123 research outputs found

    Поняття погрому при вчиненні масових заворушень

    Get PDF
    Агаркова, А. В. Поняття погрому при вчиненні масових заворушень / Альона Віталіївна Агаркова // Актуальні проблеми сучасної науки в дослідженнях молодих учених : матеріали наук.-практ. конф. (Харків, 17 трав. 2016 р.) / МВС України, Харків. нац. ун-т внутр. справ. – Харків, 2016. – С. 11-14.Проаналізовано та визначено сутність поняття такій важливій формі об’єктивної сторони масових заворушень як погроми. Розглянуто співвідношення понять «погром» та «знищення майна».The essence of the concept of such an important form of the objective side of mass riots as pogroms has been analyzed and defined. The relationship between the concepts of "pogrom" and "destruction of property" is considered.Проанализирована и определена сущность понятия столь важной форме объективной стороны массовых беспорядков как погромы. Рассмотрено соотношение понятий «погром» и «уничтожение имущества»

    Становление уголовной ответственности за массовые беспорядки в странах СНГ

    Get PDF
    Агаркова, А. Становление уголовной ответственности за массовые беспорядки в странах СНГ / Алена Агаркова // Legea si viata = Закон и Жизнь : междунар. науч.-практ. журн. – 2015. – Aprilie. – P. 26–30.Проведено правовое исследование проблемы уголовной ответственности за массовые беспорядки в Украине и странах Содружества Независимых Государств. Сделаны выводы относительно общих и различных признаков состава преступления этих стран.A legal study of the problem of criminal responsibility for riots in Ukraine and the countries of the Commonwealth of Independent States was carried out. Conclusions are drawn regarding the general and various signs of the corpus delicti in these countries.Проведено правове дослідження проблеми кримінальної відповідальності за масові заворушення в Україні і країнах Співдружності Незалежних Держав. Зроблено висновки щодо загальних і різних ознак складу злочину цих країн

    Youth Forums as a Platform for Leisure Activity of Russian Youth

    Full text link
    Целью статьи является выявление мотивов и практик участия российской молодежи в молодежных образовательных форумах на примере «Тавриды» и «Территории смыслов». Проведено прикладное исследование, в котором применялись качественные методы: интервьюирование и традиционный контент-анализ документов. Использованы следующие подходы в научной экспликации молодежи: психоаналитический, структурно-функциональный и культурологический. Определена специфика молодежного форума как коммуникативной площадки досуговой активности молодежи. В ходе эмпирического исследования автором выявлены мотивы участия молодежи в образовательных форумах: развитие социального и человеческого капитала, профессиональных компетенций, самореализация, получение нового опыта в ходе «форумной» деятельности. Повседневными практиками молодежи являлись совместная деятельность, проживание в общем помещении, бытовые и пищевые практики, занятия спортом.The purpose of the article is to identify the motives and practices of participation of Russian youth in youth educational forums, using the example of “Tavrida” and “Territory of Meanings”. The author conducted an applied research in which qualitative methods were used: interviewing and traditional content analysis of documents. The following approaches were used in the scientific explication of youth: psychoanalytic, structural-functional and cultural. The specifics of the youth forum as a communicative platform for leisure activity of young people are determined. In the course of an empirical study, the author identified the motives for youth participation in educational forums: the development of social and human capital, professional competencies, self-realization, gaining new experience in the course of “forum” activities. The daily practices of young people were joint activities, living in a common room, household and food practices, sports

    Chloroviruses have a sweet tooth

    Get PDF
    Chloroviruses are large double-stranded DNA (dsDNA) viruses that infect certain isolates of chlorella-like green algae. They contain up to approximately 400 protein-encoding genes and 16 transfer RNA (tRNA) genes. This review summarizes the unexpected finding that many of the chlorovirus genes encode proteins involved in manipulating carbohydrates. These include enzymes involved in making extracellular polysaccharides, such as hyaluronan and chitin, enzymes that make nucleotide sugars, such as GDP-L-fucose and GDP-D-rhamnose and enzymes involved in the synthesis of glycans attached to the virus major capsid proteins. This latter process differs from that of all other glycoprotein containing viruses that traditionally use the host endoplasmic reticulum and Golgi machinery to synthesize and transfer the glycans

    Cerebroprotective effects of 2-ethyl-6-methyl-3-hydroxypyridine-2,6-dichlorophenyl(amino)phenylethanoic acid in the treatment of purulent meningitis

    Get PDF
    The aim of the study was to evaluate the cerebroprotective effects of a new pharmacological compound 2-ethyl-6-methyl-3-hydroxypyridine-2,6-dichlorophenyl(amino)phenylethanoic acid (EMHDPA) on the bacterial purulent meningitis in a model of experimental pneumococcal meningiti

    Evaluation of rat brain morphology following the induction of acute meningitis treated with Ceftriaxone

    Get PDF
    The present study aimed to assess the histological and immunohistochemical characteristics of the brain of rats that underwent induced acute purulent pneumococcal meningitis after antibiotic therapy with Ceftriaxon

    Prioritization of genes associated with the pathogenesis of leukosis in cattle

    Get PDF
    Selection by means of genetic markers is a promising approach to the eradication of infectious diseases in farm animals, especially in the absence of effective methods of treatment and prevention. Bovine leukemia virus (BLV) is spread throughout the world and represents one of the biggest problems for the livestock production and food security in Russia. However, recent genome-wide association studies have shown that sensitivity/resistance to BLV is polygenic. The aim of this study was to create a catalog of cattle genes and genes of other mammalian species involved in the pathogenesis of BLV-induced infection and to perform gene prioritization using bioinformatics methods. Based on manually collected information from a range of open sources, a total of 446 genes were included in the catalog of cattle genes and genes of other mammals involved in the pathogenesis of BLV-induced infection. The following criteria were used to prioritize 446 genes from the catalog: (1) the gene is associated with leukemia according to a genome-wide association study; (2) the gene is associated with leukemia according to a case-control study; (3) the role of the gene in leukemia development has been studied using knockout mice; (4) protein-protein interactions exist between the gene-encoded protein and either viral particles or individual viral proteins; (5) the gene is annotated with Gene Ontology terms that are overrepresented for a given list of genes; (6) the gene participates in biological pathways from the KEGG or REACTOME databases, which are over-represented for a given list of genes; (7) the protein encoded by the gene has a high number of protein-protein interactions with proteins encoded by other genes from the catalog. Based on each criterion, a rank was assigned to each gene. Then the ranks were summarized and an overall rank was determined. Prioritization of 446 candidate genes allowed us to identify 5 genes of interest (TNF, LTB, BOLA-DQA1, BOLA-DRB3, ATF2), which can affect the sensitivity/resistance of cattle to leukemia

    The Impact of Maternal Overweight on Hair Essential Trace Element and Mineral Content in Pregnant Women and Their Children

    Get PDF
    The aim of the present study was to investigate hair essential trace elements and mineral levels in 105 pregnant normal-weight (control) and 55 overweight and obese women in the third trimester of pregnancy, as well as in their children at the age of 9 months. The hair essential trace elements and mineral levels were assessed using inductively coupled plasma mass-spectrometry. Overweight pregnant women had significantly reduced Cr (- 24%; p = 0.047) and Zn (- 13%; p = 0.008) content, as well as elevated hair Na and K levels as compared to the controls. Children from overweight and obese mothers had lower hair Mo (- 18%; p = 0.017), Se (- 8%; p = 0.043), and V (- 24%; p = 0.028) levels, as well as elevated Sr content (19%; p = 0.025). Correlation analysis revealed a significant relationship between maternal and child hair levels of Co (r = 0.170; p = 0.038), Cu (r = 0.513; p < 0.001), Mn (r = 0.240; p = 0.003), and Na (r = 0.181; p = 0.027) in the whole sample. Pre-pregnancy maternal body mass index (BMI) positively correlated with maternal hair K (r = 0.336; p < 0.001) and Na (r = 0.212; p = 0.008) and negatively correlated with V (r = - 0.204; p = 0.011) and Zn (r = - 0.162; p = 0.045) levels. The results indicate that impaired trace element and mineral metabolism may play a role in the link between maternal obesity, complications of pregnancy and child's postnatal development. Hypothetically, dietary improvement may be used as a tool to reduce these risks. However, further experimental and clinical studies are required to investigate the relationship between obesity and trace element metabolism in pregnancy

    Reclassification of Subspecies of \u3ci\u3eAcidovorax avenae\u3c/i\u3e as \u3ci\u3eA. Avenae\u3c/i\u3e (Manns 1905) emend., \u3ci\u3eA. cattleyae \u3c/i\u3e (Pavarino, 1911)comb.nov., \u3ci\u3eA. citrulli\u3c/i\u3e Schaad et al.,1978)comb.nov., and proposal of \u3ci\u3eA. oryzae \u3c/i\u3esp. nov.

    Get PDF
    The bacterium Acidovorax avenae causes disease in a wide range of economically important monocotyledonous and dicotyledonous plants, including corn, rice, watermelon, anthurium, and orchids.Genotypic and phenotypic relatedness among strains of phytopathogenic A. avenae sub sp. avenae, A. avenae sub sp. citrulli, A. avenae subsp. cattleyae and A. konjaci, as well as all other Acidovorax species, including A. facilis, the type strain of Acidovorax, was determined.The16s rDNA sequencing confirmed previous studies showing the environmental species to be very distant from the phytopathogenic species. DNA/DNA reassociation assays on the different strains of A. avenae revealed four(A, B, C, and D) distinct genotypes. Taxon A included six A. avenae subsp. avenaestrains from corn that had a mean reciprocal similarity of 81%; taxon B included six A. avenae sub sp. avenae strains from rice that had a mean reciprocal similarity of 97%; taxon C contained 11 A. avenae sub sp. citrulli strains from cucurbits (cantaloupe, watermelon, and pumpkin) that had a mean reciprocal similarity of 88%, and taxon D contained four A. avenae sub sp. cattleyae strains from orchids that had a mean similarity of 98%

    Identification of a Chlorovirus PBCV-1 Protein Involved in Degrading the Host Cell Wall during Virus Infection

    Get PDF
    Chloroviruses are unusual among viruses infecting eukaryotic organisms in that they must, like bacteriophages, penetrate a rigid cell wall to initiate infection. Chlorovirus PBCV-1 infects its host, Chlorella variabilis NC64A by specifically binding to and degrading the cell wall of the host at the point of contact by a virus-packaged enzyme(s). However, PBCV-1 does not use any of the five previously characterized virus-encoded polysaccharide degrading enzymes to digest the Chlorella host cell wall during virus entry because none of the enzymes are packaged in the virion. A search for another PBCV-1-encoded and virion-associated protein identified protein A561L. The fourth domain of A561L is a 242 amino acid C-terminal domain, named A561LD4, with cell wall degrading activity. An A561LD4 homolog was present in all 52 genomically sequenced chloroviruses, infecting four different algal hosts. A561LD4 degraded the cell walls of all four chlorovirus hosts, as well as several non-host Chlorella spp. Thus, A561LD4 was not cell-type specific. Finally, we discovered that exposure of highly purified PBCV-1 virions to A561LD4 increased the specific infectivity of PBCV-1 from about 25–30% of the particles forming plaques to almost 50%. We attribute this increase to removal of residual host receptor that attached to newly replicated viruses in the cell lysates
    corecore