Qualitative Detection of Hepatitis C Virus in the Patients Going Through Eye Surgery

Purpose: This study was carried out to analyze the prevalence of hepatitis C Virus in patient going through eye surgery. Material and Method: This was a prospective observational study conducted at the Sindh Institute of Ophthalmology and Visual Sciences (SIOVS) Hyderabad from July 2013 to June 2015. In this study, evaluation of 5600 patients of various ages undergoing eye surgeries and being unaware of hepatitis C infection were included. Each patient was serologically screened by immunochromatography (ICT method) for qualitative detection of antibodies for Hepatitis C before surgery. Result: Two thousand two hundred sixty four (40.43%) patients were male and 3336 (59.57%) were female. Large numbers of patients were in 4th and 5th decade of life in both the sexes. Of these 5600 patients, 713 (12.73%) were serologically positive for hepatitis C antibodies. Majority of them were female (58.44%). Conclusion: The prevalence of hepatitis C antibodies positive is higher in our population. Therefore, it is mandatory to screen every patient for hepatitis C and B before any surgical procedure. The surgeon and health care professional should take protective measures. The used infected materials should be destroyed properly.

Influence of sowing dates and nitrogen levels on growth, yield and quality of scented rice cv. Pusa Sugandh-3 in Kashmir valley

A field experiment was carried out to determine the optimum sowing date and nitrogen (N) level for the scented rice cv. Pusa Sugandh-3. Twelve treatment combinations of 3 sowing dates, viz., 15th, 16th and 18th standard meteorological week (SMW) at an interval of 10 days and 4 nitrogen levels (‘0’, ‘40’, ‘60’ and ‘80’ kg N ha-1) were tested randomized in split plot design with three replications. Significant highest plant height (98.56 cm), tillers m-2 (333.41), dry matter (98.38 q ha-1), panicles m-2 (310.05), spikelets panicle-1(130.25) and grains panicle-1 (98.55), grain yield (45.2 q ha-1), harvest index (41.20 %), head rice recovery (47.5 %) and B:C ratio (3.03) were recorded for the early sown 15th SMW crop. Among the different nitrogen levels tested significant highest plant height (98.12 cm), tillers m-2 (342.33) dry matter (100.68 q ha-1), panicles m-2 (321.83), spikelets panicle-1(132.83) grains panicle-1 (96.79), grain yield (48.0 q ha-1), harvest index (42.68 %), head rice recovery (44.54 %) and B:C ratio (3.38) were recorded with the application of 80 kg N ha-1.Therefore, the variety, Pusa Sugandh-3 should be sown earlier in season from 15th to 16th SMW and with nitrogen application of 60-80 kg N ha-1 for realizing economically higher grain yield and profit under the temperate climatic conditions of Kashmir valley

Meroterpenoids: A Comprehensive Update Insight on Structural Diversity and Biology.

Funder: This research was funded by the Deanship of Scientific Research at Princess Nourah bint Abdulrahman University through the Fast-track Research Funding ProgramMeroterpenoids are secondary metabolites formed due to mixed biosynthetic pathways which are produced in part from a terpenoid co-substrate. These mixed biosynthetically hybrid compounds are widely produced by bacteria, algae, plants, and animals. Notably amazing chemical diversity is generated among meroterpenoids via a combination of terpenoid scaffolds with polyketides, alkaloids, phenols, and amino acids. This review deals with the isolation, chemical diversity, and biological effects of 452 new meroterpenoids reported from natural sources from January 2016 to December 2020. Most of the meroterpenoids possess antimicrobial, cytotoxic, antioxidant, anti-inflammatory, antiviral, enzyme inhibitory, and immunosupressive effects

Finite element approach to study the behavior of fluid distribution in the dermal regions of human body due to thermal stress

The human body is a complex structure where the balance of mass and heat transport in all tissues is necessary for its normal functioning. The stabilities of intracellular and extracellular fluids are important physiological factors responsible for homoeostasis. To estimate the effects of thermal stress on the behavior of extracellular fluid concentration in human dermal regions, a mathematical model based on diffusion equation along with appropriate boundary conditions has been formulated. Atmospheric temperature, evaporation rate, moisture concentration and other factors affecting the fluid concentration were taken into account. The variational finite element approach has been employed to solve the model and the results were interpreted graphically

Hypofractionated reirradiation by conformal radiotherapy techniques in recurrent anaplastic astrocytoma and glioblastoma multiforme: An observational study at a Tertiary Care Center in North India

Aim and Objectives: The aims and objectives of the study were to assess the progression-free survival (PFS) and overall survival, local tumor control rate (response rate), effect on the quality of life, and treatment-related toxicities in all patients diagnosed with recurrent high-grade gliomas (HGGs). Methodology: The present study was conducted between September 2017 and July 2019 in the Department of Radiation Oncology, Sheri Kashmir Institute of Medical Sciences and included a total of 22 patients. The study included recurrent HGGs (Grade III/IV) Operated Cases of Grade III and Grade IV. Results: The majority of our patients were between the age group of 40–60 years (45.5%). There were 12 males (54.5%) and 10 females (45.5%). GBM was the most common diagnosis in 13 (59.1) patients and 9 (40.9%) were anaplastic astrocytoma. Sixteen patients were diagnosed as recurrent HGG radiologically. Sixteen (72.7%) patients achieved partial response and 6 (27.3%) achieved stable disease. The median PFS was 2.8 months and the median overall survival was 4.2 months. Conclusion: Reirradiation is one of the treatment options for recurrent HGGs and conformal intensity-modulated radiotherapy can be effective treatment modality for recurrent high-grade brain tumors with only mild side effects. Although survival is better in patients with good performance status and young age

Aggregation and Rheological Behavior of the Lavender Oil–Pluronic P123 Microemulsions in Water–Ethanol Mixed Solvents

The effect of lavender oil on aggregation characteristics of P123 in aqueous-ethanolic solutions is investigated systematically by DLS, SANS, and rheology. The solubilization capacity of the P123 based formulations toward Lavender oil increased by increasing P123 concentration. The study unveiled the importance of the short chain alcohol-ethanol, as solubilization enhancer. The apparent hydrodynamic radius (<i>R</i>_h) increased significantly with an increase in lavender oil concentration up to maximum oil solubilization capacity of the copolymer at a particular ethanol concentration. DLS measurements on 5, 10, and 15 wt% P123 in the presence of 25% ethanol revealed the presence of large-sized micellar clusters in addition to the oil swollen micelles. The core size (<i>R</i>_C), radius of hard sphere (<i>R</i>_HS), and aggregation number (<i>N</i>) obtained from SANS profiles showed considerable enhancement with the addition of lavender oil confirming penetration of oil inside the copolymer. Rheological studies showed that viscosity also increased significantly with the addition of lavender oil near the maximum loading limit of the P123 concentration. Quite interestingly, the sol–gel transition temperature displayed a strong dependence on both P123 as well as oil concentration and decreased almost linearly by increasing oil concentration. This study demonstrates the use of a biocompatible and temperature sensitive self-assembled P123 based formulation for lavender oil solubilization that can be beneficial in the cosmetic industry wherein controlled release of fragrances and so forth is demanded

Leaf Color Chart (LCC)-Based Precision Nitrogen Management for Assessing Phenology, Agrometeorological Indices and Sustainable Yield of Hybrid Maize Genotypes under Temperate Climate

Excessive nitrogenous fertilization in years resulted in larger nitrogen and profit losses. This problem can be reduced by using need-based and time-specific nitrogen management. Therefore, a field experiment was carried out during the Kharif season of 2019 and 2020 in order to evaluate the impact of precision nitrogen management on the phenology, yield and agrometeorological indices of hybrid maize genotypes at the Agronomy Research Farm, FoA Wadura, Sopore, SKUAST-Kashmir. The experiment was carried out in split-plot design consisting of maize hybrids (Shalimar Maize Hybrid-2 Vivek-45 and Kanchan-517) as main plot treatments and precision nitrogen management (T1: Control, T2: Recommended N, T3: 25% N as basal ≤ LCC 3@20 kg N ha−1, T4: 25% N as basal ≤ LCC 3@30 kg N ha−1, T5: 25% N as basal ≤ LCC 4@20 kg N ha−1, T6: 25% N as basal ≤ LCC 4@30 kg N ha−1, T7: 25% N as basal ≤ LCC 5@20 kg N ha−1 and T8: 25% N as basal ≤ LCC 5@30 kg N ha−1) as sub-plot treatments. Results demonstrated that maize hybrids showed a non-significant difference in attaining different phenophases during both years. However, Shalimar Maize Hybrid-2 demonstrated higher grain (62.35 and 60.65 q ha−1) and biological yield (170.26 and 165.86 q ha−1), a higher number of days to attain different phenological stages in comparison to Vivek-45 and Kanchan-517 thereby achieved higher heat units, PTUs, HTUs, PTI. The application of nitrogen through LCC ≤ 5@30 kg N ha−1 noted higher grain yield (61.27 and 59.13 q ha−1) and biological yield (171.30 and 166.13 q ha−1) during 2019 and 2020 respectively. Higher values of Growing degree days (GDD), Heliothermal units (HTU), Photothermal units (PTU), Phenothermal index (PTI), heat use efficiency (HUE) and radiation use efficiency (RUE) were observed in the application of nitrogen through LCC ≤ 5@30 kg N ha−1 and required the highest number of days to reach different phenophases than other treatments during crop growing seasons of 2019 and 2020. The results demonstrated that Nitrogen application based on LCC ≤ 5@30 proved effective and should be adopted in maize hybrids especially in Shalimar Maize Hybrid-2 to attain higher yield under the temperate climate of Kashmir Valley

Evaluation of seedling age and nutrient sources on phenology, yield and agrometeorological indices for sweet corn (Zea mays saccharata L.)

The field experiment was conducted during Kharif season of 2020 at Agronomy farm of Faculty of Agriculture, Wadura, SKUAST-K to study the influence of age of seedling and sources of nutrients on phenology, yield and agrometeorological indices for sweet corn. The experiment included two factors viz. age of seedlings (12, 22 and 32 days old seedling) and sources of nutrients (control, RDF, 50 percent RDF + FYM @ 12 t ha−1, 50 percent RDF + vermi-compost @ 4 t ha−1 and 50 percent RDF + poultry manure @ 2 t ha−1) tested in RCBD with three replications. Transplanting 12 days old seedlings required maximum number of days to attain different phenological stages, thereby accumulated maximum heat units followed by 22 days old seedlings. While as transplanting 22 days old seedling recorded significantly highest HUE, HTUE, PTUE and HyTUE and consequently resulted in the highest green cob and biological yield compared to other ages of seedlings. Among various sources of nutrients, application of 50 per cent RDF + poultry manure @ 2 t ha−1 took maximum number of days to attain various phenophases thereby accumulated maximum heat units and registered highest HUE, HTUE, PTUE and HyTUE followed by application of 100 per cent RDF