217 research outputs found
Diagnosis and microecological characteristics of aerobic vaginitis in outpatients based on preformed enzymes
AbstractObjectiveAerobic vaginitis (AV) is a recently proposed term for genital tract infection in women. The diagnosis of AV is mainly based on descriptive diagnostic criteria proposed by Donders and co-workers. The objective of this study is to report AV prevalence in southwest China using an objective assay kit based on preformed enzymes and also to determine its characteristics.Materials and methodsA total of 1948 outpatients were enrolled and tested by a commercial diagnostic kit to investigate the AV prevalence and characteristics in southwestern China. The study mainly examined the vaginal ecosystem, age distribution, Lactobacillus amount, and changes in pH. Differences within groups were analyzed by Wilcoxon two-sample test.ResultsThe AV detection rate is 15.40%. The AV patients were usually seen in the sexually active age group of 20–30 years, followed by those in the age group of 30–40 years. The vaginal ecosystems of all the patients studied were absolutely abnormal, and diagnosed to have a combined infection [aerobic vaginitis (AV) + bacterial vaginitis (BV) 61.33%; 184/300]. Aerobic bacteria, especially Staphylococcus aureus and Escherichia coli, were predominantly found in the vaginal samples of these women.ConclusionAV is a common type of genital infection in southwestern China and is characterized by sexually active age and combined infection predominated by the AV and BV type
The development and evaluation of individualized templates to assist transoral C2 articular mass or transpedicular screw placement in TARP-IV procedures: adult cadaver specimen study
OBJECTIVES: The transoral atlantoaxial reduction plate system treats irreducible atlantoaxial dislocation from transoral atlantoaxial reduction plate-I to transoral atlantoaxial reduction plate-III. However, this system has demonstrated problems associated with screw loosening, atlantoaxial fixation and concealed or manifest neurovascular injuries. This study sought to design a set of individualized templates to improve the accuracy of anterior C2 screw placement in the transoral atlantoaxial reduction plate-IV procedure. METHODS: A set of individualized templates was designed according to thin-slice computed tomography data obtained from 10 human cadavers. The templates contained cubic modules and drill guides to facilitate transoral atlantoaxial reduction plate positioning and anterior C2 screw placement. We performed 2 stages of cadaveric experiments with 2 cadavers in stage one and 8 in stage two. Finally, guided C2 screw placement was evaluated by reading postoperative computed tomography images and comparing the planned and inserted screw trajectories. RESULTS: There were two cortical breaching screws in stage one and three in stage two, but only the cortical breaching screws in stage one were ranked critical. In stage two, the planned entry points and the transverse angles of the anterior C2 screws could be simulated, whereas the declination angles could not be simulated due to intraoperative blockage of the drill bit and screwdriver by the upper teeth. CONCLUSIONS: It was feasible to use individualized templates to guide transoral C2 screw placement. Thus, these drill templates combined with transoral atlantoaxial reduction plate-IV, may improve the accuracy of transoral C2 screw placement and reduce related neurovascular complications
The Large Sky Area Multi-object Fiber Spectroscopic Telescope (LAMOST) Quasar Survey: Quasar Properties from Data Release Six to Nine
We report the fourth installment in the series of the Large Sky Area
Multi-Object Fiber Spectroscopic Telescope (LAMOST) Quasar Survey, which
includes quasars observed between September, 2017 and June, 2021. There are in
total 13,066 quasars reliably identified, of which 6,685 are newly discovered
that are not reported in the SDSS DR14 quasar catalog or Million Quasars
catalog. Because LAMOST does not provide accurate absolute flux calibration, we
re-calibrate the spectra with the SDSS/Pan-STARRS1 multi-band photometric data.
The emission line properties of H, H, Mg\,{\sc ii} and C\,{\sc
iv}, and the continuum luminosities are measured by fitting the re-calibrated
spectra. We also estimate the single-epoch virial black hole masses () using the derived emission line and continuum parameters. This is the
first time that the emission line and continuum fluxes were estimated based on
LAMOST re-calibrated quasar spectra. The catalog and spectra for these quasars
are available online. After the nine-year LAMOST quasar survey, there are in
total 56,175 identified quasars, of which 24,127 are newly discovered. The
LAMOST quasar survey not only discovers a great number of new quasars, but also
provides a database for investigating the spectral variability of the quasars
observed by both LAMOST and SDSS, and finding rare quasars including
changing-look quasars and broad absorption line quasars.Comment: arXiv admin note: text overlap with arXiv:1811.01570, Accepted by
ApJ
Neurogenic Hypotension and Bradycardia Modulated by Electroacupuncture in Hypothalamic Paraventricular Nucleus
Electroacupuncture (EA) stimulates somatic median afferents underlying P5-6 acupoints and modulates parasympathoexcitatory reflex responses through central processing in the brainstem. Although decreases in blood pressure and heart rate by the neural-mediated Bezold-Jarisch reflex responses are modulated by EA through opioid actions in the nucleus tractus solitarius and nucleus ambiguus, the role of the hypothalamus is unclear. The hypothalamic paraventricular nucleus (PVN) is activated by sympathetic afferents and regulates sympathetic outflow and sympathoexcitatory cardiovascular responses. In addition, the PVN is activated by vagal afferents, but little is known about its regulation of cardiopulmonary inhibitory hemodynamic responses. We hypothesized that the PVN participates in the Bezold-Jarisch reflex responses and EA inhibits these cardiopulmonary responses through the PVN opioid system. Rats were anesthetized and ventilated, and their heart rate and blood pressures were monitored. Application of phenylbiguanide every 10 min close to the right atrium induced consistent depressor and bradycardia reflex responses. Unilateral microinjection of the depolarization blockade agent kainic acid or glutamate receptor antagonist kynurenic acid in the PVN reduced these reflex responses. In at least 70% of the rats, 30 min of bilateral EA at P5-6 acupoints reduced the depressor and bradycardia responses for at least 60 min. Blockade of the CCK-1 receptors converted the non-responders into EA-responders. Unilateral PVN-microinjection with naloxone reversed the EA inhibition. Vagal-evoked activity of the PVN cardiovascular neurons was reduced by 30 min EA (P5-6) through opioid receptor activation. These data indicate that PVN processes inhibitory cardiopulmonary reflexes and participates in EA-modulation of the neural-mediated vasodepression and bradycardia
CatNorth: An Improved Gaia DR3 Quasar Candidate Catalog with Pan-STARRS1 and CatWISE
A complete and pure sample of quasars with accurate redshifts is crucial for
quasar studies and cosmology. In this paper, we present CatNorth, an improved
Gaia DR3 quasar candidate catalog with more than 1.5 million sources in the
3 sky built with data from Gaia, Pan-STARRS1, and CatWISE2020. The XGBoost
algorithm is used to reclassify the original Gaia DR3 quasar candidates as
stars, galaxies, and quasars. To construct training/validation datasets for the
classification, we carefully built two different master stellar samples in
addition to the spectroscopic galaxy and quasar samples. An ensemble
classification model is obtained by averaging two XGBoost classifiers trained
with different master stellar samples. Using a probability threshold of
in our ensemble classification model and an
additional cut on the logarithmic probability density of zero proper motion, we
retrieved 1,545,514 reliable quasar candidates from the parent Gaia DR3 quasar
candidate catalog. We provide photometric redshifts for all candidates with an
ensemble regression model. For a subset of 89,100 candidates, accurate
spectroscopic redshifts are estimated with the Convolutional Neural Network
from the Gaia BP/RP spectra. The CatNorth catalog has a high purity of > 90%
while maintaining high completeness, which is an ideal sample to understand the
quasar population and its statistical properties. The CatNorth catalog is used
as the main source of input catalog for the LAMOST phase III quasar survey,
which is expected to build a highly complete sample of bright quasars with .Comment: 24 pages, 13 figures, submitted to AAS journals. Table 4 (The
CatNorth quasar candidate catalog) is available at
https://nadc.china-vo.org/res/r101313
Risk Factors for Recent Suicide Attempts in Major Depressive Disorder Patients in China: Results From a National Study
Objective: To analyze the factors associated with recent suicide attempts including socio-demographic and clinical characteristics in major depressive disorder (MDD) patients in China.Methods: The data were from a nationwide sample from 13 major psychiatric hospitals or the psychiatric units of general hospitals in China, from September 1, 2010 to February 28, 2011. Melancholic features and suicide attempts in the past month were defined according to the melancholic feature module and the suicide module of the Mini International Neuropsychiatric Interview (MINI). Socio-demographic and clinical characteristics were compared between MDD patients with and without recent suicide attempts. Further analyses regarding the factors associated with recent suicide attempts in MDD patients were performed via multivariate logistic regression analysis.Results: Among 1,172 MDD patients, 57 (4.9%) were reported to have made a suicide attempt in the past month. Compared to the MDD patients without recent suicide attempt, significantly higher percentage of patients in the recent suicide attempters group had previous suicide attempts (χ2 = 171.861, p < 0.001) and depressive episodes with melancholic features (χ2 = 22.837, p < 0.001). Logistic regression analysis indicated that previous suicide attempts (OR = 20.81, 95% CI: 11.12–38.94, p < 0.001) and depressive episodes with melancholic features (OR = 4.43, 95% CI: 2.09–9.43, p < 0.001) were independently associated with recent suicide attempts in MDD patients.Limitations: Cross-sectional design, retrospective recall of suicide attempt data.Conclusion: Recent suicide attempts are associated with melancholic features and previous suicide attempts in MDD patients in China. These data may help clinicians to identify MDD patients at high risk of suicide attempt behavior
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