Antenna servo control system characterization: Rate loop analysis for 34-m antenna at DSS 15

The elevation and azimuth servo rate loops at the 34-m High Efficiency Deep Space Station 15 (DSS 15) are described. Time and frequency response performance criteria were measured. The results are compared to theoretically deduced performance criteria. Unexpected anomalies in the frequency response are observed and identified

Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid

BACKGROUND: Staphylococcal infection of the canine epidermis and hair follicle is amongst the commonest reasons for antimicrobial prescribing in small animal veterinary practice. Topical therapy with fusidic acid (FA) is an attractive alternative to systemic therapy based on low minimum inhibitory concentrations (MICs, commonly <0.03 mg/l) documented in canine pathogenic staphylococci, including strains of MRSA and MRSP (methicillin-resistant Staphylococcus aureus and S. pseudintermedius). However, permeation of canine skin by FA has not been evaluated in detail. This study aimed to define the degree and extent of FA permeation in canine skin in vitro from two sites with different hair follicle density following application of a licensed ophthalmic formulation that shares the same vehicle as an FA-betamethasone combination product approved for dermal application in dogs. Topical FA application was modelled using skin held in Franz-type diffusion cells. Concentrations of FA in surface swabs, receptor fluid, and transverse skin sections of defined anatomical depth were determined using high-performance liquid chromatography and ultraviolet (HPLC-UV) analysis. RESULTS: The majority of FA was recovered by surface swabs after 24 h, as expected (mean ± SEM: 76.0 ± 17.0%). FA was detected within 424/470 (90%) groups of serial sections of transversely cryotomed skin containing follicular infundibula, but never in 48/48 (100%) groups of sections containing only deeper follicular structures, nor in receptor fluid, suggesting that FA does not permeate beyond the infundibulum. The FA concentration (mean ± SEM) in the most superficial 240 μm of skin was 2000 ± 815 μg/g. CONCLUSIONS: Topically applied FA can greatly exceed MICs for canine pathogenic staphylococci at the most common sites of infection. Topical FA therapy should now be evaluated using available formulations in vivo as an alternative to systemic therapy for canine superficial bacterial folliculitis.Peer reviewedFinal Published versio

Backlighting prospects for ICF targets

High energy x-ray backlighters are necessary to diagnose the implosion symmetry and stability of intermediate and high density targets. Synchronization requirements between the target irradiating pulse and the radiograph place severe constraints on the type of x-ray sources which can be used and favors laser irradiated backlighters. Data gathered on line emitters as a function of laser pulselength, wavelength and intensity in the 5 to 10 keV region are used to determine which diagnostic instruments will be feasible for ICF target experiments, and the requirements for backlighter irradiation

The Snedden-Farnsworth Exchanges of 1917 and 1918 on the Value of Music and Art in Education

In 1917 and 1918, Charles Hubert Farnsworth, a leading music educator from Teachers College, Columbia University, and David Snedden, a critic and educational theorist of national repute, privately exchanged views on the role of art and music in society and in education. Snedden mulled over Herbert Spencer's query “What knowledge is of most worth?” and concluded that music must have practical survival value: it must contribute primarily to the maintenance of social and political order and secondarily to other aims. Farnsworth, on the other hand, thought that music performance or appreciation should be for the immediate joy that it gives the individual, not for some deferred social purpose no matter how important it might be. These divergent positions are explained in light of Farnsworth's interests in philosophy and Snedden's schooling in Spencerian and Darwinian thought.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68979/2/10.2307_3345173.pd

Angel investor's selection criteria: a comparative institutional perspective

Despite the important role of angel investors as critical financial providers for new ventures, little is known regarding how institutions make their investment decisions. While angels make decisions based on selection criteria during the first stage, they are also embedded within and affected by different institutional settings and as a result weight these criteria differently than other investors. We compare angel investors' selection criteria in China and Denmark using the comparative institutional perspective. We use a policy capturing approach and hierarchy linear modeling, revealing that since Chinese angels are embedded within relationship-based institutional settings they tend to reply more on strong ties such as family and friends in management team, as well as weighting risks less compared to Danish angels operating within more rule-based institutional contexts

Lidar Based Emissions Measurement at the Whole Facility Scale: Method and Error Analysis

Particulate emissions from agricultural sources vary from dust created by operations and animal movement to the fine secondary particulates generated from ammonia and other emitted gases. The development of reliable facility emission data using point sampling methods designed to characterize regional, well-mixed aerosols are challenged by changing wind directions, disrupted flow fields caused by structures, varied surface temperatures, and the episodic nature of the sources found at these facilities. We describe a three-wavelength lidar-based method, which, when added to a standard point sampler array, provides unambiguous measurement and characterization of the particulate emissions from agricultural production operations in near real time. Point-sampled data are used to provide the aerosol characterization needed for the particle concentration and size fraction calibration, while the lidar provides 3D mapping of particulate concentrations entering, around, and leaving the facility. Differences between downwind and upwind measurements provide an integrated aerosol concentration profile, which, when multiplied by the wind speed profile, produces the facility source flux. This approach assumes only conservation of mass, eliminating reliance on boundary layer theory. We describe the method, examine measurement error, and demonstrate the approach using data collected over a range of agricultural operations, including a swine grow-finish operation, an almond harvest, and a cotton gin emission study

X-ray microscopy of laser fusion targets in four energy bands from 0.7 to 4.0 keV

A grazing x-ray microscope was shown to be able to photograph the x-ray emission from laser-produced plasmas between 0.8 and 4.0 keV with a spatial resolution of approximately 3 microns. The calibration of the x-ray mirror energy response functions and the x-ray film allow absolute measurements of the spatial and spectral distribution of the x-ray emission from laser fusion targets. (MOW

Proactive and politically skilled professionals: What is the relationship with affective occupational commitment?

The aim of this study is to extend research on employee affective commitment in three ways: (1) instead of organizational commitment the focus is on occupational commitment; (2) the role of proactive personality on affective occupational commitment is examined; and (3) occupational satisfaction is examined as a mediator and political skills as moderator in the relationship between proactive personality and affective occupational commitment. Two connected studies, one in a hospital located in the private sector and one in a university located in the public sector, are carried out in Pakistan, drawing on a total sample of over 400 employees. The results show that proactive personality is positively related to affective occupational commitment, and that occupational satisfaction partly mediates the relationship between proactive personality and affective occupational commitment. No effect is found for a moderator effect of political skills in the relationship between proactive personality and affective occupational commitment. Political skills however moderate the relationship between proactive personality and affective organizational commitment

Genome-wide diversity and phylogeography of Mycobacterium avium subsp. paratuberculosis in Canadian dairy cattle

Mycobacterium avium subsp. paratuberculosis (MAP) is the causative bacterium of Johne’s disease (JD) in ruminants. The control of JD in the dairy industry is challenging, but can be improved with a better understanding of the diversity and distribution of MAP subtypes. Previously established molecular typing techniques used to differentiate MAP have not been sufficiently discriminatory and/or reliable to accurately assess the population structure. In this study, the genetic diversity of 182 MAP isolates representing all Canadian provinces was compared to the known global diversity, using single nucleotide polymorphisms identified through whole genome sequencing. MAP isolates from Canada represented a subset of the known global diversity, as there were global isolates intermingled with Canadian isolates, as well as multiple global subtypes that were not found in Canada. One Type III and six “Bison type” isolates were found in Canada as well as one Type II subtype that represented 86% of all Canadian isolates. Rarefaction estimated larger subtype richness in Québec than in other Canadian provinces using a strict definition of MAP subtypes and lower subtype richness in the Atlantic region using a relaxed definition. Significant phylogeographic clustering was observed at the inter-provincial but not at the intra-provincial level, although most major clades were found in all provinces. The large number of shared subtypes among provinces suggests that cattle movement is a major driver of MAP transmission at the herd level, which is further supported by the lack of spatial clustering on an intra-provincial scale