Marketing mix for e-commerce

The relevance of the analyzed issue is caused by the need to study the process of transformation of marketing in e-commerce, as the active involvement of business organizations in the field of e-business is often accompanied by problems of applying the usual marketing tools in a virtual environment. The article seeks to identify changes in the elements of the marketing mix in e-commerce in accordance with the trend of e-business and Internet technology. The leading approach to the study of this issue is the marketing model 7P, allowing structuring the changes in a complex of marketing tools with regard to trade and information services of online stores. The results of research were: to establish the determining role of technology and information support of consumers; to identify the areas of transformation of the marketing mix in e-commerce, demonstrating the significant influence of consumers on the content of 7P and personalize the supply of goods and services. The article may be useful for online stores in case of marketing strategy development, identification of the most important elements of 7P, assessment of marketing effectiveness and optimization of marketing costs. © 2016 Pogorelova et al

Nitrogen-deficient and iron-rich associated absorbers with oversolar metallicities towards the quasar HE0141-3932

HE0141-3932 (zem=1.80) is a bright blue radio-quite quasar which reveals an emission line spectrum with an unusually weak Ly-alpha line. In addition, large redshift differences (Delta z=0.05) are observed between high ionization and low ionization emission lines. Absorption systems identified at z=1.78, 1.71, and 1.68 show mild oversolar metallicities (Z ~= 1-2Zsolar) and can be attributed to the associated gas clouds ejected from the circumnuclear region. The joint analysis of the emission and absorption lines leads to the conclusion that this quasar is seen almost pole-on. Its apparent luminosity may be Doppler boosted by ~10 times. The absorbing gas shows high abundance of Fe, Mg, and Al ([Fe, Mg, Al/C] ~= 0.15+/-0.10) along with underabundance of N ([N/C]<=-0.5). This abundance pattern is at variance with current chemical evolution models of QSOs predicting [N/C]>0 and [Fe/C]<0 at Z ~ Zsolar. Full details of this work are given in Reimers et al. (2005).Comment: 2 pages, to appear in the Proceed. of IAU Symp.228 "From Lithium to Uranium: Elemental Tracers of Early Cosmic Evolution", eds. V.Hill, P.Francois and F.Prima

HE 0141-3932: a bright QSO with an unusual emission line spectrum and associated absorption

HE 0141-3932 (zem = 1.80) is a bright blue radio-quite quasar with an unusually weak Ly-alpha emission line. Large redshift differences (Delta z = 0.05) are observed between high ionization and low ionization emission lines. Absorption systems identified at zabs = 1.78, 1.71, and 1.68 show mild oversolar metallicities (Z ~= 1-2Zsolar) and can be attributed to the associated gas clouds ejected from the circumnuclear region. The joint analysis of the emission and absorption lines leads to the conclusion that this quasar is seen almost pole-on. Its apparent luminosity may be Doppler boosted by ~10 times. The absorbing gas shows a high abundance of Fe, Mg and Al ([Fe, Mg, Al/C] ~= 0.15 +/- 0.10) along with underabundance of N ([N/C] <= -0.5). This abundance pattern is at variance with current chemical evolution models of QSOs predicting [N/C] >= 0$ and [Fe/C] < 0 at Z ~ Zsolar.Comment: 12 pages, 6 figures, accepted for publication in A&

Metal abundances and kinematics of quasar absorbers.- I. Absorption systems toward J2233-606

The metal line profiles of different ions observed in high HI column density systems [N(HI) > 10^{16} cm^{-2}] in quasar spectra can be used to constrain the ionization structure and kinematic characteristics of the absorbers. For these purposes, a modified Monte Carlo Inversion (MCI) procedure was applied to the study of three absorption systems in the spectrum of the HDF-South quasar J2233-606 obtained with the UVES spectrograph at the VLT/Kueyen telescope. The MCI does not confirm variations of metal abundances within separate systems which were discussed in the literature. Instead, we found that an assumption of a homogeneous metal content and a unique photoionizing background is sufficient to describe the observed complex metal profiles. It was also found that the linear size L and the line-of-sight velocity dispersion sigma_v measured within the absorbers obey a scaling relation, namely, sigma_v increases with increasing L, and that metal abundance is inversely proportional to the linear size of the system: the highest metallicity was measured in the system with the smallest L.Comment: 10 pages, 7 ps figures, accepted to A&

Regulatory Profile Changes of Lymphocytes and Peripheral Blood Monocytes in Children with Candidiasis Associated with Chronic Somatic Diseases

© 2017, Springer Science+Business Media, LLC. In this paper, we report results of the study of immune parameters with the assessment of regulatory and effector subpopulations of lymphocytes and monocytes with candidiasis in children with chronic somatic diseases (secondary pyelonephritis and obstructive diseases of the upper gastrointestinal tract). Candidiasis was diagnosed by the rising level of circulating Candida albicans mannan antigen and culture mycological research. It was found that the persistence of fungi is associated with differentiated regulatory changes in the structure of subpopulations of lymphocytes and monocytes with preferential increase of immunosuppressive cells (CD4+CD25+hi, CD3+CD16/56+, CD3−CD8+, CD3+4 amid reduction of effector subpopulations of lymphocytes and antigen presenting cells associated with Th1 immune response profile

Image of Muslim women represented by means of modern English

The aim of the study is to show the image of Muslim women and to identify their position at the language leve

New membrane carrier for glutamic acid based on p-tert-butylcalix[4]arene 1,3-disubstituted at the lower rim

Calix[4]arenes 1,3-disubstituted at the lower rim were synthesized and their receptor ability toward dicarboxylic, α-hydroxy and amino acids was investigated. A new synthetic receptor for glutamic acid based on 1,3-disubstituted calix[4]arene was suggested. © 2009

Эффективность иммуномодулирующей терапии внебольничной пневмонии у часто болеющих детей

The aim of the work is to study the indicators of local and systemic immunity in frequently ill children with community-acquired therapy to improve the methods of therapy. 55 children with community-acquired pneumonia and recurrent respiratory diseases (8 or more per year) aged from 3 to 7 years were examined. In the main group (n = 30), on the background of standard therapy, the children received the immunomodulator azoximerе bromide. In the comparison group (n = 25), the children received conventional therapy. Assessment of the state of systemic and mucosal immunity was carried out in dynamics before treatment and after therapy. It was shown that the inclusion of azoxymere bromide leads to an optimal correction of cellular immunity, phagocytic activity of neutrophils, as well as systemic and local cytokine profile. Clinical efficacy is manifested by a reduction in the duration of the febrile period, more rapid relief of intoxication syndromes, respiratory and local pulmonary changes.Цель работы — изучение показателей местного и системного иммунитета у часто болеющих детей с внебольничной пневмонией для совершенствования методов терапии. Обследовано 55 детей с внебольничной пневмонией и рекуррентными респираторными заболеваниями (8 и более в год) в возрасте от 3 до 7 лет жизни. В основной группе (n = 30) на фоне стандартной терапии дети получали иммуномодулятор азоксимера бромид (Полиоксидоний). В группе сравнения (n = 25) дети получали традиционную терапию. Оценка состояния системного и мукозального иммунитета проводилась в динамике до и после лечения. Показано, что включение в терапию внебольничной пневмонии у детей азоксимера бромида приводит к оптимальной коррекции показателей клеточного иммунитета, фагоцитарной активности нейтрофилов, а также системного и локального цитокинового профиля. Клиническая эффективность препарата проявляется сокращением длительности лихорадочного периода и интоксикации, более быстром купировании респираторных и локальных легочных изменений

INVESTIGATION OF THE PROPERTIES OF COMPOSITES BASED ON ALUMINUM ALLOY, OBTAINED BY MODIFICATION WITH NANOPOWDER PSEUDOLIGATURES Si3N4, ALN

Работа заключалась в исследовании свойств дисперсно-упрочненных композиционных материалов на основе алюминия. В качестве дисперсных частиц применяется нитрид кремния Si3N4 и нитрид алюминия AlN размером частиц 150 нанометров. Слитки, полученные в результате модифицирования, подвергались микроисследованию, исследованию на твердость и испытанию на разрыв. Результаты, полученные в ходе механических испытаний, а также микроструктуры образцов представлены в работе и свидетельствуют об упрочнении исходного сплава.The work consisted in investigating the properties of dispersion-hardened composite materials based on aluminum. Silicon nitride Si3N4 and AlN aluminum nitride with a particle size of 150 nanometers are used as dispersed articles. The ingots obtained as a result of the modification were subjected to microanalysis, hardness and tensile testing. The results obtained in the course of mechanical tests, as well as the microstructure of the samples are presented in the work and indicate the hardening of the initial alloy