Smart job searching system based on information retrieval techniques and similarity of fuzzy parameterized sets

Job searching for the proper vacancy among several choices is one of the most important decision-making problems. The necessity of dealing with uncertainty in such real-world problems has been a long-term research challenge which has originated from different methodologies and theories. The main contribution of this work is to match the applicant curriculum vitae (CV) with the best available job opportunities based on certain criteria. The proposed job searching system (JSS) implements a series of approaches which can be broken down into segmentation, tokenization, part of speech, gazetteer, and fuzzy inference to extract and arrange the required data from the job announcements and CV. Moreover, this study designs a fuzzy parameterized structure to store such data as well as a measuring tool to calculate the degree of similarity between the job requirements and the applicant’s CV. In addition, this system analyses the computed similarity scores in order to get the optimal job opportunities for the job seeker in descending order. The performance evaluation of the proposed system shows high recall and precision percentages for the matching process. The results also confirm the viability of the JSS approach in handling the fuzziness that is associated with the problem of job searching

Smart detection of offensive words in social media using the soundex algorithm and permuterm index

Offensive posts in the social media that are inappropriate for a specific age, level of maturity, or impression are quite often destined more to unadult than adult participants. Nowadays, the growth in the number of the masked offensive words in the social media is one of the ethically challenging problems. Thus, there has been growing interest in development of methods that can automatically detect posts with such words. This study aimed at developing a method that can detect the masked offensive words in which partial alteration of the word may trick the conventional monitoring systems when being posted on social media. The proposed method progresses in a series of phases that can be broken down into a pre-processing phase, which includes filtering, tokenization, and stemming; offensive word extraction phase, which relies on using the soundex algorithm and permuterm index; and a post-processing phase that classifies the users’ posts in order to highlight the offensive content. Accordingly, the method detects the masked offensive words in the written text, thus forbidding certain types of offensive words from being published. Results of evaluation of performance of the proposed method indicate a 99% accuracy of detection of offensive words

Management of Extremity Venous Thrombosis in Neonates and Infants: An Experience From a Resource Challenged Setting

We aimed to evaluate the outcome of different treatment modalities for extremity venous thrombosis (VT) in neonates and infants, highlighting the current debate on their best tool of management. This retrospective study took place over a 9-year period from January 2009 to December 2017. All treated patients were referred to the vascular and pediatric surgery departments from the neonatal intensive care unit. All patients underwent a thorough history-taking as well as general clinical and local examination of the affected limb. Patients were divided into 2 groups: group I included those who underwent a conservative treated with the sole administration of unfractionated heparin (UFH), whereas group II included those who were treated with UFH plus warfarin. Sixty-three patients were included in this study. They were 36 males and 27 females. Their age ranged from 3 to 302 days. Forty-one (65%) patients had VT in the upper limb, whereas the remaining 22 (35%) had lower extremity VT. The success rate of the nonsurgical treatment was accomplished in 81% of patients. The remaining 19% underwent limb severing, due to established gangrene. The Kaplan-Meier survival method revealed a highly significant increase in both mean and median survival times in those groups treated with heparin and warfarin compared to heparin-only group (P < .001). Nonoperative treatment with anticoagulation or observation (ie, wait-and-see policy) alone may be an easily applicable, effective, and a safe modality for management of VT in neonates and infants, especially in developing countries with poor or highly challenged resource settings

Fundamentals of FGF19 & FGF21 Action In Vitro and In Vivo

Fibroblast growth factors 19 (FGF19) and 21 (FGF21) have emerged as key regulators of energy metabolism. Several studies have been conducted to understand the mechanism of FGF19 and FGF21 action, however, the data presented has often been inconsistent and at times contradictory. Here in a single study we compare the mechanisms mediating FGF19/FGF21 actions, and how similarities/differences in actions at the cellular level between these two factors translate to common/divergent physiological outputs. Firstly, we show that in cell culture FGF19/FGF21 are very similar, however, key differences are still observed differentiating the two. In vitro we found that both FGF's activate FGFRs in the context of βKlotho (KLB) expression. Furthermore, both factors alter ERK phosphorylation and glucose uptake with comparable potency. Combination treatment of cells with both factors did not have additive effects and treatment with a competitive inhibitor, the FGF21 delta N17 mutant, also blocked FGF19's effects, suggestive of a shared receptor activation mechanism. The key differences between FGF21/FGF19 were noted at the receptor interaction level, specifically the unique ability of FGF19 to bind/signal directly via FGFR4. To determine if differential effects on energy homeostasis and hepatic mitogenicity exist we treated DIO and ob/ob mice with FGF19/FGF21. We find comparable efficacy of the two proteins to correct body weight and serum glucose in both DIO and ob/ob mice. Nevertheless, FGF21 and FGF19 had distinctly different effects on proliferation in the liver. Interestingly, in vivo blockade of FGF21 signaling in mice using ΔN17 caused profound changes in glycemia indicative of the critical role KLB and FGF21 play in the regulation of glucose homeostasis. Overall, our data demonstrate that while subtle differences exist in vitro the metabolic effects in vivo of FGF19/FGF21 are indistinguishable, supporting a shared mechanism of action for these two hormones in the regulation of energy balance