Sensors integration in additive DMLS metal parts

The fabrication of metal parts by laser-based additive manufacturing (AM) processes is providing many applications in the medical field. The layer-by-layer growth of the component provided by powder micromelting allows, at least in theory, the incorporation of discrete sensors and wires inside the metal material. However, several process-related issues make this operation very challenging. This paper introduces the incorporation of thermal and inertial sensors inside 17-4PH steel specimens fabricated by DMLS (direct metal laser sintering) process (PCT/IB2019/053581, 02/05/2018). In the final configuration, the sensors are totally encased into the continuous metal parts with complete protection against contamination and tampering

Serum triglycerides, but not cholesterol or leptin, are decreased in suicide attempters with mood disorders

BackgroundMany peripheral biomarkers, including low cholesterol and its fractions, have been examined to identify suicidal behavior. Herein, we assessed serum lipid profile and some proteins putatively associated with suicidal behavior in subjects with mood disorder (bipolar disorder or major depressive disorder) with a recent suicide attempt and with no lifetime history of suicide attempts.MethodsFifty subjects had presented an episode of attempted suicide during the last 15 days, and 36 subjects had no history of any suicide attempt. We measured total cholesterol, HDL, LDL and triglycerides as well as serum leptin, brain-derived neurotrophic factor (BDNF), S100B and C-reactive protein (CRP).ResultsIndividuals that had attempted suicide presented decreased body mass index (BMI) and waist circumference. After adjusting for these confounders, we found that triglycerides were decreased in attempted suicide subjects. We found no differences among total cholesterol, LDL, and HDL or leptin, S100B, CRP and BDNF.LimitationsThis is a cross-sectional study, and we cannot therefore assess whether a decrease in triglycerides caused a mood episode with suicidal ideation that led to a suicide attempt or if the presence of a mood episode originated a loss of appetite and consequent loss of weight, therefore decreasing triglyceride levels.ConclusionsThese results do not support the hypothesis that lower levels of cholesterol are associated with suicidal behavior in a mood disorder sample. However, our data support the idea that adiposity is differentiated in these patients (reduced BMI, waist circumference and serum triglycerides), which could lead to an altered communication between the adipose tissue and brain

PROFESSORES DA REDE MUNICIPAL DE ENSINO DE SANTA MARIA/RS: RELATO DE PROCESSO DE FORMAÇÃO CONTINUADA

Esse texto relata a formação de professores realizada durante 2011 e 2012 com docentesde Educação Física cujo objetivo foi contribuir com a elaboração e o desenvolvimento depropostas relacionadas à organização do trabalho pedagógico. Os registros dasformações tiveram como base vídeos, atas, avaliações individuais e coletivas realizadasno término de cada encontro. As análises sinalizam para a continuidade no processo deformação para esses professores visando a autonomia individual e coletiva.Consideramos que a continuidade da formação desloque-se para as próprias escolas,materializando sua centralidade como espaço formativo, a ser constituído organicamentecomo lugar de produção de conhecimento

Analisi e progettazione di un convertitore DC/DC di tipo risonante LLC per il pilotaggio di una stringa di LED

E' stata svolta un'analisi sulla tipologia più adatta a pilotare una stringa di 28 LED bianchi per ottenere altro rendimento ed integrazione magnetica dell'elemento di isolamento galvanico. La scelta si è rivolta ad un converitore risonante di tipo LLC per le caratteristiche di alto rendimento teorico, essendo pilotabile in soft-switching. La progettazione è stata fatta attraverso un'analisi approssimata di prima armonica. E' stato realizzato un prototipo sperimentale per validare i passi di progettazione e simulazion

Análises quali e quantitativas de micotoxinas em águas da cadeia produtiva do arroz por CCD e CCDAE

This study validated a simple and applied method for determining mycotoxins aflatoxin B1, aflatoxin B2, ochratoxin A, zearalenone and deoxynivalenol, in water from the rice production chain. Five solvent combinations for extraction were tested, with quantification performed by TLC/HPTLC and confirmation by LC-MS/MS. Mycotoxins in water from field and rice industries were evaluated. Mycotoxin recovery levels were around 90%. Two samples from rice parboiling waste were contaminated (deoxynivalenol/aflatoxin B1, 110/9 ng mL-1; and deoxynivalenol, 100 ng mL-1). Zearalenone, deoxynivalenol and ochratoxin A (36, 30 and 28%) were carried to soaking water during parboiling