The Effects of Intermittent Solar Radiation in Off-grid Solar Power System A Case Study of Two Cities; Sacramento, CA and Miami, FL 'Worst Month' method

This study illustrates the impact of the solar radiation by comparing the design of two off-grid PV systems installed in two different locations have same annual average solar irradiation (insolation) values at fixed tilt angle. The case study selected the city of Sacramento, CA and Miami, FL. The monthly average Irradiation values in Sacramento are very diverse where the minimum, average and maximum values are spaced compared with the values in Miami which have no significant variation of solar irradiation from month to month. Comparing the Design of the two different systems will reflect the impact of the sporadic solar insolation on the rating values for the components of each system, which is affecting PV system cost. The design assumes the same load based and the worst case scenario of the solar irradiation. Each system will consist of PV modules, charge controller, power inverter and batteries

Incomplete Kawasaki Disease in a Three Month Old Infant

Kawasaki disease (KD) is an acute systemic vasculitis of unknown aetiology that has largely replaced rheumatic heart diseaseas a cause of acquired heart disease in children of many developed countries. We report a case of incomplete KD in a threemonth-old girl. The diagnosis of incomplete KD was made after exclusion of conditions with similar presentation. She wastreated with intravenous immunoglobulin following which she made an uneventful recovery but demonstrated thrombocytosisin the second week of convalescence. It is important for the treating physicians to become aware of the incomplete KD asprompt diagnosis and early treatment of these patients with intravenous immunoglobulin is vital for the prevention of lethalcoronary complications. Physicians need to have a "high index of suspicion" for KD and even, higher for IKD

Helium diffraction and acoustic phonons of graphene grown on copper foil.

We report helium diffraction from graphene grown by chemical vapour deposition (CVD) using copper foil. This method reveals acoustic phonons, which are physically important to thermal conductance as well as a sensitive probe of graphene's interactions with the underlying substrate. Helium diffraction is made possible by the high quality of graphene produced by a recently reported "peel-off method". The graphene lattice parameter was found to remain constant in the temperature range between 110 and 500 K. The measured parabolic dispersion of the flexural mode along (Gamma) over bar (M) over bar allows determining the bending rigidity k = ( 1.30 +/- 0.15) eV, and the graphene-Cu coupling strength g = ( 5.7 +/- 0.4) x 10(19) N/m(3). Unlike analytics employing atomic resolution microscopy, we obtain information on the atomic-scale quality of the graphene over mm length scales, suggesting the potential for Helium atom scattering to become an important tool for controlling the quality of industrially produced graphene

Performance of a Hybrid Wind-Grid-Load Energy System

A hybrid energy system consisting of a wind driven generator (WG) and a power utilities grid are interconnected. The hybrid energy system provides a constant power to an AC load regardless the surrounding weather conditions. The interconnection uses a controlled single phase full wave bridge rectifier. The bridge operates in the inverter mode of operation. This is done in purpose to guaranty the extraction of the real power from the wind driven generator. The extracted power is supplied to a constant AC load and any excess of power from the wind renewable energy source is injected into the power utility grid. At any pretended surrounding weather conditions, maximum extraction of power from the renewable energy source is targeted. This is done through the realization of a self-adjusted firing angle controller responsible of triggering the semiconductor elements of the controlled bridge rectifier. The performance of the proposed system has been simulated in MATLAB/SIMULINK environment and tested practically by building a laboratory prototype model. Quite satisfactory and encouraging results have been obtained

Home used, patient self-managed, brain-computer interface for the management of central neuropathic pain post spinal cord injury: usability study

Background: Central Neuropathic Pain (CNP) is a frequent chronic condition in people with spinal cord injury (SCI). Previously, we showed that using laboratory brain-computer interface (BCI) technology for neurofeedback (NFB) training, it was possible to reduce CNP in people with SCI. In this study, we show results of patient self-managed treatment in their homes with a BCI-NFB using a consumer EEG device. Methods Users: People with chronic SCI (17 M, 3 F, 50.6 ± 14.1 years old), and CNP ≥4 on a Visual Numerical Scale. Location: Laboratory training (up to 4 sessions) followed by home self-managed NFB. User Activity: Upregulating the EEG alpha band power by 10% above a threshold and at the same time downregulating the theta and upper beta (20-30 Hz) band power by 10% at electrode location C4. Technology: A consumer grade multichannel EEG headset (Epoch, Emotiv, USA), a tablet computer and custom made NFB software. Evaluation: EEG analysis, before and after NFB assessment, interviews and questionnaires. Results Effectiveness: Out of 20 initially assessed participants, 15 took part in the study. Participants used the system for 6.9 ± 5.5 (median 4) weeks. Twelve participants regulated their brainwaves in a frequency specific manner and were most successful upregulating the alpha band power. However they typically upregulated power around their individual alpha peak (7.6 ± 0.8 Hz) that was lower than in people without CNP. The reduction in pain experienced was statistically significant in 12 and clinically significant (greater than 30%) in 8 participants. Efficiency: The donning was between 5 and 15 min, and approximately 10–20% of EEG data recorded in the home environment was noise. Participants were mildly stressed when self-administering NFB at home (2.4 on a scale 1–10). User satisfaction: Nine participants who completed the final assessment reported a high level of satisfaction (QUESQ, 4.5 ± 0.8), naming effectiveness, ease of use and comfort as main priorities. The main factors influencing frequency of NFB training were: health related issues, free time and pain intensity. Conclusion: Portable NFB is a feasible solution for home-based self-managed treatment of CNP. Compared to pharmacological treatments, NFB has less side effects and provides users with active control over pain. Trial registration: GN15NE124, Registered 9th June 2016

Bioconjugates: A New Class of Therapeutics for Cancer Treatment

مثل المرافقات الحيوية فئة جديدة من العلاجات التي تبشر بالخير في علاج السرطان. تتشكل هذه المركبات من خلال الجمع بين جزيء استهداف ، مثل الجسم المضاد أو الببتيد ، مع عامل علاجي ، مثل عقار العلاج الكيميائي أو السم. يسمح هذا النهج بالتسليم المستهدف للعامل العلاجي للخلايا السرطانية ، وتقليل الأضرار التي تلحق بالأنسجة السليمة وتقليل الآثار الجانبية. أظهرت المقارنات الحيوية إمكانات كبيرة في الدراسات قبل السريرية والسريرية ، مع العديد من الأدوية المعتمدة من إدارة الغذاء والدواء والمتاحة حاليًا لعلاج السرطان. هناك عدة أنواع من المركبات الحيوية التي يتم تطويرها حاليًا لعلاج السرطان ، بما في ذلك اتحادات الأدوية والأجسام المضادة ADCs، وتقارنات العقاقير الببتيدية PDCs، واتحادات الجسيمات النانوية (NDCs). ADCs هي أكثر أنواع المركبات الحيوية ترسخًا وقد تمت الموافقة عليها لعلاج عدة أنواع من السرطان ، بما في ذلك سرطان الثدي وسرطان الغدد الليمفاوية وسرطان الدم. PDCs و NDCs هي فئات جديدة من المركبات الحيوية التي لا تزال في مراحل التطور السريرية قبل السريرية والمبكرة. تهدف الأبحاث الجارية في هذا المجال إلى تحسين فعالية وسلامة المركبات الحيوية وتوسيع استخدامها لتشمل مجموعة واسعة من أنواع السرطان. مع استمرار تقدم البحث في هذا المجال ، يمكننا أن نتوقع رؤية المزيد من العقاقير الموصلة بيولوجيًا المبتكرة والفعالة التي يتم تطويرها في المستقبل. تم تصميم هذه الأدوية لاستهداف خلايا سرطانية معينة ، مع ترك الخلايا السليمة دون أن تصاب بأذى ، ولديها القدرة على إحداث ثورة في علاج السرطان. علاوة على ذلك ، يمكن تصميم المقارنات الحيوية لتناسب المرضى الفرديين ، مما يسمح بعلاج السرطان المخصص والموجه. مثل المرافقات الحيوية فئة جديدة من العلاجات التي تبشر بالخير في علاج السرطان. تتشكل هذه المركبات من خلال الجمع بين جزيء استهداف ، مثل الجسم المضاد أو الببتيد ، مع عامل علاجي ، مثل عقار العلاج الكيميائي أو السم. يسمح هذا النهج بالتسليم المستهدف للعامل العلاجي للخلايا السرطانية ، وتقليل الأضرار التي تلحق بالأنسجة السليمة وتقليل الآثار الجانبية. أظهرت المقارنات الحيوية إمكانات كبيرة في الدراسات قبل السريرية والسريرية ، مع العديد من الأدوية المعتمدة من إدارة الغذاء والدواء والمتاحة حاليًا لعلاج السرطان. هناك عدة أنواع من المركبات الحيوية التي يتم تطويرها حاليًا لعلاج السرطان ، بما في ذلك اتحادات الأدوية والأجسام المضادة ADCs، وتقارنات العقاقير الببتيدية PDCs، واتحادات الجسيمات النانوية (NDCs). ADCs هي أكثر أنواع المركبات الحيوية ترسخًا وقد تمت الموافقة عليها لعلاج عدة أنواع من السرطان ، بما في ذلك سرطان الثدي وسرطان الغدد الليمفاوية وسرطان الدم. PDCs و NDCs هي فئات جديدة من المركبات الحيوية التي لا تزال في مراحل التطور السريرية قبل السريرية والمبكرة. تهدف الأبحاث الجارية في هذا المجال إلى تحسين فعالية وسلامة المركبات الحيوية وتوسيع استخدامها لتشمل مجموعة واسعة من أنواع السرطان. مع استمرار تقدم البحث في هذا المجال ، يمكننا أن نتوقع رؤية المزيد من العقاقير الموصلة بيولوجيًا المبتكرة والفعالة التي يتم تطويرها في المستقبل. تم تصميم هذه الأدوية لاستهداف خلايا سرطانية معينة ، مع ترك الخلايا السليمة دون أن تصاب بأذى ، ولديها القدرة على إحداث ثورة في علاج السرطان. علاوة على ذلك ، يمكن تصميم المقارنات الحيوية لتناسب المرضى الفرديين ، مما يسمح بعلاج السرطان المخصص والموجه.Bioconjugates represent a novel class of therapeutics that offer promise in the treatment of cancer. These compounds are formed by combining a targeting molecule, such as an antibody or peptide, with a therapeutic agent, such as a chemotherapy drug or toxin. This approach allows for targeted delivery of the therapeutic agent to cancer cells, minimizing damage to healthy tissues and reducing side effects. Bioconjugates have shown significant potential in preclinical and clinical studies, with several FDA-approved drugs currently available for the treatment of cancer. There are several types of bioconjugates currently being developed for cancer treatment, including antibody-drug conjugates (ADCs), peptide-drug conjugates (PDCs), and nanoparticle-drug conjugates (NDCs). ADCs are the most well-established type of bioconjugate and have been approved for the treatment of several types of cancer, including breast cancer, lymphoma, and leukemia. PDCs and NDCs are newer classes of bioconjugates that are still in the preclinical and early clinical stages of development. Ongoing research in this field aims to improve the efficacy and safety of bioconjugates and expand their use to a wider range of cancer types. As research in this field continues to advance, we can expect to see even more innovative and effective bioconjugate drugs being developed in the future. These drugs are designed to target specific cancer cells, while leaving healthy cells unharmed, and have the potential to revolutionize cancer treatment. Furthermore, bioconjugates can be tailored to individual patients, allowing for personalized and targeted cancer therapy. &nbsp

Detection of Herpes Viruses in Aggressive Periodontitis Patients in Mosul

The aim of the study is to estimate the frequency of herpes viruses HCMV, EBV1 and HSV in periodontal pocket samples of aggressive periodontitis patients. This study was carried out on total number of 24 Aggressive Periodontitis patients, 14 (58%) males and 10 (42%) females, aging between 20-?40 years old). Periodontal pocket samples were collected from three deepest pocket sites and nested PCR technique was used to detect HCMV, EBV and HS

Serum and Salivary Markers in Aggressive Periodontitis Patients In Mosul

This study also showed direct correlation between serum IL-1? and Salivary peroxidase, also between (IgA, total protein and peroxidase Specific activity in saliva). Finally presence of direct correlation between peroxidase specific activity and total protein. The aims of the study is to assess and compare serum levels of cytokines (IL-8,IL-6,IL-1?,IFN-? and TNF-?) and salivary markers (sIgA, peroxidase, peroxidase specific activity and total protein) in aggressive periodontitis patients and periodontally healthy individuals in Mosul. This study was carried out on a total number of 49 subjects, 24 Aggressive Periodontitis patients,14 males and 10 females, aging between 20 - ?40 years, and 25 healthy subjects as control group which consisted of 14 males and 11 females aging between 20-45 years. All patients were systemically healthy. Five ml of venous blood and saliva were withdrawn from each patient and control subject, for assessments of serum cytokines (IL-8,IL-6,IL-1?,IFN-? and TNF-? ) and salivary markers (sIgA, total protein and peroxidase specific activity) usin

Effect of some organic fillers on the mechanical properties of high density polyethylene

In this paper , the mechanical properties of high density polyethylene (HDPE grade M624) produced by SCPI / Basra

Effect of some organic fillers on the mechanical properties of high density polyethylene

In this paper , the mechanical properties of high density polyethylene (HDPE grade M624) produced by SCPI / Basrah – Iraq , mixed with the wood flour and bagasse as fillers with 10-50 % w/w have been studied . The maximum tensile strength was observed at 10% w/w of fillers ratio . The elongation , impact strength and fracture energy were decreased with increasing of fillers ratio while the Young modulus and hardness were increased