Riskscapes and Sexscapes: the Socio-Spatial Dialectics of Brothels in Ogbomoso, Nigeria

The state of anomie in cities has induced several sociological problems that are place and space specific. Against this background, the study assesses the socio-environmental effects of brothels in Ogbomoso, Nigeria. The study identifies the social and environmental characteristics of brothels, evaluate the behavioral attitudes of residents in the selected neighborhoods including morals, culture, norms, values, etc, and assess relationships between existence of brothels and the moral/ behavioral attitudes of residents in their neighborhood. Both the primary and secondary data were used. A structured questionnaire was administered to 67 respondents, pro-rata at the ratio of 17:17:33, in the three zones at each of the seven brothel areas. The study thus used a multi-stage sampling procedure. Descriptive and inferential statistics were used. Chi-square and ANOVA were used to explain the difference in the characteristics of resident between and among the zones on the one hand and among the brothel areas on the other. Linear regression analysis was used to explain the relationship between environmental characteristics and social behavior of the residents. The study observed that there is a reliable relationship (R = .973) between the location of brothels and socially unacceptable behavior among residents. This observation do not differ significantly among the brothel areas but among the zones; indicating the distances from brothels. The study thus recommends an aggressive planning that incorporates sociological considerations in the ordering of the use of land. Keywords: Riskscapes, Sexscapes, Brothels, Environmental Characteristics, Social Behavio

Analyzing the Impact of Heat and Mass Transfer on Unsteady MHD Flow with Thermal Radiation and Binary Chemical Reaction

In this paper, we investigate the combined effects of heat and masstransfer on unsteady oscillatory magnetohydrodynamic (MHD) flow withthermal radiation and binary chemical reaction. The governing equationsof the flow field, energy equation, and species concentration equation arederived under the assumptions of incompressible flow, uniform magneticfield, and small amplitude oscillations. The influence of thermal radiation and chemical reaction is incorporated through appropriate boundary conditions. Mathematical formulations are presented for the coupled systemof equations, and numerical simulations are conducted to analyze the heatand mass transfer characteristics of the flow. Sensitivity analysis of the governing parameters were conducted and presented through graphs and discussed. The results provide insightsinto the complex interplay between fluid dynamics, thermal radiation, andchemical reaction in MHD systems and their implications for engineeringapplications.&nbsp

PERFORMANCE AND CARCASS CHARACTERISTICS OF FINISHING BROILERS FED DIETS SUPPLEMENTED WITH COMBINATION OF PROBIOTICS (B. cereus) AND PREBIOTICS (MANNOSE [MOS])

The experiment aimed to investigate effect of combination of probiotics and prebiotics on the performance and carcass characteristics of broilers at finishing phase. A total number of 300 day-old Anak broiler chicks were used to determine the response of broiler chicks to diets supplemented with probiotics (Bacillus cereus) and prebiotics (Mannose). The chicks were randomly allotted to four treatment groups of 75 birds with 25 birds per replicate in a completely randomized design. The four dietary treatments comprised 500ppm MOS; 250ppm B. cereus + 500ppm MOS; 500ppm B. cereus + 500ppm MOS and 750ppm B. cereus + 500ppm MOS, respectively. Results showed that feed conversion ratio decreased significantly (P< 0.05) from 1.21 for groups fed det supplemented with 250ppm B. cereus + 500ppm MOS to 1.05 for groups fed with 750ppm B. cereus + 500ppm MOS  as more prebiotics were added to the probiotics. Final live weight, eviscerated weight and dressing percentage were significantly (p<0.05) influenced by combination of probiotics and prebiotics in finishing broilers. Final live weight values ranged from 2453.30g in birds fed 250ppm B. cereus + 500ppm MOS  to 2488.30g in birds fed 750ppm B. cereus  + 500ppm MOS, while eviscerated weight ranged from 1063.30g at 500ppm MOS to 1396.70g  at 750ppm B. cereus + 500ppm MOS. The same trend was observed for dressing percentage, neck, whole gizzard and liver. It was concluded that combination of probitics and prebiotics at 750ppm B. cereus + 500ppm MOS had positive effect on growth performance and carcass qualities of broilers at finishing phase. &nbsp

Mathematical Analysis of Spread and Control of Diphtheria with Emphasis on Diphtheria Antitoxin Efficiency

Diphtheria, a bacterial infection caused by Corynebacterium diphtheriae, remains a significant public health concern worldwide. In this study, we employ mathematical modeling to analyze the spread and control of diphtheria, focusing on the efficacy of Diphtheria Antitoxin in mitigating the disease's impact. Through the development of compartmental models, system of differential equations governing the dynamics was formulated. Due to the complexity and non-linearity of the dynamics, a numerical solutions that utilizes Runge-Kutta Fehlberg order 4 and 5 method. The dynamics of diphtheria transmission and the potential impact of DAT administration on disease outcomes was investigate. Our findings highlight the critical role of Antitoxin efficiency in reducing disease burden, preventing severe cases, and containing epidemic spread. By exploring various scenarios and parameter sensitivities, we provide insights into optimal control strategies and intervention measures to combat diphtheria outbreaks effectively. This research contributes to a better understanding of diphtheria epidemiology and informs public health policies aimed at enhancing vaccination coverage and DAT availability to achieve sustainable disease control and prevention.&nbsp

Estimating the prevalence of COPD in an African country:evidence from southern Nigeria

# BACKGROUND: Though several environmental and demographic factors would suggest a high burden of chronic obstructive pulmonary disease (COPD) in most African countries, there is insufficient country-level synthesis to guide public health policy. # METHODS: A systematic search of MEDLINE, EMBASE, Global Health and African Journals Online identified studies reporting the prevalence of COPD in Nigeria. We provided a detailed synthesis of study characteristics, and overall median and interquartile range (IQR) of COPD prevalence in Nigeria by case definitions (spirometry or non-spirometry). # RESULTS: Of 187 potential studies, eight studies (6 spirometry and 2 non-spirometry) including 4,234 Nigerians met the criteria. From spirometry assessment, which is relatively internally consistent, the median prevalence of COPD in Nigeria was 9.2% (interquartile range, IQR: 7.6–10.0), compared to a lower prevalence (5.1%, IQR: 2.2–15.4) from studies based on British Medical Research Council (BMRC) criteria or doctor’s diagnosis. The median prevalence of COPD was almost the same among rural (9.5%, IQR: 7.6–10.3) and urban dwellers (9.0%, IQR: 5.3–9.3) from spirometry studies. # CONCLUSIONS: A limited number of studies on COPD introduces imprecision in prevalence estimates and presents concerns on the level of response available across different parts of Nigeria, and indeed across many countries in sub-Saharan Africa

Comparative antioxidant activity, total phenol and total flavonoid contents of two Nigerian ocimum species

Antioxidants are compounds which act as a major defense against oxidative stress caused by free radicals. In this study, a comparative evaluation of the antioxidant properties, phenolic and flavonoid contents of the methanolic extracts of Ocimum gratissimum Linn and Ocimum canum Sims was carried out. Crude extracts of both plants were obtained by maceration of powdered plant materials in methanol (80%) for 24hrs. The phenolic and flavonoid contents were determined using standard methods while the antioxidant capacities were evaluated using six different in vitro radical scavenging assays: total antioxidant potential, reductive potential, I, 1-diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging, lipid peroxidation inhibition, hydroxyl radical and nitric oxide scavenging activity. The total phenolic content in O. gratissimum and O. canum were found to be 32.66 ± 6.21 and 17.19 ± 2.54 mg GAE/g dw while total flavonoid content gave 1.94 ± 0.23 and 0.67 ± 0.01 mg QUE/g dw, respectively. Both extracts had effective reductive potential as well as exhibited strong total antioxidant capacity with increasing concentration of extract. Comparatively, O. gratissimum exhibited a significantly (p < 0.05) higher capacity to quench the DPPH free radical with IC50 value of 26.01 ± 3.2 µg/ml than O. canum, which has an IC50 value of 60.45 ± 5.22 µg/m. O. gratissimum also significantly inhibited membrane lipid peroxidation and hydroxyl radical formation with IC50 of 99.37 ± 8.56 µg/ml and 465.33 ± 21.62 µg/ml, respectively while O. canum correspondingly gave IC50 values of 447.5 ± 35.61 µg/ml and 868.16 ± 43.05 µg/ml. In the nitric oxide scavenging activity, however, O. canum showed a stronger inhibitory effect than O. gratissimum as indicated by their IC50 values of 277.22 ± 15.09 µg/ml and 731 ± 56.99 µg/ml, respectively. These activities are however several folds lower than those of butylated hydroxyl toluene (BHT), ascorbic acid and quercetin used as antioxidant standards. The results demonstrate that O. gratissimum has greater antioxidant capacity than O. canum because of its relatively higher radical scavenging activity in all antiradical tests carried out except the nitric acid scavenging test and higher contents of flavonoid and phenolic compounds. O. gratissimum is therefore more beneficial therapeutically than O. canum since it provides better defense against free radical induced oxidative stress, and this attribute probably explains its relative preference in ethnomedicine for both culinary and medicinal purposes amongst the Ocimum species widely cultivated in South Western Nigeria

High cases of submicroscopic Plasmodium falciparum infections in a suburban population of Lagos, Nigeria.

BACKGROUND: Asymptomatic malaria parasites are significant sources of infections for onward malaria transmission. Conventional tools for malaria diagnosis such as microscopy and rapid diagnostic test kits (RDT) have relatively low sensitivity, hence the need for alternative tools for active screening of such low-density infections. METHODS: This study tested var acidic terminal sequence-based (varATS) quantitative polymerase chain reaction (qPCR) for screening asymptomatic Plasmodium falciparum infections among dwellers of a sub-urban community in Lagos, Nigeria. Clinically healthy participants were screened for malaria using microscopy, RDT and varATS qPCR techniques. Participants were stratified into three age groups: 1-5, 6-14 and > 14 years old. RESULTS: Of the 316 participants screened for asymptomatic malaria infection, 78 (24.68%) were positive by microscopy, 99 (31.33%) were positive by RDT and 112 (35.44%) by varATS qPCR. Participants aged 6-14 years had the highest prevalence of asymptomatic malaria, with geometric means of ~ 116 parasites/µL and ~ 6689 parasites/µL as detected by microscopy and varATS, respectively. CONCLUSION: This study has revealed high prevalence of asymptomatic malaria in the study population, with varATS detecting additional sub-microscopic infections. The highest concentration of asymptomatic malaria was observed among school-age children between 6 and 14 years old. A large-scale screening to identify other potential hotspots of asymptomatic parasites in the country is recommended

High Energy Physics Opportunities Using Reactor Antineutrinos

Nuclear reactors are uniquely powerful, abundant, and flavor-pure sources ofantineutrinos that continue to play a vital role in the US neutrino physicsprogram. The US reactor antineutrino physics community is a diverse interestgroup encompassing many detection technologies and many particle physicstopics, including Standard Model and short-baseline oscillations, BSM physicssearches, and reactor flux and spectrum modeling. The community's aims offerstrong complimentary with numerous aspects of the wider US neutrino program andhave direct relevance to most of the topical sub-groups composing the Snowmass2021 Neutrino Frontier. Reactor neutrino experiments also have a directsocietal impact and have become a strong workforce and technology developmentpipeline for DOE National Laboratories and universities. This white paper,prepared as a submission to the Snowmass 2021 community organizing exercise,will survey the state of the reactor antineutrino physics field and summarizethe ways in which current and future reactor antineutrino experiments can playa critical role in advancing the field of particle physics in the next decade.<br