Peginterferon maintenance therapy in patients with advanced hepatitis C to prevent hepatocellular carcinoma: The plot thickens

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Cultural landscape: Towards the design of a nocturnal lightscape

The current debate on the cultural landscape is focused on an inclusive definition. It proposes active enhancement practices and local planning tools that are also dedicated to the study of scenic-perceptive components and visual values. However, the current indications are limited to the definition of day images of sites, and are not based on investigations of the corresponding nocturnal images. The legislation and the recommendations in force in the field of lighting supply performance requirements, related to street and urban lighting, do not provide any indications regarding territorial contexts or widespread heritage sites. This paper presents a critical analysis of the lighting condition of different territorial contexts, places of widespread heritage, in particular with reference to the Italian context. The present situation has been investigated through a qualitative analysis, based on a comparison between day and night images, and a quantitative analysis, developed through a measurement campaign on representative case studies of the recurrent territorial context. In most cases, an absence of a specific lighting design strategy, aimed at defining a suitable nocturnal perception of the cultural landscape, has emerged from the collected data. The aim of the work has been to underline the importance of the study of nocturnal images and to show the possibility of developing an analysis and design methodology for these contexts. This approach should be based on a systemic vision, which should allow not only single monuments to be valorised, but also the places and landscapes that characterise a territory from a morphological and cultural point of view

Reply to: "The "pegylated" story continues – Perhaps because both ends (α2a and α2b) are true?"

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Post-liver transplantation graft biopsies should not be used to assess the IL28B donor genotype in HCV recipients.

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Study on Conservation Aspects Using LED Technology for Museum Lighting

The use of LEDs in museums is becoming more and more frequent. Benefits are claimed in terms of lighting quality, conservation and maintenance. Nonetheless the impact of LED light on collections preservation is not yet completely explored. The goal of this study was to evaluate, through exposure tests, the colour degradation and fading produced by LED: several white LEDs, with different colour temperature, and a traditional halogen lamp, were used to light up light-responsive samples. The results stressed the importance of the spectral distribution with respect to effective wavelengths in causing colour degradation, and in general white LEDs resulted more suitable, in terms of fading prevention, than traditional halogen light sources

Embodied Energy and Operational Energy Assessment in the Framework of Nearly Zero Energy Building and Building Energy Rating

The latest energy standards pertaining to buildings mainly focus on the reduction of Operational Energy (OE). The adoption of highly efficient energy production systems as well as of high performance materials is being encouraged more and more in order to achieve the Nearly Zero Energy Buildings target. Several studies have pointed-out that an increasing amount of materials are required in building construction. Their Embodied Energy (EE) can be assumed significant from a life-cycle perspective and in a NZEB approach. The present paper focuses on the assessment of the mutual impact of OE and EE on two residential buildings assumed as case studies

HCV genotype 3: An independent predictor of fibrosis progression in chronic hepatitis C

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La BNU de Turin

Nous aurions pu vous présenter les trésors de la Bibliothèque Vaticane mais des confrères de la presse grand public l\u27ont déjà fait mieux que nous. Nous avons préféré vous montrer comment fonctionne l’unique Bibliothèque nationale et universitaire d\u27Italie avec ce côté charmant et provincial qui caractérise les anciennes capitales de ce pays

Daylighting Design for Energy Saving in a Building Global Energy Simulation Context

A study on the impact that different daylighting solutions have on the global energy demand of a space is presented. The methodology relies on dynamic simulations carried out with Daysim and EnergyPlus used in synergy to perform a parametric study to assess the indoor daylighting conditions and the energy performance of rooms with different architectural features: room depth, window size, external obstruction angle and glazing visible transmittance. Furthermore, different lighting and shading control strategies were tested. The results of the study demonstrated that optimizing daylight can lead to a reduction of up to 30% in the global energy demand for a building