153 research outputs found
An investigation into domestic energy consumption behaviour and public awareness of renewable energy in Qatar
Governments around the world are trying to find viable solutions for reducing carbon emissions and pollution, one of the primary sources of which is domestic household consumption. Although Qatar is rich in fossil fuel energy resources, there is a strategic drive towards sustainability to decrease energy consumption overall whilst increasing the nation's dependence on clean and renewable energy. One of the areas to enhance sustainability is through reducing and managing the energy demands and habits of domestic users. This research examines the current energy use in Qatar with a view to making recommendations in regard to challenging and improving consumer behaviour in respect to energy efficiency. A mixed methods approach was untaken consisting of both qualitative and quantitative data. Quantitative data was gathered from a wide spread survey of n=410 Qatari based consumers in regard to their energy consumption behaviour, investigating avenues for enabling sustainable behaviour change. The qualitative data was been collected by interviewing a panel of energy experts in Qatar. The purpose of this research study is to gain valuable insight into Qatari residents' energy consumption behaviour and perception of renewable energy and sustainability. The results will help to identify solutions to Qatar's high consumption of electricity per capita. This study has further implications amongst similar nations and states to address energy consumptions where there is a natural abundance of fossil fuel energy resources. This study has found that users' education and awareness of the environmental impact is dependent on efficient energy monitoring and usage. However, due to the presence of energy subsidies in Qatar, citizens are not inclined to modify their energy consumption behaviour through economic means. This suggests that a greater awareness of the effects of excessive energy use is required through sustainability education to motivate behaviour change. The results of this study were analysed using self-determination and hierarchal needs theories, indicating that education and public engagement and awareness are the best options for domestic energy conservation in Qatar
Engineering models for the design of long-lasting, sustainable, cost-efficient and climate-responsive pavements for Ashghal road projects in the State of Qatar
The planning, design, construction and management of modern transportation infrastructures is
based on the use of continuously updated methodologies that consider, among others, the
concept of sustainability. In such a context, for the specific case of road pavements, it is of crucial
importance to carry out quantitative analyses based on the use of optimized engineering models.
These models explicitly consider environment-pavement interactions, environmental impacts
generated by all the components involved in the supply chain, and financial flows associated to
pavement construction and maintenance. Such an approach is being adopted by the Public Works
Authority (Ashghal) of the State of Qatar, that is developing and implementing models tailored
for its infrastructure projects and local environmental conditions. This paper provides an
overview of some of the employed models and methodologies that are based on the physics of
pavement structures and on the assessment of environmental and economic indicators. It is
shown that such an approach leads to significant improvements to current practice and to the
enhanced use of recycled materials, while still guaranteeing required pavement performance
B-cell activating factor (BAFF), BAFF promoter and BAFF receptor allelic variants in hepatitis C virus related Cryoglobulinemic Vasculitis and Non-Hodgkin's Lymphoma
Cryoglobulinemic Vasculitis (CV) is an autoimmune/lymphoproliferative disorder associated with HCV infection that in 5%–10% of cases evolves into a B cell Non-Hodgkin's Lymphoma (NHL). B-cell activating factor (BAFF) is a key regulator in B-cell development and survival. Particular genetic variants are responsible for BAFF signaling impairment in autoimmune and neoplastic diseases. We evaluated BAFF and BAFF-receptor (BAFF-R) polymorphisms in order to determine if they predispose to HCV-related CV and NHL. The analysis was performed on 416 HCV-chronically infected patients: 136 HCV without signs/symptoms of lymphoproliferations/autoimmunity (HCV), 166 HCV with CV (HCV-CV) and 114 HCV with NHL (HCV-NHL). Rs9514828 SNP on BAFF promoter, rs61756766 on BAFF-R and rs12428930 on the BAFF gene were evaluated by Real-Time PCR. Concerning rs9514828, the frequency of C/T genotype was significantly higher in HCV-CV than in HCV. The difference in the distribution of the T/T mutant genotype in HCV-CV compared to HCV was significant as well as the distribution of C/T and T/T genotype in HCV-NHL versus HCV. T minor allele was more frequent in HCV-NHL and HCV-CV than in HCV. The distribution of C/T + T/T (for the dominant model of penetrance C/T + T/T vs. C/C) was significantly higher in HCV-CV and HCV-NHL than in HCV. Genotyping of rs61756766 on BAFF-R coding gene, revealed C/T heterozygosis at a frequency of 11% in HCV-NHL versus 3% in HCV. The T minor allele frequency was higher in HCV-NHL than in HCV. No differences emerged by genotyping rs12428930 SNP on BAFF coding gene. Our results reinforce the hypothesis that BAFF/BAFF-R genetic pattern has a role in the pathogenesis of HCV-related lymphoproliferations. BAFF/BAFF-R variants could identify a risk haplotype for HCV related CV and NHL and a BAFF/BAFF-R genetic profile assessment could potentially contribute to tailoring anti-BAFF therapy by identifying patients with BAFF alterations in which the treatment could be more beneficial
Epidemiology of respiratory infections among adults in Qatar (2012-2017).
Limited data is available about the etiology of influenza like illnesses (ILIs) in Qatar. This study aimed at providing preliminary estimates of influenza and other respiratory infections circulating among adults in Qatar. We retrospectively collected data of about 44,000 patients who visited Hamad General Hospital clinics, sentinel sites, and all primary healthcare centers in Qatar between 2012 and 2017. All samples were tested for influenza viruses, whereas about 38,000 samples were tested for influenza and a panel of respiratory viruses using Fast Track Diagnostics (FTD) RT-PCR kit. Among all ILIs cases, 20,278 (46.5%) tested positive for at least one respiratory pathogen. Influenza virus was predominating (22.6%), followed by human rhinoviruses (HRVs) (9.5%), and human coronaviruses (HCoVs) (5%). A detection rate of 2-3% was recorded for mycoplasma pneumonia, adenoviruses, human parainfluenza viruses (HPIVs), respiratory syncytial virus (RSV), and human metapneumovirus (HMPV). ILIs cases were reported throughout the year, however, influenza, RSV, and HMPV exhibited strong seasonal peaks in the winter, while HRVs circulated more during fall and spring. Elderly (>50 years) had the lowest rates of influenza A (13.9%) and B (4.2%), while presenting the highest rates of RSV (3.4%) and HMPV (3.3%). While males had higher rates of HRVs (11.9%), enteroviruses (1.1%) and MERS CoV (0.2%), females had higher proportions of influenza (26.3%), HPIVs (3.2%) and RSV (3.6%) infections. This report provides a comprehensive insight about the epidemiology of ILIs among adults in the Qatar, as a representative of Gulf States. These results would help in improvement and optimization of diagnostic procedures, as well as control and prevention of the respiratory infections.This study was supported by funds from Hamad Medical Corporation (grant # 16335/16) and Qatar University (grant # QUCG-BRC-2018/2019-1)
Cleaning of ceramic membranes for produced water filtration
The application of ceramic microfiltration membranes to the tertiary treatment of produced water from an Arabian Gulf oilfield has been studied using a dedicated pilot plant. Studies were based on a previously published protocol in which the retentate stream was recycled so as to successively increase the feed concentration throughout the experimental run. Chemical cleaning in place (CIP) was applied between each run and the flux and permeability recovery recorded for various cleaning protocols studied, the CIP being based on the combination of caustic soda (NaOH) and citric acid. Surface analysis of the membrane, and specifically its hydrophilicity, was also conducted.
Results indicated the main influencing factor on permeability recovery from the CIP to be the employment of backflushing during the CIP itself. A final flux of 700 L m−2 h−1 was sustained through the application of 6 wt% NaOH with 6 wt% citric acid combined with backflushing at approximately twice the rate of the filtration cycle flux. A consideration of the impact of this flux value on the viability of two commercially-available ceramic membrane technologies indicated the footprint incurred to be slightly lower than that of the upstream induced gas flotation technology and corroborated a previously published estimate. The flux was sustained despite surface analysis indicating a loss of the innate hydrophilicity of the ceramic membrane
Drivers of MERS-CoV Emergence in Qatar
MERS-CoV (Middle East respiratory syndrome corona virus) antibodies were detected
in camels since 1983, but the first human case was only detected in 2012. This study sought to
identify and quantify possible drivers for the MERS-CoV emergence and spillover to humans. A list
of potential human, animal and environmental drivers for disease emergence were identified from
literature. Trends in possible drivers were analyzed from national and international databases,
and through structured interviews with experts in Qatar. The discovery and exploitation of oil
and gas led to a 5-fold increase in Qatar GDP coupled with a 7-fold population growth in the
past 30 years. The lifestyle gradually transformed from Bedouin life to urban sedentary life,
along with a sharp increase in obesity and other comorbidities. Owing to substantial governmental
support, camel husbandry and competitions flourished, exacerbating the already rapidly occurring
desertification that forced banning of free grazing in 2005. Consequently, camels were housed in
compact barns alongside their workers. The transition in husbandry leading to high density camel
farming along with increased exposure to humans, combined with the increase of camel movement for
the racing and breeding industry, have led to a convergence of factors driving spillover of MERS-CoV
from camels to humans
The sample of choice for detecting Middle East respiratory syndrome coronavirus in asymptomatic dromedary camels using real-time reverse-transcription polymerase chain reaction
The newly identified Middle East respiratory syndrome coronavirus (MERS-CoV), which causes severe respiratory disease, particularly in people with comorbidities, requires further investigation. Studies in Qatar and elsewhere have provided evidence that dromedary camels are a reservoir for the virus, but the exact modes of transmission of MERS-CoV to humans remain unclear. In February 2014, an assessment was made of the suitability and sensitivity of different types of sample for the detection of MERS-CoV by real-time reverse-transcription polymerase chain reaction (RT-PCR) for three gene targets: UpE (upstream of the E gene), the N (nucleocapsid) gene and open reading frame (ORF) 1a. Fifty-three animals presented for slaughter were sampled. A high percentage of the sampled camels (79% [95% confidence interval 66.9-91.5%, standard error 0.0625]; 42 out of 53) were shown to be shedding MERS-CoV at the time of slaughter, yet all the animals were apparently healthy. Among the virus-positive animals, nasal swabs were most often positive (97.6%). Oral swabs were the second most frequently positive (35.7%), followed by rectal swabs (28.5%). In addition, the highest viral load, expressed as a cycle threshold (Ct) value of 11.27, was obtained from a nasal swab. These findings lead to the conclusion that nasal swabs are the candidate sample of choice for detecting MERS-CoV using RT-PCR technology in apparently healthy camels
Middle East respiratory syndrome coronavirus in dromedary camels: An outbreak investigation
Background: Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe lower respiratory tract infection in people. Previous studies suggested dromedary camels were a reservoir for this virus. We tested for the presence of MERS-CoV in dromedary camels from a farm in Qatar linked to two human cases of the infection in October, 2013. Methods: We took nose swabs, rectal swabs, and blood samples from all camels on the Qatari farm. We tested swabs with RT-PCR, with amplification targeting the E gene (upE), nucleocapsid (N) gene, and open reading frame (ORF) 1a. PCR positive samples were tested by different MERS-CoV specific PCRs and obtained sequences were used for phylogentic analysis together with sequences from the linked human cases and other human cases. We tested serum samples from the camels for IgG immunofluorescence assay, protein microarray, and virus neutralisation assay. Findings: We obtained samples from 14 camels on Oct 17, 2013. We detected MERS-CoV in nose swabs from three camels by three independent RT-PCRs and sequencing. The nucleotide sequence of an ORF1a fragment (940 nucleotides) and a 4·2 kb concatenated fragment were very similar to the MERS-CoV from two human cases on the same farm and a MERS-CoV isolate from Hafr-Al-Batin. Eight additional camel nose swabs were positive on one or more RT-PCRs, but could not be confirmed by sequencing. All camels had MERS-CoV spike-binding antibodies that correlated well with the presence of neutralising antibodies to MERS-CoV. Interpretation: Our study provides virological confirmation of MERS-CoV in camels and suggests a recent outbreak affecting both human beings and camels. We cannot conclude whether the people on the farm were infected by the camels or vice versa, or if a third source was responsible. Funding: European Union projects EMPERIE (contract number 223498), ANTIGONE (contract number 278976), and the VIRGO consortium
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