Human emotional response to steering wheel vibration in automobiles

This is the post-print (final draft post-refereeing) version of the final published paper that is available from the link below. Copyright @ 2013 Inderscience Enterprises Ltd.This study investigates what form of correlation may exist between measures of the valence and the arousal dimensions of the human emotional response to steering wheel vibration and the vibration intensity metrics obtained by means of the unweighted and the frequency weighted root mean square (rms). A laboratory experiment was performed with 30 participants who were presented 17 acceleration time histories in random order and asked to rate their emotional feelings of valence and arousal using a self-assessment manikin (SAM) scale. The results suggest a highly linear correlation between the unweighted, Wh weighted and Ws weighted vibration intensity metrics and the arousal measures of the human emotional response. The results also suggest that while vibration intensity plays a significant role in eliciting emotional feelings, there are other factors which influence the human emotional response to steering wheel vibration such as the presence of high peaks or high frequency band amplitudes

Strain Measurement on Composites: Errors due to Rosette Misalignment

Electrical resistance strain gauges are increasingly used for the determination of the strain field in composite components. The effect of the angular misalignment of a strain gauge rosette on the determination of the strains in a composite material is investigated in this paper. The theoretical analysis shows that the strain error along the principal material directions depends on the difference of principal strains, on the angular misalignment of the rosette and on the angle between the maximum principal strain and the fibre direction. The paper also shows experimental evidence for the theoretical analysis

ANALISI DELLE TENSIONI RESIDUE NEI VETRI MEDIANTE FOTOELASTICITÀ RGB E LASTRA A TINTA SENSIBILE

L'analisi delle tensioni residue nel vetro viene solitamente effettuata mediante metodi fotoelastici. Questo lavoro considera l'automazione del metodo fotoelastico in luce bianca basato sull'uso congiunto della fotoelasticità RGB e di una lastra a tinta sensibile (full wave plate o tint plate), che manifesta il ritardo di un ordine di frangia, posta in serie alla lastra di vetro. Il metodo proposto è stato applicato all’analisi delle tensioni residue membranali in un vetro temperato

Photoelastic Analysis of Edge Residual Stresses in Glass by Automated “Test Fringes” Methods

Since the glass is a birefringent material, the analysis of residual stress in glass is usually carried out by means of photoelastic methods. This paper considers the automation of the “test fringes” method which is based on the use of a Babinet compensator or of a beam subjected to bending. In particular, two automated methods are proposed: the first one is based on the use of the centre fringe method in monochromatic light and the second one is based on the use of RGB photoelasticity in white light. The proposed methods have been applied to the analysis of membranal residual stresses in some tempered glasses, showing that they can effectively replace manual methods of photoelastic analysis of residual stresses in glass

Evidence of disorientation towards immunization on online social media after contrasting political communication on vaccines. Results from an analysis of Twitter data in Italy

Background In Italy, in recent years, vaccination coverage for key immunizations as MMR has been declining to worryingly low levels, with large measles outbreaks. As a response in 2017, the Italian government expanded the number of mandatory immunizations introducing penalties to unvaccinated children’s families. During the 2018 general elections campaign, immunization policy entered the political debate with the government in-charge blaming oppositions for fuelling vaccine scepticism. A new government (formerly in the opposition) established in 2018 temporarily relaxed penalties and announced the introduction of forms of flexibility. Objectives and methods First, we supplied a definition of disorientation, as the “lack of well-established and resilient opinions among individuals, therefore causing them to change their positions as a consequence of sufficient external perturbations”. Second, procedures for testing for the presence of both short and longer-term collective disorientation in Twitter signals were proposed. Third, a sentiment analysis on tweets posted in Italian during 2018 on immunization topics, and related polarity evaluations, were used to investigate whether the contrasting announcements at the highest political level might have originated disorientation amongst the Italian public. Results Vaccine-relevant tweeters’ interactions peaked in response to main political events. Out of retained tweets, 70.0% resulted favourable to vaccination, 16.4% unfavourable, and 13.6% undecided, respectively. The smoothed time series of polarity proportions exhibit frequent large changes in the favourable proportion, superimposed to a clear up-and-down trend synchronized with the switch between governments in Spring 2018, suggesting evidence of disorientation among the public. Conclusions The reported evidence of disorientation for opinions expressed in online social media shows that critical health topics, such as vaccination, should never be used to achieve political consensus. This is worsened by the lack of a strong Italian institutional presence on Twitter, calling for efforts to contrast misinformation and the ensuing spread of hesitancy. It remains to be seen how this disorientation will impact future parents’ vaccination decisions

Facilitating the driver detection of road surface type by selective manipulation of the steering-wheel acceleration signal

Copyright @ 2012 by Institution of Mechanical Engineers.Previous research has investigated the possibility of facilitating the driver detection of road surface type by means of selective manipulation of the steering-wheel acceleration signal. In previous studies a selective increase in acceleration amplitude has been found to facilitate road-surface-type detection, as has selective manipulation of the individual transient events which are present in the signal. The previous research results have been collected into a first guideline for the optimization of the steering-wheel acceleration signal, and the guideline has been tested in the current study. The test stimuli used in the current study were ten steering-wheel acceleration-time histories which were selected from an extensive database of road test measurements performed by the research group. The time histories, which were all from midsized European automobiles and European roads, were selected such that the widest possible operating envelope could be achieved in terms of the r.m.s. value of the steering acceleration, the kurtosis, the power spectral density function, and the number of transient events present in the signal. The time histories were manipulated by means of the mildly non-stationary mission synthesis algorithm in order to increase, by a factor of 2, both the number and the size of the transient events contained within the frequency interval from 20 Hz to 60Hz. The ensemble, composed of both the unmanipulated and the manipulated time histories, was used to perform a laboratory-based detection task with 15 participants, who were presented the individual stimuli in random order. The participants were asked to state, by answering 'yes' or 'no', whether each stimulus was considered to be from the road surface that was displayed in front of them by means of a large photograph on a board. The results suggest that the selectively manipulated steering-wheel acceleration stimuli produced improved detection for eight of the ten road surface types which were tested, with a maximum improvement of 14 per cent in the case of the broken road surface. The selective manipulation did lead, however, to some degradation in detection for the motorway road stimulus and for the noise road stimulus, thus suggesting that the current guideline is not universally optimal for all road surfaces

Development and characterization of an amorphous solid dispersion of furosemide in the form of a sublingual bioadhesive film to enhance bioavailability

Administered by an oral route, Furosemide (FUR), a diuretic used in several edematous states and hypertension, presents bioavailability problems, reported as a consequence of an erratic gastrointestinal absorption due to various existing polymorphic forms and low and pH-dependent solubility. A mucoadhesive sublingual fast-dissolving FUR based film has been developed and evaluated in order to optimize the bioavailability of FUR by increasing solubility and guaranteeing a good dissolution reproducibility. The Differential Scanning Calorimetry (DSC) analyses confirmed that the film prepared using the solvent casting method entrapped FUR in the amorphous state. As a solid dispersion, FUR increases its solubility up to 28.36 mg/mL. Drug content, thickness, and weight uniformity of film were also evaluated. The measured Young\ue2\u80\u99s Modulus, yield strength, and relative elongation of break percentage (EB%) allowed for the classification of the drug-loaded film as an elastomer. Mucoadhesive strength tests showed that the force to detach film from mucosa grew exponentially with increasing contact time up to 7667 N/m2. FUR was quickly discharged from the film following a trend well fitted with the Weibull kinetic model. When applied on sublingual mucosa, the new formulation produced a massive drug flux in the systemic compartment. Overall, the proposed sublingual film enhances drug solubility and absorption, allowing for the prediction of a rapid onset of action and reproducible bioavailability in its clinical application

Carboxylated-xyloglucan and peptide amphiphile co-assembly in wound healing

Hydrogel wound dressings can play critical roles in wound healing protecting the wound from trauma or contamination and providing an ideal environment to support the growth of endogenous cells and promote wound closure. This work presents a self-assembling hydrogel dressing that can assist the wound repair process mimicking the hierarchical structure of skin extracellular matrix. To this aim, the co-assembly behaviour of a carboxylated variant of xyloglucan (CXG) with a peptide amphiphile (PA-H3) has been investigated to generate hierarchical constructs with tuneable molecular composition, structure, and properties. Transmission electron microscopy and circular dichroism at a low concentration shows that CXG and PA-H3 co-assemble into nanofibres by hydrophobic and electrostatic interactions and further aggregate into nanofibre bundles and networks. At a higher concentration, CXG and PA-H3 yield hydrogels that have been characterized for their morphology by scanning electron microscopy and for the mechanical properties by small-amplitude oscillatory shear rheological measurements and compression tests at different CXG/PAH3 ratios. A preliminary biological evaluation has been carried out both in vitro with HaCat cells and in vivo in a mouse model

A CAE approach for the stress analysis of gear models by 3D digital photoelasticity

The use of numerical and experimental methods to determine the stress field of mechanical components is well known. In particular, 3D photoelasticity can be considered the only experimental technique for the complete stress state evaluation of 3D components. The advent of rapid prototyping techniques has allowed the manufacturing of complex models in a matter of hours by using birifrangent materials. The present paper is focused on the description of a Computer Aided Engineering (CAE) approach which combines Finite Element (FE) simulations and automatic photoelastic investigations for the stress analysis of face gear drives, made by stereolithography. Computer Aided Design (CAD) geometries, used to manufacture the stereolithographic models, are directly used to perform FE analyses, thus allowing the stress analysis process to become simpler and easier. The substantial agreement observed between experimental and numerical results proved the potentialities of the adopted approach and the usefulness of FE simulations to optimize photoelastic analyses through cost- and time-effective experiments even for complex 3D shapes