147 research outputs found

    The Impact of Control Fraud on the Banking System: Evidence from a developing Country

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    Recent global financial crisis have awakened the need to regulate corporate governance across the world. The fall of multi-national companies like Enron in the USA and Bank of Credit and Commerce International (BCCI) in the United Kingdom have brought to the fore the impact of fraud in corporate governance regulation. In Nigeria, fraud in the banking sector has reached epidemic levels contributing to the Nation’s economic depression. This research tests the hypothesis that the inadequacy of corporate governance regulation in the banking sector creates the opportunity for a web of financial crimes where the company is used as a fraud mechanism. This type of fraud, known as control fraud mainly involves people who are in ‘control’ of the company, particularly directors using their position as a weapon to defraud. The evidence collected from 5 banks involved in the recent banking crisis in Nigeria in 2008 and 2009 financial years supported this hypothesis. The research adopts a socio-legal methodology to assess the link between corporate governance regulation and control fraud. The research further suggests that control fraud is a peculiar challenge of Nigerian banks and there is therefore the need for regulatory involvement that takes into consideration the peculiarities of the country and addresses the institutional challenges faced in the system, particularly corruption and regulatory enforcement It is important that corporate governance regulation is specifically designed to meet the needs of a particular jurisdiction as opposed to transplanting western norms

    Anatomic Site Variability in Rat Skeletal Uptake and Desorption Of Fluorescently Labeled Bisphosphonate

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    Objectives Bisphosphonates commonly used to treat osteoporosis, Paget’s disease, multiple myeloma, hypercalcemia of malignancy and osteolytic lesions of cancer metastasis have been associated with bisphosphonate-associated jaw osteonecrosis (BJON). The underlying pathogenesis of BJON is unclear, but disproportionate bisphosphonate concentration in the jaw has been proposed as one potential etiological factor. This study tested the hypothesis that skeletal biodistribution of intravenous bisphosphonate is anatomic site-dependent in a rat model system. Materials and Methods Fluorescently labeled pamidronate was injected intravenously in athymic rats of equal weights followed by in vivo whole body fluorimetry, ex vivo optical imaging of oral, axial and appendicular bones and ethylenediaminetetraacetic acid bone decalcification to assess hydroxyapatite-bound bisphosphonate. Results Bisphosphonate uptake and bisphosphonate released per unit calcium were similar in oral and appendicular bones but lower than those in axial bones. Hydroxyapatite-bound bisphosphonate liberated by sequential acid decalcification was highest in oral relative to axial and appendicular bones (p \u3c 0.05). Conclusions This study demonstrates regional differences in uptake and release of bisphosphonate from oral, axial and appendicular bones of immune deficient rats

    Towards Conserving Nigeria’s Environment through Environmental Management Education

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    Environmental conservation involves the wise use of resources and their preservation from reckless exploitation and wanton destruction. In contemporary Nigeria however, the ideals of conservation have failed to be properly integrated into the National development agenda. Widespread ignorance and low levels environmental awareness have been identified as prominent factors responsible for this despicable state of affairs. Since education remains the cure for ignorance, this paper therefore, aims at emphasizing the urgent imperative for the incorporation of environmental management education as a major component of an integrative framework for the conservation of Nigeria’s environment. The paper contends that effective environmental conservation may never be attained unless and until requisite skills are developed and sufficient awareness created nationally and locally through a robust programme of environmental management education. The paper recommends the adoption of environmental management education as an important component of our effort to ensure effective conservation and national development. Specifically, environmental management education should be introduced as a subject in the primary and secondary schools, while universities and other tertiary institutions should offer it as a general course and make efforts to establish Environmental Management Department in the Faculty of Environmental Studies as approved by the National Universities Commission. Key words: Environmental Management, Education, Conservation, Resources, Awareness

    Timing of therapy for latent tuberculosis infection among immigrants presenting to a U.S. public health clinic: a retrospective study

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    <p>Abstract</p> <p>Background</p> <p>In the U.S. more than half of incident tuberculosis (TB) cases occur in immigrants. Current guidelines recommend screening and treatment for latent TB infection (LTBI) within 5 years of arrival to the U.S. This study evaluates the timing of LTBI therapy among immigrants presenting for care to a public health TB clinic.</p> <p>Methods</p> <p>Retrospective chart review of patients prescribed LTBI treatment based on medical records from Prince Georges County Health Department.</p> <p>Results</p> <p>1882 immigrants received LTBI therapy at Prince Georges County Health Department between 1999 and 2004. 417 of these patients were diagnosed with LTBI through contact investigations and were excluded from the analysis. Among the remaining 1465 individuals, median time from arrival to the U.S. until initiation of LTBI therapy was 5 months (range 0–42.4 years). 16% of all immigrants initiated therapy more than 5 years after arrival to the U.S. A logistic regression model using risks identified on univariate analysis revealed that referral for therapy by non-immigration proceedings was the strongest predictor of initiation of therapy more than 5 years after arrival to the U.S. Other factors associated with > 5 year U.S. residence prior to initiation of LTBI therapy included female gender (adjusted odds ratio (AOR) 1.8, 95% CI 1.2–2.6), age ≥ 35 (AOR = 4.1, 95% 2.5–6.6), and originating from Latin American and the Caribbean (AOR = 1.9, 95% CI 1.3–3.0).</p> <p>Conclusion</p> <p>Foreign-born individuals who are not referred for LTBI therapy through immigration proceedings are less likely to receive LTBI therapy within 5 years of arrival to the U.S. These data highlight the need to explore other mechanisms for timely LTBI screening beyond services provided by immigration.</p

    McCune-Albright syndrome

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    McCune-Albright syndrome (MAS) is classically defined by the clinical triad of fibrous dysplasia of bone (FD), café-au-lait skin spots, and precocious puberty (PP). It is a rare disease with estimated prevalence between 1/100,000 and 1/1,000,000. FD can involve a single or multiple skeletal sites and presents with a limp and/or pain, and, occasionally, a pathologic fracture. Scoliosis is common and may be progressive. In addition to PP (vaginal bleeding or spotting and development of breast tissue in girls, testicular and penile enlargement and precocious sexual behavior in boys), other hyperfunctioning endocrinopathies may be involved including hyperthyroidism, growth hormone excess, Cushing syndrome, and renal phosphate wasting. Café-au-lait spots usually appear in the neonatal period, but it is most often PP or FD that brings the child to medical attention. Renal involvement is seen in approximately 50% of the patients with MAS. The disease results from somatic mutations of the GNAS gene, specifically mutations in the cAMP regulating protein, Gs alpha. The extent of the disease is determined by the proliferation, migration and survival of the cell in which the mutation spontaneously occurs during embryonic development. Diagnosis of MAS is usually established on clinical grounds. Plain radiographs are often sufficient to make the diagnosis of FD and biopsy of FD lesions can confirm the diagnosis. The evaluation of patients with MAS should be guided by knowledge of the spectrum of tissues that may be involved, with specific testing for each. Genetic testing is possible, but is not routinely available. Genetic counseling, however, should be offered. Differential diagnoses include neurofibromatosis, osteofibrous dysplasia, non-ossifying fibromas, idiopathic central precocious puberty, and ovarian neoplasm. Treatment is dictated by the tissues affected, and the extent to which they are affected. Generally, some form of surgical intervention is recommended. Bisphosphonates are frequently used in the treatment of FD. Strengthening exercises are recommended to help maintaining the musculature around the FD bone and minimize the risk for fracture. Treatment of all endocrinopathies is required. Malignancies associated with MAS are distinctly rare occurrences. Malignant transformation of FD lesions occurs in probably less than 1% of the cases of MAS

    Attitudes and perceptions regarding entrepreneurship around the world : a cluster analysis approach

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    Nowadays it is believed that entrepreneurship could be a driving force in growth and development. For the achievement of a relevant national entrepreneurship rate the social and economic business environment can be crucial. However, despite the international attention given to entrepreneurship, it is not known if it is a global phenomenon or if there are particular regions where the entrepreneurial activity is specially recognized by society. Applying cluster analysis statistical techniques to a dataset gathered by the Global Entrepreneurship Monitor (GEM) and that includes, in 2010, 59 countries this paper intends to identify groups of countries with the same population attitude and perception regarding entrepreneurship

    Attitudes and perceptions regarding entrepreneurship around the world : a cluster analysis approach

    Get PDF
    Nowadays it is believed that entrepreneurship could be a driving force in growth and develop-ment. For the achievement of a relevant national entrepreneurship rate the social and economic business environment can be crucial. However, despite the international attention given to entrepreneurship, it is not known if it is a global phenomenon or if there are particular regions where the entrepreneurial activity is specially recognized by society. Applying cluster analysis statistical techniques to a dataset gathered by the Global Entrepreneurship Monitor (GEM) and that includes, in 2010, 59 countries this paper intends to identify groups of countries with the same population attitude and perception regarding entrepreneurship

    Culture in sustainable infrastructure: the polycentric cultural framework model

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    The state of infrastructure and services is widely perceived as a measure of development and a major catalyst for growth in both developed and developing economies. However, financing, maintaining and replicating existing infrastructures in areas of need have been mostly ineffective. In view of the widespread failures and poor state of infrastructure and services, there is a need to review current delivery and procurement frameworks. Given that sustainable infrastructure is also an essential prerequisite for sustainable development, this paper presents a polycentric cultural framework for infrastructure and service delivery; a framework which emphasises the integration of infrastructure users, communities, public and private sectors throughout the process of conceptualisation to actual delivery of infrastructure, by taking the recipients’ culture, beliefs and values into account. The framework also emphasises the use of systemic referendum among stakeholders by way of the traditional consultative processes and the collaborative consensus paradigm to achieve an effective and sustainable delivery of infrastructure and services
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