1,791 research outputs found

    Evaluation of Retinol Level Among Preschool Children, Pregnant and Lactating Women Attending Primary Health Care Centres in Baghdad

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    Background: Vitamin A deficiency (VAD) is a major public health nutrition problem in the developing world. There have been no studies on this topic in Iraq. This study was designed to evaluate the serum retinol levels of preschool children, pregnant and lactating women. Objectives: The present study is an attempt to estimate the prevalence of vitamin A deficiency among preschool children, pregnant and lactating women attending primary health care centers in Baghdad, in addition to figure out the relation between vitamin A deficiency with some demographical, clinical, variables. Subjects and Methods: The study was conducted during the period from October to December 2009. The sample was comprised of 490 subjects, Lactating women pregnant women and under 6 year's old children attending ten primary health care centers in Baghdad. The data were collected through direct interview; blood samples were taken and analyze for serum retinol (SR) by HPLC analysis and hemoglobin (Hb) level, anthropometric measurement were obtained for the study sample. Results: The study showed that the prevalence of vitamin A deficiency in preschool aged children (below 6 years) was (38.3 %); and that for lactating women and pregnant women were (7.1 %) and (25 %) respectively. Forty percent of pregnant women, (25.8 %) of lactating women and a total of (58.6 %) preschool children were anemic, A correlation coefficient between SR and Hb concentrations was significant (N=490, r=0.533, P<0.0001). Conclusion: Vitamin A deficiency is a public health problem, this study shows that subjects in the 3 groups (preschool children, pregnant and lactating women) are at risk of VAD and anemia; nearly half of them had the co-occurrence of VAD and anemia. A close association between vitamin A deficiency and anemia with a correlation coefficient between SR and Hb concentrations was significant

    Presence of proline in salinized nutrient solution re-enforces the role of this amino acid in osmoregulation and protects lipid membrane peroxidation in Arabidopsis thaliana

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    Abstract Very little is known about the effect of proline addition on the accumulation of inorganic solutes (Na ) and soluble sugars in the model plant Arabidopsis thaliana. Therefore, the aim of the present study was to assess the effect of 10 mM proline (P) supply in the culture medium on water status and solute accumulation of Arabidopsis thaliana seedlings exposed to 50 mM NaCl (S). The decrease of leaf osmotic potential was more pronounced in P+S as compared to S plants, indicating that former plants were able to accumulate more compounds involved in the osmotic adjustment process. Leaf potassium concentration was reduced by 15, 21 and 25% in P, S and P+S plants respectively, as compared to the control. When compared to S or P treatments, leaf proline and soluble sugar were more accumulated under P+S treatment. Under saline conditions, exogenous proline increased leaf Na + , Ca 2+ and Mg 2+ concentrations by 27, 281 and 252%, respectively, as compared to the control. Interestingly, proline addition mitigated significantly the deleterious effects of salt on lipid membrane peroxidation. Regarding the contribution of soluble sugars to osmotic adjustment (OA), it amounted to 6% in S or P+S, plants. For proline, its contribution to OA did not exceed 3.4% under salinity (S), whereas in (P+S) treatment, it increased to 14.7%. As a whole, the positive effect of proline exogenous application under saline conditions could be partly explained by the enhanced role of this organic compound in osmoregulation and its likely protective effect against membrane lipid peroxidation

    Test beam performance of a CBC3-based mini-module for the Phase-2 CMS Outer Tracker before and after neutron irradiation

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    The Large Hadron Collider (LHC) at CERN will undergo major upgrades to increase the instantaneous luminosity up to 5–7.5×1034^{34} cm2^{-2}s1^{-1}. This High Luminosity upgrade of the LHC (HL-LHC) will deliver a total of 3000–4000 fb-1 of proton-proton collisions at a center-of-mass energy of 13–14 TeV. To cope with these challenging environmental conditions, the strip tracker of the CMS experiment will be upgraded using modules with two closely-spaced silicon sensors to provide information to include tracking in the Level-1 trigger selection. This paper describes the performance, in a test beam experiment, of the first prototype module based on the final version of the CMS Binary Chip front-end ASIC before and after the module was irradiated with neutrons. Results demonstrate that the prototype module satisfies the requirements, providing efficient tracking information, after being irradiated with a total fluence comparable to the one expected through the lifetime of the experiment

    Low exposure long-baseline neutrino oscillation sensitivity of the DUNE experiment

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    The Deep Underground Neutrino Experiment (DUNE) will produce world-leading neutrino oscillation measurements over the lifetime of the experiment. In this work, we explore DUNE's sensitivity to observe charge-parity violation (CPV) in the neutrino sector, and to resolve the mass ordering, for exposures of up to 100 kiloton-megawatt-years (kt-MW-yr). The analysis includes detailed uncertainties on the flux prediction, the neutrino interaction model, and detector effects. We demonstrate that DUNE will be able to unambiguously resolve the neutrino mass ordering at a 3σ\sigma (5σ\sigma) level, with a 66 (100) kt-MW-yr far detector exposure, and has the ability to make strong statements at significantly shorter exposures depending on the true value of other oscillation parameters. We also show that DUNE has the potential to make a robust measurement of CPV at a 3σ\sigma level with a 100 kt-MW-yr exposure for the maximally CP-violating values \delta_{\rm CP}} = \pm\pi/2. Additionally, the dependence of DUNE's sensitivity on the exposure taken in neutrino-enhanced and antineutrino-enhanced running is discussed. An equal fraction of exposure taken in each beam mode is found to be close to optimal when considered over the entire space of interest

    A Gaseous Argon-Based Near Detector to Enhance the Physics Capabilities of DUNE

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    This document presents the concept and physics case for a magnetized gaseous argon-based detector system (ND-GAr) for the Deep Underground Neutrino Experiment (DUNE) Near Detector. This detector system is required in order for DUNE to reach its full physics potential in the measurement of CP violation and in delivering precision measurements of oscillation parameters. In addition to its critical role in the long-baseline oscillation program, ND-GAr will extend the overall physics program of DUNE. The LBNF high-intensity proton beam will provide a large flux of neutrinos that is sampled by ND-GAr, enabling DUNE to discover new particles and search for new interactions and symmetries beyond those predicted in the Standard Model

    Snowmass Neutrino Frontier: DUNE Physics Summary

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    The Deep Underground Neutrino Experiment (DUNE) is a next-generation long-baseline neutrino oscillation experiment with a primary physics goal of observing neutrino and antineutrino oscillation patterns to precisely measure the parameters governing long-baseline neutrino oscillation in a single experiment, and to test the three-flavor paradigm. DUNE's design has been developed by a large, international collaboration of scientists and engineers to have unique capability to measure neutrino oscillation as a function of energy in a broadband beam, to resolve degeneracy among oscillation parameters, and to control systematic uncertainty using the exquisite imaging capability of massive LArTPC far detector modules and an argon-based near detector. DUNE's neutrino oscillation measurements will unambiguously resolve the neutrino mass ordering and provide the sensitivity to discover CP violation in neutrinos for a wide range of possible values of δCP. DUNE is also uniquely sensitive to electron neutrinos from a galactic supernova burst, and to a broad range of physics beyond the Standard Model (BSM), including nucleon decays. DUNE is anticipated to begin collecting physics data with Phase I, an initial experiment configuration consisting of two far detector modules and a minimal suite of near detector components, with a 1.2 MW proton beam. To realize its extensive, world-leading physics potential requires the full scope of DUNE be completed in Phase II. The three Phase II upgrades are all necessary to achieve DUNE's physics goals: (1) addition of far detector modules three and four for a total FD fiducial mass of at least 40 kt, (2) upgrade of the proton beam power from 1.2 MW to 2.4 MW, and (3) replacement of the near detector's temporary muon spectrometer with a magnetized, high-pressure gaseous argon TPC and calorimeter

    Snowmass Neutrino Frontier: DUNE Physics Summary

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    The Deep Underground Neutrino Experiment (DUNE) is a next-generation long-baseline neutrino oscillation experiment with a primary physics goal of observing neutrino and antineutrino oscillation patterns to precisely measure the parameters governing long-baseline neutrino oscillation in a single experiment, and to test the three-flavor paradigm. DUNE's design has been developed by a large, international collaboration of scientists and engineers to have unique capability to measure neutrino oscillation as a function of energy in a broadband beam, to resolve degeneracy among oscillation parameters, and to control systematic uncertainty using the exquisite imaging capability of massive LArTPC far detector modules and an argon-based near detector. DUNE's neutrino oscillation measurements will unambiguously resolve the neutrino mass ordering and provide the sensitivity to discover CP violation in neutrinos for a wide range of possible values of δCP\delta_{CP}. DUNE is also uniquely sensitive to electron neutrinos from a galactic supernova burst, and to a broad range of physics beyond the Standard Model (BSM), including nucleon decays. DUNE is anticipated to begin collecting physics data with Phase I, an initial experiment configuration consisting of two far detector modules and a minimal suite of near detector components, with a 1.2 MW proton beam. To realize its extensive, world-leading physics potential requires the full scope of DUNE be completed in Phase II. The three Phase II upgrades are all necessary to achieve DUNE's physics goals: (1) addition of far detector modules three and four for a total FD fiducial mass of at least 40 kt, (2) upgrade of the proton beam power from 1.2 MW to 2.4 MW, and (3) replacement of the near detector's temporary muon spectrometer with a magnetized, high-pressure gaseous argon TPC and calorimeter.Comment: Contribution to Snowmass 202

    Reconstruction of interactions in the ProtoDUNE-SP detector with Pandora

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    The Pandora Software Development Kit and algorithm libraries provide pattern-recognition logic essential to the reconstruction of particle interactions in liquid argon time projection chamber detectors. Pandora is the primary event reconstruction software used at ProtoDUNE-SP, a prototype for the Deep Underground Neutrino Experiment far detector. ProtoDUNE-SP, located at CERN, is exposed to a charged-particle test beam. This paper gives an overview of the Pandora reconstruction algorithms and how they have been tailored for use at ProtoDUNE-SP. In complex events with numerous cosmic-ray and beam background particles, the simulated reconstruction and identification efficiency for triggered test-beam particles is above 80% for the majority of particle type and beam momentum combinations. Specifically, simulated 1 GeV/cc charged pions and protons are correctly reconstructed and identified with efficiencies of 86.1±0.6\pm0.6% and 84.1±0.6\pm0.6%, respectively. The efficiencies measured for test-beam data are shown to be within 5% of those predicted by the simulation.Comment: 39 pages, 19 figure
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