84 research outputs found
Π‘Π΅ΠΌΠ°Π½ΡΠΈΡΠ½Ρ Π·ΠΌΡΠ½ΠΈ Π² Π»Π΅ΠΊΡΠΈΡΠ½ΠΎΠΌΡ ΡΠΊΠ»Π°Π΄Ρ ΡΠΎΡΡΠΉΡΡΠΊΠΎΡ ΡΠ° ΡΠΊΡΠ°ΡΠ½ΡΡΠΊΠΎΡ ΠΌΠΎΠ²
ΠΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ Π²ΡΡΠΈΡΠ»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΡΠ΅Ρ
Π½ΠΈΠΊΠΈ ΠΈ ΡΠ°Π΄ΠΈΠΎΡΠ»Π΅ΠΊΡΡΠΎΠ½ΠΈΠΊΠΈ ΡΠΏΠΎΡΠΎΠ±ΡΡΠ²ΠΎΠ²Π°Π»ΠΎ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ Π³ΡΡΠΏΠΏΡ Π»Π΅ΠΊΡΠΈΡΠ΅ΡΠΊΠΈΡ
Π΅Π΄ΠΈΠ½ΠΈΡ. ΠΠΎΠΌΠΈΠ½Π°ΡΠΈΡ Π½ΠΎΠ²ΡΡ
ΡΠ²Π»Π΅Π½ΠΈΠΉ ΠΈ ΠΏΠΎΠ½ΡΡΠΈΠΉ ΡΠ²Π»ΡΠ΅ΡΡΡ Π°ΠΊΡΡΠ°Π»ΡΠ½ΠΎΠΉ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠΎΠΉ Π½ΡΠ½Π΅ΡΠ½Π΅Π³ΠΎ ΡΡΠ°ΠΏΠ° ΡΠ°Π·Π²ΠΈΡΠΈΡ ΡΠ·ΡΠΊΠ°. ΠΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΡΠ΅ΠΌΠ°Π½ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π½Π°ΠΏΠΎΠ»Π½Π΅Π½ΠΈΡ β ΡΡΠΎ ΠΎΠ΄ΠΈΠ½ ΠΈΠ· ΡΠΏΠΎΡΠΎΠ±ΠΎΠ²
ΡΠ΅ΡΠ΅Π½ΠΈΡ Π΄Π°Π½Π½ΠΎΠΉ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ. Π Π°ΡΡΠΈΡΠ΅Π½ΠΈΠ΅ ΠΈΠ»ΠΈ ΡΡΠΆΠ΅Π½ΠΈΠ΅ ΡΠ΅ΠΌΠ°Π½ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΎΠ±ΡΠ΅ΠΌΠ°
ΡΠ»ΠΎΠ² ΡΠΏΠΎΡΠΎΠ±ΡΡΠ²ΡΠ΅Ρ ΠΎΠ±ΠΎΠ³Π°ΡΠ΅Π½ΠΈΡ Π»Π΅ΠΊΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ, Π° ΠΈΠΌΠ΅Π½Π½ΠΎ ΡΠ΅ΡΠΌΠΈΠ½ΠΎΠ»ΠΎΠ³ΠΈΠΈ.ΠΠΈΠΊΠΎΡΠΈΡΡΠ°Π½Π½Ρ ΠΎΠ±ΡΠΈΡΠ»ΡΠ²Π°Π»ΡΠ½ΠΎΡ ΡΠ΅Ρ
Π½ΡΠΊΠΈ ΡΠ° ΡΠ°Π΄ΡΠΎΠ΅Π»Π΅ΠΊΡΡΠΎΠ½ΡΠΊΠΈ ΡΠΏΡΠΈΡΠΈΠ½ΠΈΠ»ΠΎ
ΡΠΎΡΠΌΡΠ²Π°Π½Π½Ρ ΡΠΏΠ΅ΡΡΠ°Π»ΡΠ½ΠΎΡ Π³ΡΡΠΏΠΈ Π»Π΅ΠΊΡΠΈΡΠ½ΠΈΡ
ΠΎΠ΄ΠΈΠ½ΠΈΡΡ. ΠΠΎΠΌΡΠ½Π°ΡΡΡ Π½ΠΎΠ²ΠΈΡ
ΡΠ²ΠΈΡ ΡΠ°
ΠΏΠΎΠ½ΡΡΡ Ρ Π°ΠΊΡΡΠ°Π»ΡΠ½ΠΎΡ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠΎΡ ΡΠ΅ΠΏΠ΅ΡΡΡΠ½ΡΠΎΠ³ΠΎ Π΅ΡΠ°ΠΏΡ ΡΠΎΠ·Π²ΠΈΡΠΊΡ ΠΌΠΎΠ²ΠΈ. ΠΠΌΡΠ½Π° ΡΠ΅ΠΌΠ°Π½ΡΠΈΡΠ½ΠΎΠ³ΠΎ ΠΎΠ±'ΡΠΌΡ β ΡΠ΅ ΠΎΠ΄ΠΈΠ½ ΡΠ· Π·Π°ΡΠΎΠ±ΡΠ² Π²ΠΈΡΡΡΠ΅Π½Π½Ρ Π΄Π°Π½ΠΎΡ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠΈ. ΠΠ²ΡΠΆΠ΅Π½Π½Ρ
Π°Π±ΠΎ ΡΠΎΠ·ΡΠΈΡΠ΅Π½Π½Ρ ΡΠ΅ΠΌΠ°Π½ΡΠΈΡΠ½ΠΎΠ³ΠΎ Π½Π°ΠΏΠΎΠ²Π½Π΅Π½Π½Ρ ΡΠΏΡΠΈΡΡ Π·Π±Π°Π³Π°ΡΠ΅Π½Π½Ρ Π»Π΅ΠΊΡΠΈΡΠ½ΠΎΡ ΡΠΈΡΡΠ΅ΠΌΠΈ, Π° ΡΠ°ΠΌΠ΅ ΡΠ΅ΡΠΌΡΠ½ΠΎΠ»ΠΎΠ³ΡΡ.Using of radio-electronic devices forced the formation of a special group of lexical
units. The nomination of new processes and notions is an actual problem of today's
language development. Semantic changes of existing units is one of the decisions
of the problem. Widening and narrowing of semantic meanings promotes the
enrichment of lexical system, especially the system of terminology
Haptoglobin related protein levels are correlated with haptoglobin levels in A) Gabonese and B) Caucasian children.
<p>Scatterplot of raw Hpr values (mg/ml) plotted against raw Hp values (mg/ml). Associations were assessed by Spearmans rho. Hpr was positively correlated with Hp in A) Gabonese children (r<sub>s</sub>β=β0.29, <i>P</i><0.001), and B) Caucasian children (r<sub>s</sub>β=β0.51, <i>P</i><0.001).</p
Field study design, data analysis and modeling framework.
<p>N = number of observations.</p
Hpr levels in Gabonese and Caucasian children.
<p>Values represent median [interquartile range]. P-values represent comparisons between Caucasians and Gabonese children.</p
Submicroscopic placental infection by non-<i>falciparum Plasmodium</i> spp.
<div><p>Background</p><p>Among the <i>Plasmodium</i> species that infect humans, adverse effects of <i>P</i>. <i>falciparum</i> and <i>P</i>. <i>vivax</i> have been extensively studied and reported with respect to poor outcomes particularly in first time mothers and in pregnant women living in areas with unstable malaria transmission. Although, other non-<i>falciparum</i> malaria infections during pregnancy have sometimes been reported, little is known about the dynamics of these infections during pregnancy.</p><p>Methods and findings</p><p>Using a quantitative PCR approach, blood samples collected from Beninese pregnant women during the first antenatal visit (ANV) and at delivery including placental blood were screened for <i>Plasmodium</i> spp. Risk factors associated with <i>Plasmodium spp</i>. infection during pregnancy were assessed as well as the relationships with pregnancy outcomes.</p><p><i>P</i>. <i>falciparum</i> was the most prevalent <i>Plasmodium</i> species detected during pregnancy, irrespective either of parity, of age or of season during which the infection occurred. Although no <i>P</i>. <i>vivax</i> infections were detected in this cohort, <i>P</i>. <i>malariae</i> (9.2%) and <i>P</i>. <i>ovale</i> (5.8%) infections were observed in samples collected during the first ANV. These non-<i>falciparum</i> infections were also detected in maternal peripheral blood (1.3% for <i>P</i>. <i>malariae</i> and 1.2% for <i>P</i>. <i>ovale</i>) at delivery. Importantly, higher prevalence of <i>P</i>. <i>malariae</i> (5.5%) was observed in placental than peripheral blood while that of <i>P</i>. <i>ovale</i> was similar (1.8% in placental blood). Among the non-<i>falciparum</i> infected pregnant women with paired peripheral and placental samples, <i>P</i>. <i>malariae</i> infections in the placental blood was significantly higher than in the peripheral blood, suggesting a possible affinity of <i>P</i>. <i>malariae</i> for the placenta. However, no assoctiation of non-<i>falciparum</i> infections and the pregnancy outcomes was observed</p><p>Conclusions</p><p>Overall this study provided insights into the molecular epidemiology of <i>Plasmodium</i> spp. infection during pregnancy, indicating placental infection by non-<i>falciparum Plasmodium</i> and the lack of association of these infections with adverse pregnancy outcomes.</p></div
Risk factors for <i>P</i>. <i>falciparum</i> and non-<i>falciparum</i> malaria mixed infections at enrolment.
<p>Risk factors for <i>P</i>. <i>falciparum</i> and non-<i>falciparum</i> malaria mixed infections at enrolment.</p
Association of <i>Plasmodium</i> spp. infections at delivery with pregnancy outcomes.
<p>Association of <i>Plasmodium</i> spp. infections at delivery with pregnancy outcomes.</p
Acute phase protein levels, parasitaemia and frequency of haptoglobin polymorphisms in Gabonese children.
<p>Continuous data are shown as median value [inter-quartile range] or mean (standard deviation) and categorical data are n (%). Note for C-reactive protein, albumin and plasmodium prevalence nβ=β550.</p>1<p>C-reactive protein >10 Β΅g/mL was the cut-off used to define an acute phase response <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049816#pone.0049816-Gabay1" target="_blank">[17]</a>.</p>2<p>The cut off value for hypohaptoglobinaemia is <0.18 mg/mL <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049816#pone.0049816-Kunitake1" target="_blank">[29]</a>.</p>3<p>The cut off value for low albumin is <35 mg/mL <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049816#pone.0049816-McGuire1" target="_blank">[30]</a>.</p>4<p>The frequency of species in this population has been published previously <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049816#pone.0049816-Fowkes1" target="_blank">[21]</a>.</p
Univariate assessments of the influence of variables of interest on Hpr levels in Gabonese children.
<p>Coefficients are from univariate general linear models investigating the association between variables of interest and log(Haptoglobin-related protein) values.</p
Risk factors for <i>P</i>. <i>falciparum</i> malaria infections at enrolment.
<p>Risk factors for <i>P</i>. <i>falciparum</i> malaria infections at enrolment.</p
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