Strong-Coupling Superconductivity of CeIrSi3_3 with the Non-centrosymmetric Crystal Structure

We studied the pressure-induced superconductor CeIrSi$_3$ with the non-centrosymmetric tetragonal structure under high pressure. The electrical resistivity and ac heat capacity were measured in the same run for the same sample. The critical pressure was determined to be $P_{\rm c}$ = 2.25 GPa, where the antiferromagnetic state disappears. The heat capacity $C_{\rm ac}$ shows both antiferromagnetic and superconducting transitions at pressures close to $P_{\rm c}$. On the other hand, the superconducting region is extended to high pressures of up to about 3.5 GPa, with the maximum transition temperature $T_{\rm sc}$ = 1.6 K around $2.5-2.7$ GPa. At 2.58 GPa, a large heat capacity anomaly was observed at $T_{\rm sc}$ = 1.59 K. The jump of the heat capacity in the form of ${\Delta}{C_{\rm ac}}/C_{\rm ac}(T_{\rm sc})$ is 5.7 $\pm$ 0.1. This is the largest observed value among previously reported superconductors, indicating the strong-coupling superconductivity. The electronic specific heat coefficient at $T_{\rm sc}$ is, however, approximately unchanged as a function of pressure, even at $P_{\rm c}$.Comment: This paper will be published in J. Phys. Soc. Jpn. on the August issue of 200

Microscopic Mechanism and Pairing Symmetry of Superconductivity in the Noncentrosymmetric Heavy Fermion Systems CeRhSI3_3 and CeIrSi3_3

We study the pairing symmetry of the noncentrosymmetric heavy fermion superconductors CeRhSi$_3$ and CeIrSi$_3$ under pressures, which are both antiferromagnets at ambient pressure. We solve the Eliashberg equation by means of the random phase approximation and find that the mixed state of extended s-wave and p-wave rather than the $d+f$ wave state could be realized by enhanced antiferromagnetic spin fluctuations. It is elucidated that the gap function has line nodes on the Fermi surface and the resulting density of state in the superconducting state shows a similar character to that of usual d-wave superconductors, resulting in the NMR relaxation rate $1/(T_1T)$ that exhibits no coherence peak and behaves like $1/(T_1T)\propto T^2$ at low temperatures

Breakdown of supersaturation barrier links protein folding to amyloid formation

The thermodynamic hypothesis of protein folding, known as the “Anfinsen’s dogma” states that the native structure of a protein represents a free energy minimum determined by the amino acid sequence. However, inconsistent with the Anfinsen’s dogma, globular proteins can misfold to form amyloid fibrils, which are ordered aggregates associated with diseases such as Alzheimer’s and Parkinson’s diseases. Here, we present a general concept for the link between folding and misfolding. We tested the accessibility of the amyloid state for various proteins upon heating and agitation. Many of them showed Anfinsen-like reversible unfolding upon heating, but formed amyloid fibrils upon agitation at high temperatures. We show that folding and amyloid formation are separated by the supersaturation barrier of a protein. Its breakdown is required to shift the protein to the amyloid pathway. Thus, the breakdown of supersaturation links the Anfinsen’s intramolecular folding universe and the intermolecular misfolding universe

Observation of Spin-Dependent Charge Symmetry Breaking in ΛN\Lambda N Interaction: Gamma-Ray Spectroscopy of Λ4^4_{\Lambda }He

The energy spacing between the ground-state spin doublet of $^4_\Lambda$He(1$^+$,0$^+$) was determined to be $1406 \pm 2 \pm 2$ keV, by measuring $\gamma$ rays for the $1^+ \to 0^+$ transition with a high efficiency germanium detector array in coincidence with the $^4$He$(K^-,\pi^-)$ $^4_\Lambda$He reaction at J-PARC. In comparison to the corresponding energy spacing in the mirror hypernucleus $^4_\Lambda$H, the present result clearly indicates the existence of charge symmetry breaking (CSB) in $\Lambda N$ interaction. It is also found that the CSB effect is large in the $0^+$ ground state but is by one order of magnitude smaller in the $1^+$ excited state, demonstrating that the $\Lambda N$ CSB interaction has spin dependence