171 research outputs found

    Cemento compuesto de alta resistencia al sulfato de magnesio

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    This study investigates the magnesium sulphate resistance of chemically activated phosphorus slag-based composite cement (CAPSCC). Enough mortar specimens were prepared from phosphorus slag (80 wt.%), type II Portland cement (14 wt.%), and compound chemical activator (6 wt.%) and were exposed to 5% magnesium sulphate solution after being cured. Mortar specimens of both type II and V Portland cements (PC2 and PC5) were also prepared and used for comparison purpose. According to the test results, after 12 months of exposure, PC2, PC5 and CAPSCC exhibited 43.5, 35.2 and 25.2% reduction in compressive strength, 0.136, 0.110, and 0.026% expansion in length, and 0.91, 2.2, and 1.78% change in weight, respectively. Complementary studies by X-ray diffractometry and scanning electron microscopy revealed that CAPSCC has a very low potential for the formation of sulphate attack products, especially ettringite. The results confirm a high magnesium sulphate resistance for CAPSCC compared to PC2 and PC5.Este trabajo aborda el estudio de la resistencia al sulfato de magnesio de un cemento compuesto con base de escoria de fósforo activada químicamente (CAPSCC). Se prepararon muestras de mortero a partir de escoria de fósforo (80% en peso), cemento Portland tipo II (14% en peso) y activador químico (6% en peso) y tras el curado, se expusieron a una solución de sulfato de magnesio al 5%. También se prepararon morteros de cementos Portland de tipo II y V (PC2 y PC5) que se usaron con fines comparativos. De acuerdo a los resultados obtenidos, después de 12 meses de exposición, PC2, PC5 y CAPSCC mostraron un 43.5, 35.2 y 25.2% de reducción en la resistencia a la compresión, 0.136, 0.110, y 0.026% de expansión en longitud, y 0.91, 2.2 y 1.78% de cambio en peso, respectivamente. Estudios complementarios por difracción de rayos X y microscopía electrónica de barrido revelaron que los cementos CAPSCC tienen un potencial muy bajo para la formación de productos de ataque de sulfato, especialmente etringita. Los resultados confirman una alta resistencia al sulfato de magnesio para CAPSCC en comparación con PC2 y PC

    Polymorphisms of plasminogen activator inhibitor-1, angiotensin converting enzyme and coagulation factor XIII genes in patients with recurrent spontaneous abortion

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    We investigated polymorphisms of plasminogen activator inhibitor-1 (PAI-1), angiotensin converting enzyme (ACE ) and coagulation factor XIII (FXIII) genes and their association with recurrent spontaneous abortion (RSA) in Iranian patients and normal healthy controls. Ten (18.5%) patients were homozygote (4G/4G) for PAI-1 polymorphism, in contrast with two (2%) controls (p = 0.001). Patients with homozygote 4G mutation were significantly more prone to RSA in contrast to others (odds ratio: 11.0, 95% CI: 2.3-52.4). Nineteen (30.2%) patients and 25 (26.6%) controls were homozygote (DD) for ACE polymorphism. We observed only two patients and one control with homozygosity (34leu) for FXIII polymorphism. 4G/4G polymorphism for PAI-1 gene could be a thrombophilic mutation leading to abortion in Iranian population

    Fishing trend and fisheries potential analyses for the Persian Gulf and Sea of Oman, 1973-2003

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    Catch data from Persian Gulf and Sea of Oman during 1973 to 2001 were used to assess the state of the fishery development in these ecosystems. Also, fishery trends were analyzed to determine catch fluctuations during the period. Catch trend for each species from 1997 to 2003 was analyzed and fishing potential of the species for the following year was predicted. Based on the assessments, we can summarize fishing development in the southern waters of Iran into three periods: undeveloped, rapid development stage and developed stage. The undeveloped stage continued till early 1981, continued by a rapid stage until 1997, reaching to maximum level of at this year and continuing ever since. Catch trend analyses for each species during 1997 to 2003 showed different patterns for each species depending on its economic value. However, the mean catch of all species showed a sustainable trend in the two marine ecosystems. It is concluded that the catch quantity for most of the species have already reached a maximum level. Therefore, in order to keep fisheries sustainable in the region, excess fishing should be avoided

    Paradox of Modern Pregnancy: A Phenomenological Study of Women's Lived Experiences from Assisted Pregnancy

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    The purpose of our study was describing the meaning of pregnancy through Assisted Reproductive Technologies (ARTs). A qualitative design with hermeneutic phenomenology approach was selected to carry out the research. Semistructured in-depth interviews were conducted with 12 women who experienced assisted pregnancy. Three themes emerged from women's experience including finding peace in life, paradoxical feelings, and struggling to realize a dream. We concluded that pregnancy is the beginning of a new and hard struggle for women with fertility problems. The findings of our study resulted in helpful implications for the health care professionals managing assisted pregnancies. Copyright © 2015 Fahimeh Ranjbar et al

    Prevalence of torque teno virus in healthy individuals and those infected with hepatitis C virus living in Yazd, Iran

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    Background: Torque teno virus (TTV) is a non-enveloped DNA virus that its role as a helper or causative agent in hepatitis is still unclear. TTV prevalence varies in different regions of the world. This study aimed to determine the prevalence of TTV in healthy individuals and those infected with hepatitis C virus (HCV) living in Yazd city, Iran. Methods: In this case-control study, 50 healthy subjects and 68 HCV-positive individuals who referred to Yazd hospitals participated in this study. TTV DNA in serum samples were detected by nested polymerase chain reaction (PCR) using specific primers of 5?-UTR and N22 regions. The genotypes of HCV and TTV were determined by sequencing method. Results: TTV-DNA was detected in 2 out of 50 (4?) healthy individuals and in 4 out of 68 (5.8?) HCV-positive persons. There was not a significant correlation between the prevalence of TTV and HCV infection. The most common TTV genotypes among HCV-positive individuals were 3, 17 and 13, respectively. There was not a significant association obtained between HCV genotypes and TTV genotypes. Conclusion: The prevalence of TTV in Yazd province was low compared with the other areas of Iran. The prevalence of TTV in HCV infected people was not significantly higher than its rate in uninfected individuals. © 2020 Caspian Journal of Internal Medicine. All rights reserved

    Causes of bimodal melting curve:Asymmetric guaninecytosine (GC) distribution causing two peaks in melting curve and affecting their shapes

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    The aim of this study was to present a new situation in which a relatively single short PCR-product might show two separate peaks with sequence specific shapes at the dissociation curve. SYBR-Green I real-time RT-PCR was performed on Lhcgr-gene transcripts in rats. Different programs were used for melting curve simulation and estimating Tm. Statistical tests were performed to determine whether two peaks at the dissociation curve were belonging to a single template. A bimodal melting curve was observed in real-time RT-PCR on a short segment (169 bp) of Lhcgr gene with a single band in gel electrophoresis. Sequencing of the Cloned PCR-product was compatible with template sequence. Realtime PCR using the vector conveying interested sequence, showed again two peaks at dissociation curve. The GC-content of first 100 bases (75%) and last 69 bases (42%) were significantly different. DNA melting simulation programs also confirmed the bimodal pattern, although, their height and wideness were different to actual peaks. Due to the asymmetric GC distribution effect on dissociation curve in short sequences, it is highly recommended to use DNA melting simulation programs to predict the number of peaks in the melting curve when designating primers; however, predicted peak shapes are not always accurate.Key words: Asymmetric GC distribution, bimodal melting curve, DNA melting simulation, SYBR-green I realtime PCR

    A multilingual gold-standard corpus for biomedical concept recognition: the Mantra GSC

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    Objective To create a multilingual gold-standard corpus for biomedical concept recognition. Materials and methods We selected text units from different parallel corpora (Medline abstract titles, drug labels, biomedical patent claims) in English, French, German, Spanish, and Dutch. Three annotators per language independently annotated the biomedical concepts, based on a subset of the Unified Medical Language System and covering a wide range of semantic groups. To reduce the annotation workload, automatically generated preannotations were provided. Individual annotations were automatically harmonized and then adjudicated, and cross-language consistency checks were carried out to arrive at the final annotations. Results The number of final annotations was 5530. Inter-annotator agreement scores indicate good agreement (median F-score 0.79), and are similar to those between individual annotators and the gold standard. The automatically generated harmonized annotation set for each language performed equally well as the best annotator for that language. Discussion The use of automatic preannotations, harmonized annotations, and parallel corpora helped to keep the manual annotation efforts manageable. The inter-annotator agreement scores provide a reference standard for gauging the performance of automatic annotation techniques. Conclusion To our knowledge, this is the first gold-standard corpus for biomedical concept recognition in languages other than English. Other distinguishing features are the wide variety of semantic groups that are being covered, and the diversity of text genres that were annotate

    Genetic variation of Mehraban sheep using two intersimple sequence repeat (ISSR) markers

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    Genetic diversity within Mehraban sheep populations, as one of the main breeds of Iranian sheep, was studied using (AG)9C and (GA)9C as two inter-simple sequence repeat (ISSR) markers. Blood samples were collected from 210 animals in 6 flocks, 35 heads each, in different parts of Hamedan province. In the polymerase chain reaction (PCR) products, (AG)9C and (GA)9C primers amplified 28 and 36 fragments, respectively, which ranged from 100 to more than 3100 bp. Percentages of polymorphic bands in the different populations ranged from 69 to 77%. In the pooled population, all inter-simple sequence repeat (ISSR) fragments were polymorphic. Shannon and Nei gene diversity indices were 0.2256 and 0.1258, respectively, which indicated low genetic diversity of Mehraban sheep. The population studied was at Hardy-Weinberg equilibrium for most of the ISSR-loci. Analysis of molecular variance (AMOVA) partitioned the ISSR variation into inter and intra population components, where inter-populations and intra-populations accounted for 9 and 91% of the total variation, respectively. The results of this study showed that the Mehraban sheep is a pure native breed that has a low genetic diversity between subpopulations and could be noticed for its potentials in response to selection or crossing with other breeds.Key words: Inter-simple sequence repeat (ISSR) markers, Mehraban sheep, genetic diversity

    The effect of Setarud (IMOD�) on angiogenesis in transplanted human ovarian tissue to nude mice

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    Background: One of the promising methods in fertility preservation among women with cancer is cryopreservation of ovarian cortex but there are many drawbacks such as apoptosis and considerable reduction of follicular density in the transplanted ovary. One solution to reduce ischemic damage is enhancing angiogenesis after transplantation of ovarian cortex tissue. Objective: The aim of this study was to investigate the effect of Setarud, on angiogenesis in transplanted human ovarian tissue. Materials and Methods: In this case control study, twenty four nude mice were implanted subcutaneously, with human ovarian tissues, from four women. The mice were randomly divided into two groups (n=12): the experimental group was treated with Setarud, while control group received only vehicle. Each group was divided into three subgroups (n=4) based on the graft recovery days post transplantation (PT). The transplanted fragments were removed on days 2, 7, and 30 PT and the expression of Angiopoietin-1, Angiopoietin-2, and Vascular endothelial growth factor at both gene and protein levels and vascular density were studied in the grafted ovarian tissues. Results: On the 2nd and 7th day PT, the level of Angiopoietin-1 gene expression in case group was significantly lower than that in control group, while the opposite results were obtained for Angiopoietin-2 and Vascular endothelial growth factor. These results were also confirmed at the protein level. The density of vessels in Setarud group elevated significantly on day 7 PT compared to pre-treatment state. Conclusion: Our results showed that administration of Setarud may stimulates angiogenesis in transplanted human ovarian tissues, although further researches are needed before a clear judgment is made. � 2015, Research and Clinical Center for Infertitlity. All rights reserved

    Erasmus MC at CLEF eHealth 2016: Concept recognition and coding in French texts

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    We participated in task 2 of the CLEF eHealth 2016 chal-lenge. Two subtasks were addressed: entity recognition and normalization in a corpus of French drug labels and Medline titles, and ICD-10 coding of French death certificates. For both subtasks we used a dictionary-based approach. For entity recognition and normalization, we used Peregrine, our open-source indexing engine, with a dictionary based on French terms in the Unified Medical Language System (UMLS) supplemented with English UMLS terms that were translated into French with automatic translators. For ICD-10 coding, we used the Solr text tagger, together with one of two ICD-10 terminologies derived from the task training ma-terial. To reduce the number of false-positive detections, we implemented several post-processing steps. On the challenge test set, our best system obtained F-scores of 0.702 and 0.651 fo
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