Diabetes mellitus: The epidemic of the century

The epidemic nature of diabetes mellitus in different regions is reviewed. The Middle East and North Africa region has the highest prevalence of diabetes in adults (10.9%) whereas, the Western Pacific region has the highest number of adults diagnosed with diabetes and has countries with the highest prevalence of diabetes (37.5%). Different classes of diabetes mellitus, type 1, type 2, gestational diabetes and other types of diabetes mellitus are compared in terms of diagnostic criteria, etiology and genetics. The molecular genetics of diabetes received extensive attention in recent years by many prominent investigators and research groups in the biomedical field. A large array of mutations and single nucleotide polymorphisms in genes that play a role in the various steps and pathways involved in glucose metabolism and the development, control and function of pancreatic cells at various levels are reviewed. The major advances in the molecular understanding of diabetes in relation to the different types of diabetes in comparison to the previous understanding in this field are briefly reviewed here. Despite the accumulation of extensive data at the molecular and cellular levels, the mechanism of diabetes development and complications are still not fully understood. Definitely, more extensive research is needed in this field that will eventually reflect on the ultimate objective to improve diagnoses, therapy and minimize the chance of chronic complications development

Diabetes mellitus: The epidemic of the century

The epidemic nature of diabetes mellitus in different regions is reviewed. The Middle East and North Africa region has the highest prevalence of diabetes in adults (10.9%) whereas, the Western Pacific region has the highest number of adults diagnosed with diabetes and has countries with the highest prevalence of diabetes (37.5%). Different classes of diabetes mellitus, type 1, type 2, gestational diabetes and other types of diabetes mellitus are compared in terms of diagnostic criteria, etiology and genetics. The molecular genetics of diabetes received extensive attention in recent years by many prominent investigators and research groups in the biomedical field. A large array of mutations and single nucleotide polymorphisms in genes that play a role in the various steps and pathways involved in glucose metabolism and the development, control and function of pancreatic cells at various levels are reviewed. The major advances in the molecular understanding of diabetes in relation to the different types of diabetes in comparison to the previous understanding in this field are briefly reviewed here. Despite the accumulation of extensive data at the molecular and cellular levels, the mechanism of diabetes development and complications are still not fully understood. Definitely, more extensive research is needed in this field that will eventually reflect on the ultimate objective to improve diagnoses, therapy and minimize the chance of chronic complications development

Technical Analysis of Organic Rankine Cycle System Using Low-Temperature Source to Generate Electricity in Ship

Nowadays, the shipping sector has growth rapidly as followed by the increasing of world population and the demands for public transportation via sea. This issue entails the large attention on emission, energy efficiency and fuel consumption on the ship. Waste Heat Recovery (WHR) is one of the solution to overcome the mentioned issue and one of the WHR method is by installing Organic Rankine Cycle (ORC) system in ship. ORC demonstrate to recover and exploit the low temperature waste heat rejected by the ship power generation plant. The main source of heat to be utilized is obtained from container ship (7900 kW BHP, DWT 10969 mt) ship jacket water cooling system and use R-134a as a refrigerant. The main equipment consists of evaporator, condenser, pump and steam turbine to generate the electricity. The main objective is to quantifying the estimation of electrical power which can be generated at typical loads of the main engine. As the final result of analysis, the ORC system is able to generate the electricity power ranged from 77,5% - 100% of main engine load producing power averagely 57,69 kW

High sensitivity and multifunctional micro-Hall sensors fabricated using InAlSb/InAsSb/InAlSb heterostructures

Further diversification of Hall sensor technology requires development of materials with high electron mobility and an ultrathin conducting layer very close to the material's surface. Here, we describe the magnetoresistive properties of micro-Hall devices fabricated using InAlSb/InAsSb/InAlSb heterostructures where electrical conduction was confined to a 30 nm-InAsSb two-dimensional electron gas layer. The 300 K electron mobility and sheet carrier concentration were 36 500 cm(2) V-1 s(-1) and 2.5 x 10(11) cm(-2), respectively. The maximum current-related sensitivity was 2 750 V A(-1) T-1, which was about an order of magnitude greater than AlGaAs/InGaAs pseudomorphic heterostructures devices. Photolithography was used to fabricate 1 mu m x 1 mu m Hall probes, which were installed into a scanning Hall probe microscope and used to image the surface of a hard disk

Shear Behavior of Reinforced Concrete Inverted-T Deep Beam

Contrary to top-loaded deep beams, Inverted-T (IT) deep beams are loaded on ledges at the beam’s bottom chord. The presence of the load near the bottom of the beams creates a tension field in the web at the loading points. An experimental investigation was carried out in which 8 specimens of reinforced concrete IT deep beams were tested and the effect of the following variables was studied: changing the hanger diameter, hanger arrangement in terms of spacing and distribution distance, hanger reinforcement ratio, vertical and horizontal web shear reinforcement diameter, and spacing. In addition, all the tested beams had long ledges extending to the end of the beam. It was concluded that hanger reinforcement diameter and horizontal web shear reinforcement have an insignificant effect on the IT deep beam capacity. While the change in hanger arrangement, vertical web reinforcement, and ledge length has a significant effect on IT deep beam capacity. The maximum spacing of the hanger reinforcement and the minimum hanger reinforcement ratio passing through the load plate length will be studied in the following publication. A finite element model (FEM) was presented to predict the behavior of IT deep beams. The simulation was carried out using the ABAQUS 2017 software program. The results of the numerical model showed good agreement with the experimental program. Analysis using design codes was checked against the experimental data, where the computed beam capacities were compared to those obtained from the test results. The comparison showed a remarkable difference between the predictions using the design codes and the test results. Computation using design codes significantly underestimated the capacities of the beams. Doi: 10.28991/CEJ-2023-09-05-04 Full Text: PD

Bandwidth Enhancement in Microstrip Patch Antenna Using Rhombus Shape Slot

The Microstrip antennas are the low profile radiators. It is so because of their numerous features such as low volume, compactness, low fabrication cost and mechanical robustness. Numerous techniques have been suggested to improve the Microstrip patch antenna characteristics. In this paper we discuss the slot coupled patch antenna, one with a rectangular patch and other one with a rhombus shaped patch. And study the antenna characteristics of both the antenna such as bandwidth, radiation loss and gain. The results indicate the impact of changing patch on the antenna performance. To excite the structure the microstrip line is placed below the slot. The slot is made between the feed line and the radiating patch substrate. Fields from the microstrip line will be coupled to the patch through this narrow slot. ANSYS HFSS is used to carry out the procedure DOI: 10.17762/ijritcc2321-8169.150313

Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease: Valuable Programming Insights from Anecdotal Observations

In this article, we use a case to illustrate and discuss some practically important learning points about programming subthalamic nucleus deep brain stimulation for Parkinson’s disease patients and highlight clinically relevant issues resulting from anatomical and device-related anomalies. These include the phenomenon of a dominant subthalamic nucleus, clinical variability with delayed response to stimulation, equivalence of electrical charge when using short-pulse settings, and issues regarding conversion of settings between constant-current and constant-voltage devices that are increasingly common with the use of device components from multiple manufacturers

Security in smartphones and tablets

Mobile devices like smartphones and tablets are turning into a vehicle for productive and advantageous approach to access, find and share information/data. However, lack of the efficient and proper security measures has paved a way for the cyber-attackers to get this information and misuse it for their own purpose. Data leakage resulting from device loss or theft is major security risk associated with the smartphones and other mobile devices. One way to protect the data is to use encryption/decryption technique. Though there is many encryption/decryption technique available but most of them are susceptible to various attacks. Another problem is there is no proper encryption/decryption procedure for end point to end point security (between two or more phones). We proposed novel key generation techniques to be used in encryption/decryption process. The same technique can also be used for end point to end point secure communication. These techniques have been tested against various attacks on real android devices and it has been found that it withstand all types of attacks