Proposal of a stochastic model to determine the bibliometric variables influencing the quality of a journal: application to the field of Dentistry

On the basis of the Impact Factor of Journal Citation Reports developed by ISI as a journal quality indicator, this paper puts forth an ordinal regression model to estimate the journal’s position by terciles. The set of explanatory variables includes the H-index of its Editor-in-chief, percentage of papers published in the journal that received external funding, average number of papers published yearly, and two factors concerning the scope and structure of the journal. The proposed model was applied to the field of Dentistry, Oral Surgery and Medicine, and led us to the conclusion that the above mentioned covariables alone had a significant input in the model, but not the factors. The essay performed on a sample of 30 Dentistry journals included in JCR provided a confirmatory correct classification rate (CCR) of 80%, with a predictive CCR of 75% on a sample of eight new journals not previously considered in the phase of model estimation.Proyect MTM2017-88708-P of f Secretaría de Estado de Investigación, Desarrollo e Innovación, Ministerio de Economía y Competitividad de Españ

Collagen Matrix vs. Autogenous Connective Tissue Graft for Soft Tissue Augmentation: A Systematic Review and Meta-Analysis

This work was supported by: (1) the Ministry of Economy and Competitiveness and European Regional Development Fund [Project MAT2017-85999-P MINECO/AEI/FEDER/UE], (2) University of Granada/Regional Government of Andalusia Research Fund from Spain and European Regional Development Fund (A-BIO-157-UGR-18/FEDER). This research is part of C.V.'s PhD research study.Soft tissues have been shown to be critical for the maintenance of both teeth and implants. Currently, regenerative soft tissue techniques propose the use of collagen matrices, which can avoid the drawbacks derived from the obtainment of autogenous tissue graft. A systematic review and meta-analysis were conducted to ascertain the efficacy of collagen matrices (CM) compared to autogenous connective tissue graft (CTG) to improve soft tissue dimensions. An electronic and manual literature searches were performed to identify randomized clinical trials (RCT) or controlled clinical trials (CCT) that compared CTG and CM. Pooled data of width of keratinized tissue (KT) and mucosal thickness (MT) were collected and weighted means were calculated. Heterogeneity was determined using Higgins (I-2). If I-2 > 50% a random-effects model was applied. Nineteen studies were included based on the eligibility criteria. When using CTG a higher MT gain (0.32 mm, ranging from 0.49 to 0.16 mm) was obtained than when employing CM. Similar result was obtained for the width of KT gain, that was 0.46 mm higher (ranging from 0.89 to 0.02 mm) when employing CTG. However, it can be stated that, although autogenous CTG achieves higher values, CM are an effective alternative in terms of total width of KT and MT gain.Ministry of Economy and Competitiveness MAT2017-85999-P MINECO/AEI/FEDER/UEEuropean Commission MAT2017-85999-P MINECO/AEI/FEDER/UE A-BIO-157-UGR-18/FEDERUniversity of Granada/Regional Government of Andalusia Research Fund from Spai

Antibiofilm Activity of Diclofenac and Antibiotic Solutions in Endodontic Therapy

Introduction: The aim of this study was to compare the antibiofilm effects of a triple antibiotic solution (TAS); a double antibiotic solution (DAS); and 5%, 2.5%, and 1.25% diclofenac solutions (DCSs) against Enteroccocus faecalis biofilm. Methods: Eighty-four sterile radicular dentin blocks were used as biofilm substrate for 3 weeks. The study groups were as follows: (1) 1 mg/mL TAS (minocycline, metronidazole, and ciprofloxacin), (2) 1 mg/mL DAS (metronidazole and ciprofloxacin), (3) 5% DCS, (4) 2.5% DCS, (5) 1.25% DCS, and (6) 0.9% saline solution. The antimicrobial activity was evaluated by bacterial count determinations and confocal laser scanning microscopy. The contact time for the antimicrobial tests was 5 minutes. Bacterial counts were expressed as the reduction percentage of colony-forming units; for the confocal laser scanning microscopic evaluation, the log10 total biovolume and percentage of green population (live cells) were calculated. Results: The colony-forming unit reduction percentage ranged between 62.98 and 98.62, respectively, for TAS and 5% DCS. The DCS showed a concentration-dependent effect.For the confocal laser scanning microscopy, the log10 total biovolume in all groups was very similar and showed a scarce (1.39-1.02) but significant reduction with respect to the control; 5% and 2.5% DCSs gave the lowest viable cell percentage. The TAS and DAS groups showed intermediate values without significant differences between them. Conclusions: DCSs at 5% and 2.5% have greater antimicrobial effects than TAS and DAS and may be considered a valid alternative for controlling the infection of teeth with apical periodontitis.Grupo CTS 16

Dentine tubule disinfection by different irrigation protocols

The purpose of this study was to test the antimicrobial activity and the smear layer removal of different irrigation protocols-sodium hypochlorite (NaOCl), NaOCl followed by ethylenediaminetetraacetic acid (EDTA), and NaOCl combined with etidronic acid (HEBP)-against infected dentine tubules during root canal preparation. Single rooted premolars contaminated with Enterococcus faecalis were chemomechanically prepared. Depending on the irrigation protocols, the roots were divided into the following groups: (1) distilled water during and after instrumentation; (2) 2.5% NaOCl during and after instrumentation; (3) 2.5% NaOCl/9% HEBP during and after instrumentation; and (4) 2.5% NaOCl during instrumentation followed by 17% EDTA after instrumentation. The percentage of dead cells and the biovolume in infected dentine tubules were measured using confocal laser scanning microscopy and the live/dead technique. Smear layer removal on root canal wall surfaces was observed by means of scanning electron microscopy. Results were compared through parametric tests (p .05), followed by the group irrigated with water. All the irrigation protocols-including water-significantly reduced the bacteria biovolume. No dentine tubules free of smear layer were found in the positive control or the 2.5% NaOCl group. With NaOCl/HEBP and NaOCl+EDTA, respectively, 90.41% ± 7.33 and 76.54% ± 15.30 of dentine tubules were free of smear layer (p = .01). NaOCl/HEBP and NaOCl+EDTA exerted an important antimicrobial activity against bacteria inside dentine tubules, lowering the bacteria biovolume and eliminating a high amount of the smear layer, particularly in the NaOCl/HEBP group.Grupo de Investigación CTS 16

Alveolar Bone Ridge Augmentation Using Polymeric Membranes: A Systematic Review and Meta-Analysis

This work was funded by the Ministry of Economy and Competitiveness and European Regional Development Fund (MINECO/FEDER MAT2017-85999P). University of Granada/Regional Government of Andalusia Research Fund from Spain and European Regional Development Fund (A-BIO-157-UGR-18/FEDER). This research is part of M.T-O.'s Ph.D. research study.The data presented in this study are available on request from the corresponding author.Alveolar bone ridge resorption occurred after natural teeth loss and it can restrict the possibility of dental implants placement. The use of bone regenerative procedures is frequently required. The existing evidence regarding the efficacy of horizontal bone ridge augmentation trough guided bone regeneration (GBR) using polymeric membranes was stated. A systematic review and meta-analysis were performed. Electronic and manual literature searches were conducted. Screening process was done using the National Library of Medicine (MEDLINE by PubMed), Embase, and the Cochrane Oral Health. Included articles were randomized controlled trials and observational studies. Weighted means were calculated. Heterogeneity was determined using Higgins (I2). If I2 > 50% a random-effects model was applied. It was found that the mean of horizontal bone gain was 3.95 mm, ranging from 3.19 to 4.70 mm (confidence interval 95%). Heterogeneity is I2 = 99% (confidence interval 95%) and significance of the random-effects model was p < 0.001. The complications rate was 8.4% and membrane exposure was the most frequent. Through this study, we were able to conclude that the existing scientific evidence suggests that GBR using polymeric membranes is a predictable technique for achieving horizontal bone augmentation, thus, permitting a proper further implant placement.Ministry of Economy and Competitiveness MINECO/FEDER MAT2017-85999PEuropean Commission MINECO/FEDER MAT2017-85999P A-BIO-157-UGR-18/FEDERUniversity of Granada/Regional Government of Andalusia Research Fund from Spai

Effectiveness of different therapies for drug-related osteonecrosis of the jaw

Antecedentes. La osteonecrosis de los maxilares asociada a fármacos (ONMAF) es una complicación grave de pacientes oncológicos o con osteoporosis, en tratamiento con fármacos antirresortivos. En el momento actual, no existe evidencia científica ni consenso sobre el enfoque de tratamiento más adecuado en función de las etapas de la ONMAF. Objetivo. Analizar la efectividad de las diferentes opciones terapéuticas en el tratamiento de la ONMAF. Métodos de búsqueda. Se realizó una búsqueda de estudios en las siguientes bases de datos: PubMed (MEDLINE, Cochrane Library), Web of Science (WoS) e índice médico español (IME). Criterios de selección. Estudios con resultados sobre tratamiento de la ONMAF. Análisis de datos. Se realizó una estadística descriptiva considerando medias y porcentajes. Resultados. 52 estudios sobre tratamiento de la ONMAF fueron incluidos en esta revisión. La resolución completa de casos de ONMAF se observó en 205 de 257 pacientes (79.8%) tratados con cirugía más colgajos; 202 de 253 (otro 79.8%) con la suspensión del fármaco antirresortivo (“drug holiday”); 512 de 648 (79.0%) con la cirugía extensa; 41 de 59 (69.5%) con la terapia coadyuvante con oxígeno hiperbárico; 462 de 680 (67.9%) con la cirugía conservadora; 55 de 119 (46.2%) con terapia láser y, finalmente, 100 de los 346 pacientes (28.9%) consiguieron la resolución completa con el tratamiento médico (antibióticos+antisépticos). Conclusiones. Dependiendo de la severidad de las exposiciones óseas, el tratamiento quirúrgico combinado con colgajos, parece ser la mejor opción terapéutica para el tratamiento de la ONMAF.Background. Antiresorptive drug-related osteonecrosis of the jaw (ADRONJ) is a serious complication of cancer patients or osteoporosis, under treatment with antiresorptive drugs. At present, there is no scientific evidence or consensus on the most appropriate treatment approach depending on the stages of the ADRONJ. Objective. To assess the effectiveness of the different therapeutic options in the treatment of ADRONJ. Search methods. The following electronic databases were searched: PubMed (MEDLINE, Cochrane Library), Web of Science (WoS) and Spanish Medical Index (IME). Selection criteria. Studies with results on treatment of ADRONJ. Data analysis. Descriptive statistics were carried out considering means and percentages. Results. 52 studies on treatment of ADRONJ were included in this review. The complete resolution of ADRONJ cases was observed in 205 of 257 patients (79.8%) treated with surgery plus flaps; 202 of 253 (another 79.8%) with the suspension of the antiresorptive drug (“drug holiday”); 512 of 648 (79.0%) with extensive surgery; 41 of 59 (69.5%) with adjuvant hyperbaric oxygen therapy; 462 of 680 (67.9%) with conservative surgery; 55 of 119 (46.2%) with laser therapy and, finally, 100 of the 346 patients (28.9%) achieved complete resolution with medical treatment (antibiotics + antiseptics). Conclusions. Depending on the severity of bone exposures, surgical treatment combined with flaps appears to be the best therapeutic option for the treatment of ADRONJ

Efficacy of local antibiotic therapy in the treatment of peri-implantitis: A systematic review and meta-analysis

This work was supported by: 1) the Ministry of Economy and Competitiveness and European Regional Development Fund [Project PID2020-114694RB-I00]. Funding for open access charge: University of Granada/CBUA.Objectives: The aim of this systematic review and meta-analysis was to state the efficacy of local administration of antibiotics in the treatment of peri-implantitis in terms of peri-implant probing depth (PPD) and bleeding on probing (BoP) reduction. Data, sources and study selection: Electronic and manual literature searches were conducted. Screening process was done using the National Library of Medicine (MEDLINE by PubMed), Embase and the Cochrane Oral Health. Included articles were randomized controlled trials and observational studies. Weighted means were calculated. Heterogeneity was determined using Higgins (I2). Due to the encountered heterogeneity between the studies being combined, random-effects models were applied in order to analyze effect sizes. Twelve studies (365 patients and 463 implants) were included in the systematic review. After peri-implantitis treatment with local antibiotics, PPD was reduced 1.40 mm (95% confidence interval: 0.82-1.98). When local antibiotics were applied, a 0.30 mm higher reduction of PPD was obtained than in the control group (95% confidence interval: 0.07-0.53). BoP attained an odds ratio value of 1.82 (95% confidence interval: 1.09-3.04), indicating that the likehood of bleeding is almost two-fold when antibiotics are not locally administrated. Adverse effects were not found after applying local antibiotics. Conclusions: The local antibiotic administration does reduce, without adverse effects, both peri-implant probing depths and bleeding on probing in patients affected by peri-implantitis, if compared to control groups without local antibiotic application. Clinical significance: Patients with dental implants frequently suffer from peri-implantitis. Clinical features of periimplantitis lesions include the presence of bleeding on probing and increased peri-implant probing depths. Both BoP and PPD have become reduced after local administration of antibiotics.Ministry of Economy and Competitiveness PID2020-114694RB-I00European Commission PID2020-114694RB-I00University of Granada/CBU

Relationship between menopause and periodontal disease: A cross-sectional study in a Portuguese population

Background: Menopause is associated with important systemic and oral changes. Many researchers have tried to evaluate the influence of hormonal changes associated with menopause in the periodontium, however results are contradictory. Objective: Evaluate the possible effects of menopause on the severity of periodontal disease and tooth loss, by considering several general, oral and periodontal parameters. Methods: 102 women with chronic periodontitis, and at least six teeth, were divided into two groups: a study group (SG) consisting of 68 menopausal women and a control group (CG) consisting of 34 premenopausal women. The participants had extensive anamnesis, made by a single senior periodontologist, which collected demographic data, medical and gynaecological history and habits. Additionally, oral and periodontal parameters including: number of teeth, plaque index, presence of calculi, probing depth, bleeding on probing, gingival recession and attachment loss were recorded. The following statistical tests were used: Chi-square, Fisher’s t-test for independent samples, non-parametric Wilcoxon-Mann-Whitney, and linear multiple regression. Results: The number of teeth was significantly lower in postmenopausal women (SG 10.8 ± 5.9, CG 6.8 ± 4.6), however, after adjusting for age, smoking and plaque index, the difference was no longer statistically significant (P=0.169). The attachment loss was slightly higher in the study group, although the difference is not significant (SG 4.31 ± 1.08, CG 4.05 ± 1.28). Conclusions: Menopause does not appear to significantly influence the severity of periodontal disease and tooth loss. Other factors may exert a greater influence on the progression of periodontal disease rather than menopause itself

Periodontal Treatment by Dental Undergraduate Students: Assessment of the Patient’s Oral Quality of Life -A Prospective Pilot Study

Purpose: To assess the impact of nonsurgical periodontal treatment, performed by undergraduate dental students, on oral health-related quality of life of patients with periodontitis. Materials and Methods: An observational, prospective, single-arm cohort study with pre-post test involving 31 undergraduate dental students was performed. A complete periodontal examination was performed before and after receiving nonsurgical periodontal treatment. The main independent clinical variables assessed were the degree of periodontal inflammation and the number of teeth with periodontitis. Oral health-related quality of life was assessed before and after treatment through the Oral Impacts on Daily Performances (OIDP) questionnaire. The association between the extent of periodontal treatment (measured as number of treated teeth) and final OIDP score was assessed, adjusting for age, sex, and baseline OIDP in a multiple regression model. Results: Thirty-four patients were enrolled and treated by the undergraduate students. The mean OIDP value (global absolute score), representing the severity and frequency of the impacts, decreased from 26.2 to 12 after treatment. The mean percentage of impact, representing the number dimensions affected by oral health (global percent score), was reduced from 13% to 6%. However, no association between the number of treated teeth and post-treatment OIDP score was observed after adjusting for age, sex, and baseline OIDP score. Conclusion: Nonsurgical periodontal treatment performed by undergraduate dental students improved the oral health-related quality of life of periodontal patients, although no statistically significant association was found between the extent of periodontal treatment and the final OIDP score.Sin financiación1.256 JCR (2020) Q4, 88/92 Dentistry, Oral Surgery & Medicine0.429 SJR (2020) Q2, 1/1 Dental HygieneNo data IDR 2020UE

Prevention of Occupational Hazards Due to Asbestos Exposure in Dentistry. A Proposal from a Panel of Experts

Asbestos in all its forms is a Group 1 material agent with proven carcinogenic effects in the human being since 1977. Exposure to asbestos can be considered unsafe. The use of asbestos in the field of dentistry had a common use in the manufacture of dental prostheses in the 1960s and 1970s. Taking into account the long induction period of this agent and the plausibility for being a risk factor in dentistry, the objective of this study is to propose a plan for the prevention of occupational risks due to asbestos exposure in dentistry by means of the contribution of a panel of experts. An Expert Panel (EP) approach was used in which a group of nine experts identified and documented the use of asbestos in the dental profession. EP was created and followed the protocol in accordance with the EuropeAid Assessment Guidelines. As a result of this study, EP documented the common use and sources of asbestos in dentistry in prosthetic materials, dental dressings, and in the coating of casting cylinders. EP also created a consensus document on the priority measures for the Plan for the Prevention of Risks from Asbestos in Dentistry, based on previous reports from the European Commission Senior Labour Inspectors' Committee. The document concluded that obtainment of information, receiving specific training on the subject and performing epidemiological studies, and the proper risk assessments were the priority measures to adopt