973 research outputs found

    Selective parent ion axialization for improved efficiency of collision-induced dissociation in laser desorption-ionization Fourier transform ion cyclotron resonance mass spectrometry

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    AbstractWe have systematically established the excitation frequency, amplitude, duration, and buffer gas pressure for optimal axialization efficiency and mass selectivity of quadrupolar excitation-collisional cooling for isolation of parent ions for collision-induced dissociation in Fourier transform ion cyclotron resonance mass spectrometry. For example, at high quadrupolar excitation amplitude, ion axialization efficiency and selectivity are optimal when the applied quadrupolar excitation frequency is lower than the unperturbed ion cyclotron frequency by up to several hundred hertz. Moreover, at high buffer gas pressure (10−6 Torr), quadrupolar excitation duration can be quite short because of efficient collisional cooling of the cyclotron motion produced by magnetron-to-cyclotron conversion. Efficiency, detected signal magnitude, and mass resolving power for collision-induced dissociation (CID) product ions are significantly enhanced by prior parent ion axilization. With this method, we use argon CID to show that C+94 (m/z 1128) formed by Nd:YAG laser desorption-ionization behaves as a closed-cage structure

    A characterization of periodicity in the voltage time series of a riometer

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    Author Posting. © American Geophysical Union, 2020. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research: Space Physics 125(7), (2020): e2019JA027160, doi:10.1029/2019JA027160.This paper reveals unprecedented periodicity in the voltage series of relative ionospheric opacity meters (riometers) of the Canadian Riometer Array (CRA). In quiet times, the riometer voltage series is accurately modeled by a stochastic process whose components include both a six term expansion in harmonic functions and some amplitude modulated modes of lower signal to noise ratio (SNR). In units of cycles per sidereal day (cpsd), the frequencies of the six harmonic functions lie within 0.01 cpsd of an integer. Earth's rotation induces a splitting of the low SNR components, resulting in the appearance of nine multiplets in standardized power spectrum estimates of the considered CRA voltage series. A second feature of these spectrum estimates is a 6 min periodic element appearing in both the CRA voltage series and the proton mass density series of the Advanced Composition Explorer (ACE). Spectral peak frequencies have been detected, which lie near established solar mode frequency estimates. In addition, some of these peak frequency estimates are coincident with peak frequency estimates of the standardized power spectra for the time series of proton mass density and interplanetary magnetic field strength (IMF) at ACE.“Marshall_Francois_Supporting_Information_JGR_2019.pdf” contains a summary of the supporting information. The 1 hr sampled F10.7 series was obtained from DRAO (National Research Council, 2017). The three MAG time series of IMF strength were acquired from The ACE Science Center (2007), while the SWEPAM time series of proton mass density was acquired from Space Weather Prediction Center, National Oceanic and Atmospheric Administration (2018). The relevant data sets for the analysis of this paper are included in Marshall (2019). This work was supported by the Natural Sciences and Engineering Research Council of Canada (NSERC), Canadian Statistical Sciences Institute (CANSSI), Bonneyville Power Authority, and Queen's University. David J. Thomson, the official holder of the grants and contracts, provided research and conference funding to advance this project. Special thanks to Ken F. Tapping (DRAO of NRCan) for his guidance in finding the data sets relevant to solar radio emissions. Glen Takahara, of the Department of Mathematics and Statistics at Queen's University, suggested exploring different data sets to confirm the modal origin of spectral peaks observed in the Ottawa riometer of the CRA. Alessandra A. Pacini of the Arecibo Observatory recommended checking to see if some of the modes could have been driven by the harmonics of Earth's rotation. Frank Vernon of the Institute of Geophysics and Planetary Physics at Scripps Institution of Oceanography confirmed how seismic data could be expected to reveal coincident spectral peaks at the detected frequencies in the riometer standardized spectra.2020-10-2

    Scotland Registry for Ankylosing Spondylitis (SIRAS) – Protocol

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    Funding SIRAS was funded by unrestricted grants from Pfizer and AbbVie. The project was reviewed by both companies, during the award process, for Scientific merit, to ensure that the design did not compromise patient safety, and to assess the global regulatory implications and any impact on regulatory strategy.Publisher PD

    ROSSI X-RAY TIMING EXPLORER AND BeppoSAX OBSERVATIONS OF THE TRANSIENT X-RAY PULSAR XTE J1859+083

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    We present observations of the 9.8 s X-ray pulsar XTE J1859+083 made with the All Sky Monitor (ASM) and Proportional Counter Array (PCA) on board the Rossi X-ray Timing Explorer, and the Wide Field Camera (WFC) on board BeppoSAX. The ASM data cover a 12 year time interval and show that an extended outburst occurred between approximately MJD 50,250 and 50,460 (1996 June 16 to 1997 January 12). The ASM data excluding this outburst interval suggest a possible modulation with a period of 60.65 ± 0.08 days. Eighteen sets of PCA observations were obtained over an approximately one month interval in 1999. The flux variability measured with the PCA appears consistent with the possible period found with the ASM. The PCA measurements of the pulse period showed it to decrease nonmonotonically and then to increase significantly. Doppler shifts due to orbital motion rather than accretion torques appear to be better able to explain the pulse period changes. Observations with the WFC during the extended outburst give a position that is consistent with a previously determined PCA error box, but which has a significantly smaller error. The transient nature of XTE J1859+083 and the length of its pulse period are consistent with it being a Be/neutron star binary. The possible 60.65 day orbital period would be of the expected length for a Be star system with a 9.8 s pulse period

    A Search for Exozodiacal Clouds with Kepler

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    Planets embedded within dust disks may drive the formation of large scale clumpy dust structures by trapping dust into resonant orbits. Detection and subsequent modeling of the dust structures would help constrain the mass and orbit of the planet and the disk architecture, give clues to the history of the planetary system, and provide a statistical estimate of disk asymmetry for future exoEarth-imaging missions. Here we present the first search for these resonant structures in the inner regions of planetary systems by analyzing the light curves of hot Jupiter planetary candidates identified by the Kepler mission. We detect only one candidate disk structure associated with KOI 838.01 at the 3-sigma confidence level, but subsequent radial velocity measurements reveal that KOI 838.01 is a grazing eclipsing binary and the candidate disk structure is a false positive. Using our null result, we place an upper limit on the frequency of dense exozodi structures created by hot Jupiters. We find that at the 90% confidence level, less than 21% of Kepler hot Jupiters create resonant dust clumps that lead and trail the planet by ~90 degrees with optical depths >~5*10^-6, which corresponds to the resonant structure expected for a lone hot Jupiter perturbing a dynamically cold dust disk 50 times as dense as the zodiacal cloud.Comment: 22 pages, 6 figures, Accepted for publication in Ap

    Body mass index relates weight to height differently in women and older adults

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    This study was partly supported by the University of Manchester’s Health eResearch Centre (HeRC) funded by the Medical Research Council (MRC) Grant MR/K006665/1 and partly funded by the ESRC Obesity eLab Grant (RES-149-25-1076).Background Body mass index (BMI) tends to be higher among shorter adults, especially women. The dependence of BMI–height correlation on age and calendar time may inform us about temporal determinants of BMI. Methods Series of cross-sectional surveys: Health Survey for England, 1992–2011. We study the Benn Index, which is the coefficient in a regression of log(weight) on log(height). This is adjusted for age, gender and calendar time, allowing for non-linear terms and interactions. Results By height quartile, mean BMI decreased with increasing height, more so in women than in men (P < 0.001). The decrease in mean BMI in the tallest compared with the shortest height quartile was 0.77 in men (95% CI 0.69, 0.86) and 1.98 in women (95% CI 1.89, 2.08). Regression analysis of log(weight) on log(height) revealed that the inverse association between BMI and height was more pronounced in older adults and stronger in women than in men, with little change over calendar time. Conclusions Unlike early childhood, where taller children tend to have higher BMI, adults, especially women and older people, show an inverse BMI–height association. BMI is a heterogeneous measure of weight-for-height; height may be an important and complex determinant of BMI trajectory over the life course.Publisher PDFPeer reviewe

    Inelastic collapse of a randomly forced particle

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    We consider a randomly forced particle moving in a finite region, which rebounds inelastically with coefficient of restitution r on collision with the boundaries. We show that there is a transition at a critical value of r, r_c\equiv e^{-\pi/\sqrt{3}}, above which the dynamics is ergodic but beneath which the particle undergoes inelastic collapse, coming to rest after an infinite number of collisions in a finite time. The value of r_c is argued to be independent of the size of the region or the presence of a viscous damping term in the equation of motion.Comment: 4 pages, REVTEX, 2 EPS figures, uses multicol.sty and epsf.st

    Is oxygen limitation in warming waters a valid mechanism to explain decreased body sizes in aquatic ectotherms?

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    The authors would like to acknowledge funding from Australian Research Council (grant No. DP170104240) and the Kone Foundation (to AA), Horizon 2020 European research projects ClimeFish (grant No. 677039) (to ARB) and Australian Academy of Science (to JRM)Peer reviewedPostprintPostprin
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