A MLMVN WITH ARBITRARY COMPLEX-VALUED INPUTS AND A HYBRID TESTABILITY APPROACH FOR THE EXTRACTION OF LUMPED MODELS USING FRA

A procedure for the identification of lumped models of distributed parameter electromagnetic systems is presented in this paper. A Frequency Response Analysis (FRA) of the device to be modeled is performed, executing repeated measurements or intensive simulations. The method can be used to extract the values of the components. The fundamental brick of this architecture is a multi-valued neuron (MVN), used in a multilayer neural network (MLMVN); the neuron is modified in order to use arbitrary complex-valued inputs, which represent the frequency response of the device. It is shown that this modification requires just a slight change in the MLMVN learning algorithm. The method is tested over three completely different examples to clearly explain its generality

Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial

Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049

A Neural Network Classifier with Multi-Valued Neurons for Analog Circuit Fault Diagnosis

In this paper, we present a new method designed to recognize single parametric faults in analog circuits. The technique follows a rigorous approach constituted by three sequential steps: calculating the testability and extracting the ambiguity groups of the circuit under test (CUT); localizing the failure and putting it in the correct fault class (FC) via multi-frequency measurements or simulations; and (optional) estimating the value of the faulty component. The fabrication tolerances of the healthy components are taken into account in every step of the procedure. The work combines machine learning techniques, used for classification and approximation, with testability analysis procedures for analog circuits

Failure Prevention and Malfunction Localization in Underground Medium Voltage Cables

A smart monitoring system capable of detecting and classifying the health conditions of MV (Medium Voltage) underground cables is presented in this work. Using the analysis technique proposed here, it is possible to prevent the occurrence of catastrophic failures in medium voltage underground lines, for which it is generally difficult to realize maintenance operations and carry out punctual inspections. This prognostic method is based on Frequency Response Analysis (FRA) and can be used online during normal network operation, resulting in a minimally invasive tool. In order to obtain the good results shown in the simulation section, it is necessary to develop a lamped equivalent circuit of the network branch under consideration. The standard &pi;-model is used in this paper to analyse sections of a medium voltage cable and the parameter variations with temperature are used to classify the state of health of the line. In fact, the variation of the electrical parameters produces a corresponding variation in the frequency response. The proposed system is based on the use of a complex neural network with feedforward architecture. It processes the frequency response, allowing the classification of the cable conditions with an accuracy higher than 90%

Neurons (MLMVN) and a Backpropagation Learning Algorithm

This work is a product of the Collaborative Research Center 531, &amp;quot;Computationa