31 research outputs found

    Primary bone tumours in a tertiary hospital in Nigeria: 25 year review

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    In Vitro Antimicrobial Activity Of Crude Extracts From Plants Bryophyllum pinnatum And Kalanchoe crenata

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    Extracts from the leaves of Bryophyllum pinnatum and Kalanchoe crenata were screened for their antimicrobial activities. Solvents used included water, methanol, and local solvents such as palmwine, local gin (Seaman's Schnapps 40% alcoholic drink,) and “omi ekan-ogi” (Sour water from 3 days fermented milled maize). Leaves were dried and powdered before being soaked in solvents for 3 days. Another traditional method of extraction by squeezing raw juice from the leaves was also employed. All extracts were lyophilized. These extracts were tested against some Gram-negative organisms (Escherichia coli ATCC 25922, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Shigella flexneri, Salmonella paratyphi, Citrobacter spp); Gram-positive organisms Staphylococcus aureus ATCC 25213, Staphylococcus aureus, Enterococcus faecalis, Bacillus subtilis) and a fungus (Candida albicans). Agar well diffusion and broth dilution methods were used to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) at concentrations of 512mg/ml to 4mg/ml. All the organisms except Candida albicans were susceptible to the extracts obtained from the traditional method. The squeezed-leaf juice of Kalanchoe crenata was the most active one with MIC of 8 mg/ml against Pseudomonas aeruginosa, Klebsiella pneumoniae and Bacillus subtilis, 32 mg/ml against Shigella flexneri, 64 mg/ml against Escherichia coli and 128 mg/ml against the control strain Staphylococcus aureus while its MBC is 256 mg/ml against these organisms except Bacillus subtilis and Klebsiella pneumoniae. The Gram-positive organisms were more sensitive to the methanol and local gin-extract of Bryophyllum pinnatum. Extracts from other solvents showed moderate to weak activity. Keywords:Antimicrobial, Bryophyllum pinnatum, Kalanchoe crenata, Local solvents, Gram-positive organism, Gram-negative organism African Journal of Traditional and Complementary Medicine Vol. 4 (3) 2007: pp. 338-34

    Qualitative determination of chemical and nutritional composition of Parkia biglobosa (Jacq.) Benth

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    Qualitative determination of chemical and nutritional composition of Parkia biglobosa seeds an underexploited crop seed in Nigeria was carried out. Seeds of P. biglobosa were found to be rich in lipid, protein, carbohydrate, soluble sugars and ascorbic acid. The cotyledon was very nutritious, has less fibre and ash contents when compared to that of testa. The oil content was suitable for consumption since it contains very low acid and iodine contents. The oil has very high saponification value and hence would be useful in soap industry. Some simple reducing sugars, including lactose, were identified. Key words: Parkia bioglobosa, Qalitative determination, Industrial use, Saponification, underexploited.African Journal of Biotechnology Vol. 4 (8), pp. 812-81

    Mentorship in orthopaedic and trauma residency training programme in Nigeria: the residents' perspective

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    Background: Mentorship is important in residency training as it is necessary for personal and professional development of the resident traineesObjectives: This study documents mentorship in orthopaedic residency training programme in Nigeria by assessing the awareness of orthopaedic residents on the role of a mentor, willingness to be mentored and their perceived reasons for the possible lack of mentors/ participation of senior colleagues in a mentorship programmeMethod: This was a descriptive cross sectional study of 37 orthopaedic residents attending a revision course of the Faculty of Orthopaedics, National Postgraduate Medical College of Nigeria. Self-administered structured questionnaires were used to collect data. Data obtained was analyzed using SPSS version 21.0.Results: The mean age of the respondent was 34.7 ± 4.7 years. The Male: Female ratio was 19:1. The average number of years already spent in the residency programme by the respondents was 2.8 ± 0.9 years. Only 27% of residents had participated in a mentorship programme since they began residency programme but only half were still being mentored at the time of the study. Sixty-five percent reported no formal mentorship programme in their institutions. However, 73% of the respondents would want a formal mentorship programme in their institution. Ninety percent of the respondents desired to be mentored.Conclusion: Most residents are willing to be mentored. Consultants and trainers should ensure that the trainees are mentored.Keywords: Mentorship, Orthopaedic Residents, Residency Training, Fellowship Training Nigeri

    Traffic Management Problems in Lagos: A Focus on Alaba International Market Road, Ojo, Lagos State Nigeria

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    This study examines the traffic management problems resulting from traffic congestion in the study area. It also evaluates the opinion of the stakeholders in the transport sector such as the commuters, transport operators and private car owners on the traffic situations and management problems in the study area. The study depended upon the survey research technique to gather relevant data on the respondents, using the questionnaire as the research instrument. The research identified inter alia the traffic congestion causative factors as; over dependency on small occupancy vehicles, narrow road, indiscriminate parking, loading and off-loading of goods and passengers on the road, on-street trading, inability of the  traffic management agencies to evacuate crashed or breakdown vehicles on time and ineffective traffic control measure. The study recommends the expansion of the narrow road capacity to double lanes, provision of adequate parking facilities, increasing the number of the few bus terminal along the road, provision of adequate park and ride space, prohibition of on-street parking, effective traffic management techniques, pedestrians priority scheme, provision of mass transit buses, provision of more road furniture like traffic light, lane marking, frequent road assessment and maintenance in the study area. Keywords: transport, congestion, furniture, traffic, terminal, vehicles, technique, pedestrians

    MEDICINAL PLANTS USEFUL FOR MALARIA THERAPY IN OKEIGBO

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    There is increasing resistance of malaria parasites to chloroquine, the cheapest and commonly used drug for malaria in Nigeria. Artemisin, a product from medicinal plant indigenous to China, based on active principle of Artemisia annua, has been introduced into the Nigerian market. However not much has been done to project antimalaria properties of indigenous medicinal plants. This study thus, has the main objective of presenting medicinal plants used for malaria therapy in Okeigbo, Ondo State, South west Nigeria. Focus group discussions and interview were held about plants often found useful for malaria therapy in the community. Fifty species (local names) including for example: Morinda lucida (Oruwo), Enantia chlorantha (Awopa), Alstonia boonei (Ahun), Azadirachta indica (Dongoyaro) and Khaya grandifoliola (Oganwo) plants were found to be in use for malaria therapy at Okeigbo, Southwest, Nigeria . The parts of plants used could either be the barks, roots, leaves or whole plants. The recipes also, could be a combination of various species of plants or plant parts. This study highlights potential sources for the development of new antimalarial drugs from indigenous medicinal plants found in Okeigbo, Nigeria

    Content familiarity, attitude and achievement in dramatic literature-in-English in Nigeria

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    This study examined content familiarity and attitude as predictors of student’s achievement in dramatic Literature-in-English language. This study adopted a descriptive survey design. Three hundred and four students of Literature-in-English language, purposively and randomly selected, were involved in the study. Four research questions guided this study. The instruments used were Dramatic Literature-in-English Achievement Test (DLEAT), Content Familiarity Test (CFT) and Questionnaire on Students’ Attitude to Dramatic Literature-in-English (QSADLE). Data obtained were analyzed using multiple regression analysis. The results showed that there was a positive relationship between content familiarity and achievement (r= 0.35, P<0.05); the two factors had a positive moderate multiple relationship with students’ achievement (R=.44); content familiarity ((β=.15) made the highest contribution to achievement (β=.35), followed by attitude to dramatic Literature in English (β=-.04). The results further showed that content familiarity (β =.18, t= 2.35, P<.05) could predict students’ achievement in dramatic Literature in English. Based on the findings of the research, it is recommended that school authorities and the government should make available, in school libraries, literature texts that are relevant to the social and cultural environment of the students.Keywords: Dramatic literature, content familiarity and attitud

    The fabrication of nano-scale engineered surfaces to investigate the enhancement of boiling heat transfer and CHF in nuclear reactors

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    This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Thesis: S.M., Massachusetts Institute of Technology, Department of Nuclear Science and Engineering, 2019Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (pages 57-59).This work looks into the feasibility of utilizing nanotechnology in order to improve the performance of pressurized water reactors (PWRs) in the nuclear industry. Through growing zinc oxide nanowires (ZnO NW) on the surface of zircaloy, which clads the uranium oxide fuel, the project aims to increase the heat flux limit, i.e., the critical heat flux (CHF), resulting in a boiling crisis. That allows for improvement on the safety margins and operation at higher power. The exact procedure for growing the nanowires will be delineated such that the results can be replicated exactly. A variety of ZnO NW structures will be fabricated based on the characteristic size of the features and characteristic spacing among the structures. This goal will be achieved by controlling the fabrication steps at various stages. Utilizing the Scanning Electron Microscope (SEM) and Focused Ion Beam (FIB), we will be able to geometrically describe the properties of the nanowires. Heat transfer performance of ZnO nanostructured surfaces will be characterized through flow boiling at atmospheric pressure and under pressurized conditions, using state-of-the-art diagnostic systems consisting of high-speed video and infrared (IR) thermometry. The post processing of the IR data will allow us to determine spatial and temporal evolution of heat flux and temperature across the heated surface to the point of CHF. This will all culminate into a numerical result termed the enhancement, which will describe the improvement from modern standards. These results will provide useful insights into designing the future generation nuclear fuel claddings as well as economic, feasible, and scalable nanofabrication techniques.by Olorunsola J. Akinsulire, Jr.S.M.S.M. Massachusetts Institute of Technology, Department of Nuclear Science and Engineerin

    Awareness Of And Attitude To Learning Management System Among Undergraduates In University Of Ibadan, Nigeria

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     This study investigated awareness of and attitude to the Learning Management System among undergraduates at University of Ibadan, Nigeria. Two research questions were raised to guide the study. The study adopted the survey research design. The Department of English was selected from the Faculty of Art, University of Ibadan. A simple random sampling technique was used to select 50 students from 100 Level, 200 Level and 300 Level in the Department of English, University of Ibadan. In all, a total of 150 students in the English Language department participated in the study. Two research instruments were used for data collection: Students’ Awareness of the Learning Management System.  Questionnaire (r=0.76) Questionnaire on Students' Attitude to the Learning Management System (r=0.80). Data collected were analysed using descriptive statistics of percentage, mean and standard deviation. The findings of the study revealed a weighted mean of 3.31 against the threshold of 2.50 which showed that the level of awareness of undergraduate students about the learning management system was high. Also, it revealed a weighted mean of 2.56 greater than the threshold of 2.50 which showed that the majority of the selected undergraduates had a positive attitude to the learning management system. Based on the findings of the study, it was recommended that relevant educational bodies and stakeholders should ensure that both lecturers and undergraduates are aware of Learning Management System. Government should do everything possible to provide online facilities and equipment for tertiary institutions. The Academic Staff Union of Nigerian Universities (ASUU) and other educational bodies should organise seminars, workshops and conferences on how to use online platforms to teach English Language courses effectively
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