Penggunaan Batang Tanaman Betadin (Jatropha Mulitifida Linn) untuk Meningkatkan Jumlah Trombosit pada Mus Musculus

The use of plant stem betadin (Jatropha mulitifida Linn) to increase the number of thrombocyt in Mus musculusBackground: Jatropha multifida Linn has been used by the people of Bengkulu as an ornamental plant, some of people use as medicinal for a new wound. That is why known as betadin plants. Jatropha multifida Linn contain flavonoids compound. The aims of this study is to isolate the total flavonoids compound from stems of Jatropha multifida Linn, and then it was used to increase the number of thrombocyt.Methods: Stem Jatropha multifida Linn was isolated by EtOH (96%), the filtrate was evaporated using a rotary evaporator. Fifteen of healthy Mus musculus with 20-50 g, were grouped into 4; group 1 (P0) was treated by aquadest, group 2 (P1) was treated with 0.2 mL of palm oil, group 3 (P2) was treated with a dose of guava extract (0.028 g/kgBW), group 4 (P3) and (P4) were given total flavonoids of Jatropha multifida Linn stems in which each was given with a dose of 0.028g/kgBW and 0,056g/kgBW. After 24 hours of treatment, the thrombocyt changes owere counted under a microscope.Results: The rendement of flavonoids compound in the stem of Jatropha multifida Linn which can be isolated by EtOH is 4%. The flavonoids compound from Jatropha multifida Linn stems at a doses of 0.028 g/kgBW could increased the number of thrombocyt to 543.000/mm3 and at a 0.56 g/kgBW to 813.000/mm3.Conclusion: The flavonoids compoud from Jatropha multifida Linn stems at a doses of 0.028 g/kgBW and doses of 0.56 g/kgBWcould increased the number of thrombocyt at Mus musculus

Establishment of Learning Module based on Research of Solid Lipid Nanoparticles to Improve Biology Understanding

The goal of this study was to develop teaching materials for fat metabolism based on the effect of Caesalpinia bonduc L extracted solid lipid nanoparticles on HDL and LDL levels of Mus musculus infected with malaria and improved students’ understanding of the fat metabolism concept for Biology Education students in animal physiology courses at Bung Hatta University, Padang. The development model used is Research and Development R&D adapted from the stages (R&D) by Borg and Gall. Research conducted by analyzing the needs of students in the learning process of animal physiology in obtaining information and knowledge which used as modules for learning resources. The trial modules were conducted to 18 students of Biology Education at Bung Hatta University, Padang. The results showed that the students’ understanding of the concept of fat metabolism using the fat metabolism module was very varied, the understanding of the concept of fat metabolism was mostly categorized as good (39%), adequate (36%) and less adequate (25%). The ability to understand the concept of fat metabolism of students on the translational aspect has developed well, interpretation was sufficient while extrapolation has not developed well. This fat metabolism module improved the ability to understand the metabolic fat concepts of students of Biology Education at Bung Hatta University viewed value classically

PENGARUH MODEL PEMBELAJARAN FLIPPED CLASSROOM TERHADAP HASIL BELAJAR KIMIA SISWA PADA MATERI LARUTAN PENYANGGA DI SMAN 5 KOTA BENGKULU

The purposes of this study is to know student learning outcomes of chemistry using flipped classroom learning model and know influence of flipped classroom learning model to on buffer solution. The study was conducted in February-March of 2019 in SMAN 5 Bengkulu City This study is pre-experimental design with one-grup pretes-posttest design. Population of this study is all of XI MIPA’s student which a total of 216 students with sample of this study is XI MIPA 5’s student which a total of 36 students. Technique of sampling in this study is used with purposive sampling technique. Instrument of this study used test of learning outcomes with 20 items pretest and posttest. Analysis of the data used are mean values, normality test, homogeneity test, and t-test to the student learning outcomes. Based on normality test and homogeneity test obtained that pretest and posttest have normal distribution and distributed to homogeneous. Average value of pretest and posttest are 60,1 and 80,0. The result of hypotheses using t-test showed that value of significance is 0.000 < 0.05, so flipped classroom model influenced of significance to student learning outcomes. The result of this study showed that flipped classroom learning model can positive influence to learning outcomes and increased student learning outcomes on buffer solution in XI MIPA 5 SMA N 5 Bengkulu city on academic year of 2018/2019

Implementation of Integrated Science Model With Audiovisual Teaching Materials To Improve Students’ Learning Outcomes and Science Process Skills

This study aims to determine the effectiveness of the integrated science learning type connected to achieving basic competencies and improving science process skills. This study uses a 4-D development model that is defined, design, develop, and disseminate with one-group posttest design implemented in 5th-semester students of Chemistry Education, University of Bengkulu. The research instrument is a posttest question to measure learning outcomes and observation sheets to measure science process skills. The teaching materials used are sourced from part of the process and the results of the activity test of palm oil endophytic bacteria ethyl acetate extract against Fusarium oxysporum f.sp. by TLC-bioautography is packaged in the form of learning videos. The results showed that the Integrated Science type of Connected model was used effectively to improve student learning outcomes and science process skills

Environmental Chemistry Modules Development to Enhance Students' Creative Thinking Abilities in Heavy Metal Water Pollution Materials

Development of teaching material based on laboratory research is one way that can be done to improve students' creative thinking abilities in meeting the challenges of 21st century learning. The aims of this study are to determine the feasibility of the developed environmental chemistry modules, to improve of students' thinking abilities and determine the students’ responses to the use of modules in environmental chemistry lectures. Module development by R and D methods 4D model, namely Define, Design, Develop and Disseminate. Module quality is determined by expert validation test. Based on the results of expert validation, the module developed obtained 90.91% percentage of eligibility with a very good category. Based on the N-Gain value obtained, an increase in students' creative thinking abilities on the aspect of  flexibility was 0.47, and the aspect of elaboration was 0.64 with medium category. The student responses to the use of modules in learning enviromental chemistry obtained a percentage of 83.82% with very good category

EKSTRAKSI METABOLIT SEKUNDER DAN UJI ANTIOKSIDAN DARI DAUN MEDANG PERAWAS (Litsera Odorifera val) DENGAN METODE 1,1-DIPHENYL 2-PICRYLHIDRAZYL (DPPH)

Litseaodoriferaval.(MedangPerawas) is well recognized in Muko-Mukoregency, Bengkulu Province and used as construction material. In Serawai and Lembak Ethnic groups, it is traditionally used as medication for mouth sprue, stomachache,and boil as well as used for inducing lactation. This research aims to extract secondary metabolite compound group contained in Litseraodorifera val. leaf and to examine its antioxidant activity potency against 1,1-diphenyl 2-picrylhidrazyl (DPPH). A Fresh leaves from Litseraodorifera val. collected from Tahura Forest, Central Bengkulu area were separated into two parts: one run into chemical screeningand the second was used for extraction experiment using ethanol, ethyl acetate, hexane and acetone. Secondary metabolite compound groups contained in those extracts were tested for antioxidantactivity potency. The results showed that the extract of Litseraodorifera val. leaf contained compound group of flavonoid, saponin, tannin, phenolicand terpenoid. The extract of Litseraodorifera val. Leafincrude extract, ethyl acetate, acetone, ethanol and hexane can reduce free radical of  DPPH with IC50 of 250.7; 66.7; 69.7; 100.3 and 181.9 ppm respectively. Those are higher compared to vitamin C whose IC50 was 28.3 ppm. The extract of Litseraodorifera val. leaf haspotency as antioxidant activity that can be developed through further research

CHARACTERISTIC OF BIODISESEL AND BIODIESEL BLENDING OF OIL LOSSES FROM LIQUID WASTE OF OIL PALM FACTORY

ABSTRACT  The aim of this study was to convert oil losses from palm oil mill (POM) liquid waste into methyl ester. Methyl ester as a result of conversion process was further developed into blending biodiesel. The research was conducted through several stages: 1). insolating oil losses of POM waste which taken from PT Bio Nusantara Bengkulu. Oil losses were degummed and bleached and then the free fatty acid was determined. 2). the conversion process  of oil losses into methyl ester was done through two stages of esterification reactions; using H2SO4 catalyst at 60oC for 2 hours and transesterification using NaOH catalyst at 55oC for 2 hours. 3). Methyl ester was developed as a blending  of biodiesel,  which is a mixture of methyl ester with diesel oil, with the percentages of methyl ester of 25%, 30%, 35%, 40%, and 45%. The yield of methyl ester obtained was 87%. Characterization of methyl ester was done with the following results : 0.858 g/cm3 density, 3.04 cSt viscosity, 3.5% water content, 12.3°C cloud point, 8.3°C pour point, 6.86 mgNaOH/g acid number, 164.4 mgNaOH/g saponification numbers, 108.4% iodine number, and 51.58 cetane number. The parameters do not meet SNI 04-7182-2006 for biodiesel were water  content and acid number. Methyl ester can be developed into blending biodiesel with the characteristic of density, viscosity, cloud point, pour point, saponification number, and cetane number which meet biodiesel standard according to SNI 04-7182-2006.  Keywords: biodiesel, oil losses, methyl ester, waste palm oil mill (POM), transesterification 

PENGEMBANGAN E-MODUL KIMIA BERBASIS KEMAMPUAN BERPIKIR KREATIF DENGAN MENGGUNAKAN KVISOFT FLIPBOOK MAKER

The aim of this research is to determining level of feasibility and response of students from the development of e-modules in chemistry course based on creative thinking ability using the Kvisoft Flipbook Maker on material electrolyte and non-electrolyte solution in SMA Negeri 9 Kota Bengkulu. The type of research used is R & D (Research & Development), which uses the ADDIE development model (analysis, design, development, implementation, evaluation) with the limitation of stage until implementation. The results of this research show that the chemistry-based E-Module based on creative very feasible and feasible to use with the validation results from media experts was 97.7%, material expert validation was 90.2%, readability the small group trials conducted by 9 students in class X MIPA 2 was 97.04% and student responses in the large group trial conducted by 25 students in class X MIPA 1 was 86.4% (very feasible category). This shows that e-modules in chemistry course based on the ability to think creatively by using the kvisoft flipbook maker are very suitable to be used in the learning proces

Development of E-Module Concerning The Effect of Solid Lipid Nanoparticle on Blood Glucose Mus musculus to Improve Students' Critical Thinking Skills

This study aims to develop an electronic module of teaching material supplements on the effect of solid lipid nanoparticle kebiul extract on blood glucose of Mus musculus to improve critical thinking skills of undergraduate students of Chemistry Education, Faculty of Teacher Training and Education University of Bengkulu. This type of research is Research and Development (R&amp;D) based on the ADDIE model (Analysis, Design, Development, Implementation, and Evaluation). The research was conducted by analyzing student needs for the development of e-module teaching material supplements and continued at the validation stage. The result of the validation of the 3D PageFlip Professional e-module was 89.78% in the very suitable category for use as a teaching material supplement. The validation of the test instrument for critical thinking was 88% with a very valid category and could be tested on students. The N-Gain result data was 0.68 in the medium category, so that the e-module developed is able to improve students' critical thinking skills. The result of the assessment on the student response questionnaire has a score of 89.8% with a very good category and can be disseminated online

CHARACTERISTIC OF BIODISESEL AND BIODIESEL BLENDING OF OIL LOSSES FROM LIQUID WASTE OF OIL PALM FACTORY

ABSTRACT  The aim of this study was to convert oil losses from palm oil mill (POM) liquid waste into methyl ester. Methyl ester as a result of conversion process was further developed into blending biodiesel. The research was conducted through several stages: 1). insolating oil losses of POM waste which taken from PT Bio Nusantara Bengkulu. Oil losses were degummed and bleached and then the free fatty acid was determined. 2). the conversion process  of oil losses into methyl ester was done through two stages of esterification reactions; using H2SO4 catalyst at 60oC for 2 hours and transesterification using NaOH catalyst at 55oC for 2 hours. 3). Methyl ester was developed as a blending  of biodiesel,  which is a mixture of methyl ester with diesel oil, with the percentages of methyl ester of 25%, 30%, 35%, 40%, and 45%. The yield of methyl ester obtained was 87%. Characterization of methyl ester was done with the following results : 0.858 g/cm3 density, 3.04 cSt viscosity, 3.5% water content, 12.3°C cloud point, 8.3°C pour point, 6.86 mgNaOH/g acid number, 164.4 mgNaOH/g saponification numbers, 108.4% iodine number, and 51.58 cetane number. The parameters do not meet SNI 04-7182-2006 for biodiesel were water  content and acid number. Methyl ester can be developed into blending biodiesel with the characteristic of density, viscosity, cloud point, pour point, saponification number, and cetane number which meet biodiesel standard according to SNI 04-7182-2006.  Keywords: biodiesel, oil losses, methyl ester, waste palm oil mill (POM), transesterification