by the preparation of a natural product derivative and the implementation of the reaction in a continuous flow setupWe acknowledge the financial support by the Spanish Government (RTI2018-095038-B-I00) and ERC (ERC-CG, 647550

Body fat measurement by bioelectrical impedance and air displacement plethysmography: a cross-validation study to design bioelectrical impedance equations in Mexican adults

<p>Abstract</p> <p>Background</p> <p>The study of body composition in specific populations by techniques such as bio-impedance analysis (BIA) requires validation based on standard reference methods. The aim of this study was to develop and cross-validate a predictive equation for bioelectrical impedance using air displacement plethysmography (ADP) as standard method to measure body composition in Mexican adult men and women.</p> <p>Methods</p> <p>This study included 155 male and female subjects from northern Mexico, 20–50 years of age, from low, middle, and upper income levels. Body composition was measured by ADP. Body weight (BW, kg) and height (Ht, cm) were obtained by standard anthropometric techniques. Resistance, R (ohms) and reactance, Xc (ohms) were also measured. A random-split method was used to obtain two samples: one was used to derive the equation by the "all possible regressions" procedure and was cross-validated in the other sample to test predicted versus measured values of fat-free mass (FFM).</p> <p>Results and Discussion</p> <p>The final model was: FFM (kg) = 0.7374 * (Ht²/R) + 0.1763 * (BW) - 0.1773 * (Age) + 0.1198 * (Xc) - 2.4658. R²was 0.97; the square root of the mean square error (SRMSE) was 1.99 kg, and the pure error (PE) was 2.96. There was no difference between FFM predicted by the new equation (48.57 ± 10.9 kg) and that measured by ADP (48.43 ± 11.3 kg). The new equation did not differ from the line of identity, had a high R²and a low SRMSE, and showed no significant bias (0.87 ± 2.84 kg).</p> <p>Conclusion</p> <p>The new bioelectrical impedance equation based on the two-compartment model (2C) was accurate, precise, and free of bias. This equation can be used to assess body composition and nutritional status in populations similar in anthropometric and physical characteristics to this sample.</p

Greater male variability in daily energy expenditure develops through puberty

The authors also gratefully acknowledge funding from the Chinese Academy of Sciences (grant no. CAS153E11KYSB20190045) to J.R.S. and the US National Science Foundation (grant no. BCS-1824466) awarded to H.P. Acknowledgements Yvonne Schönbeck provided important information about morphometric measurements for Dutch children. A chat over dinner with Karsten Koehler, Eimear Dolan and Danny Longman brought up a number of thoughts that influenced this manuscript. The DLW database, which can be found at https://doublylabelled-waterdatabase.iaea.org/home, is hosted by the IAEA and generously supported by Taiyo Nippon Sanso and SERCON. We are grateful to the IAEA and these companies for their support and especially to Takashi Oono for his tremendous efforts at fundraising on our behalf.Peer reviewedPublisher PD

Greater male variability in daily energy expenditure develops through puberty

There is considerably greater variation in metabolic rates between men than between women, in terms of basal, activity and total (daily) energy expenditure (EE). One possible explanation is that EE is associated with male sexual characteristics (which are known to vary more than other traits) such as musculature and athletic capacity. Such traits might be predicted to be most prominent during periods of adolescence and young adulthood, when sexual behaviour develops and peaks. We tested this hypothesis on a large dataset by comparing the amount of male variation and female variation in total EE, activity EE and basal EE, at different life stages, along with several morphological traits: height, fat free mass and fat mass. Total EE, and to some degree also activity EE, exhibit considerable greater male variation (GMV) in young adults, and then a decrease in the degree of GMV in progressively older individuals. Arguably, basal EE, and also morphometrics, do not exhibit this pattern. These findings suggest that single male sexual characteristics may not exhibit peak GMV in young adulthood, however total and perhaps also activity EE, associated with many morphological and physiological traits combined, do exhibit GMV most prominently during the reproductive life stages