The Impact of a Heroism-Themed Outreach with Title I Summer Program Students

Is it possible to teach students about heroism? This presentation will examine how a five-session intervention influenced at-risk students’ understanding of a hero. Outcomes from the study may be of interest to educators, administrators, and counselors who encourage students to find positive role models in the community

Supersymmetry without R-parity : Constraints from Leptonic Phenomenology

R-parity conservation is an {\it ad hoc} assumption in the most popular version of the supersymmetric standard model. Most studies of models which do allow for R-parity violation have been restricted to various limiting scenarios. The single-VEV parametrization used in this paper provides a workable framework to analyze phenomenology of the most general theory of SUSY without R-parity. We perform a comprehensive study of leptonic phenomenology at tree-level. Experimental constraints on various processes are studied individually and then combined to yield regions of admissible parameter space. In particular, we show that large R-parity violating bilinear couplings are not ruled out, especially for large $\tan\beta$.Comment: 56 pages Revtex with figures incorporated; typos (including transcription typo in Table II) and minor corrections; proof-read version, to appear in Phys. Rev.

Age, Differential Expectations, and Crime Desistance

We specify an individual-level model linking crime desistance to estimates of legal risk, differential expectations, degree of past success at legitimate and criminal pursuits, and age. OLS and logistic regression procedures are used to estimate the model using longitudinal data on serious, previously imprisoned offenders. As predicted, age decreases estimates of the likely payoffs from crime and legitimate employment. Contrary to predictions, age is unrelated to the perceived legal risk of renewed criminal participation. Age, past success at avoiding confinement, expectations of success from crime, and level of education are significant predictors of crime desistance. Neither the perceived legal risk of crime nor expectations of success through straight pursuits significantly predict desistance. We suggest an interpretation for these anomalous findings

De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population

De novo mutations (DNMs), or mutations that appear in an individual despite not being seen in their parents, are an important source of genetic variation whose impact is relevant to studies of human evolution, genetics, and disease. Utilizing high-coverage whole-genome sequencing data as part of the Trans-Omics for Precision Medicine (TOPMed) Program, we called 93,325 single-nucleotide DNMs across 1,465 trios from an array of diverse human populations, and used them to directly estimate and analyze DNM counts, rates, and spectra. We find a significant positive correlation between local recombination rate and local DNM rate, and that DNM rate explains a substantial portion (8.98 to 34.92%, depending on the model) of the genome-wide variation in population-level genetic variation from 41K unrelated TOPMed samples. Genome-wide heterozygosity does correlate with DNM rate, but only explains <1% of variation. While we are underpowered to see small differences, we do not find significant differences in DNM rate between individuals of European, African, and Latino ancestry, nor across ancestrally distinct segments within admixed individuals. However, we did find significantly fewer DNMs in Amish individuals, even when compared with other Europeans, and even after accounting for parental age and sequencing center. Specifically, we found significant reductions in the number of C→A and T→C mutations in the Amish, which seem to underpin their overall reduction in DNMs. Finally, we calculated near-zero estimates of narrow sense heritability (h2), which suggest that variation in DNM rate is significantly shaped by nonadditive genetic effects and the environment