Présentation atypique d’une granulomatose avec polyangeite: à propos d’une observation pédiatrique

La granulomatose avec polyangéite (GPA) est une vascularite nécrosante systémique, caractérisée par une inflammation granulomateuse, une nécrose tissulaire et une vascularite touchant les vaisseaux de moyen et, surtout, de petit calibre, elle touche rarement l'enfant

Porokeratosis: Two Faces, One Family

Porokeratosis is a disorder of keratinisation whose pathogenesis is yet unclear. It has been postulated that it results from the proliferation of an abnormal clone of keratinocytes, triggered by several factors, such as immunosuppression or prolonged ultraviolet exposure. Various clinical forms are recognized whose common denominator is a keratotic ring surrounding a central zone of atrophy. The histological hallmark is the cornoid lamella, a thin column of hyperproliferative abnormal keratinocytes. We describe two cases of porokeratosis. A 67-year-old woman with an erythematous purplish round plaque surrounded by a keratotic border that had appeared 6 years previously on the left sural region was diagnosed as ‘giant’ porokeratosis. A 49-year-old man presented with small papules coalescent in an erythematous oval plaque on the lateral side of the left foot consistent with linear porokeratosis

Karakteristik Bahan Dasar Diesel Cylinder Liner (Dcl)

Kebutuhan Diesel Cylinder Liner(DCL) di Indonesia 114.512 buah DCL/hari untuk mendukung industry transportasi di Indonesia. Kebutuhan DCL yang tinggi tersebut, saat ini suplainya masih didominasi dari luar negeri. Industry pengecoran besi cor local sudah mencoba produksi DCL, akan tetapi kualitas DCL yang dihasilkan masih jauh dari standar. Penelitian ini bertujuan untuk mengetahui karakteristik komposisi kimia, kekerasan brinell, dan struktur mikro dari 3 jenis DCL yang beredar di industry transpotasi yaitu original merk X, tidak original, dan produk pengecoran local, sehingga dapat diketahui kualitas rendah DCL produksi local dikarenakan kualitas bahan atau factor yang lain. Hasil pengujian menunjukkan bahan dasar yang digunakan DCL produksi local menggunakan jenis besi cor yang sama dengan DCL originalya itu besi cor kelabu. Hasil pengujian kekerasan menunjukkan bahwa DCL produksi local memiliki kekerasan tertinggi yaitu 217,9 HBN, sedangkan DCL original dengan DCL tidak original menunjukkan nilai yang hamper sama yaitu 187,6 HBN dan 185,2 HBN. Hasil pengujian menunjukkan bahwa struktur mikro semua jenis DCL menunjukan struktur pearlite dan grafit (bentuk flake dengan orientasi tak beraturan) mendominasi seluruh permukaan. Katakunci: DCL, komposisikia, kekerasan, struktur mikr

Mucocele geante de l’enfant

Les mucocèles sont des formations pseudo kystiques expansives des sinus de la face. Elles sont souvent diagnostiquées tardivement du fait de l’absence de signes spécifiques. Le bilan radiologique basé sur la TDM et ou l’IRM est essentiel pour confirmer le diagnostic et établir le bilan d’extension. Nous rapportons le cas d’un enfant âgé de 4 ans et 6mois traité d’une mucocèle géante éthmoïdo- maxillaire.Mots clés : mucocèle ; enfant ; TDM ; IRM ; chirurgieMucoceles are pseudo-cystic expansive formations of the sinuses. They are often diagnosed lately because of the lack of specific signs. CT and MRI are essential for the diagnosis and to evaluate the extension.We report a case of child with ethmoide-maxillary mucocèle treated in our department.Key words: mucocele; child; CT; MRI; surger

Improved control strategy of DFIG-based wind turbines using direct torque and direct power control techniques

This paper presents different control strategies for a variable-speed wind energy conversion system (WECS), based on a doubly fed induction generator. Direct Torque Control (DTC) with Space-Vector Modulation is used on the rotor side converter. This control method is known to reduce the fluctuations of the torque and flux at low speeds in contrast to the classical DTC, where the frequency of switching is uncontrollable. The reference for torque is obtained from the maximum power point tracking technique of the wind turbine. For the grid-side converter, a fuzzy direct power control is proposed for the control of the instantaneous active and reactive power. Simulation results of the WECS are presented to compare the performance of the proposed and classical control approaches.Peer reviewedFinal Accepted Versio

Contenido de prolina en Solanum lycopersicum pretratado con glicina betaina y sometido a estrés salino

Las plantas han desarrollado varios mecanismos protectores para contrarrestar el estrés salino, uno de ellos es la acumulación de solutos compatibles como prolina y glicina betaina. Sin embargo, algunos cultivos como el tomate no acumulan glicina betaina, ante esto surge la alternativa de la aplicación exógena de estos compuestos. En este trabajo, se propuso evaluar el contenido de prolina en relación al estado hídrico en plántulas de Solanum lycopersicum  var. Río Grande “tomate” pretratado con diferentes concentraciones de glicina betaina y cultivadas en diferentes niveles de salinidad.  Plántulas fueron tratadas con glicina betaina a concentraciones de 0, 1 y 10 mM, y luego sometidas a cloruro de sodio: 0, 100 y 200 mM agregada esta sal a la solución de riego. Después de 10 días de tratamiento se cuantificó prolina y contenido relativo de agua. El contenido de prolina aumentó con el grado de salinidad y la aplicación de Glicina betaina 1 mM produjo un aumento significativo en NaCl 100mM.Palabras clave: prolina, glicina betaina, estrés salino, Solanu

Molecular analysis of HBV genotypes and subgenotypes in the Central-East region of Tunisia

<p>Abstract</p> <p>Background</p> <p>In Tunisia, country of intermediate endemicity for Hepatitis B virus (HBV) infection, most molecular studies on the virus have been carried out in the North of the country and little is known about other regions. The aim of this study was to determine HBV genotype and subgenotypes in Central-East Tunisia. A total of 217 HBs antigen positive patients were enrolled and determination of genotype was investigated in 130 patients with detectable HBV DNA. HBV genotyping methods were: PCR-RFLP on the pre-S region, a PCR using type-specific primers in the S region (TSP-PCR) and partial sequencing in the pre-S region.</p> <p>Results</p> <p>Three genotypes (D, B and A) were detected by the PCR-RFLP method and two (D and A) with the TSP-PCR method, the concordance between the two methods was 93%. Sequencing and phylogenetic analysis of 32 strains, retrieved the same genotype (D and A) for samples with concordant results and genotype D for samples with discordant results. The sequences of discordant genotypes had a restriction site in the pre-S gene which led to erroneous result by the PCR-RFLP method. Thus, prevalence of genotype D and A was 96% and 4%, respectively. Phylogenetic analysis showed the predominance of two subgenotypes D1 (55%) and D7 (41%). Only one strain clustered with D3 subgenotype (3%).</p> <p>Conclusions</p> <p>Predominance of subgenotype D7 appears to occur in northern regions of Africa with transition to subgenotype D1 in the East of the continent. HBV genetic variability may lead to wrong results in rapid genotyping methods and sequence analysis is needed to clarify atypical results.</p