Towards Cost Effective Data Centers

Data Centers are sub organizations within an IT organization and form an integral part of e-enabled services infrastructure. Their effectiveness is essential for effectiveness of overall IT organization leading to efficient and effective delivery of e-services. Data Center organizations aim for Organizational Effectiveness. Many factors and measures can contribute to Organizational Effectiveness of Data Centers. This paper presents some of the findings from a research study on “Select aspects of Organizational Effectiveness of Data Centers”. As an outcome of this study, amongst other measures, Total Cost of Ownership (TCO) was derived as a critical measure for effective Data Centers. Lower TCO leads to cost effective Data Centers, leading to overall effectiveness. In this paper, we briefly introduce various measures of Data Centers’ Organizational Effectiveness and present a detailed analysis of Total Cost of Ownership (TCO) as a key measure of Data Centers’ Organizational Effectiveness. We also present various factors contributing to reduced TCO and a comparison between the factors contributing to TCO for Government and Corporate Data Centers

Homeopathic Flora of Bilaspur District of Himachal Pradesh, India: A Preliminary Survey

The present study was made in nine villages of Bilaspur district of Himachal Pradesh, a north Indian state known for its vast herbal flora. About 23 plant species belonging to 18 families used in the homeopathic system of medicine are highlighted in the present study along with their taxonomic description including botanical name, medicine name, plant part used and ailment against which the medicines are used. The collected plant specimens were identified, taxonomically defined and submitted to the herbarium for future records

Some Important Supplementary Food Plants and Wild Edible Fungi of Upper Hilly Region of District Shimla (Himachal Pradesh), India

An ethnobotanical survey of upper hilly region of Shimla was carried out in 2008 to enumerate some of the important plants used as supplementary food among the people of this area. Presence of twenty four plant species belonging to 20 genera and 14 families was documented under the present study along with 11 macrofungi belonging to 6 genera and 6 families. Generally fruits (51 %) and leaves (33%) of these plants were found to be used as supplementary food. Use of seeds, buds, stem and petiole of few plants was also observed. All the important plants and macrofungi used as supplementary food by the people of the locality are grouped on the basis of their mode of use

Phytochemical Screening and Antioxidant Activity of Methanolic Extract of Ocimum Sanctum Linn. Leaves

The phytochemicals present in plants are responsible for preventing disease and promoting health have been studied extensively to establish their efficacy and to understand the underlying mechanism of their action. Such studies have included identification and isolation of the chemical components, establishment of their biological potency both by in vitro and in vivo studies in experimental animals and through epidemiological and clinical-case control studies in man. Study findings suggest that phytochemicals may reduce the risk of coronary heart disease by preventing the oxidation of low density lipoprotein (LDL) cholesterol, reducing the synthesis or absorption of cholesterol, normalizing blood pressure and clotting, and improving arterial elasticity. Phytochemicals may detoxify substances that cause cancer. They appear to neutralize free radicals, inhibit enzymes that activate carcinogens, and activate enzymes that detoxify carcinogens. They observed that, the Ocimum sanctum Linn has also been suggested to possess, anticancer, anti-diabetic, anti-fertility, antifungal, antimicrobial, cardio protective, analgesic, antispasmodic and adaptogenic actions. Eugenol (1-hydroxy-2methoxy-4-allylbenzene) is the active constituents present in Ocimum sanctum Linn. Indian traditional shrub tulsi (Ocimum sanctums): They unique medicinal plant. They observed that, Ocimum sanctum heals many diseases chronically due to its chemical constituent and believes that it has anti- ageing, immunomodulatory property along with antimicrobial and anticancer property. Phytochemical analysis of aqueous extract of Ocimum sanctum. They observed that, the plant is known to possess antiseptic, analgesic, anti-inflammatory, antimicrobial, antistress, immunomodulatory, hypoglycemic, hypertensive and antioxidant properties. The dried powder of Tulsi (100g) was placed in the thimble of Soxhlet apparatus.500 ml of distilled water was used as a solvent

Peristaltic Induced Flow of a Two-Layered Suspension in Non-Uniform Channel

Peristaltic transport of a two-layered particulate suspension in a non-uniform channel has been investigated. The coupled differential equations for both the fluid and the particle phases in the central as well as in the peripheral layers have been solved and the expression for the flow rate, the pressure rise and the friction force has been derived. The results obtained are discussed both qualitatively and quantitatively in brief. The significance of the particle concentration as well as the peripheral layer has been well explained

Models for accessing biomedical innovation in Asia

Asian countries are striving to transition into innovation-driven economies, and healthcare is a key sector on government agendas. Strong funding at academic institutions, high-impact publications, state-of-the-art clinical infra-structures, vast talent pools, increasing start-up activities and strengthening intellectual property regimes, all aligned with coherent government policies, is creating an evolving innovation ecosystem in countries such as China, South Ko-rea, Singapore, Taiwan and India. Such factors have fuelled a desire from global pharmaceutical companies to seek in-novation in Asia. In this article, we review the varied strategies of large multinationals using two key aspects—the capital investments and operational model—to understand such diverse approaches. Based on a qualitative and quantita-tive analysis, we have classified these strategies into four distinct approaches—“Captive”, “Partner”, “Service” and “Open” models—and discussed case studies that fit into each of these clusters. The model may provide global pharma-ceutical companies with a framework to evaluate their respective approaches for sourcing innovation and align them with the operational, financial, business and strategic needs of their organizations in Asia

Assessment of clinical profile, antibiotic sensitivity and prescription pattern in blood culture positive enteric fever among pediatric and adult patients admitted in a tertiary care hospital: a prospective study

Background: Asterion Introduction: Enteric fever is a major concern in developing country. It is predominantly caused by serovars typhi and paratyphi of Salmonella enterica. Recently, an upsurge in antimicrobial resistant strains has worsened the management of enteric fever. So, aim of present study is to evaluate the clinical profile, antibiotic sensitivity and prescription pattern in blood culture proven cases of enteric fever in pediatric and adult patients.Methods: Single centre, prospective study was conducted at a tertiary care hospital. Demographic and clinical details of blood culture proven enteric fever admitted in hospital were collected over the period from August 2016 to November 2018.Results: Total 58 blood cultures grew Salmonella spp. , amongst them 84.48 % had growth of Salmonella typhi. Blood culture was sent after a mean period of 9 days and 10 days of fever in pediatric and adult patients respectively. All isolates of S. paratyphi A were pansusceptible, whereas 36.73 % isolates of S. typhi were multidrug resistant and nalidixic acid resistant. 68.97% patients received antibiotics before admission. The difference between mean time to defervescence in patients who received ceftriaxone and those who received more than one antibiotic was not statistically significant. (P value 0.87)Conclusion: Blood cultures are the important diagnostic tool to identify multidrug resistant Salmonellae. Study showed that combination therapy was not statistically superior and awareness of local antimicrobial susceptibility pattern significantly helps for better management of the patients

Nutrition Knowledge, Personal Motivation, And Food Label Use Among Indian Adults With Multiple Chronic Conditions: A Moderated Mediation Model.

Background: There has been little research conducted within developing nations examining the link between knowledge and diet-related perceptions and behaviors. In addition, prior investigations have rarely examined interrelationships between knowledge and other nutrition-related factors. Purpose: This study explored the relationship between nutrition knowledge, social/informational factors, and diet-related outcomes among Indian adults with multiple chronic conditions. Methods: A snowball sampling technique was employed to recruit individuals. Hierarchical regression analysis was employed to examine mediating and moderating relationships. Results: Results from a cross-sectional survey indicated that knowledge only predicted use among those reporting greater pressure/concern from close others. Furthermore, social support and social trust were found to moderate the relationship between knowledge and diet-related perceptions and behaviors. Discussion: Results suggest that social factors may play a critical role in moderating the impact of nutritionknowledge on diet-related perceptions and behaviors. Translation to Health Education Practice: Public Health Education interventions targeting developing nations should aim to maximize consumers\u27 nutritionknowledge while identifying valued close others who can help encourage positive health action. Furthermore, Health Educators as well as government and local communities must engage in outreach efforts to reinforce or, if necessary, change public perceptions regarding the food industry

Clinico-epidemiological profile and risk factors associated with failure of conservative therapy in pediatric empyema patients

Objective: The objective is to study the clinico-epidemiological profile and risk factors associated with failure of conservative therapy in pediatric empyema patients and to correlate the Light’s criteria in the same. Materials and Methods: A hospital-based prospective observational study was performed in the pediatric department of a tertiary care hospital, New Delhi. A total of 74 children of ≤12 years of age having either macroscopic frank pus in pleural tap or a positive Gram-stain or positive culture in pleural fluid were enrolled in the study. Those empyema patients who fail to improve with antibiotics and chest tube drainage after 7–14 days (4 weeks for Staphylococcus aureus and 6–12 weeks for anaerobic organisms, respectively) or develop some complications in the mean time were considered as a failure of therapy. Results: Head nodding, lethargy and inability to feed/drink, prior antibiotic therapy, duration of illness (>7 days) before presenting to the hospital, and growth on the cultures were the main factors associated with the failure of conservative therapy. S. aureus is the most common organism causing empyema. Considering Light’s criteria, significant results were obtained and almost all the enrolled empyema patients found to have exudative pleural fluid. In the study, failure of conservative therapy occurred in 27.03%, prolonged hospitalization was seen among 48.65 % children, 28.38% needed change in antibiotics, and 1.35% children expired. Conclusion: History of prior antibiotic therapy, long duration of illness, and clinical features at admission along with the microorganism involved affect the conservative therapy response and may predispose to complications. Light’s criteria were very well validated in the study for its use in pediatric population