4 research outputs found

    ΠžΡ†Π΅Π½ΠΊΠ° индСкса коморбидности Ρƒ Π’Π˜Π§-ΠΈΠ½Ρ„ΠΈΡ†ΠΈΡ€ΠΎΠ²Π°Π½Π½Ρ‹Ρ… ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² Π΄ΠΎ Π½Π°Ρ‡Π°Π»Π° АРВ

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    The purpose of the study: To evaluate comorbid conditions in patients with HIV-infection.Materials and methods. The study included 779 HIV-infected patients, over 18 years old, identified in different years before the start of ART, who are on dispensary registration at the republican center for combating AIDS, were examined. The analysis of the age structure, the stage of HIV infection of patients and the analysis of the comorbidity index (CI) depending on the age and the number of CD4 lymphocytes before the start of antiretroviral therapy (ART) were conducted. The main predominant secondary and concomitant diseases were identified. CI of patients were evaluated by using the Charlson index to assess the long-term prognosis of patients.As a result of the study, it was revealed that the majority of patients had comorbid diseases (82%), which is associated with high CI. High CI was detected as increasing patients` age (CI 6 or more in 85% of patients over 60 years of age). However, 59.25% of patients under 40 years had CI 6 or more points, which was associated with a poor prognosis of life.ЦСль: ΠΎΡ†Π΅Π½ΠΈΡ‚ΡŒ ΠΊΠΎΠΌΠΎΡ€Π±ΠΈΠ΄Π½Ρ‹Π΅ состояния Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с Π’Π˜Π§-ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠ΅ΠΉ.ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. Π’ исслСдованиС Π±Ρ‹Π»ΠΈ Π²ΠΊΠ»ΡŽΡ‡Π΅Π½Ρ‹ 779 Π’Π˜Π§-ΠΈΠ½Ρ„ΠΈΡ†ΠΈΡ€ΠΎΠ²Π°Π½Π½Ρ‹Ρ… ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² ΡΡ‚Π°Ρ€ΡˆΠ΅ 18 Π»Π΅Ρ‚, выявлСнных Π² Ρ€Π°Π·Π½Ρ‹Π΅ Π³ΠΎΠ΄Ρ‹ Π΄ΠΎ Π½Π°Ρ‡Π°Π»Π° антирСтровирусной Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ, находящихся Π½Π° диспансСрном ΡƒΡ‡Π΅Ρ‚Π΅ Π² РСспубликанском Ρ†Π΅Π½Ρ‚Ρ€Π΅ ΠΏΠΎ Π±ΠΎΡ€ΡŒΠ±Π΅ со Π‘ΠŸΠ˜Π”. ΠŸΡ€ΠΎΠ²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· возрастной структуры ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² ΠΈ стадии Π’Π˜Π§-ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ, Π°Π½Π°Π»ΠΈΠ· индСкса коморбидности Π² зависимости ΠΎΡ‚ возраста ΠΈ количСства Π‘D4-Π»ΠΈΠΌΡ„ΠΎΡ†ΠΈΡ‚ΠΎΠ² Π΄ΠΎ Π½Π°Ρ‡Π°Π»Π° антирСтровирусной Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ, выявлСны основныС ΠΏΡ€Π΅ΠΎΠ±Π»Π°Π΄Π°ΡŽΡ‰ΠΈΠ΅ Π²Ρ‚ΠΎΡ€ΠΈΡ‡Π½Ρ‹Π΅ ΠΈ ΡΠΎΠΏΡƒΡ‚ΡΡ‚Π²ΡƒΡŽΡ‰ΠΈΡ… заболСвания. ИндСксом коморбидности ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² ΠΎΡ†Π΅Π½ΠΈΠ²Π°Π»ΠΈ с ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ индСкса Charlson для ΠΎΡ†Π΅Π½ΠΊΠΈ ΠΎΡ‚Π΄Π°Π»Π΅Π½Π½ΠΎΠ³ΠΎ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·Π° Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ….Π’ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Π΅ исслСдования Π±Ρ‹Π»ΠΎ выявлСно, Ρ‡Ρ‚ΠΎ Π±ΠΎΠ»ΡŒΡˆΠΈΠ½ΡΡ‚Π²ΠΎ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² ΠΈΠΌΠ΅Π»ΠΈ ΠΊΠΎΠΌΠΎΡ€Π±ΠΈΠ΄Π½Ρ‹Π΅ заболСвания (82%), Ρ‡Ρ‚ΠΎ ассоциировано с высоким индСксом коморбидности. Высокий индСкс коморбидности Π±Ρ‹Π» выявлСн ΠΏΠΎ ΠΌΠ΅Ρ€Π΅ ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½ΠΈΡ возраста ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² (индСкс коморбидности 6 ΠΈ Π±ΠΎΠ»Π΅Π΅ Ρƒ 85% ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² ΡΡ‚Π°Ρ€ΡˆΠ΅ 60 Π»Π΅Ρ‚). Π‘Ρ€Π΅Π΄ΠΈ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² младшС 40 Π»Π΅Ρ‚ Ρƒ 59,25% Π±Ρ‹Π» Ρ‚Π°ΠΊΠΆΠ΅ выявлСн индСкс коморбидности 6 ΠΈ Π±ΠΎΠ»Π΅Π΅ Π±Π°Π»Π»ΠΎΠ², Ρ‡Ρ‚ΠΎ Π°ΡΡΠΎΡ†ΠΈΠΈΡ€ΠΎΠ²Π°Π»ΠΎΡΡŒ с ΠΏΠ»ΠΎΡ…ΠΈΠΌ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·ΠΎΠΌ ΠΆΠΈΠ·Π½ΠΈ

    HERPESVIRAL INFECTIONS IN HIV-INFECTED PATIENTS (Overview)

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    With the progression of HIV infection, opportunistic infections join. A special place in the structure of opportunistic infections is occupied by herpesvirus infections, which manifest themselves in an immunodeficient state with various clinical, manifestations, affecting many organs and tissues, worsening the quality of life of HIV- infected patients

    HIV ASSOCIATED TUBERCULOSIS (Overview)

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    The literature review highlights the current epidemiological situation of HIV and tuberculosis co-infection in the world and in Uzbekistan. The literature data on the development of various forms of tuberculosis in HIV-infected patients, clinical manifestations of tuberculosis, peculiarities of the course, diagnosis and prevention are presented
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