783 research outputs found

    Synthesis and functionalization of carbohydrate capped silicon nanoparticles for targeting cancer cells

    Get PDF
    Silicon nanoparticles (SiNPs) hold prominent interest in various aspects of biomedical applications. For this purpose, surface functionalization of the NPs is essential to stabilize them. A facile method is reported here to synthesize highly stable and brightly luminescent amine-terminated SiNPs. The diameter of the crystal cores is 4.6 nm. The NPs emit strong blue-green photoluminescence (PL) at peak position 460 nm with quantum yield (QY) 22%. The NPs exhibited an exceptional stability over a wide pH range (4−14) and are resistant to aging over several weeks. For SiNPs to target specific disease area, and allow them to selectively bind to the cells or the bio-molecules present on the surface of the cells, carbohydrate capped SiNPs were synthesized. However, no such functionalization has been explored with SiNPs. In this study, we report the first synthesis of SiNPs functionalized with carbohydrates (Galactose, Mannose, Glucose and Lactose). The NPs show blue-green luminescence in water and orange luminescence in the dry state with emission of 600nm with the highest QY and exhibit an exceptional stability over weeks. Further study explores the possibility of using carbohydrate capped SiNPs to detect and outline various cell types on the basis of the more physiologically related carbohydrate-receptor interactions. The NPs prove to be very stable in biological media. The toxicity, which was tested both in vitro and in vivo, proved that the NPs were non-toxic. The cellular uptake efficiency was quantified by flow cytometry and indicated that the NPs internalize in the cell within 24 hours. The fluorescence uptake was quantified by both cancer and non-cancerous cell lines and the cancerous cells were shown to uptake more NPs than normal cell lines. The cellular uptake of these NPs, which was visualized by fluorescence and confocal microscopy, showed quick accumulation inside cancer cells within cytoplasm

    CHANGE IN DESIGN OF HANDLE SUPPORT FOR COST REDUCTION AND MANUFACTURING PROCESS OPTIMIZATION

    Get PDF
    Optimization of manufacturing process and cost reduction are two main factors each organization plans to achieve. Achieving these goals require knowledge about the manufacturing process and all parameters which affect manufacturing.Working on solving problems in optimization of manufacturing process ultimately helps to reduce the cost of manufacturing and in turn the cost of product with improvement in sequence of processes. The following project is carried out for designing the handle support for all ratings of electric breakers. Project was carried out by first defining general background, actual problem, existing manufacturing method, change in design, analysis of parameters which affect design, design analysis, decision, costing, implementation and conclusion. The design analysis was carried out with help of CATIA software. The outcome of project resulted in savings for the organization and also helped to improve the function of product with optimization of manufacturing processes

    India medical tourism analysis and forecasting

    Get PDF
    Mestrado APNORMedical tourism worldwide and in India is on rise. Figures of medical tourism arrivals in India for 2014, 2015 & 2016 suggest of a significant growth. The medical tourism nowadays in India is a leading player in the medical tourist/healthcare facilitation industry. It is increasingly emerging as the destination of choice for a wide range of medical procedures. There are numerous advantages of going to India for treatment. A number of actions have been taken by the Government to attract medical tourists to the country. This study was undertaken to analyse the growth trends in medical tourism in India over a period of 2014-2017 and also to project the medical tourism arrivals over the next couple of years using the sophisticated ARIMA method of trend projection. A major rise in tourist arrivals was noted in the year 2016 when the number of Medical Tourism Arrivals (MTA) shot up from 234 thousand in 2015 to 427 thousand in the year 2016. This was a rise of 83% over the last years and changed tendencies for the projections for the years to come. The made forecast for medical tourism arrivals in India for the years 2018-2020 is encouraging. The projections show a great potential for the country to earn valuable foreign exchange through medical tourism. The average figure of the forecast is 662 thousand tourists in 2018 and 791 thousand tourists in 2019 and 925 thousand tourists in 2020. India has a huge cost and expertise advantage which if leveraged through proper publicity can make it one of the leading medical tourism destinations in the days to come. The Government should step-up its efforts in this direction with aggressive publicity policies.O turismo médico em todo o mundo e na Índia está em ascensão. Os números de chegadas de turistas médicos na Índia para 2014, 2015 e 2016 sugerem um crescimento significativo. O turismo médico hoje em dia na Índia é um líder na indústria de facilitação de turismo/assistência médica. É cada vez mais emergente como o destino de escolha para uma ampla gama de procedimentos médicos. Existem inúmeras vantagens de ir à Índia para tratamento. Várias medidas foram tomadas pelo governo para atrair turistas médicos para o país. Este estudo foi realizado para analisar as tendências de crescimento no turismo médico na Índia durante um período de 2014-2017 e também para projetar as chegadas de turistas médicos ao longo dos próximos dois anos usando o sofisticado método ARIMA de projeção de tendência. Um grande aumento nas chegadas de turistas foi observado no ano de 2016 quando o número de chegadas de turistas subiu de 234 mil em 2015 para 427 mil no ano de 2016. Este foi um aumento de 83% nos últimos anos e mudou as tendências para as projeções para os anos seguintes. A previsão feita para chegadas de turistas médicos na Índia para os anos de 2018-2020 é animadora. As projeções mostram um grande potencial para o país ganhar valiosas divisas através do turismo médico. O valor médio da previsão é de 662 mil de turistas em 2018 e 791 mil de turistas em 2019 e 925 mil de turistas em 2020. A Índia tem uma vantagem enorme em termos de custo e conhecimento, que se aproveitada através de publicidade adequada pode torná-lo um dos principais destinos turísticos médicos nos próximos dias. O governo deve intensificar os seus esforços nessa direção com políticas publicitárias agressivas

    Personalizing Web Search based on User Profile

    Get PDF
    Web Search engine is most widely used for information retrieval from World Wide Web. These Web Search engines help user to find most useful information. When different users Searches for same information, search engine provide same result without understanding who is submitted that query. Personalized web search it is search technique for proving useful result. This paper models preference of users as hierarchical user profiles. a framework is proposed called UPS. It generalizes profile and maintaining privacy requirement specified by user at same time

    Amine-terminated nanoparticle films: pattern deposition by a simple nanostencilling technique and stability studies under X-ray irradiation

    Get PDF
    Exploring the surface chemistry of nanopatterned amine-terminated nanoparticle films.</p

    October is Gay History Month 2008 Flyer

    Get PDF
    This post includes the October is Gay History Month 2008 flyer and the Ms publisher file of it. Gay History month 2008; October is being gay for history; Pankaj Ahire; Joseph A Santiago; Joe Santiago; GLBT History Month highlights annually the achievements of 31 gay, lesbian, bisexual or transgender Icons—one each day—with a free video, bio, bibliography, images and oth-er resources; Gay, Lesbian, Bisexual, & Transgender Cente

    North East GLBT Group/Center List 2008

    Get PDF
    This is a compiled list all the colleges and university GLBT groups and/or Centers in the North East as of October of 2008. North East GLBT Center Listings 2008; Pankaj Ahire; Joe Santiago; Joseph A Santiago; New England Queer College Organization (NEQCO) [email protected] RHODE ISLAND: Rhode Island College – The Unity Center Phone: 401-456-8791 or 401-456-8255 Email: [email protected] Out On Campus Newsletter: [email protected]; Brown University – Queer Alliance Phone: 401-863-3062 Email: [email protected] Salve Regina University – Gay, Straight, Lesbian & Bisexual Alliance No Contact given on Website – Dir. Of Student Activities: Bart Carithers (ext.2225) Main Phone: 401-847-6650 Roger Williams; Bryant University – Bryant Pride (Student Organization) President – link provided on site Advisor: Judith McDonnell ([email protected]) Johnson and Wales University – Women’s Center (works w/ LGBTQ community) Phone: 401-598-2248; 401-598-1289 Links to email provided on site CONNECTICUT: Fairfield University - Alliance [email protected] Southern CT State University, Women’s Center (203) 392-6946 [email protected]. UCONN – Rainbow Center We are located in the Student Union on the 4th Floor, Room 403. Mailing Address: 2110 Hillside Road, Unit 3096 Storrs, CT 06269-3096 Phone: 860.486.5821 Fax: 860.486.6674 Email: [email protected] Web: http://www.rainbowcenter.uconn.edu/ Western CT State University Gay Straight Alliance Stand Together [email protected] University of Hartford Presidents Advisory Committee Jane Horvath, Chair, Associate Dean, College of Arts & Sciences [email protected] Gene Gort, Assistant Professor, Hartford Art School [email protected] Marcia Moen, Associate Professor, Arts & Sciences [email protected] Lynn Thibodeau, Information Technology Services [email protected] MASSACHUSETTS: Boston University – Spectrum [email protected] Bridgewater State College – GLBT Pride Center Lisa Forest, GLBT Coordinator GLBTA Pride Center Campus Center Room 009a [email protected] (508) 531-1408 Emerson College – The Office of GLBT Student Life [email protected] Northeastern University Gay, Lesbian, Bisexual and Transgender Advisory Group Donnie Perkins, Dean & Director Office of Affirmative Action (617) 373-2133 voice (617) 373-5814 TTY [email protected] Suffolk University - President’s Commission Wilma Busse, Chair, 617.573.8226 NEW HAMPSHIRE: Dartmouth College – Tuck Gay/Straight Alliance 100 Tuck Hall Tuck School of Business Hanover, NH 03755 Email [email protected] Plymouth State University – ALSO – the GSA of PSU [email protected] University of New Hampshire – President\u27s Commission on the Status of Gay, Lesbian, Bisexual and Transgender Issues [email protected] NEW JERSEY: Bergen Community – College GLBT Alliance President: Jamie Bussell [email protected] Advisor: Ed Mather [email protected] Advisor: Jim Bumgardner [email protected] The College of New Jersey – PRISM [email protected] (609) 771-2390 AIM: PRISMatTCNJ Rowan University – Gay Straight Alliance [email protected] PENNSYLVANIA: Bloomsburg University GLBT Office [email protected] 570-389-2819 Indiana University of Pennsylvania – University Commission on Gay, Lesbian, Bisexual and Transgender Issues Contact: Dan Burkett, Associate Professor Department of Mathematics Indiana University of Pennsylvania 219C Stright Hall Indiana, PA 15701 724.357.4761 (office) [email protected] Penn State University Rainbow Alliance Karen Kihurani, Advisor 610-396-6080 [email protected] Pete Coleman 610-396-6072 [email protected] NEW YORK: Alfred University, Spectrum (GLBT Student Group) Advisor: Vikki Eaklor 607.871.2706 [email protected]; PENNSYLVANIA: Bloomsburg University GLBT Office [email protected] 570-389-2819 Indiana University of Pennsylvania – University Commission on Gay, Lesbian, Bisexual and Transgender Issues Contact: Dan Burkett, Associate Professor Department of Mathematics Indiana University of Pennsylvania 219C Stright Hall Indiana, PA 15701 724.357.4761 (office) [email protected] Penn State University Rainbow Alliance Karen Kihurani, Advisor 610-396-6080 [email protected] Pete Coleman 610-396-6072 [email protected] NEW YORK: Alfred University, Spectrum (GLBT Student Group) Advisor: Vikki Eaklor 607.871.2706 [email protected] Bard College, Queer Alliance Contact: Elizabeth Anderson (914) 758-6822 [email protected] Barnard College, Barnard Center for Research on Women 212.854.2067 [email protected] Brooklyn Law School, Outlaws (Student Group) Bryan Levine [email protected] Ben Riskin [email protected] Colgate University, Office of LGBTQ Initiatives Center for Women\u27s Studies 315-228-7279 [email protected] [email protected] The College of Saint Rose, Multicultural Student Affairs (GLBT Issues and student group) (518) 454 – 2050 [email protected] Columbia University, Columbia Queer Alliance President: Peter Gallotta ([email protected]) Email the entire board at: [email protected] The Cooper Union, GALA (Gay and Lesbian Association)–Student Organization Dean of Students 212.353.4130 Cornell University, Lesbian, Bisexual and Gay Studies Director: Masha Raskolnikov 607.255.6480 [email protected] Fordham University, Lesbian, Gay, Bisexual and Transgender Law Students Association (LGBTLSA) Co-Chairs: Katy Schuman and Claire Black (212) 636-6968 Faculty and Alumni Liaison: Shelia Cockburn Fordham University, LGBT Group Molly Grimes, PsyD (212) 636-6228 Hamilton College, Women’s Studies Department Professor Margaret Gentry (315) 859-4282 [email protected] Hofstra University, Office of Multicultural and International Students Programs Gay Straight Alliance (516) 463-6796 Link on Website Ithaca College, Center for LGBT Education, Outreach and Services Lis Maurer, Coordinator 607-274-7394 [email protected] Jewish Theological Seminary, Gayava and the NUJLS– links for email on website: http://www.jtsa.edu/x1193.xml Manhattan College, Standing Together (student group) Advisor: Dr. Thomas Ferguson (718) 862-7137 [email protected] Manhattanville College, Gay Straight Coalition [email protected] New School University, GLBT Student Group Contact: Tanya Sielman Asst. Dir. Of Student Development 212.580.0210 x4844 [email protected] New York University, The Office LGBT Student Services (212) 998-4424 [email protected]; The Cooper Union, GALA (Gay and Lesbian Association)–Student Organization Dean of Students 212.353.4130 Cornell University, Lesbian, Bisexual and Gay Studies Director: Masha Raskolnikov 607.255.6480 [email protected] Fordham University, Lesbian, Gay, Bisexual and Transgender Law Students Association (LGBTLSA) Co-Chairs: Katy Schuman and Claire Black (212) 636-6968 Faculty and Alumni Liaison: Shelia Cockburn Fordham University, LGBT Group Molly Grimes, PsyD (212) 636-6228 Hamilton College, Women’s Studies Department Professor Margaret Gentry (315) 859-4282 [email protected] Hofstra University, Office of Multicultural and International Students Programs Gay Straight Alliance (516) 463-6796 Link on Website Ithaca College, Center for LGBT Education, Outreach and Services Lis Maurer, Coordinator 607-274-7394 [email protected] Jewish Theological Seminary, Gayava and the NUJLS– links for email on website: http://www.jtsa.edu/x1193.xml Manhattan College, Standing Together (student group) Advisor: Dr. Thomas Ferguson (718) 862-7137 [email protected] Manhattanville College, Gay Straight Coalition [email protected] New School University, GLBT Student Group Contact: Tanya Sielman Asst. Dir. Of Student Development 212.580.0210 x4844 [email protected] New York University, The Office LGBT Student Services (212) 998-4424 [email protected] Pace University, Office of Diversity Programs (GLBT Resources) 914-773-3775 [email protected] Sarah Lawrence College, Queer Variety Coalition (QVC) Contact: Ken Schneck, Assistant Dean of Student Affairs 914.395.2575 [email protected] SUNY Purchase, GLBTU (Gay, Lesbian, Bisexual Transgender Union) (914) 251-6976 Vassar College, Queer Coalition of Vassar College (845) 437-7203 [email protected] Rensselear Polytechnic Institute, Pride Aliance Advisor: Beth Guikema [email protected] President: Justin Meden [email protected] PR Officer: Marc Ebuna [email protected] St. John’s University, Gay and Lesbian Law Association President: Zoe Polk Advisor: Prof. John Barrett [email protected] City University of New York, Division of Student Affairs Dr. Esther Peralez, Vice President for Student Affairs 212.650.5426 [email protected] Mr. Carmelo Rodriguez, Director of Student Services 212.650-5426 [email protected] The Graduate Center, QUNY Contact: Karin Kohlmeier [email protected] Stony Brook University, (SUNY) LGBTA (631) 632 6469 [email protected]

    FT-IR, Thermal and Optical Studies of Gel Grown Cobalt Tartrate Crystals

    Get PDF
    The growth of cobalt tartrate crystals was achieved in silica gel by single diffusion method. Optimum conditions were established for the growth of good quality crystals. Fourier transform infrared (FT-IR) spectroscopic study indicates the presence of water molecules and suggests that tartrate ions are doubly ionized. The thermal behavior of the material was studied using thermogravimetry (TG) and differential thermal analysis (DTA). The results show that the material is thermally stable up to30 C, beyond which it decomposes through many stages till the formation of cobalt oxide at 995 C. The non linear optical behavior of these crystals is reported and explained. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3553

    Study of Growth, EDAX, Optical properties and Surface Morphology of Zinc Tartrate Crystals

    Get PDF
    Crystals of Zinc Tartrate were grown by a simple gel technique using single diffusion method. The optimum growth conditions were established by varying various parameters such as pH of gel solution, gel concentration, gel setting time, concentration of reactants etc. Crystals having different morphologies and habits were obtained. The crystals were characterized using Scanning Electron Microscope (SEM), UV, and Energy dispersive X-ray spectroscopy (EDAX). A result of the UV-Visible spectroscopy confirms nonlinear optical property of the crystals. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3027
    corecore